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Mendeley | Further Information

{"title"=>"What's so hot about recombination hotspots?", "type"=>"generic", "authors"=>[{"first_name"=>"Jody", "last_name"=>"Hey", "scopus_author_id"=>"7102045548"}], "year"=>2004, "source"=>"PLoS Biology", "identifiers"=>{"sgr"=>"19344365136", "pmid"=>"15208734", "pui"=>"39234432", "isbn"=>"1544-9173", "scopus"=>"2-s2.0-19344365136", "doi"=>"10.1371/journal.pbio.0020190", "issn"=>"15449173"}, "id"=>"0f965083-bfa9-3741-9063-85bbb1ea52ca", "abstract"=>"Recombination is a nearly ubituitous feature of genomes; where and when it occurs can provide insights about its evolution and can affect our ability to identify genes that cause disease", "link"=>"http://www.mendeley.com/research/whats-so-hot-about-recombination-hotspots-4", "reader_count"=>127, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>9, "Researcher"=>40, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>44, "Student > Postgraduate"=>3, "Student > Master"=>9, "Other"=>2, "Student > Bachelor"=>9, "Lecturer"=>3, "Lecturer > Senior Lecturer"=>2, "Professor"=>4}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>9, "Researcher"=>40, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>44, "Student > Postgraduate"=>3, "Student > Master"=>9, "Other"=>2, "Student > Bachelor"=>9, "Lecturer"=>3, "Lecturer > Senior Lecturer"=>2, "Professor"=>4}, "reader_count_by_subject_area"=>{"Engineering"=>1, "Environmental Science"=>2, "Biochemistry, Genetics and Molecular Biology"=>12, "Mathematics"=>6, "Medicine and Dentistry"=>3, "Agricultural and Biological Sciences"=>90, "Physics and Astronomy"=>4, "Psychology"=>1, "Computer Science"=>5, "Earth and Planetary Sciences"=>3}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Physics and Astronomy"=>{"Physics and Astronomy"=>4}, "Psychology"=>{"Psychology"=>1}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>90}, "Computer Science"=>{"Computer Science"=>5}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>12}, "Mathematics"=>{"Mathematics"=>6}, "Environmental Science"=>{"Environmental Science"=>2}}, "reader_count_by_country"=>{"Austria"=>1, "Sweden"=>1, "Sri Lanka"=>1, "United States"=>5, "Finland"=>1, "Brazil"=>1, "United Kingdom"=>6, "Mexico"=>1, "France"=>1, "Germany"=>1, "Spain"=>1}, "group_count"=>2}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/963837"], "description"=>"<p>Base positions that are not variable are not shown. Blocks of adjacent SNPs that revealed no evidence of historical recombination are flanked by vertical red bars. Two longer haplotype blocks are indicated in green. The presence of historical recombination was discerned by the four-gamete criterion. In brief, if the haplotypes for two SNPs, each with two bases (e.g., A/G at one SNP and C/T at the second), reveal all four possible combinations (i.e., A-C, A-T, GC, and G-T) then this is evidence that there has been a recombination event between these SNPs in the history of the sample of haplotypes (<a href=\"http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020190#pbio-0020190-Hudson1\" target=\"_blank\">Hudson and Kaplan 1985</a>). If haplotype blocks are long, then it is possible to represent much of the haplotype diversity using just a small sample of the SNPs found within that region.</p>", "links"=>[], "tags"=>["hypothetical", "aligned", "haplotypes", "snps"], "article_id"=>633784, "categories"=>["Ecology", "Genetics", "Infectious Diseases", "Evolutionary Biology"], "users"=>["Jody Hey"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020190.g001", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_Hypothetical_Example_of_Eight_Aligned_Haplotypes_for_All_the_SNPs_Found_in_a_Region_/633784", "title"=>"A Hypothetical Example of Eight Aligned Haplotypes for All the SNPs Found in a Region", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 09:14:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/963927"], "description"=>"<div><p>(A) Model of the SC. Lateral elements (light blue rods) of homologous chromosomes align and synapse together via a meshwork of transverse filaments (black lines) and longitudinal filaments (dark blue rods). The longitudinal filaments are collectively referred to as the “central element” of the SC. Ellipsoidal structures called recombination nodules (gray ellipsoid) are constructed on the central region of the SC. As their name implies, recombination nodules are believed to be involved in facilitating meiotic recombination (crossing over). The chromatin (red loops) of each homologue is attached to its corresponding lateral element. Because there are two “sister chromatids” in each homologue, two loops are shown extending laterally from each point along a lateral element.</p>\n <p>(B) Top: Set of tomato SCs. Chromatin “sheaths” are visible around each SC. Bottom: Two tomato SCs. The chromatin has been stripped from the SCs, allowing the details of the SC to be observed. Each SC has a kinetochore (“ball-like” structure) at its centromere. Recombination nodules, ellipsoidal structures found on the central regions of SCs, mark the sites of crossover events (see inset). Images and legend courtesy of Daniel G. Peterson, Mississippi Genome Exploration Laboratory, Mississippi State University, Mississippi State, Mississippi, United States (<a href=\"http://www.msstate.edu/research/mgel/index.htm)\" target=\"_blank\">http://www.msstate.edu/research/mgel/index.htm)</a>.</p></div>", "links"=>[], "tags"=>["synaptonemal"], "article_id"=>633878, "categories"=>["Ecology", "Genetics", "Infectious Diseases", "Evolutionary Biology"], "users"=>["Jody Hey"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0020190.g002", "stats"=>{"downloads"=>6, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_Synaptonemal_Complex_/633878", "title"=>"The Synaptonemal Complex", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 09:14:51"}

PMC Usage Stats | Further Information

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Relative Metric

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