The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
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{"title"=>"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration", "type"=>"generic", "authors"=>[{"first_name"=>"Alessandro", "last_name"=>"Liberati", "scopus_author_id"=>"7005650746"}, {"first_name"=>"Douglas G.", "last_name"=>"Altman", "scopus_author_id"=>"7201380947"}, {"first_name"=>"Jennifer", "last_name"=>"Tetzlaff", "scopus_author_id"=>"16069577300"}, {"first_name"=>"Cynthia", "last_name"=>"Mulrow", "scopus_author_id"=>"7005751787"}, {"first_name"=>"Peter C.", "last_name"=>"Gøtzsche", "scopus_author_id"=>"35233694400"}, {"first_name"=>"John P.A.", "last_name"=>"Ioannidis", "scopus_author_id"=>"35377033000"}, {"first_name"=>"Mike", "last_name"=>"Clarke", "scopus_author_id"=>"55559031600"}, {"first_name"=>"P. J.", "last_name"=>"Devereaux", "scopus_author_id"=>"7004238603"}, {"first_name"=>"Jos", "last_name"=>"Kleijnen", "scopus_author_id"=>"24344322300"}, {"first_name"=>"David", "last_name"=>"Moher", "scopus_author_id"=>"7005443800"}], "year"=>2009, "source"=>"PLoS Medicine", "identifiers"=>{"pmid"=>"19621070", "doi"=>"10.1371/journal.pmed.1000100", "sgr"=>"68049137869", "arxiv"=>"arXiv:1011.1669v3", "isbn"=>"2006062298", "scopus"=>"2-s2.0-68049137869", "issn"=>"15491277", "pui"=>"355033308"}, "id"=>"d081cd9f-ac94-38da-8725-450294565767", "abstract"=>"Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users.Since the development of the QUOROM (QUality Of Reporting Of Meta-analysis) Statement--a reporting guideline published in 1999--there have been several conceptual, methodological, and practical advances regarding the conduct and reporting of systematic reviews and meta-analyses. Also, reviews of published systematic reviews have found that key information about these studies is often poorly reported. Realizing these issues, an international group that included experienced authors and methodologists developed PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) as an evolution of the original QUOROM guideline for systematic reviews and meta-analyses of evaluations of health care interventions.The PRISMA Statement consists of a 27-item checklist and a four-phase flow diagram. The checklist includes items deemed essential for transparent reporting of a systematic review. In this Explanation and Elaboration document, we explain the meaning and rationale for each checklist item. For each item, we include an example of good reporting and, where possible, references to relevant empirical studies and methodological literature. The PRISMA Statement, this document, and the associated Web site (http://www.prisma-statement.org/) should be helpful resources to improve reporting of systematic reviews and meta-analyses.", "link"=>"http://www.mendeley.com/research/prisma-statement-reporting-systematic-reviews-metaanalyses-studies-evaluate-health-care-intervention-72", "reader_count"=>2554, "reader_count_by_academic_status"=>{"Unspecified"=>82, "Professor > Associate Professor"=>108, "Librarian"=>37, "Student > Doctoral Student"=>174, "Researcher"=>345, "Student > Ph. D. Student"=>483, "Student > Postgraduate"=>173, "Student > Master"=>592, "Other"=>150, "Student > Bachelor"=>267, "Lecturer"=>48, "Lecturer > Senior Lecturer"=>19, "Professor"=>76}, "reader_count_by_user_role"=>{"Unspecified"=>82, "Professor > Associate Professor"=>108, "Librarian"=>37, "Student > Doctoral Student"=>174, "Researcher"=>345, "Student > Ph. D. 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  • {"files"=>["https://ndownloader.figshare.com/files/891114"], "description"=>"<p>Checklist of items to include when reporting a systematic review (with or without meta-analysis).</p>", "links"=>[], "tags"=>["items", "systematic"], "article_id"=>561568, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.t001", "stats"=>{"downloads"=>0, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Checklist_of_items_to_include_when_reporting_a_systematic_review_with_or_without_meta_analysis_/561568", "title"=>"Checklist of items to include when reporting a systematic review (with or without meta-analysis).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-07-21 00:26:08"}
  • {"files"=>["https://ndownloader.figshare.com/files/890756"], "description"=>"<p>DDW, Digestive Disease Week; UEGW, United European Gastroenterology Week. Reproduced with permission from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-Fuccio1\" target=\"_blank\">[130]</a>.</p>", "links"=>[], "tags"=>["diagram"], "article_id"=>561210, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.g002", "stats"=>{"downloads"=>3, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Figure_Example_flow_diagram_of_study_selection_/561210", "title"=>"Example Figure: Example flow diagram of study selection.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-07-21 00:20:10"}
  • {"files"=>["https://ndownloader.figshare.com/files/891034"], "description"=>"<p>ED, emergency department; GE, gastroenteritis; IV, intravenous; PO, by mouth.</p><p>Adapted from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-DeCamp1\" target=\"_blank\">[135]</a>.</p>", "links"=>[], "tags"=>["included", "studies", "evaluating", "efficacy", "antiemetic", "agents", "acute"], "article_id"=>561479, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.t002", "stats"=>{"downloads"=>0, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Table_Summary_of_included_studies_evaluating_the_efficacy_of_antiemetic_agents_in_acute_gastroenteritis_/561479", "title"=>"Example Table: Summary of included studies evaluating the efficacy of antiemetic agents in acute gastroenteritis.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-07-21 00:24:39"}
  • {"files"=>["https://ndownloader.figshare.com/files/891074"], "description"=>"<p>RCT, randomized controlled trial.</p><p>Adapted from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-Devereaux1\" target=\"_blank\">[96]</a>.</p>", "links"=>[], "tags"=>["measures", "randomized", "controlled", "trials", "failed", "fulfill", "markers"], "article_id"=>561519, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.t003", "stats"=>{"downloads"=>1, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Table_Quality_measures_of_the_randomized_controlled_trials_that_failed_to_fulfill_any_one_of_six_markers_of_validity_/561519", "title"=>"Example Table: Quality measures of the randomized controlled trials that failed to fulfill any one of six markers of validity.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-07-21 00:25:19"}
  • {"files"=>["https://ndownloader.figshare.com/files/890886"], "description"=>"<p>CI, confidence interval. Reproduced with permission from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-Skalsky1\" target=\"_blank\">[137]</a>.</p>", "links"=>[], "tags"=>["assigned", "regimen", "tetracycline-rifampicin"], "article_id"=>561340, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.g003", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Figure_Overall_failure_defined_as_failure_of_assigned_regimen_or_relapse_with_tetracycline_rifampicin_versus_tetracycline_streptomycin_/561340", "title"=>"Example Figure: Overall failure (defined as failure of assigned regimen or relapse) with tetracycline-rifampicin versus tetracycline-streptomycin.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-07-21 00:22:20"}
  • {"files"=>["https://ndownloader.figshare.com/files/441256", "https://ndownloader.figshare.com/files/441283"], "description"=>"<div><p>Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safety of health care interventions accurately and reliably. The clarity and transparency of these reports, however, is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, and other users.</p><p>Since the development of the QUOROM (<em>QU</em>ality <em>O</em>f <em>R</em>eporting <em>O</em>f <em>M</em>eta-analysis) Statement—a reporting guideline published in 1999—there have been several conceptual, methodological, and practical advances regarding the conduct and reporting of systematic reviews and meta-analyses. Also, reviews of published systematic reviews have found that key information about these studies is often poorly reported. Realizing these issues, an international group that included experienced authors and methodologists developed PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) as an evolution of the original QUOROM guideline for systematic reviews and meta-analyses of evaluations of health care interventions.</p><p>The PRISMA Statement consists of a 27-item checklist and a four-phase flow diagram. The checklist includes items deemed essential for transparent reporting of a systematic review. In this Explanation and Elaboration document, we explain the meaning and rationale for each checklist item. For each item, we include an example of good reporting and, where possible, references to relevant empirical studies and methodological literature. The PRISMA Statement, this document, and the associated Web site (<a href=\"http://www.prisma-statement.org/\">http://www.prisma-statement.org/</a>) should be helpful resources to improve reporting of systematic reviews and meta-analyses.</p></div>", "links"=>[], "tags"=>["prisma", "systematic", "reviews", "meta-analyses", "studies", "elaboration"], "article_id"=>146969, "categories"=>["Cancer"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>["https://dx.doi.org/10.1371/journal.pmed.1000100.s001", "https://dx.doi.org/10.1371/journal.pmed.1000100.s002"], "stats"=>{"downloads"=>20, "page_views"=>23, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_PRISMA_Statement_for_Reporting_Systematic_Reviews_and_Meta_Analyses_of_Studies_That_Evaluate_Health_Care_Interventions_Explanation_and_Elaboration/146969", "title"=>"The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2009-07-21 01:56:09"}
  • {"files"=>["https://ndownloader.figshare.com/files/891161"], "description"=>"<p>NSAID, non-steroidal anti-inflammatory drug.</p><p>Adapted from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-Pakos1\" target=\"_blank\">[136]</a>.</p>", "links"=>[], "tags"=>["heterotopic", "ossification", "trials", "comparing", "radiotherapy", "non-steroidal", "anti-inflammatory", "drugs", "procedures"], "article_id"=>561610, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.t004", "stats"=>{"downloads"=>1, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Table_Heterotopic_ossification_in_trials_comparing_radiotherapy_to_non_steroidal_anti_inflammatory_drugs_after_major_hip_procedures_and_fractures_/561610", "title"=>"Example Table: Heterotopic ossification in trials comparing radiotherapy to non-steroidal anti-inflammatory drugs after major hip procedures and fractures.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-07-21 00:26:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/890676"], "description"=>"<p>Flow of information through the different phases of a systematic review.</p>", "links"=>[], "tags"=>["phases", "systematic"], "article_id"=>561125, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.g001", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Flow_of_information_through_the_different_phases_of_a_systematic_review_/561125", "title"=>"Flow of information through the different phases of a systematic review.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-07-21 00:18:45"}
  • {"files"=>["https://ndownloader.figshare.com/files/890959"], "description"=>"<p>SE, standard error. Adapted from <a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000100#pmed.1000100-Appleton1\" target=\"_blank\">[146]</a>, with permission.</p>", "links"=>[], "tags"=>["funnel"], "article_id"=>561409, "categories"=>["Infectious Diseases"], "users"=>["Alessandro Liberati", "Douglas G. Altman", "Jennifer Tetzlaff", "Cynthia Mulrow", "Peter C. Gøtzsche", "John P. A. Ioannidis", "Mike Clarke", "P. J. Devereaux", "Jos Kleijnen", "David Moher"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.1000100.g004", "stats"=>{"downloads"=>3, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Example_Figure_Example_of_a_funnel_plot_showing_evidence_of_considerable_asymmetry_/561409", "title"=>"Example Figure: Example of a funnel plot showing evidence of considerable asymmetry.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-07-21 00:23:29"}

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