Computational Model of Membrane Fission Catalyzed by ESCRT-III
Publication Date
November 20, 2009
Journal
PLOS Computational Biology
Authors
Gur Fabrikant, Suman Lata, James D. Riches, John A. G. Briggs, et al
Volume
5
Issue
11
Pages
e1000575
DOI
http://doi.org/10.1371/journal.pcbi.1000575
Publisher URL
http://journals.plos.org/ploscompbiol/article?id=10.1371%2Fjournal.pcbi.1000575
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/19936052
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773929
Europe PMC
http://europepmc.org/abstract/MED/19936052
Web of Science
000274228500023
Scopus
73449092185
Mendeley
http://www.mendeley.com/research/computational-model-membrane-fission-catalyzed-escrtiii
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Mendeley | Further Information

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CrossRef

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/874916"], "description"=>"<p>The lines correspond to different values of the membrane affinity to the protein dome surface whose values are presented in the insert in mN/m, the total membrane area is .</p>", "links"=>[], "tags"=>["attachment"], "article_id"=>545376, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g004", "stats"=>{"downloads"=>1, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Dependence_of_the_total_system_energy_on_the_attachment_angle_/545376", "title"=>"Dependence of the total system energy on the attachment angle.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:45:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/874706"], "description"=>"<p>A. Formation of the initial bud by CHMP4(Snf7) as suggested in <a href=\"http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000575#pcbi.1000575-Saksena3\" target=\"_blank\">[27]</a>,<a href=\"http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000575#pcbi.1000575-Wollert1\" target=\"_blank\">[29]</a>. B. Self-assembly of CHMP2-CHMP3 nanotube with a dome-like end-cap. C. Fission of the neck and completion of the vesicle formation.</p>", "links"=>[], "tags"=>["membrane", "budding", "fission", "escrt-iii"], "article_id"=>545154, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g001", "stats"=>{"downloads"=>1, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Model_for_membrane_budding_and_fission_by_the_ESCRT_III_sub_complexes_/545154", "title"=>"Model for membrane budding and fission by the ESCRT-III sub-complexes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:44:44"}
  • {"files"=>["https://ndownloader.figshare.com/files/874855"], "description"=>"<p>The lines correspond to different values of the membrane area. (1) ; (2) ; (3) .</p>", "links"=>[], "tags"=>["radius", "attachment"], "article_id"=>545317, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g003", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Dependence_of_the_neck_radius_on_the_attachment_angle_/545317", "title"=>"Dependence of the neck radius on the attachment angle.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:45:37"}
  • {"files"=>["https://ndownloader.figshare.com/files/875124"], "description"=>"<p>The total membrane area, .</p>", "links"=>[], "tags"=>["affinity", "fission", "configuration", "energetically", "modulus", "gaussian"], "article_id"=>545579, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g007", "stats"=>{"downloads"=>2, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_affinity_needed_for_fission_of_the_broad_neck_configuration_to_be_energetically_favorable_depending_on_the_modulus_of_the_Gaussian_curvature_/545579", "title"=>"The affinity needed for fission of the broad neck configuration to be energetically favorable depending on the modulus of the Gaussian curvature.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:47:01"}
  • {"files"=>["https://ndownloader.figshare.com/files/875195"], "description"=>"<p>(A) Electron micrograph showing an ESCRT-III tubule terminating into a hemispherical end-cap structure. (B) The closed end of the tubule after image processing. (C) Extracted edge of the ESCRT-III end-cap. (D) Fit of the extracted edge into the image. (E) Fit of a circle into the edge profile. The methods and experimental details for (A)–(E) are presented in <a href=\"http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000575#pcbi.1000575-Lata2\" target=\"_blank\">[34]</a>. (F) Cross sections of CHMP2A-CHMP3 end-capped tubular structures observed by cryo-electron tomography (see <a href=\"http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1000575#s2b\" target=\"_blank\">Materials and Methods</a>). The images reveal the CHMP2A-CHMP3 protein layer and also the position of MBP proteins fused to the N-terminus of CHMP2A. The scale bar corresponds to a distance of 40nm.</p>", "links"=>[], "tags"=>["escrt-iii"], "article_id"=>545653, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g008", "stats"=>{"downloads"=>5, "page_views"=>32, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Imaging_of_the_ESCRT_III_CHMP2A_CHMP3_assembly_/545653", "title"=>"Imaging of the ESCRT-III (CHMP2A-CHMP3) assembly.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:47:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/874783"], "description"=>"<p>(A) Fore-fission state: - radius of the protein dome surface - the neck radius, - the attachment angle. (B) Post-fission state. The total membrane area .</p>", "links"=>[], "tags"=>["membrane", "attached", "dome", "computed", "configuration"], "article_id"=>545239, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g002", "stats"=>{"downloads"=>0, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Lipid_membrane_attached_to_a_protein_dome_8211_computed_configuration_and_definitions_/545239", "title"=>"Lipid membrane attached to a protein dome – computed configuration and definitions.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:45:11"}
  • {"files"=>["https://ndownloader.figshare.com/files/874976"], "description"=>"<p>The phase boundaries are determined by the characteristic values of the membrane affinity to the protein dome surface, , , and . (A) The total energies of the narrow- and broad- neck configurations are represented by the lines 1 and 2, respectively. (B) The attachment angles in the narrow and broad neck configurations are represented by the lines 1 and 2, respectively, (C) The characteristic affinities depending on the total membrane area . The phase diagrams are divided into four regions corresponding to different regimes of the possible configurations of the system: (I) only broad neck; (II) stable broad neck and quasi-stable narrow neck; (III) stable narrow neck and quasi-stable broad neck; (IV) only narrow neck.</p>", "links"=>[], "tags"=>["diagrams", "describing", "regimes", "configurations", "fore-fission"], "article_id"=>545432, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g005", "stats"=>{"downloads"=>1, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Phase_diagrams_describing_different_regimes_of_the_system_configurations_in_the_fore_fission_state_/545432", "title"=>"Phase diagrams describing different regimes of the system configurations in the fore-fission state.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:46:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/875048"], "description"=>"<p>Dashed lines are the energies of the post-fission state for different values of the modulus of the Gaussian curvature; solid lines (1) and (2) represent, respectively, the energies of the narrow and broad neck configurations of the fore-fission state, .</p>", "links"=>[], "tags"=>["energies", "fore-", "fission", "states"], "article_id"=>545503, "categories"=>["Biophysics"], "users"=>["Gur Fabrikant", "Suman Lata", "James D. Riches", "John A. G. Briggs", "Winfried Weissenhorn", "Michael M. Kozlov"], "doi"=>"https://dx.doi.org/10.1371/journal.pcbi.1000575.g006", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Comparison_of_the_system_energies_in_the_fore_and_post_fission_states_for_determination_of_the_fission_conditions_/545503", "title"=>"Comparison of the system energies in the fore- and post fission states for determination of the fission conditions.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-21 03:46:41"}

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Relative Metric

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