Effects of cis and trans Genetic Ancestry on Gene Expression in African Americans
Publication Date
December 05, 2008
Journal
PLOS Genetics
Authors
Alkes L. Price, Nick Patterson, Dustin C. Hancks, Simon Myers, et al
Volume
4
Issue
12
Pages
e1000294
DOI
http://doi.org/10.1371/journal.pgen.1000294
Publisher URL
http://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1000294
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/19057673
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586034
Europe PMC
http://europepmc.org/abstract/MED/19057673
Web of Science
000263667900009
Scopus
58149159713
Mendeley
http://www.mendeley.com/research/effects-cis-trans-genetic-ancestry-gene-expression-african-americans
Events
Loading … Spinner

CiteULike | Further Information

Mendeley | Further Information

{"title"=>"Effects of cis and trans genetic ancestry on gene expression in African Americans", "type"=>"journal", "authors"=>[{"first_name"=>"Alkes L.", "last_name"=>"Price", "scopus_author_id"=>"10044017100"}, {"first_name"=>"Nick", "last_name"=>"Patterson", "scopus_author_id"=>"7006515330"}, {"first_name"=>"Dustin C.", "last_name"=>"Hancks", "scopus_author_id"=>"15729326600"}, {"first_name"=>"Simon", "last_name"=>"Myers", "scopus_author_id"=>"7402640628"}, {"first_name"=>"David", "last_name"=>"Reich", "scopus_author_id"=>"7102313000"}, {"first_name"=>"Vivian G.", "last_name"=>"Cheung", "scopus_author_id"=>"7005439016"}, {"first_name"=>"Richard S.", "last_name"=>"Spielman", "scopus_author_id"=>"7004451482"}], "year"=>2008, "source"=>"PLoS Genetics", "identifiers"=>{"scopus"=>"2-s2.0-58149159713", "issn"=>"15537390", "pmid"=>"19057673", "pui"=>"354027917", "isbn"=>"1553-7404 (Electronic)\\r1553-7390 (Linking)", "sgr"=>"58149159713", "doi"=>"10.1371/journal.pgen.1000294"}, "id"=>"ad281a76-1c28-3063-bdbc-407dca965ed8", "abstract"=>"Variation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population differences at a large number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that individuals from this population inherit variable proportions of two continental ancestries. We first relate gene expression levels in individual African Americans to their genome-wide proportion of European ancestry. The results provide strong evidence of a genetic contribution to expression differences between European and African populations, validating previous findings. Second, we infer local ancestry (0, 1, or 2 European chromosomes) at each location in the genome and investigate the effects of ancestry proximal to the expressed gene (cis) versus ancestry elsewhere in the genome (trans). Both effects are highly significant, and we estimate that 12+/-3{%} of all heritable variation in human gene expression is due to cis variants.", "link"=>"http://www.mendeley.com/research/effects-cis-trans-genetic-ancestry-gene-expression-african-americans", "reader_count"=>110, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>18, "Researcher"=>35, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>29, "Student > Postgraduate"=>3, "Other"=>4, "Student > Master"=>5, "Student > Bachelor"=>7, "Lecturer"=>1, "Professor"=>7}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>18, "Researcher"=>35, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>29, "Student > Postgraduate"=>3, "Other"=>4, "Student > Master"=>5, "Student > Bachelor"=>7, "Lecturer"=>1, "Professor"=>7}, "reader_count_by_subject_area"=>{"Biochemistry, Genetics and Molecular Biology"=>9, "Mathematics"=>1, "Agricultural and Biological Sciences"=>83, "Medicine and Dentistry"=>11, "Neuroscience"=>1, "Chemistry"=>1, "Computer Science"=>2, "Earth and Planetary Sciences"=>1, "Social Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Neuroscience"=>{"Neuroscience"=>1}, "Chemistry"=>{"Chemistry"=>1}, "Social Sciences"=>{"Social Sciences"=>1}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>83}, "Computer Science"=>{"Computer Science"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>9}, "Mathematics"=>{"Mathematics"=>1}}, "reader_count_by_country"=>{"Austria"=>1, "Turkey"=>1, "Korea (South)"=>1, "United States"=>11, "Uruguay"=>2, "Brazil"=>1, "United Kingdom"=>1, "Mexico"=>1, "Germany"=>1}, "group_count"=>5}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/58149159713"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/58149159713?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=58149159713&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=58149159713&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/58149159713", "dc:identifier"=>"SCOPUS_ID:58149159713", "eid"=>"2-s2.0-58149159713", "dc:title"=>"Effects of cis and trans genetic ancestry on gene expression in African Americans", "dc:creator"=>"Price A.", "prism:publicationName"=>"PLoS Genetics", "prism:issn"=>"15537390", "prism:eIssn"=>"15537404", "prism:volume"=>"4", "prism:issueIdentifier"=>"12", "prism:pageRange"=>nil, "prism:coverDate"=>"2008-12-01", "prism:coverDisplayDate"=>"December 2008", "prism:doi"=>"10.1371/journal.pgen.1000294", "citedby-count"=>"40", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Harvard School of Public Health", "affiliation-city"=>"Boston", "affiliation-country"=>"United States"}, {"@_fa"=>"true", "affilname"=>"Harvard School of Public Health", "affiliation-city"=>"Boston", "affiliation-country"=>"United States"}], "pubmed-id"=>"19057673", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1000294", "source-id"=>"4000151808"}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosgenetics%2Farticle%3Fid%3D10.1371%252Fjournal.pgen.1000294", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"12", "year"=>"2008", "pdf_views"=>"373", "xml_views"=>"11", "html_views"=>"2890"}
  • {"month"=>"1", "year"=>"2009", "pdf_views"=>"93", "xml_views"=>"14", "html_views"=>"453"}
  • {"month"=>"2", "year"=>"2009", "pdf_views"=>"45", "xml_views"=>"2", "html_views"=>"236"}
  • {"month"=>"3", "year"=>"2009", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"229"}
  • {"month"=>"4", "year"=>"2009", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"99"}
  • {"month"=>"5", "year"=>"2009", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"76"}
  • {"month"=>"6", "year"=>"2009", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"142"}
  • {"month"=>"7", "year"=>"2009", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"87"}
  • {"month"=>"8", "year"=>"2009", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"91"}
  • {"month"=>"9", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"102"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"128"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"151"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"76"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"79"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"94"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"3", "html_views"=>"91"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"191"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"86"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"82"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"80"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"97"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"127"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"75"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"64"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"89"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"83"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"79"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"91"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"61"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"72"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"143"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"225"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"190"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"181"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"135"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"157"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"133"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"136"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"64"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"10", "xml_views"=>"5", "html_views"=>"90"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"88"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"113"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"89"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"94"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"9", "xml_views"=>"2", "html_views"=>"226"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"91"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"93"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"78"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"85"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"73"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"74"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"95"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"64"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"69"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"3", "html_views"=>"66"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"56"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"84"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"86"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"106"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"80"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"78"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"52"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"140"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"119"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"155"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"352"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"363"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"182"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"537"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"470"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"853"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"118"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"77"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"48"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"46"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"33"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"71"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"210"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"184"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"41"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"56"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"106"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"107"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"122"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/914262"], "description"=>"<p>We display the top two principal components.</p>", "links"=>[], "tags"=>["components", "aa", "samples", "coriell", "hapmap"], "article_id"=>584712, "categories"=>["Genetics"], "users"=>["Alkes L. Price", "Nick Patterson", "Dustin C. Hancks", "Simon Myers", "David Reich", "Vivian G. Cheung", "Richard S. Spielman"], "doi"=>"https://dx.doi.org/10.1371/journal.pgen.1000294.g001", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Principal_components_analysis_of_AA_samples_from_Coriell_together_with_HapMap_samples_/584712", "title"=>"Principal components analysis of AA samples from Coriell together with HapMap samples.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2008-12-05 01:18:32"}
  • {"files"=>["https://ndownloader.figshare.com/files/914418"], "description"=>"<p>Plots are analogous to <a href=\"http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000294#pgen-1000294-g002\" target=\"_blank\">Figure 2</a> except that genetic (SNP) data were used instead of gene expression data. (A) We plot a random subset of 4,197 markers, for visual comparison to <a href=\"http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000294#pgen-1000294-g002\" target=\"_blank\">Figure 2</a>. (B) We average into bins of 20 markers. The slope of each plot is our estimate 0.96 of the parameter <i>c</i>.</p>", "links"=>[], "tags"=>["differences", "ceu", "yri", "validated", "aa"], "article_id"=>584874, "categories"=>["Genetics"], "users"=>["Alkes L. Price", "Nick Patterson", "Dustin C. Hancks", "Simon Myers", "David Reich", "Vivian G. Cheung", "Richard S. Spielman"], "doi"=>"https://dx.doi.org/10.1371/journal.pgen.1000294.g003", "stats"=>{"downloads"=>2, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Genetic_differences_between_CEU_and_YRI_are_validated_in_AA_samples_/584874", "title"=>"Genetic differences between CEU and YRI are validated in AA samples.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2008-12-05 01:21:14"}
  • {"files"=>["https://ndownloader.figshare.com/files/451910"], "description"=>"<div><p>Variation in gene expression is a fundamental aspect of human phenotypic variation. Several recent studies have analyzed gene expression levels in populations of different continental ancestry and reported population differences at a large number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines, which differ from previously analyzed cell lines in that individuals from this population inherit variable proportions of two continental ancestries. We first relate gene expression levels in individual African Americans to their genome-wide proportion of European ancestry. The results provide strong evidence of a genetic contribution to expression differences between European and African populations, validating previous findings. Second, we infer local ancestry (0, 1, or 2 European chromosomes) at each location in the genome and investigate the effects of ancestry proximal to the expressed gene (<em>cis</em>) versus ancestry elsewhere in the genome (<em>trans</em>). Both effects are highly significant, and we estimate that 12±3% of all heritable variation in human gene expression is due to <em>cis</em> variants.</p></div>", "links"=>[], "tags"=>["effects", "ancestry", "african", "americans"], "article_id"=>149050, "categories"=>["Genetics"], "users"=>["Alkes L. Price", "Nick Patterson", "Dustin C. Hancks", "Simon Myers", "David Reich", "Vivian G. Cheung", "Richard S. Spielman"], "doi"=>"https://dx.doi.org/10.1371/journal.pgen.1000294", "stats"=>{"downloads"=>5, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Effects_of_cis_and_trans_Genetic_Ancestry_on_Gene_Expression_in_African_Americans/149050", "title"=>"Effects of <em>cis</em> and <em>trans</em> Genetic Ancestry on Gene Expression in African Americans", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-12-05 02:30:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/914339"], "description"=>"<p>The y-axis shows the difference in normalized gene expression due to ancestry estimated from AA samples (<i>ã<sub>g</sub></i><sub>,AA</sub>) and the x-axis shows the difference in normalized gene expression due to ancestry estimated from CEU and YRI samples (<i>ã<sub>g</sub></i><sub>,CEU+YRI</sub>) (see <a href=\"http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000294#s2\" target=\"_blank\">Materials and Methods</a> for details of normalization). (A) We plot each of the 4,197 genes separately. (B) For aid in visualization, the 4,197 genes are averaged into bins of 20 genes according to values of <i>ã<sub>g</sub></i><sub>,CEU+YRI</sub>; binning does not affect the slope of the plot. The slope of each plot is our estimate 0.43 of the parameter <i>c</i>.</p>", "links"=>[], "tags"=>["differences", "ceu", "yri", "validated", "aa"], "article_id"=>584791, "categories"=>["Genetics"], "users"=>["Alkes L. Price", "Nick Patterson", "Dustin C. Hancks", "Simon Myers", "David Reich", "Vivian G. Cheung", "Richard S. Spielman"], "doi"=>"https://dx.doi.org/10.1371/journal.pgen.1000294.g002", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Gene_expression_differences_between_CEU_and_YRI_are_validated_in_AA_samples_/584791", "title"=>"Gene expression differences between CEU and YRI are validated in AA samples.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2008-12-05 01:19:51"}

PMC Usage Stats | Further Information

  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"10", "unique-ip"=>"9", "pdf"=>"3", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2010", "pdf"=>"3", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"11", "unique-ip"=>"13", "pdf"=>"4", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"6", "year"=>"2010", "pdf"=>"4", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"6", "unique-ip"=>"9", "pdf"=>"4", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "year"=>"2010", "pdf"=>"4", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "unique-ip"=>"12", "pdf"=>"4", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"29", "year"=>"2010", "pdf"=>"1", "unique-ip"=>"17", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"29", "unique-ip"=>"18", "pdf"=>"6", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"11", "year"=>"2010", "pdf"=>"5", "unique-ip"=>"10", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"10", "unique-ip"=>"11", "pdf"=>"5", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2010", "pdf"=>"2", "unique-ip"=>"2", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "unique-ip"=>"6", "pdf"=>"5", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"5", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "unique-ip"=>"5", "pdf"=>"0", "year"=>"2011", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"3", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"7", "unique-ip"=>"7", "pdf"=>"6", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"0", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"1", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "unique-ip"=>"7", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"6", "year"=>"2011", "pdf"=>"1", "unique-ip"=>"5", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"6", "pdf"=>"3", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "year"=>"2011", "pdf"=>"2", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"2", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"6", "pdf"=>"1", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2011", "pdf"=>"1", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "year"=>"2012", "pdf"=>"2", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"1", "pdf"=>"1", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2012", "pdf"=>"4", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"3", "pdf"=>"2", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"21", "unique-ip"=>"24", "pdf"=>"11", "year"=>"2008", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"51", "year"=>"2009", "pdf"=>"21", "unique-ip"=>"45", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"37", "unique-ip"=>"33", "pdf"=>"23", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"20", "year"=>"2009", "pdf"=>"11", "unique-ip"=>"20", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"16", "unique-ip"=>"17", "pdf"=>"4", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"22", "year"=>"2009", "pdf"=>"7", "unique-ip"=>"20", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"13", "unique-ip"=>"14", "pdf"=>"5", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"9", "year"=>"2009", "pdf"=>"6", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"23", "unique-ip"=>"14", "pdf"=>"12", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "year"=>"2009", "pdf"=>"6", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"5", "unique-ip"=>"7", "pdf"=>"4", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"17", "year"=>"2009", "pdf"=>"10", "unique-ip"=>"17", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"11", "unique-ip"=>"10", "pdf"=>"1", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"0", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"1", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"6", "full-text"=>"15", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"15", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"6", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"20", "full-text"=>"49", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"7", "cited-by"=>"6", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"3", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"3", "full-text"=>"11", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"7", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"10", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}

Relative Metric

{"start_date"=>"2008-01-01T00:00:00Z", "end_date"=>"2008-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[324, 674, 863, 1015, 1146, 1259, 1360, 1452, 1540, 1621, 1704, 1776, 1843, 1905, 1968, 2029, 2097, 2162, 2233, 2289, 2352, 2412, 2476, 2538, 2601, 2655, 2714, 2777, 2841, 2894, 2946, 2998, 3047, 3103, 3151, 3201, 3258, 3317, 3369, 3424, 3471, 3521, 3583, 3625, 3687, 3743, 3788, 3838, 3896, 3953, 4015, 4075, 4148, 4201, 4275, 4347, 4420, 4486, 4535, 4592, 4660, 4731, 4792, 4845, 4901, 4971, 5027, 5089, 5148, 5200, 5261, 5318, 5374]}, {"subject_area"=>"/Biology and life sciences/Cell biology", "average_usage"=>[303, 628, 827, 976, 1105, 1222, 1321, 1406, 1482, 1564, 1639, 1713, 1784, 1851, 1915, 1966, 2020, 2080, 2138, 2203, 2258, 2315, 2379, 2437, 2492, 2556, 2613, 2670, 2726, 2785, 2834, 2886, 2948, 2988, 3037, 3089, 3140, 3179, 3236, 3283, 3340, 3390, 3438, 3487, 3541, 3586, 3642, 3707, 3754, 3805, 3853, 3897, 3956, 4016, 4081, 4152, 4218, 4258, 4319, 4378, 4442, 4487, 4536, 4589, 4635, 4689, 4754, 4807, 4863, 4920, 4982, 5042, 5094]}, {"subject_area"=>"/Biology and life sciences/Genetics", "average_usage"=>[329, 686, 873, 1009, 1130, 1239, 1337, 1426, 1509, 1585, 1667, 1746, 1816, 1880, 1937, 1999, 2058, 2120, 2179, 2245, 2311, 2374, 2437, 2511, 2565, 2616, 2671, 2723, 2783, 2844, 2902, 2958, 3017, 3056, 3104, 3169, 3206, 3249, 3298, 3354, 3428, 3479, 3526, 3579, 3628, 3679, 3727, 3771, 3819, 3865, 3927, 4006, 4075, 4116, 4164, 4250, 4323, 4380, 4436, 4492, 4547, 4599, 4652, 4708, 4761, 4811, 4889, 4966, 5025, 5071, 5134, 5186, 5258]}, {"subject_area"=>"/Biology and life sciences/Molecular biology", "average_usage"=>[328, 663, 852, 1015, 1147, 1265, 1369, 1468, 1557, 1626, 1696, 1763, 1830, 1909, 1970, 2025, 2105, 2189, 2263, 2309, 2368, 2432, 2502, 2569, 2629, 2709, 2780, 2835, 2900, 2949, 2998, 3064, 3110, 3179, 3235, 3286, 3334, 3390, 3447, 3501, 3550, 3606, 3663, 3704, 3751, 3810, 3858, 3929, 3990, 4058, 4112, 4190, 4252, 4322, 4399, 4471, 4539, 4620, 4692, 4750, 4833, 4898, 4945, 5006, 5058, 5114, 5155, 5210, 5262, 5319, 5386, 5445, 5493]}, {"subject_area"=>"/Biology and life sciences/Population biology", "average_usage"=>[349, 704, 911, 1075, 1165, 1272, 1340, 1452, 1534, 1604, 1672, 1722, 1787, 1845, 1902, 1974, 2047, 2114, 2188, 2269, 2330, 2396, 2463, 2546, 2617, 2666, 2725, 2778, 2853, 2903, 2942, 2974, 3017, 3052, 3090, 3129, 3201, 3249, 3290, 3339, 3379, 3433, 3507, 3565, 3602, 3651, 3732, 3788, 3850, 3906, 3940, 4005, 4055, 4103, 4157, 4241, 4356, 4395, 4486, 4530, 4596, 4669, 4708, 4772, 4820, 4869, 4902, 4943, 4989, 5037, 5086, 5145, 5176]}, {"subject_area"=>"/People and places", "average_usage"=>[376, 765, 965, 1137, 1264, 1357, 1454, 1568, 1659, 1751, 1833, 1905, 1979, 2059, 2132, 2187, 2267, 2344, 2399, 2463, 2517, 2586, 2645, 2716, 2834, 2894, 3003, 3079, 3152, 3226, 3290, 3339, 3407, 3455, 3530, 3612, 3691, 3755, 3794, 3824, 3876, 3937, 3997, 4052, 4129, 4211, 4295, 4334, 4367, 4428, 4488, 4527, 4563, 4639, 4717, 4795, 4853, 4928, 4993, 5108, 5167, 5235, 5316, 5376, 5415, 5479, 5543, 5619, 5668, 5735, 5797, 5896, 5961]}, {"subject_area"=>"/People and places/Population groupings", "average_usage"=>[388, 790, 999, 1162, 1312, 1449, 1566, 1650, 1743, 1818, 1897, 1992, 2060, 2130, 2212, 2295, 2363, 2434, 2498, 2561, 2632, 2695, 2779, 2870, 2946, 3007, 3053, 3149, 3234, 3307, 3366, 3396, 3453, 3519, 3618, 3696, 3781, 3884, 3972, 4051, 4119, 4173, 4255, 4293, 4355, 4428, 4515, 4603, 4645, 4710, 4778, 4846, 4888, 4934, 4992, 5048, 5089, 5148, 5200, 5283, 5373, 5415, 5436, 5460, 5531, 5610, 5694, 5742, 5807, 5865, 5921, 5986, 6094]}]}

F1000Prime | Further Information

Loading … Spinner
There are currently no alerts