Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
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{"title"=>"Integrative annotation of 21,037 human genes validated by full-length cDNA clones", "type"=>"journal", "authors"=>[{"first_name"=>"Tadashi", "last_name"=>"Imanishi", "scopus_author_id"=>"7101939542"}, {"first_name"=>"Takeshi", "last_name"=>"Itoh", "scopus_author_id"=>"35378001500"}, {"first_name"=>"Yutaka", "last_name"=>"Suzuki", "scopus_author_id"=>"55626680600"}, {"first_name"=>"Claire", "last_name"=>"O'Donovan", "scopus_author_id"=>"55252050600"}, {"first_name"=>"Satoshi", "last_name"=>"Fukuchi", "scopus_author_id"=>"8071836400"}, {"first_name"=>"Kanako O.", "last_name"=>"Koyanagi", "scopus_author_id"=>"9842502200"}, {"first_name"=>"Roberto A.", "last_name"=>"Barrero", "scopus_author_id"=>"8880390500"}, {"first_name"=>"Takuro", "last_name"=>"Tamura", "scopus_author_id"=>"35376560600"}, {"first_name"=>"Yumi", "last_name"=>"Yamaguchi-Kabata", "scopus_author_id"=>"6508022852"}, {"first_name"=>"Motohiko", "last_name"=>"Tanino", "scopus_author_id"=>"56269405500"}, 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"abstract"=>"The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigation have been used to elucidate the structure and function of the genes in the human genome. Even so, gene prediction remains a difficult task, as the varieties of transcripts of a gene may vary to a great extent. We thus performed an exhaustive integrative characterization of 41,118 full-length cDNAs that capture the gene transcripts as complete functional cassettes, providing an unequivocal report of structural and functional diversity at the gene level. Our international collaboration has validated 21,037 human gene candidates by analysis of high-quality full-length cDNA clones through curation using unified criteria. This led to the identification of 5,155 new gene candidates. It also manifested the most reliable way to control the quality of the cDNA clones. We have developed a human gene database, called the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/). It provides the following: integrative annotation of human genes, description of gene structures, details of novel alternative splicing isoforms, non-protein-coding RNAs, functional domains, subcellular localizations, metabolic pathways, predictions of protein three-dimensional structure, mapping of known single nucleotide polymorphisms (SNPs), identification of polymorphic microsatellite repeats within human genes, and comparative results with mouse full-length cDNAs. The H-InvDB analysis has shown that up to 4% of the human genome sequence (National Center for Biotechnology Information build 34 assembly) may contain misassembled or missing regions. We found that 6.5% of the human gene candidates (1,377 loci) did not have a good protein-coding open reading frame, of which 296 loci are strong candidates for non-protein-coding RNA genes. In addition, among 72,027 uniquely mapped SNPs and insertions/deletions localized within human genes, 13,215 nonsynonymous SNPs, 315 nonsense SNPs, and 452 indels occurred in coding regions. Together with 25 polymorphic microsatellite repeats present in coding regions, they may alter protein structure, causing phenotypic effects or resulting in disease. The H-InvDB platform represents a substantial contribution to resources needed for the exploration of human biology and pathology.", "link"=>"http://www.mendeley.com/research/integrative-annotation-21037-human-genes-validated-fulllength-cdna-clones-1", "reader_count"=>140, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>20, "Librarian"=>1, "Researcher"=>58, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>15, "Student > Master"=>10, "Other"=>10, "Student > Bachelor"=>5, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>2, "Professor"=>14}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>20, "Librarian"=>1, "Researcher"=>58, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>15, "Student > Master"=>10, "Other"=>10, "Student > Bachelor"=>5, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>2, "Professor"=>14}, "reader_count_by_subject_area"=>{"Unspecified"=>3, "Engineering"=>1, "Biochemistry, Genetics and Molecular Biology"=>17, "Mathematics"=>1, "Agricultural and Biological Sciences"=>94, "Medicine and Dentistry"=>15, "Neuroscience"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>2, "Psychology"=>1, "Computer Science"=>2, "Immunology and Microbiology"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>15}, "Neuroscience"=>{"Neuroscience"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>2}, "Psychology"=>{"Psychology"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>94}, "Computer Science"=>{"Computer Science"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>17}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>3}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"Netherlands"=>1, "Sweden"=>1, "United States"=>7, "Norway"=>1, "Japan"=>7, "Brazil"=>2, "United Kingdom"=>5, "Chile"=>1, "Australia"=>1, "France"=>2, "Germany"=>3, "Spain"=>1}, "group_count"=>4}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/4417804"], "description"=>"<p>The Features of Predicted ORFs</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740513, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Features_of_Predicted_ORFs/2740513", "title"=>"The Features of Predicted ORFs", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417741"], "description"=>"<p>The numbers of representative H-Inv cDNAs with sequence homology to other species' proteins (<i>E</i> < 10<sup>−5</sup>) were calculated. The cDNAs for which we could not assign any functions were discarded. Mammalian species were excluded from the “animal” group. “Eukaryote” represents eukaryotic species other than those included in the mammal, animal, fungi, and plant groups. See also Table S7.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740450, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.g006", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Functional_Classification_of_H_Inv_Proteins_That_Are_Homologous_to_Proteins_in_Each_Taxonomic_Group/2740450", "title"=>"The Functional Classification of H-Inv Proteins That Are Homologous to Proteins in Each Taxonomic Group", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417774"], "description"=>"<p>Summary of cDNA Resources</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740483, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Summary_of_cDNA_Resources/2740483", "title"=>"Summary of cDNA Resources", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417723"], "description"=>"<p>The diagram illustrates the human curation pipeline to classify H-Inv proteins into five similarity categories; Category I , II, III, IV, and V proteins.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>634534, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>["https://dx.doi.org/10.1371/journal.pbio.0020162.g004"], "stats"=>{"downloads"=>2, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Schematic_Diagram_of_Human_Curation_for_H_Inv_Proteins_/634534", "title"=>"Schematic Diagram of Human Curation for H-Inv Proteins", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417699"], "description"=>"<p>The cDNAs were mapped to the genome and clustered into loci. The remaining unmapped cDNAs were clustered based upon the grouping of significantly similar cDNAs.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>633702, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>["https://dx.doi.org/10.1371/journal.pbio.0020162.g001"], "stats"=>{"downloads"=>1, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Procedure_for_Mapping_and_Clustering_the_H_Inv_cDNAs_/633702", "title"=>"Procedure for Mapping and Clustering the H-Inv cDNAs", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417810"], "description"=>"<p>The Numbers of SNPs and indels Occurring in the Representative cDNAs</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740519, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t005", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Numbers_of_SNPs_and_indels_Occurring_in_the_Representative_cDNAs/2740519", "title"=>"The Numbers of SNPs and indels Occurring in the Representative cDNAs", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417717"], "description"=>"<p>Exons are presented from the 5′ end, with those shared by AS variants aligned vertically. The AS variants, with accession numbers AK095301 and BC007828, are aligned to the SCOP domain d.136.1.1 and corresponding PDB structure 1byr. Helices and beta sheets are red and yellow, respectively. Green bars indicate regions aligned to the PDB structure, while open rectangles represent gaps in the alignments. AK095301 is aligned to the entire PDB structure shown, while BC007828 is lacking the alignment to the purple segment of the structure.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>634345, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>["https://dx.doi.org/10.1371/journal.pbio.0020162.g003"], "stats"=>{"downloads"=>0, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_An_Example_of_Different_Structures_Encoded_by_AS_Variants_/634345", "title"=>"An Example of Different Structures Encoded by AS Variants", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417786"], "description"=>"<p>The Clustering Results of Human FLcDNAs onto the Human Genome</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740495, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Clustering_Results_of_Human_FLcDNAs_onto_the_Human_Genome/2740495", "title"=>"The Clustering Results of Human FLcDNAs onto the Human Genome", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417819"], "description"=>"<p>The Numbers of Microsatellite Repeat Motifs That Occurred in the Representative cDNAs</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740528, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t006", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Numbers_of_Microsatellite_Repeat_Motifs_That_Occurred_in_the_Representative_cDNAs/2740528", "title"=>"The Numbers of Microsatellite Repeat Motifs That Occurred in the Representative cDNAs", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417762"], "description"=>"<p>Results for 5′ UTRs presented above and for 3′ UTRs below. The whole mRNA sequences were aligned using a semiglobal algorithm as implemented in the map program (Huang 1994) with the following parameters: match 10, mismatch −3, gap opening penalty −50, gap extension penalty −5, and longest penalized gap 10; the terminal gaps are not penalized at all. A window size of 20 bp was used with a step of 10 bp. The analysis window was moved upstream and downstream of start and stop codons, respectively. The normalized score for a given window is calculated as a fraction of an average score for all UTRs in a given window over the maximum score observed in all 5′ or 3′ UTRs, respectively.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740465, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.g007", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Window_Analysis_of_Similarity_between_Human_and_Mouse_UTRs/2740465", "title"=>"Window Analysis of Similarity between Human and Mouse UTRs", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417537", "https://ndownloader.figshare.com/files/4417633", "https://ndownloader.figshare.com/files/4417639", "https://ndownloader.figshare.com/files/4417651", "https://ndownloader.figshare.com/files/4417657", "https://ndownloader.figshare.com/files/4417663", "https://ndownloader.figshare.com/files/4417669", "https://ndownloader.figshare.com/files/4417675", "https://ndownloader.figshare.com/files/4417684", "https://ndownloader.figshare.com/files/4417687", "https://ndownloader.figshare.com/files/4417627", "https://ndownloader.figshare.com/files/4417621", "https://ndownloader.figshare.com/files/4417612", "https://ndownloader.figshare.com/files/4417543", "https://ndownloader.figshare.com/files/4417558", "https://ndownloader.figshare.com/files/4417573", "https://ndownloader.figshare.com/files/4417576", "https://ndownloader.figshare.com/files/4417582", "https://ndownloader.figshare.com/files/4417591", "https://ndownloader.figshare.com/files/4417597", "https://ndownloader.figshare.com/files/4417603", "https://ndownloader.figshare.com/files/4417609", "https://ndownloader.figshare.com/files/4417693"], "description"=>"<div><p>The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this area is still limited. Several lines of investigation have been used to elucidate the structure and function of the genes in the human genome. Even so, gene prediction remains a difficult task, as the varieties of transcripts of a gene may vary to a great extent. We thus performed an exhaustive integrative characterization of 41,118 full-length cDNAs that capture the gene transcripts as complete functional cassettes, providing an unequivocal report of structural and functional diversity at the gene level. Our international collaboration has validated 21,037 human gene candidates by analysis of high-quality full-length cDNA clones through curation using unified criteria. This led to the identification of 5,155 new gene candidates. It also manifested the most reliable way to control the quality of the cDNA clones. We have developed a human gene database, called the H-Invitational Database (H-InvDB; <a href=\"http://www.h-invitational.jp/\" target=\"_blank\">http://www.h-invitational.jp/</a>). It provides the following: integrative annotation of human genes, description of gene structures, details of novel alternative splicing isoforms, non-protein-coding RNAs, functional domains, subcellular localizations, metabolic pathways, predictions of protein three-dimensional structure, mapping of known single nucleotide polymorphisms (SNPs), identification of polymorphic microsatellite repeats within human genes, and comparative results with mouse full-length cDNAs. The H-InvDB analysis has shown that up to 4% of the human genome sequence (National Center for Biotechnology Information build 34 assembly) may contain misassembled or missing regions. We found that 6.5% of the human gene candidates (1,377 loci) did not have a good protein-coding open reading frame, of which 296 loci are strong candidates for non-protein-coding RNA genes. In addition, among 72,027 uniquely mapped SNPs and insertions/deletions localized within human genes, 13,215 nonsynonymous SNPs, 315 nonsense SNPs, and 452 indels occurred in coding regions. Together with 25 polymorphic microsatellite repeats present in coding regions, they may alter protein structure, causing phenotypic effects or resulting in disease. The H-InvDB platform represents a substantial contribution to resources needed for the exploration of human biology and pathology.</p></div>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>153364, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. 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  • {"files"=>["https://ndownloader.figshare.com/files/4417792"], "description"=>"<p>Statistics Obtained from the Functional Annotation Results</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740501, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.t003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Statistics_Obtained_from_the_Functional_Annotation_Results/2740501", "title"=>"Statistics Obtained from the Functional Annotation Results", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417708"], "description"=>"<p>The mapped H-Inv cDNAs, the RefSeq curated mRNAs (accession prefixes NM and NR), and the RefSeq model mRNAs (accession prefixes XM and XR) provided by the genome annotation process were clustered based on the genome position. The numbers of loci that were identified by clustering are shown.</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>634017, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>["https://dx.doi.org/10.1371/journal.pbio.0020162.g002"], "stats"=>{"downloads"=>2, "page_views"=>46, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_Comparison_of_the_Mapped_H_Inv_FLcDNAs_and_the_RefSeq_mRNAs_/634017", "title"=>"A Comparison of the Mapped H-Inv FLcDNAs and the RefSeq mRNAs", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2004-04-20 10:52:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/4417732"], "description"=>"<p>Candidate non-protein-coding genes were compared with the human genome, ESTs, cDNA 3′-end features and the locus genomic environment. The candidates were then classified into four categories: hold (cDNAs improperly mapped onto the human genome); uncharacterized transcripts (transcripts overlapping a sense gene or located within 5 kb of a neighboring gene with EST support); putative ncRNAs (multiexon or single exon transcripts supported by ESTs or 3′-end features); and unclassifiable (possible genomic fragments).</p>", "links"=>[], "tags"=>["gene candidates", "genome sequence", "coding regions", "25 polymorphic microsatellite", "RNA", "315 nonsense SNPs", "cDNA clones"], "article_id"=>2740441, "categories"=>["Genetics", "Molecular Biology", "Evolutionary Biology", "Biological Sciences not elsewhere classified", "Infectious Diseases"], "users"=>["Tadashi Imanishi", "Takeshi Itoh", "Yutaka Suzuki", "Claire O'Donovan", "Satoshi Fukuchi", "Kanako O Koyanagi", "Roberto A Barrero", "Takuro Tamura", "Yumi Yamaguchi-Kabata", "Motohiko Tanino", "Kei Yura", "Satoru Miyazaki", "Kazuho Ikeo", "Keiichi Homma", "Arek Kasprzyk", "Tetsuo Nishikawa", "Mika Hirakawa", "Jean Thierry-Mieg", "Danielle Thierry-Mieg", "Jennifer Ashurst", "Libin Jia", "Mitsuteru Nakao", "Michael A Thomas", "Nicola Mulder", "Youla Karavidopoulou", "Lihua Jin", "Sangsoo Kim", "Tomohiro Yasuda", "Boris Lenhard", "Eric Eveno", "Yoshiyuki Suzuki", "Chisato Yamasaki", "Jun-ichi Takeda", "Craig Gough", "Phillip Hilton", "Yasuyuki Fujii", "Hiroaki Sakai", "Susumu Tanaka", "Clara Amid", "Matthew Bellgard", "Maria de Fatima Bonaldo", "Hidemasa Bono", "Susan K Bromberg", "Anthony J Brookes", "Elspeth Bruford", "Piero Carninci", "Claude Chelala", "Christine Couillault", "Sandro J. de Souza", "Marie-Anne Debily", "Marie-Dominique Devignes", "Inna Dubchak", "Toshinori Endo", "Anne Estreicher", "Eduardo Eyras", "Kaoru Fukami-Kobayashi", "Gopal R. Gopinath", "Esther Graudens", "Yoonsoo Hahn", "Michael Han", "Ze-Guang Han", "Kousuke Hanada", "Hideki Hanaoka", "Erimi Harada", "Katsuyuki Hashimoto", "Ursula Hinz", "Momoki Hirai", "Teruyoshi Hishiki", "Ian Hopkinson", "Sandrine Imbeaud", "Hidetoshi Inoko", "Alexander Kanapin", "Yayoi Kaneko", "Takeya Kasukawa", "Janet Kelso", "Paul Kersey", "Reiko Kikuno", "Kouichi Kimura", "Bernhard Korn", "Vladimir Kuryshev", "Izabela Makalowska", "Takashi Makino", "Shuhei Mano", "Regine Mariage-Samson", "Jun Mashima", "Hideo Matsuda", "Hans-Werner Mewes", "Shinsei Minoshima", "Keiichi Nagai", "Hideki Nagasaki", "Naoki Nagata", "Rajni Nigam", "Osamu Ogasawara", "Osamu Ohara", "Masafumi Ohtsubo", "Norihiro Okada", "Toshihisa Okido", "Satoshi Oota", "Motonori Ota", "Toshio Ota", "Tetsuji Otsuki", "Dominique Piatier-Tonneau", "Annemarie Poustka", "Shuang-Xi Ren", "Naruya Saitou", "Katsunaga Sakai", "Shigetaka Sakamoto", "Ryuichi Sakate", "Ingo Schupp", "Florence Servant", "Stephen Sherry", "Rie Shiba", "Nobuyoshi Shimizu", "Mary Shimoyama", "Andrew J Simpson", "Bento Soares", "Charles Steward", "Makiko Suwa", "Mami Suzuki", "Aiko Takahashi", "Gen Tamiya", "Hiroshi Tanaka", "Todd Taylor", "Joseph D Terwilliger", "Per Unneberg", "Vamsi Veeramachaneni", "Shinya Watanabe", "Laurens Wilming", "Norikazu Yasuda", "Hyang-Sook Yoo", "Marvin Stodolsky", "Wojciech Makalowski", "Mitiko Go", "Kenta Nakai", "Toshihisa Takagi", "Minoru Kanehisa", "Yoshiyuki Sakaki", "John Quackenbush", "Yasushi Okazaki", "Yoshihide Hayashizaki", "Winston Hide", "Ranajit Chakraborty", "Ken Nishikawa", "Hideaki Sugawara", "Yoshio Tateno", "Zhu Chen", "Michio Oishi", "Peter Tonellato", "Rolf Apweiler", "Kousaku Okubo", "Lukas Wagner", "Stefan Wiemann", "Robert L Strausberg", "Takao Isogai", "Charles Auffray", "Nobuo Nomura", "Takashi Gojobori", "Sumio Sugano"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020162.g005", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Manual_Annotation_Flow_Chart_of_ncRNAs/2740441", "title"=>"The Manual Annotation Flow Chart of ncRNAs", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2004-04-20 10:52:07"}

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