Genital Tract Sequestration of SIV following Acute Infection
Publication Date
February 17, 2011
Journal
PLOS Pathogens
Authors
James B. Whitney, Peter T. Hraber, Corinne Luedemann, Elena E. Giorgi, et al
Volume
7
Issue
2
Pages
e1001293
DOI
http://doi.org/10.1371/journal.ppat.1001293
Publisher URL
http://journals.plos.org/plospathogens/article?id=10.1371%2Fjournal.ppat.1001293
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/21379569
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040679
Europe PMC
http://europepmc.org/abstract/MED/21379569
Web of Science
000287698200031
Scopus
79952232531
Mendeley
http://www.mendeley.com/research/genital-tract-sequestration-siv-following-acute-infection
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Genital tract sequestration of SIV following acute infection", "type"=>"journal", "authors"=>[{"first_name"=>"James B.", "last_name"=>"Whitney", "scopus_author_id"=>"7201891754"}, {"first_name"=>"Peter T.", "last_name"=>"Hraber", "scopus_author_id"=>"6602359749"}, {"first_name"=>"Corinne", "last_name"=>"Luedemann", "scopus_author_id"=>"56430941700"}, {"first_name"=>"Elena E.", "last_name"=>"Giorgi", "scopus_author_id"=>"13905209100"}, {"first_name"=>"Marcus G.", "last_name"=>"Daniels", "scopus_author_id"=>"7201966529"}, {"first_name"=>"Tanmoy", "last_name"=>"Bhattacharya", "scopus_author_id"=>"7006308075"}, {"first_name"=>"Srinivas S.", "last_name"=>"Rao", "scopus_author_id"=>"8530503200"}, {"first_name"=>"John R.", "last_name"=>"Mascola", "scopus_author_id"=>"7005343486"}, {"first_name"=>"Gary J.", "last_name"=>"Nabel", "scopus_author_id"=>"7103259116"}, {"first_name"=>"Bette T.", "last_name"=>"Korber", "scopus_author_id"=>"19335057200"}, {"first_name"=>"Norman L.", "last_name"=>"Letvin", "scopus_author_id"=>"35392680100"}], "year"=>2011, "source"=>"PLoS Pathogens", "identifiers"=>{"isbn"=>"1553-7374 (Electronic)\\r1553-7366 (Linking)", "scopus"=>"2-s2.0-79952232531", "doi"=>"10.1371/journal.ppat.1001293", "issn"=>"15537366", "pui"=>"361364829", "pmid"=>"21379569", "sgr"=>"79952232531"}, "id"=>"29333d84-e798-3334-b380-63ef66be7fa1", "abstract"=>"We characterized the evolution of simian immunodeficiency virus (SIV) in the male genital tract by examining blood- and semen-associated virus from experimentally and sham vaccinated rhesus monkeys during primary infection. At the time of peak virus replication, SIV sequences were intermixed between the blood and semen supporting a scenario of high-level virus \"spillover\" into the male genital tract. However, at the time of virus set point, compartmentalization was apparent in 4 of 7 evaluated monkeys, likely as a consequence of restricted virus gene flow between anatomic compartments after the resolution of primary viremia. These findings suggest that SIV replication in the male genital tract evolves to compartmentalization after peak viremia resolves.", "link"=>"http://www.mendeley.com/research/genital-tract-sequestration-siv-following-acute-infection", "reader_count"=>21, "reader_count_by_academic_status"=>{"Researcher"=>8, "Student > Ph. D. Student"=>5, "Student > Master"=>2, "Other"=>1, "Student > Bachelor"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>2}, "reader_count_by_user_role"=>{"Researcher"=>8, "Student > Ph. D. Student"=>5, "Student > Master"=>2, "Other"=>1, "Student > Bachelor"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>2}, "reader_count_by_subject_area"=>{"Biochemistry, Genetics and Molecular Biology"=>1, "Mathematics"=>1, "Agricultural and Biological Sciences"=>13, "Medicine and Dentistry"=>5, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>5}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>13}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Mathematics"=>{"Mathematics"=>1}}, "reader_count_by_country"=>{"South Africa"=>2, "Mexico"=>1}, "group_count"=>0}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79952232531"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79952232531?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952232531&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=79952232531&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/79952232531", "dc:identifier"=>"SCOPUS_ID:79952232531", "eid"=>"2-s2.0-79952232531", "dc:title"=>"Genital tract sequestration of SIV following acute infection", "dc:creator"=>"Whitney J.", "prism:publicationName"=>"PLoS Pathogens", "prism:issn"=>"15537366", "prism:eIssn"=>"15537374", "prism:volume"=>"7", "prism:issueIdentifier"=>"2", "prism:pageRange"=>nil, "prism:coverDate"=>"2011-02-01", "prism:coverDisplayDate"=>"February 2011", "prism:doi"=>"10.1371/journal.ppat.1001293", "citedby-count"=>"11", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Beth Israel Deaconess Medical Center", "affiliation-city"=>"Boston", "affiliation-country"=>"United States"}, {"@_fa"=>"true", "affilname"=>"Harvard Medical School", "affiliation-city"=>"Boston", "affiliation-country"=>"United States"}], "pubmed-id"=>"21379569", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1001293", "source-id"=>"4000151809"}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplospathogens%2Farticle%3Fid%3D10.1371%252Fjournal.ppat.1001293", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"86", "xml_views"=>"5", "html_views"=>"313"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"63", "xml_views"=>"5", "html_views"=>"225"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"80"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"35"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"19"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"46"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"5", "html_views"=>"29"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"19"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"19"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"20"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"12", "html_views"=>"22"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"175"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"48"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"78"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"97"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"99"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"2", "html_views"=>"98"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"101"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"1", "xml_views"=>"3", "html_views"=>"37"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"68"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"101"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"91"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"99"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"61"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"57"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"31"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"4"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"7"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"9"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"10"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"3", "html_views"=>"10"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"11"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/398866", "https://ndownloader.figshare.com/files/398907"], "description"=>"<div><p>We characterized the evolution of simian immunodeficiency virus (SIV) in the male genital tract by examining blood- and semen-associated virus from experimentally and sham vaccinated rhesus monkeys during primary infection. At the time of peak virus replication, SIV sequences were intermixed between the blood and semen supporting a scenario of high-level virus “spillover” into the male genital tract. However, at the time of virus set point, compartmentalization was apparent in 4 of 7 evaluated monkeys, likely as a consequence of restricted virus gene flow between anatomic compartments after the resolution of primary viremia. These findings suggest that SIV replication in the male genital tract evolves to compartmentalization after peak viremia resolves.</p></div>", "links"=>[], "tags"=>["genital", "tract", "sequestration", "siv", "acute"], "article_id"=>138786, "categories"=>["Medicine", "Cancer"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.s001", "https://dx.doi.org/10.1371/journal.ppat.1001293.s002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Genital_Tract_Sequestration_of_SIV_following_Acute_Infection/138786", "title"=>"Genital Tract Sequestration of SIV following Acute Infection", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2011-02-17 02:26:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/797626"], "description"=>"<p>Neighbor-joining trees from vaccinated monkeys (<b>A</b>) AX93, (<b>B</b>) AY47 and control monkeys (<b>C</b>) CK7J and (<b>D</b>) CM8X 2 weeks after challenge with a sequence-defined SIVmac251 challenge stock (stock sequences denoted in black).</p>", "links"=>[], "tags"=>["blood-", "semen-derived", "sequences", "siv"], "article_id"=>467979, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Intermixing_of_blood_and_semen_derived_env_sequences_during_peak_SIV_replication_/467979", "title"=>"Intermixing of blood- and semen-derived <i>env</i> sequences during peak SIV replication.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:12:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/797746"], "description"=>"<p>NJ tree from control animal AX89, 2 weeks after challenge using a sequence-defined SIVmac251 stock (denoted in black).</p>", "links"=>[], "tags"=>["blood-", "semen-derived", "sequences", "siv", "replication"], "article_id"=>468100, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Compartmentalization_of_blood_and_semen_derived_env_sequences_during_peak_SIV_replication_in_monkey_AX89_/468100", "title"=>"Compartmentalization of blood- and semen-derived <i>env</i> sequences during peak SIV replication in monkey AX89.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:15:00"}
  • {"files"=>["https://ndownloader.figshare.com/files/797865"], "description"=>"<p>(<b>A</b>) Semen virus DNA levels in the control and Gag-Pol vaccinated monkeys 14 days after virus challenge. The comparisons of the data from the Gag-Pol vaccinated and control groups were analyzed using the Mann-Whitney non-parametric T-test. The absolute number of SIV <i>gag</i> DNA copies was calculated as described previously <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1001293#ppat.1001293-Whitney2\" target=\"_blank\">[44]</a>, and is shown as log-transformed copies per 1×10<sup>5</sup> semen-associated cells. (<b>B</b>) Phylogeny of SIV <i>env</i> in monkey CK7J, 14 days after virus challenge with blood plasma virus, semen plasma and semen cell-associated virus indicated.</p>", "links"=>[], "tags"=>["siv", "semen-associated"], "article_id"=>468225, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Source_of_SIV_in_the_semen_associated_cell_fraction_/468225", "title"=>"Source of SIV in the semen-associated cell fraction.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:17:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/798001"], "description"=>"<p>By 16 weeks after SIV challenge, compartmentalization of virus in semen and blood was apparent in 4 of 7 animals on the basis of tree topology and the SM test. NJ trees of SGA-derived <i>env</i> amplicons for compartmentalized monkeys (<b>A</b>) C179, (<b>B</b>) AX93 (<b>C</b>) AX89, and (<b>D</b>) AY89 are shown. Note that monkey AX89 is a control monkey and C179, AX93 and AY89 are vaccinated animals.</p>", "links"=>[], "tags"=>["diversification", "siv"], "article_id"=>468364, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Anatomic_sequestration_and_diversification_of_SIV_during_set_point_virus_replication_/468364", "title"=>"Anatomic sequestration, and diversification of SIV during set point virus replication.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:19:24"}
  • {"files"=>["https://ndownloader.figshare.com/files/798089"], "description"=>"<p>Diagrams indicating the positions of predicted recombination breakpoints in compartmentalized monkeys AX89, AX93 and C179 and non-compartmentalized monkey, DA2D. Recombination effects were determined by G.A.R.D. analysis as described. Breakpoint partitions are indicated as vertical lines between inverted triangles. SIV <i>env</i> regions with significant compartmentalization as determined by the partitioned SM test on partitioned sequences, <b>P<0.0002</b> are highlighted in red boxes.</p>", "links"=>[], "tags"=>["recombination", "obscures", "compartmentalization", "siv"], "article_id"=>468451, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g005"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Virus_recombination_obscures_compartmentalization_of_SIV_env_sequences_/468451", "title"=>"Virus recombination obscures compartmentalization of SIV <i>env</i> sequences.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:20:51"}
  • {"files"=>["https://ndownloader.figshare.com/files/798185"], "description"=>"<p>SM migration events were plotted directly onto NJ trees for the 4 monkeys characterized 16 weeks after SIV challenge. Unrestricted viral gene flow between the blood and semen in monkeys C171 (<b>A</b>) and DA2D (<b>B</b>), and restricted gene flow in compartmentalized monkeys AY89 (<b>C</b>) and AX93 (<b>D</b>).</p>", "links"=>[], "tags"=>["semen", "temporally"], "article_id"=>468548, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g006"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Restricted_gene_flow_between_the_blood_and_semen_is_temporally_associated_with_compartmentalization_/468548", "title"=>"Restricted gene flow between the blood and semen is temporally associated with compartmentalization.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:22:28"}
  • {"files"=>["https://ndownloader.figshare.com/files/798282"], "description"=>"<p>Cell-associated SIV trafficking into the male genital tract during peak and set point SIV infection. The comparisons of the data from the Gag-Pol vaccinated and control groups were analyzed using the Mann-Whitney non-parametric U-test. The absolute number of SIV <i>gag</i> DNA copies was calculated as described previously, and is shown as log-transformed copies per 1×10<sup>5</sup> semen-associated cells. (<b>A</b>). Association and threshold effect between levels in blood plasma and seminal plasma from both vaccinated and control monkeys (<b>B</b>). Adapted from Whitney et al. <a href=\"http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1001293#ppat.1001293-Whitney2\" target=\"_blank\">[44]</a>.</p>", "links"=>[], "tags"=>["threshold-effect", "siv", "rna", "levels"], "article_id"=>468645, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.g007"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Association_and_threshold_effect_between_SIV_DNA_and_RNA_levels_in_blood_and_semen_/468645", "title"=>"Association and threshold-effect between SIV DNA, and RNA levels in blood and semen.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-17 02:24:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/798361"], "description"=>"<p>SIV <i>env</i> clones from control (<b>C</b>) and vaccinated (<b>V</b>) monkeys were amplified by SGA from semen and blood plasma 2 or 16 weeks after infection with a sequence-defined SIVmac251 stock. Shown are the number of sequence clones in blood and semen, the number of phylogenetically informative sites, and the Mean Pairwise Distance from the challenge stock.</p>", "links"=>[], "tags"=>["sequences"], "article_id"=>468726, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Quantity_and_diversity_of_sequences_obtained_per_sample_/468726", "title"=>"Quantity and diversity of sequences obtained per sample.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-17 02:25:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/798409"], "description"=>"<p>SIV <i>env</i> clones from control (<b>C</b>) and vaccinated (<b>V</b>) monkeys were amplified by SGA from semen and blood plasma 16 weeks after infection with a sequence-defined SIVmac251 stock. Shown are the number of clones per compartment (<b>n</b>), the number of Slatkin-Maddison migration events (<b>s</b>), and the number of permuted replicates having at most <b>s</b> migrations (<b>N</b>(<b>s'≤s</b>)) with associated P values from 10,000 replicate permutations, and P values from trees normalized by eliminating multiple copies of identical sequences (<b>P<sub>n</sub></b>).</p>", "links"=>[], "tags"=>["compartmentalization"], "article_id"=>468769, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.t003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_SIV_genetic_compartmentalization_at_virus_set_point_/468769", "title"=>"SIV genetic compartmentalization at virus set point.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-17 02:26:09"}
  • {"files"=>["https://ndownloader.figshare.com/files/798443"], "description"=>"<p>SIV <i>env</i> clones from control (<b>C</b>) and vaccinated (<b>V</b>) monkeys were amplified by SGA from semen and blood plasma 2 weeks after infection with a sequence-defined SIVmac251 stock. Shown are the number of clones per compartment (<b>n</b>), the number of Slatkin-Maddison migration events (<b>s</b>), and the number of permuted replicates having at most <b>s</b> migrations (<b>N(s'≤s)</b>) with associated P values (<b>P</b>) from 10,000 replicate permutations.</p>", "links"=>[], "tags"=>["compartmentalization"], "article_id"=>468807, "categories"=>["Medicine", "Infectious Diseases", "Virology"], "users"=>["James B. Whitney", "Peter T. Hraber", "Corinne Luedemann", "Elena E. Giorgi", "Marcus G. Daniels", "Tanmoy Bhattacharya", "Srinivas S. Rao", "John R. Mascola", "Gary J. Nabel", "Bette T. Korber", "Norman L. Letvin"], "doi"=>["https://dx.doi.org/10.1371/journal.ppat.1001293.t002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_SIV_genetic_compartmentalization_at_peak_virus_replication_/468807", "title"=>"SIV genetic compartmentalization at peak virus replication.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-17 02:26:47"}

PMC Usage Stats | Further Information

  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"7", "full-text"=>"18", "unique-ip"=>"26", "pdf"=>"12", "year"=>"2011", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"11", "year"=>"2011", "pdf"=>"10", "unique-ip"=>"16", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"9", "unique-ip"=>"13", "pdf"=>"5", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"9", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"9", "pdf"=>"3", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"9", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"10", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"5", "pdf"=>"2", "year"=>"2011", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"9", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"4", "pdf"=>"1", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "year"=>"2011", "pdf"=>"1", "unique-ip"=>"7", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"4", "pdf"=>"2", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"9", "year"=>"2012", "pdf"=>"6", "unique-ip"=>"10", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "unique-ip"=>"11", "pdf"=>"3", "year"=>"2012", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "year"=>"2012", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "unique-ip"=>"9", "pdf"=>"7", "year"=>"2012", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"1", "unique-ip"=>"3", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"2", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"2", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"1", "pdf"=>"1", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"1", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"12", "full-text"=>"5", "pdf"=>"4", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"2", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"27", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"2", "cited-by"=>"2", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}

Relative Metric

{"start_date"=>"2011-01-01T00:00:00Z", "end_date"=>"2011-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[304, 568, 702, 818, 927, 1027, 1118, 1206, 1285, 1357, 1427, 1500, 1564, 1636, 1705, 1773, 1840, 1909, 1974, 2039, 2106, 2170, 2234, 2296, 2358, 2423, 2484, 2546, 2606, 2673, 2734, 2795, 2857, 2921, 2984, 3046, 3100]}, {"subject_area"=>"/Biology and life sciences/Anatomy and physiology", "average_usage"=>[298, 559, 690, 805, 916, 1018, 1115, 1201, 1283, 1356, 1425, 1498, 1565, 1635, 1703, 1767, 1835, 1902, 1962, 2027, 2089, 2150, 2210, 2265]}, {"subject_area"=>"/Biology and life sciences/Organisms", "average_usage"=>[316, 571, 699, 812, 915, 1008, 1095, 1180, 1255, 1319, 1393, 1461, 1528, 1595, 1662, 1729, 1802, 1868, 1937, 1997, 2062, 2130, 2192, 2254, 2324, 2386, 2450, 2510, 2579, 2642, 2716, 2778, 2842, 2908, 2979, 3042, 3095]}, {"subject_area"=>"/Medicine and health sciences", "average_usage"=>[303, 571, 709, 823, 937, 1038, 1133, 1216, 1298, 1370, 1447, 1518, 1588, 1656, 1725, 1790, 1856, 1926, 1992, 2054, 2118, 2182, 2242, 2301, 2363, 2425, 2484, 2544, 2602, 2662, 2716, 2776, 2841, 2901, 2960, 3016, 3071]}, {"subject_area"=>"/Medicine and health sciences/Anatomy and physiology", "average_usage"=>[296, 554, 686, 802, 910, 1014, 1104, 1195, 1277, 1349, 1419, 1483, 1551, 1620, 1690, 1757, 1820, 1888, 1957, 2017, 2081, 2140, 2202, 2259]}, {"subject_area"=>"/Medicine and health sciences/Hematology", "average_usage"=>[318, 581, 714, 833, 954, 1053, 1145, 1241, 1327, 1405, 1490, 1556, 1632, 1699, 1767, 1834, 1898, 1978, 2041, 2103, 2165, 2225, 2282, 2345, 2403, 2460, 2530, 2582, 2659, 2711, 2768, 2819, 2879, 2939, 2997, 3052, 3100]}]}
Loading … Spinner
There are currently no alerts