A Map of Recent Positive Selection in the Human Genome
Publication Date
March 07, 2006
Journal
PLOS Biology
Authors
Benjamin F Voight, Sridhar Kudaravalli, Xiaoquan Wen & Jonathan K Pritchard
Volume
4
Issue
3
Pages
e72
DOI
https://dx.plos.org/10.1371/journal.pbio.0040072
Publisher URL
http://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.0040072
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/16494531
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382018
Europe PMC
http://europepmc.org/abstract/MED/16494531
Web of Science
000235991300016
Scopus
33646245175
Mendeley
http://www.mendeley.com/research/map-recent-positive-selection-human-genome-1
Events
Loading … Spinner

CiteULike | Further Information

Mendeley | Further Information

{"title"=>"A map of recent positive selection in the human genome", "type"=>"journal", "authors"=>[{"first_name"=>"Benjamin F.", "last_name"=>"Voight", "scopus_author_id"=>"10339684700"}, {"first_name"=>"Sridhar", "last_name"=>"Kudaravalli", "scopus_author_id"=>"12783153600"}, {"first_name"=>"Xiaoquan", "last_name"=>"Wen", "scopus_author_id"=>"8846776400"}, {"first_name"=>"Jonathan K.", "last_name"=>"Pritchard", "scopus_author_id"=>"57200979225"}], "year"=>2006, "source"=>"PLoS Biology", "identifiers"=>{"issn"=>"15457885", "scopus"=>"2-s2.0-33644981509", "pui"=>"43396255", "doi"=>"10.1371/journal.pbio.0040072", "isbn"=>"1545-7885 (Electronic) 1544-9173 (Linking)", "sgr"=>"33644981509", "pmid"=>"16494531"}, "id"=>"5f572908-a6c9-3e52-b022-9eb68358d777", "abstract"=>"The identification of signals of very recent positive selection provides information about the adaptation of modern humans to local conditions. We report here on a genome-wide scan for signals of very recent positive selection in favor of variants that have not yet reached fixation. We describe a new analytical method for scanning single nucleotide polymorphism (SNP) data for signals of recent selection, and apply this to data from the International HapMap Project. In all three continental groups we find widespread signals of recent positive selection. Most signals are region-specific, though a significant excess are shared across groups. Contrary to some earlier low resolution studies that suggested a paucity of recent selection in sub-Saharan Africans, we find that by some measures our strongest signals of selection are from the Yoruba population. Finally, since these signals indicate the existence of genetic variants that have substantially different fitnesses, they must indicate loci that are the source of significant phenotypic variation. Though the relevant phenotypes are generally not known, such loci should be of particular interest in mapping studies of complex traits. For this purpose we have developed a set of SNPs that can be used to tag the strongest approximately 250 signals of recent selection in each population.", "link"=>"http://www.mendeley.com/research/map-recent-positive-selection-human-genome-1", "reader_count"=>1109, "reader_count_by_academic_status"=>{"Unspecified"=>13, "Professor > Associate Professor"=>90, "Librarian"=>1, "Researcher"=>270, "Student > Doctoral Student"=>42, "Student > Ph. D. Student"=>341, "Student > Postgraduate"=>41, "Student > Master"=>120, "Other"=>22, "Student > Bachelor"=>102, "Lecturer"=>11, "Lecturer > Senior Lecturer"=>9, "Professor"=>46}, "reader_count_by_user_role"=>{"Unspecified"=>13, "Professor > Associate Professor"=>90, "Librarian"=>1, "Researcher"=>270, "Student > Doctoral Student"=>42, "Student > Ph. D. Student"=>341, "Student > Postgraduate"=>41, "Student > Master"=>120, "Other"=>22, "Student > Bachelor"=>102, "Lecturer"=>11, "Lecturer > Senior Lecturer"=>9, "Professor"=>46}, "reader_count_by_subject_area"=>{"Unspecified"=>35, "Agricultural and Biological Sciences"=>800, "Arts and Humanities"=>7, "Philosophy"=>3, "Veterinary Science and Veterinary Medicine"=>2, "Chemistry"=>1, "Computer Science"=>23, "Earth and Planetary Sciences"=>2, "Economics, Econometrics and Finance"=>2, "Engineering"=>5, "Environmental Science"=>12, "Biochemistry, Genetics and Molecular Biology"=>106, "Materials Science"=>1, "Mathematics"=>11, "Medicine and Dentistry"=>33, "Sports and Recreations"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>2, "Physics and Astronomy"=>1, "Psychology"=>27, "Social Sciences"=>29, "Immunology and Microbiology"=>2, "Linguistics"=>2}, "reader_count_by_subdiscipline"=>{"Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>33}, "Social Sciences"=>{"Social Sciences"=>29}, "Sports and Recreations"=>{"Sports and Recreations"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>27}, "Mathematics"=>{"Mathematics"=>11}, "Unspecified"=>{"Unspecified"=>35}, "Environmental Science"=>{"Environmental Science"=>12}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>2}, "Arts and Humanities"=>{"Arts and Humanities"=>7}, "Engineering"=>{"Engineering"=>5}, "Chemistry"=>{"Chemistry"=>1}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>2}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>2}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>2}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>800}, "Computer Science"=>{"Computer Science"=>23}, "Linguistics"=>{"Linguistics"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>106}, "Philosophy"=>{"Philosophy"=>3}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>2}}, "reader_count_by_country"=>{"Hong Kong"=>1, "United States"=>59, "Portugal"=>2, "Iceland"=>1, "Austria"=>3, "Sweden"=>2, "Netherlands"=>1, "Korea (South)"=>1, "Ireland"=>1, "China"=>2, "Brazil"=>7, "France"=>8, "Chile"=>2, "Colombia"=>2, "Argentina"=>3, "Romania"=>1, "Uruguay"=>1, "United Kingdom"=>18, "Switzerland"=>5, "Spain"=>9, "New Zealand"=>3, "Canada"=>4, "Turkey"=>1, "Belgium"=>1, "Norway"=>2, "Finland"=>2, "Denmark"=>3, "Italy"=>6, "South Africa"=>2, "Mexico"=>2, "Israel"=>1, "Australia"=>3, "Germany"=>5}, "group_count"=>42}

CrossRef

PubMed Central | Further Information

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/33646245175"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/33646245175?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33646245175&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=33646245175&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/33646245175", "dc:identifier"=>"SCOPUS_ID:33646245175", "eid"=>"2-s2.0-33646245175", "dc:title"=>"Erratum: A map of recent positive selection in the human genome (Plos Biology 4,3 DOI:10.1371/journal.pbio.0040072)", "dc:creator"=>"Voight B.", "prism:publicationName"=>"PLoS Biology", "prism:issn"=>"15457885", "prism:eIssn"=>"15457885", "prism:volume"=>"4", "prism:issueIdentifier"=>"4", "prism:pageRange"=>"659", "prism:coverDate"=>"2006-01-01", "prism:coverDisplayDate"=>"April 2006", "prism:doi"=>"10.1371/journal.pbio.0040072", "citedby-count"=>"85", "prism:aggregationType"=>"Journal", "subtype"=>"er", "subtypeDescription"=>"Erratum", "source-id"=>"12977", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosbiology%2Farticle%3Fid%3D10.1371%252Fjournal.pbio.0040072", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments | Further Information

Twitter

Counter

  • {"month"=>"2", "year"=>"2006", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"1"}
  • {"month"=>"3", "year"=>"2006", "pdf_views"=>"4522", "xml_views"=>"37", "html_views"=>"11808"}
  • {"month"=>"4", "year"=>"2006", "pdf_views"=>"1025", "xml_views"=>"9", "html_views"=>"4091"}
  • {"month"=>"5", "year"=>"2006", "pdf_views"=>"544", "xml_views"=>"4", "html_views"=>"2330"}
  • {"month"=>"6", "year"=>"2006", "pdf_views"=>"311", "xml_views"=>"2", "html_views"=>"1084"}
  • {"month"=>"7", "year"=>"2006", "pdf_views"=>"460", "xml_views"=>"9", "html_views"=>"1673"}
  • {"month"=>"8", "year"=>"2006", "pdf_views"=>"239", "xml_views"=>"5", "html_views"=>"1242"}
  • {"month"=>"9", "year"=>"2006", "pdf_views"=>"268", "xml_views"=>"2", "html_views"=>"1426"}
  • {"month"=>"10", "year"=>"2006", "pdf_views"=>"289", "xml_views"=>"6", "html_views"=>"1466"}
  • {"month"=>"11", "year"=>"2006", "pdf_views"=>"192", "xml_views"=>"6", "html_views"=>"2332"}
  • {"month"=>"12", "year"=>"2006", "pdf_views"=>"123", "xml_views"=>"6", "html_views"=>"1561"}
  • {"month"=>"1", "year"=>"2007", "pdf_views"=>"164", "xml_views"=>"7", "html_views"=>"727"}
  • {"month"=>"2", "year"=>"2007", "pdf_views"=>"122", "xml_views"=>"6", "html_views"=>"598"}
  • {"month"=>"3", "year"=>"2007", "pdf_views"=>"184", "xml_views"=>"7", "html_views"=>"1251"}
  • {"month"=>"4", "year"=>"2007", "pdf_views"=>"168", "xml_views"=>"8", "html_views"=>"1062"}
  • {"month"=>"5", "year"=>"2007", "pdf_views"=>"138", "xml_views"=>"4", "html_views"=>"718"}
  • {"month"=>"6", "year"=>"2007", "pdf_views"=>"165", "xml_views"=>"6", "html_views"=>"547"}
  • {"month"=>"7", "year"=>"2007", "pdf_views"=>"136", "xml_views"=>"4", "html_views"=>"553"}
  • {"month"=>"8", "year"=>"2007", "pdf_views"=>"96", "xml_views"=>"7", "html_views"=>"399"}
  • {"month"=>"9", "year"=>"2007", "pdf_views"=>"129", "xml_views"=>"3", "html_views"=>"702"}
  • {"month"=>"10", "year"=>"2007", "pdf_views"=>"175", "xml_views"=>"5", "html_views"=>"715"}
  • {"month"=>"11", "year"=>"2007", "pdf_views"=>"189", "xml_views"=>"16", "html_views"=>"682"}
  • {"month"=>"12", "year"=>"2007", "pdf_views"=>"146", "xml_views"=>"4", "html_views"=>"593"}
  • {"month"=>"1", "year"=>"2008", "pdf_views"=>"148", "xml_views"=>"7", "html_views"=>"566"}
  • {"month"=>"2", "year"=>"2008", "pdf_views"=>"142", "xml_views"=>"4", "html_views"=>"643"}
  • {"month"=>"3", "year"=>"2008", "pdf_views"=>"166", "xml_views"=>"7", "html_views"=>"647"}
  • {"month"=>"4", "year"=>"2008", "pdf_views"=>"137", "xml_views"=>"6", "html_views"=>"724"}
  • {"month"=>"5", "year"=>"2008", "pdf_views"=>"134", "xml_views"=>"7", "html_views"=>"531"}
  • {"month"=>"6", "year"=>"2008", "pdf_views"=>"90", "xml_views"=>"6", "html_views"=>"521"}
  • {"month"=>"7", "year"=>"2008", "pdf_views"=>"110", "xml_views"=>"5", "html_views"=>"456"}
  • {"month"=>"8", "year"=>"2008", "pdf_views"=>"91", "xml_views"=>"7", "html_views"=>"440"}
  • {"month"=>"9", "year"=>"2008", "pdf_views"=>"98", "xml_views"=>"7", "html_views"=>"620"}
  • {"month"=>"10", "year"=>"2008", "pdf_views"=>"125", "xml_views"=>"10", "html_views"=>"470"}
  • {"month"=>"11", "year"=>"2008", "pdf_views"=>"138", "xml_views"=>"11", "html_views"=>"607"}
  • {"month"=>"12", "year"=>"2008", "pdf_views"=>"92", "xml_views"=>"5", "html_views"=>"384"}
  • {"month"=>"1", "year"=>"2009", "pdf_views"=>"138", "xml_views"=>"9", "html_views"=>"448"}
  • {"month"=>"2", "year"=>"2009", "pdf_views"=>"152", "xml_views"=>"3", "html_views"=>"498"}
  • {"month"=>"3", "year"=>"2009", "pdf_views"=>"154", "xml_views"=>"6", "html_views"=>"610"}
  • {"month"=>"4", "year"=>"2009", "pdf_views"=>"127", "xml_views"=>"1", "html_views"=>"497"}
  • {"month"=>"5", "year"=>"2009", "pdf_views"=>"74", "xml_views"=>"3", "html_views"=>"264"}
  • {"month"=>"6", "year"=>"2009", "pdf_views"=>"91", "xml_views"=>"0", "html_views"=>"444"}
  • {"month"=>"7", "year"=>"2009", "pdf_views"=>"74", "xml_views"=>"3", "html_views"=>"287"}
  • {"month"=>"8", "year"=>"2009", "pdf_views"=>"82", "xml_views"=>"0", "html_views"=>"373"}
  • {"month"=>"9", "year"=>"2009", "pdf_views"=>"103", "xml_views"=>"1", "html_views"=>"382"}
  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"71", "xml_views"=>"0", "html_views"=>"397"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"80", "xml_views"=>"1", "html_views"=>"343"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"82", "xml_views"=>"2", "html_views"=>"343"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"90", "xml_views"=>"3", "html_views"=>"355"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"73", "xml_views"=>"1", "html_views"=>"371"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"108", "xml_views"=>"0", "html_views"=>"412"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"87", "xml_views"=>"4", "html_views"=>"372"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"94", "xml_views"=>"1", "html_views"=>"394"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"85", "xml_views"=>"2", "html_views"=>"281"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"78", "xml_views"=>"1", "html_views"=>"256"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"74", "xml_views"=>"0", "html_views"=>"301"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"103", "xml_views"=>"2", "html_views"=>"360"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"134", "xml_views"=>"4", "html_views"=>"468"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"148", "xml_views"=>"3", "html_views"=>"619"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"77", "xml_views"=>"0", "html_views"=>"360"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"105", "xml_views"=>"4", "html_views"=>"360"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"123", "xml_views"=>"1", "html_views"=>"377"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"119", "xml_views"=>"2", "html_views"=>"476"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"113", "xml_views"=>"0", "html_views"=>"412"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"80", "xml_views"=>"1", "html_views"=>"300"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"74", "xml_views"=>"0", "html_views"=>"255"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"57", "xml_views"=>"0", "html_views"=>"247"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"64", "xml_views"=>"2", "html_views"=>"301"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"91", "xml_views"=>"0", "html_views"=>"421"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"116", "xml_views"=>"2", "html_views"=>"583"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"130", "xml_views"=>"0", "html_views"=>"629"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"80", "xml_views"=>"2", "html_views"=>"428"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"89", "xml_views"=>"1", "html_views"=>"358"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"174", "xml_views"=>"3", "html_views"=>"567"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"129", "xml_views"=>"1", "html_views"=>"471"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"125", "xml_views"=>"2", "html_views"=>"505"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"136", "xml_views"=>"2", "html_views"=>"632"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"98", "xml_views"=>"1", "html_views"=>"371"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"82", "xml_views"=>"0", "html_views"=>"344"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"79", "xml_views"=>"5", "html_views"=>"343"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"105", "xml_views"=>"4", "html_views"=>"573"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"112", "xml_views"=>"1", "html_views"=>"734"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"102", "xml_views"=>"0", "html_views"=>"554"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"110", "xml_views"=>"1", "html_views"=>"524"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"103", "xml_views"=>"3", "html_views"=>"648"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"108", "xml_views"=>"7", "html_views"=>"885"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"111", "xml_views"=>"1", "html_views"=>"784"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"108", "xml_views"=>"2", "html_views"=>"874"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"126", "xml_views"=>"0", "html_views"=>"830"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"118", "xml_views"=>"1", "html_views"=>"562"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"90", "xml_views"=>"1", "html_views"=>"593"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"80", "xml_views"=>"1", "html_views"=>"566"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"79", "xml_views"=>"1", "html_views"=>"621"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"130", "xml_views"=>"3", "html_views"=>"957"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"109", "xml_views"=>"3", "html_views"=>"925"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"92", "xml_views"=>"2", "html_views"=>"806"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"99", "xml_views"=>"1", "html_views"=>"715"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"91", "xml_views"=>"1", "html_views"=>"802"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"103", "xml_views"=>"3", "html_views"=>"584"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"138", "xml_views"=>"5", "html_views"=>"880"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"131", "xml_views"=>"0", "html_views"=>"986"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"89", "xml_views"=>"5", "html_views"=>"838"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"78", "xml_views"=>"3", "html_views"=>"743"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"62", "xml_views"=>"5", "html_views"=>"678"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"90", "xml_views"=>"3", "html_views"=>"991"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"113", "xml_views"=>"0", "html_views"=>"1150"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"113", "xml_views"=>"3", "html_views"=>"1012"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"73", "xml_views"=>"3", "html_views"=>"640"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"119", "xml_views"=>"1", "html_views"=>"745"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"73", "xml_views"=>"0", "html_views"=>"556"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"102", "xml_views"=>"0", "html_views"=>"672"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"70", "xml_views"=>"1", "html_views"=>"621"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"78", "xml_views"=>"1", "html_views"=>"476"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"67", "xml_views"=>"0", "html_views"=>"541"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"71", "xml_views"=>"0", "html_views"=>"457"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"64", "xml_views"=>"0", "html_views"=>"377"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"75", "xml_views"=>"0", "html_views"=>"502"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"90", "xml_views"=>"0", "html_views"=>"571"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"92", "xml_views"=>"0", "html_views"=>"528"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"51", "xml_views"=>"0", "html_views"=>"416"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"68", "xml_views"=>"0", "html_views"=>"377"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"109", "xml_views"=>"0", "html_views"=>"472"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"81", "xml_views"=>"0", "html_views"=>"487"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"104", "xml_views"=>"0", "html_views"=>"511"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"101", "xml_views"=>"0", "html_views"=>"476"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"98", "xml_views"=>"0", "html_views"=>"385"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"70", "xml_views"=>"0", "html_views"=>"303"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"82", "xml_views"=>"0", "html_views"=>"364"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"83", "xml_views"=>"0", "html_views"=>"535"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"110", "xml_views"=>"0", "html_views"=>"552"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"55", "xml_views"=>"0", "html_views"=>"638"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"116", "xml_views"=>"2", "html_views"=>"404"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"123", "xml_views"=>"1", "html_views"=>"477"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"115", "xml_views"=>"3", "html_views"=>"560"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"115", "xml_views"=>"1", "html_views"=>"597"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"112", "xml_views"=>"6", "html_views"=>"584"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"89", "xml_views"=>"3", "html_views"=>"656"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"80", "xml_views"=>"2", "html_views"=>"451"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"75", "xml_views"=>"3", "html_views"=>"422"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"64", "xml_views"=>"5", "html_views"=>"349"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"64", "xml_views"=>"5", "html_views"=>"423"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"104", "xml_views"=>"3", "html_views"=>"565"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"100", "xml_views"=>"0", "html_views"=>"515"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"87", "xml_views"=>"1", "html_views"=>"480"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"97", "xml_views"=>"2", "html_views"=>"356"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"85", "xml_views"=>"1", "html_views"=>"215"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"103", "xml_views"=>"1", "html_views"=>"329"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"120", "xml_views"=>"0", "html_views"=>"370"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"109", "xml_views"=>"5", "html_views"=>"291"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"115", "xml_views"=>"11", "html_views"=>"220"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"91", "xml_views"=>"10", "html_views"=>"187"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"83", "xml_views"=>"2", "html_views"=>"209"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"94", "xml_views"=>"2", "html_views"=>"226"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"130", "xml_views"=>"3", "html_views"=>"319"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"96", "xml_views"=>"1", "html_views"=>"295"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"102", "xml_views"=>"1", "html_views"=>"273"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"114", "xml_views"=>"0", "html_views"=>"333"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"68", "xml_views"=>"1", "html_views"=>"220"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"119", "xml_views"=>"2", "html_views"=>"264"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"123", "xml_views"=>"1", "html_views"=>"302"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"94", "xml_views"=>"0", "html_views"=>"244"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"91", "xml_views"=>"1", "html_views"=>"195"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"118", "xml_views"=>"1", "html_views"=>"196"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"108", "xml_views"=>"0", "html_views"=>"170"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"78", "xml_views"=>"0", "html_views"=>"213"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"61", "xml_views"=>"0", "html_views"=>"153"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/474644", "https://ndownloader.figshare.com/files/474699", "https://ndownloader.figshare.com/files/474742", "https://ndownloader.figshare.com/files/474783", "https://ndownloader.figshare.com/files/474827", "https://ndownloader.figshare.com/files/474863", "https://ndownloader.figshare.com/files/474894", "https://ndownloader.figshare.com/files/474920", "https://ndownloader.figshare.com/files/474949", "https://ndownloader.figshare.com/files/474971", "https://ndownloader.figshare.com/files/474990", "https://ndownloader.figshare.com/files/475009", "https://ndownloader.figshare.com/files/475026", "https://ndownloader.figshare.com/files/475042", "https://ndownloader.figshare.com/files/475056", "https://ndownloader.figshare.com/files/475069", "https://ndownloader.figshare.com/files/475083", "https://ndownloader.figshare.com/files/475095", "https://ndownloader.figshare.com/files/475112", "https://ndownloader.figshare.com/files/475124", "https://ndownloader.figshare.com/files/475137", "https://ndownloader.figshare.com/files/475146", "https://ndownloader.figshare.com/files/475157", "https://ndownloader.figshare.com/files/475164", "https://ndownloader.figshare.com/files/475173", "https://ndownloader.figshare.com/files/475181", "https://ndownloader.figshare.com/files/475188", "https://ndownloader.figshare.com/files/475195", "https://ndownloader.figshare.com/files/475199", "https://ndownloader.figshare.com/files/475200", "https://ndownloader.figshare.com/files/475202", "https://ndownloader.figshare.com/files/475204", "https://ndownloader.figshare.com/files/475205", "https://ndownloader.figshare.com/files/475206", "https://ndownloader.figshare.com/files/475208", "https://ndownloader.figshare.com/files/475210", "https://ndownloader.figshare.com/files/475211", "https://ndownloader.figshare.com/files/475213"], "description"=>"<div><p>The identification of signals of very recent positive selection provides information about the adaptation of modern humans to local conditions. We report here on a genome-wide scan for signals of very recent positive selection in favor of variants that have not yet reached fixation. We describe a new analytical method for scanning single nucleotide polymorphism (SNP) data for signals of recent selection, and apply this to data from the International HapMap Project. In all three continental groups we find widespread signals of recent positive selection. Most signals are region-specific, though a significant excess are shared across groups. Contrary to some earlier low resolution studies that suggested a paucity of recent selection in sub-Saharan Africans, we find that by some measures our strongest signals of selection are from the Yoruba population. Finally, since these signals indicate the existence of genetic variants that have substantially different fitnesses, they must indicate loci that are the source of significant phenotypic variation. Though the relevant phenotypes are generally not known, such loci should be of particular interest in mapping studies of complex traits. For this purpose we have developed a set of SNPs that can be used to tag the strongest ∼250 signals of recent selection in each population.</p> </div>", "links"=>[], "tags"=>["genome"], "article_id"=>153568, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>["https://dx.doi.org/10.1371/journal.pbio.0040072.sg001", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg002", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg003", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg004", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg005", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg006", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg007", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg008", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg009", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg010", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg011", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg012", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg013", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg014", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg015", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg016", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg017", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg018", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg019", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg020", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg021", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg022", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg023", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg024", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg025", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg026", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg027", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg028", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg029", "https://dx.doi.org/10.1371/journal.pbio.0040072.sg030", "https://dx.doi.org/10.1371/journal.pbio.0040072.sd001", "https://dx.doi.org/10.1371/journal.pbio.0040072.sd002", "https://dx.doi.org/10.1371/journal.pbio.0040072.sd003", "https://dx.doi.org/10.1371/journal.pbio.0040072.sd004", "https://dx.doi.org/10.1371/journal.pbio.0040072.st001", "https://dx.doi.org/10.1371/journal.pbio.0040072.st002", "https://dx.doi.org/10.1371/journal.pbio.0040072.st003", "https://dx.doi.org/10.1371/journal.pbio.0040072.st004"], "stats"=>{"downloads"=>35, "page_views"=>21, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/A_Map_of_Recent_Positive_Selection_in_the_Human_Genome/153568", "title"=>"A Map of Recent Positive Selection in the Human Genome", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2006-03-07 00:59:28"}
  • {"files"=>["https://ndownloader.figshare.com/files/959723"], "description"=>"<p>SNPs with |iHS| >2.5 (top 1%) are plotted. The bottom plot combines signals for all three populations, plotting only SNPs with derived frequency >0.5 and iHS <−2.5. Such SNPs correspond to high-frequency-derived SNPs in the range for which our test is most powerful. The short vertical bars below each plot indicate 100-kb windows whose signals are in the top 1% of windows genome-wide.</p>", "links"=>[], "tags"=>["chromosome", "snps", "ihs", "discrete", "clusters"], "article_id"=>629741, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g003", "stats"=>{"downloads"=>2, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Plots_of_Chromosome_2_SNPs_with_Extreme_iHS_Values_Indicate_Discrete_Clusters_of_Signals_/629741", "title"=>"Plots of Chromosome 2 SNPs with Extreme iHS Values Indicate Discrete Clusters of Signals", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:44:55"}
  • {"files"=>["https://ndownloader.figshare.com/files/959616"], "description"=>"<p>Simulation parameters are matched to the Yoruba data, with <i>σ</i> = 150. Tests are abased on 51-SNP windows centered on a selected site. The upper curves (iHS) are based on counting the number of SNPs in the window for which |iHS| >2. The green line indicates power when the actual SNP under selection is excluded from the analysis. The lower lines plot power using Fay and Wu's <i>H</i>, and Tajima's <i>D</i>, both calculated using the ascertained genotype data. The line marked <i>t</i> = +200 indicates the power 200 generations after fixation (<i>N<sub>e</sub></i> = 10<sup>4</sup>). Critical values for each statistic at <i>p</i> = 0.01 were obtained using identical simulations with <i>σ</i> = 0.</p>", "links"=>[], "tags"=>["sweeps-in-progress"], "article_id"=>629640, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g002", "stats"=>{"downloads"=>2, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Power_to_Detect_Sweeps_in_Progress_at_a_p_Value_of_0_01_Using_Various_Statistics_/629640", "title"=>"Power to Detect Sweeps-in-Progress at a <i>p</i>-Value of 0.01, Using Various Statistics", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:44:11"}
  • {"files"=>["https://ndownloader.figshare.com/files/959531"], "description"=>"<div><p>(A) Decay of haplotypes in a single region in which a new selected allele (red, center column) is sweeping to fixation, replacing the ancestral allele (blue). Horizontal lines are haplotypes; SNP positions are marked below the haplotype plot using blue for SNPs with intermediate allele frequencies (minor allele >0.2), and red otherwise. For a given SNP, adjacent haplotypes with the same color carry identical genotypes everywhere between that SNP and the central (selected) site. The left- and right-hand sides are sorted separately. Haplotypes are no longer plotted beyond the points at which they become unique.</p>\n <p>(B) Decay of haplotype homozygosity for ten replicate simulations. When the core SNP is neutral (<i>σ</i> = 0; left side) the haplotype homozygosity decays at similar rates for both ancestral and derived alleles. When the derived alleles are favored (<i>σ</i> = 2<i>Ns</i> = 250; right side), the haplotype homozygosity decays much slower for the derived alleles than for the ancestral alleles. The discrepancy in the overall areas spanned by these two curves forms the basis of our text for selection (iHS).</p></div>", "links"=>[], "tags"=>["ehh", "simulated", "allele"], "article_id"=>629556, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g001", "stats"=>{"downloads"=>2, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Decay_of_EHH_in_Simulated_Data_for_an_Allele_at_Frequency_0_5_/629556", "title"=>"Decay of EHH in Simulated Data for an Allele at Frequency 0.5", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:43:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/959845"], "description"=>"<p>The left-hand plot shows the probability that a 51-SNP window centered on a given SNP is in the lowest 1% of the empirical distribution for Fay and Wu's <i>H</i> in neutral simulated data, and in the Yoruba data overall. Notice that in neutral simulations, there is essentially no correlation between iHS and <i>H</i>. Right-hand plot: In contrast, in simulations with selection (cyan line, <i>σ</i> = 100) there is a big increase in the rate of significant <i>H</i> values for high-frequency selected alleles with strongly negative iHS (<−2.5). The same pattern is seen for the real data (red line). In the real data, sites with strongly positive iHS (>2.5) show an increase in the rate of positive <i>H</i> scores at low derived allele frequencies (magenta line). The latter probably reflects instances of an ancestral allele hitchhiking to high frequency with a selected sweep.</p>", "links"=>[], "tags"=>["ihs", "yoruba"], "article_id"=>629866, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g005", "stats"=>{"downloads"=>2, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Strong_Correlation_between_iHS_and_H_asc_for_the_Yoruba_Data_/629866", "title"=>"Strong Correlation between iHS and H<sub>asc</sub> for the Yoruba Data", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:45:57"}
  • {"files"=>["https://ndownloader.figshare.com/files/959958"], "description"=>"<p>The columns show (left) scatter plots of negative iHS scores, (center) haplotype plots, and (right) decay of haplotype homozygosity. In each case the core SNP for the center and right-hand plots was chosen as a SNP with high negative iHS score (starred in the scatter plots); the allele marked in red is derived. For each signal, values are listed for the derived allele frequency (<i>p<sub>d</sub></i>) and the local deCode recombination rate estimate.</p>", "links"=>[], "tags"=>["regions", "discussed"], "article_id"=>629975, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g006", "stats"=>{"downloads"=>3, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Signals_of_Selection_for_Three_Candidate_Selection_Regions_Discussed_in_the_Text_/629975", "title"=>"Signals of Selection for Three Candidate Selection Regions Discussed in the Text", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:46:45"}
  • {"files"=>["https://ndownloader.figshare.com/files/960088"], "description"=>"<p>The numbers listed inside circles represent the numbers of 100-kb windows that are in the top 1% of the empirical distributions in at least one population. The numbers in the intersection regions are in the top 1% for one population, and the top 5% for one or both of the other populations. The counts that would be expected if signals were independent across populations are shown in parentheses. The number of windows not in any circle is reported in the upper-left corner.</p>", "links"=>[], "tags"=>["ihs", "signals"], "article_id"=>630098, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g007", "stats"=>{"downloads"=>9, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sharing_of_iHS_Signals_between_Populations_/630098", "title"=>"Sharing of iHS Signals between Populations", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:47:39"}
  • {"files"=>["https://ndownloader.figshare.com/files/959804"], "description"=>"<p>The upper and lower lines mark the boundaries of the central 99% distribution of the unstandardized iHS ratio, as a function of derived allele frequency. The gray lines plot results for a range of plausible demographic models. The fatter tails in the real data are consistent with the action of selection.</p>", "links"=>[], "tags"=>["unstandardized", "ihs", "snps", "yoruba", "matched"], "article_id"=>629823, "categories"=>["Biological Sciences", "Mathematics", "Genetics", "Evolutionary Biology"], "users"=>["Benjamin F Voight", "Sridhar Kudaravalli", "Xiaoquan Wen", "Jonathan K Pritchard"], "doi"=>"https://dx.doi.org/10.1371/journal.pbio.0040072.g004", "stats"=>{"downloads"=>6, "page_views"=>16, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Central_99_Range_of_Unstandardized_iHS_for_SNPs_in_the_Yoruba_Data_and_for_SNPs_in_Matched_Neutral_Simulations_/629823", "title"=>"Central 99% Range of Unstandardized iHS for SNPs in the Yoruba Data and for SNPs in Matched Neutral Simulations", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:45:33"}

PMC Usage Stats | Further Information

  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"47", "unique-ip"=>"33", "pdf"=>"22", "year"=>"2010", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"20"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"31", "year"=>"2010", "pdf"=>"13", "unique-ip"=>"24", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"9"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"26", "unique-ip"=>"25", "pdf"=>"15", "year"=>"2010", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"49", "year"=>"2010", "pdf"=>"27", "unique-ip"=>"40", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"30"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"47", "unique-ip"=>"43", "pdf"=>"31", "year"=>"2010", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"9"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"28", "year"=>"2010", "pdf"=>"22", "unique-ip"=>"27", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"8", "abstract"=>"0", "full-text"=>"20", "unique-ip"=>"23", "pdf"=>"16", "year"=>"2010", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"25", "year"=>"2010", "pdf"=>"13", "unique-ip"=>"24", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"19"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"35", "unique-ip"=>"34", "pdf"=>"18", "year"=>"2010", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"33", "year"=>"2010", "pdf"=>"17", "unique-ip"=>"36", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"29", "unique-ip"=>"31", "pdf"=>"17", "year"=>"2010", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"44", "year"=>"2010", "pdf"=>"35", "unique-ip"=>"40", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"21", "unique-ip"=>"30", "pdf"=>"21", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"32", "year"=>"2011", "pdf"=>"24", "unique-ip"=>"36", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"27"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"39", "unique-ip"=>"39", "pdf"=>"22", "year"=>"2011", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"46", "year"=>"2011", "pdf"=>"30", "unique-ip"=>"41", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"44", "unique-ip"=>"46", "pdf"=>"33", "year"=>"2011", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"6"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"34", "year"=>"2011", "pdf"=>"34", "unique-ip"=>"36", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"13"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"47", "unique-ip"=>"30", "pdf"=>"15", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"33"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"44", "year"=>"2011", "pdf"=>"16", "unique-ip"=>"36", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"18"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"27", "unique-ip"=>"20", "pdf"=>"14", "year"=>"2011", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"28", "year"=>"2011", "pdf"=>"14", "unique-ip"=>"33", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"34", "unique-ip"=>"35", "pdf"=>"20", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"16"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"30", "year"=>"2011", "pdf"=>"15", "unique-ip"=>"26", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"15"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"45", "unique-ip"=>"36", "pdf"=>"27", "year"=>"2012", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"36", "year"=>"2012", "pdf"=>"28", "unique-ip"=>"42", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"2", "abstract"=>"0", "full-text"=>"48", "unique-ip"=>"42", "pdf"=>"31", "year"=>"2012", "figure"=>"18", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"6", "abstract"=>"4", "full-text"=>"33", "year"=>"2012", "pdf"=>"13", "unique-ip"=>"33", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"10"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"31", "unique-ip"=>"35", "pdf"=>"22", "year"=>"2012", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"3", "scanned-page-browse"=>"352", "cited-by"=>"2", "abstract"=>"14", "full-text"=>"39", "year"=>"2006", "pdf"=>"344", "unique-ip"=>"108", "figure"=>"1299", "scanned-summary"=>"442", "supp-data"=>"399"}
  • {"scanned-page-browse"=>"87", "month"=>"4", "cited-by"=>"1", "abstract"=>"16", "full-text"=>"22", "unique-ip"=>"120", "pdf"=>"80", "year"=>"2006", "figure"=>"486", "scanned-summary"=>"161", "supp-data"=>"121"}
  • {"month"=>"5", "scanned-page-browse"=>"60", "cited-by"=>"0", "abstract"=>"12", "full-text"=>"26", "year"=>"2006", "pdf"=>"118", "unique-ip"=>"94", "figure"=>"463", "scanned-summary"=>"153", "supp-data"=>"107"}
  • {"scanned-page-browse"=>"45", "month"=>"6", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"12", "unique-ip"=>"0", "pdf"=>"69", "year"=>"2006", "figure"=>"216", "scanned-summary"=>"90", "supp-data"=>"63"}
  • {"month"=>"7", "scanned-page-browse"=>"42", "cited-by"=>"1", "abstract"=>"2", "full-text"=>"9", "year"=>"2006", "pdf"=>"5", "unique-ip"=>"7", "figure"=>"148", "scanned-summary"=>"83", "supp-data"=>"65"}
  • {"scanned-page-browse"=>"54", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"0", "pdf"=>"22", "year"=>"2006", "figure"=>"140", "scanned-summary"=>"58", "supp-data"=>"48"}
  • {"month"=>"9", "scanned-page-browse"=>"26", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2006", "pdf"=>"8", "unique-ip"=>"3", "figure"=>"81", "scanned-summary"=>"40", "supp-data"=>"42"}
  • {"scanned-page-browse"=>"39", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"7", "unique-ip"=>"19", "pdf"=>"38", "year"=>"2006", "figure"=>"150", "scanned-summary"=>"46", "supp-data"=>"51"}
  • {"month"=>"11", "scanned-page-browse"=>"69", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"7", "year"=>"2006", "pdf"=>"219", "unique-ip"=>"6", "figure"=>"381", "scanned-summary"=>"78", "supp-data"=>"77"}
  • {"scanned-page-browse"=>"31", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"0", "unique-ip"=>"8", "pdf"=>"29", "year"=>"2006", "figure"=>"115", "scanned-summary"=>"46", "supp-data"=>"46"}
  • {"month"=>"1", "scanned-page-browse"=>"41", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2007", "pdf"=>"28", "unique-ip"=>"5", "figure"=>"116", "scanned-summary"=>"40", "supp-data"=>"42"}
  • {"scanned-page-browse"=>"35", "month"=>"2", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"3", "unique-ip"=>"3", "pdf"=>"28", "year"=>"2007", "figure"=>"119", "scanned-summary"=>"49", "supp-data"=>"53"}
  • {"month"=>"3", "scanned-page-browse"=>"41", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2007", "pdf"=>"7", "unique-ip"=>"3", "figure"=>"107", "scanned-summary"=>"52", "supp-data"=>"57"}
  • {"scanned-page-browse"=>"28", "month"=>"4", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"1", "unique-ip"=>"3", "pdf"=>"21", "year"=>"2007", "figure"=>"93", "scanned-summary"=>"39", "supp-data"=>"56"}
  • {"month"=>"5", "scanned-page-browse"=>"36", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"4", "year"=>"2007", "pdf"=>"39", "unique-ip"=>"12", "figure"=>"155", "scanned-summary"=>"63", "supp-data"=>"62"}
  • {"scanned-page-browse"=>"33", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"5", "pdf"=>"12", "year"=>"2007", "figure"=>"97", "scanned-summary"=>"46", "supp-data"=>"45"}
  • {"month"=>"7", "scanned-page-browse"=>"29", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "year"=>"2007", "pdf"=>"20", "unique-ip"=>"1", "figure"=>"100", "scanned-summary"=>"47", "supp-data"=>"48"}
  • {"scanned-page-browse"=>"16", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"0", "pdf"=>"12", "year"=>"2007", "figure"=>"60", "scanned-summary"=>"31", "supp-data"=>"28"}
  • {"month"=>"9", "scanned-page-browse"=>"35", "cited-by"=>"2", "abstract"=>"0", "full-text"=>"0", "year"=>"2007", "pdf"=>"51", "unique-ip"=>"2", "figure"=>"140", "scanned-summary"=>"52", "supp-data"=>"44"}
  • {"scanned-page-browse"=>"44", "month"=>"10", "cited-by"=>"1", "abstract"=>"2", "full-text"=>"2", "unique-ip"=>"5", "pdf"=>"10", "year"=>"2007", "figure"=>"123", "scanned-summary"=>"60", "supp-data"=>"60"}
  • {"month"=>"11", "scanned-page-browse"=>"47", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"0", "year"=>"2007", "pdf"=>"48", "unique-ip"=>"9", "figure"=>"177", "scanned-summary"=>"72", "supp-data"=>"63"}
  • {"scanned-page-browse"=>"42", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "unique-ip"=>"14", "pdf"=>"17", "year"=>"2007", "figure"=>"139", "scanned-summary"=>"63", "supp-data"=>"66"}
  • {"month"=>"1", "scanned-page-browse"=>"37", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"2", "year"=>"2008", "pdf"=>"4", "unique-ip"=>"1", "figure"=>"88", "scanned-summary"=>"43", "supp-data"=>"55"}
  • {"scanned-page-browse"=>"43", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"3", "pdf"=>"4", "year"=>"2008", "figure"=>"108", "scanned-summary"=>"58", "supp-data"=>"54"}
  • {"month"=>"3", "scanned-page-browse"=>"30", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "year"=>"2008", "pdf"=>"17", "unique-ip"=>"1", "figure"=>"102", "scanned-summary"=>"46", "supp-data"=>"44"}
  • {"scanned-page-browse"=>"35", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "unique-ip"=>"5", "pdf"=>"31", "year"=>"2008", "figure"=>"133", "scanned-summary"=>"62", "supp-data"=>"54"}
  • {"month"=>"5", "scanned-page-browse"=>"17", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"1", "year"=>"2008", "pdf"=>"97", "unique-ip"=>"6", "figure"=>"155", "scanned-summary"=>"32", "supp-data"=>"32"}
  • {"scanned-page-browse"=>"16", "month"=>"6", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"1", "unique-ip"=>"2", "pdf"=>"15", "year"=>"2008", "figure"=>"58", "scanned-summary"=>"20", "supp-data"=>"24"}
  • {"month"=>"7", "scanned-page-browse"=>"16", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"0", "year"=>"2008", "pdf"=>"4", "unique-ip"=>"0", "figure"=>"44", "scanned-summary"=>"24", "supp-data"=>"23"}
  • {"scanned-page-browse"=>"30", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"1", "unique-ip"=>"3", "pdf"=>"10", "year"=>"2008", "figure"=>"82", "scanned-summary"=>"38", "supp-data"=>"37"}
  • {"month"=>"9", "scanned-page-browse"=>"25", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2008", "pdf"=>"6", "unique-ip"=>"6", "figure"=>"77", "scanned-summary"=>"36", "supp-data"=>"34"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"30", "unique-ip"=>"29", "pdf"=>"19", "year"=>"2008", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"36"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"34", "year"=>"2008", "pdf"=>"19", "unique-ip"=>"31", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"77"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"2", "abstract"=>"2", "full-text"=>"22", "unique-ip"=>"29", "pdf"=>"21", "year"=>"2008", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"27", "year"=>"2009", "pdf"=>"19", "unique-ip"=>"30", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"35", "unique-ip"=>"32", "pdf"=>"24", "year"=>"2009", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"17"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"2", "abstract"=>"3", "full-text"=>"57", "year"=>"2009", "pdf"=>"26", "unique-ip"=>"49", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"49"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"42", "unique-ip"=>"29", "pdf"=>"52", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"58", "year"=>"2009", "pdf"=>"40", "unique-ip"=>"43", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"14"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"59", "unique-ip"=>"29", "pdf"=>"50", "year"=>"2009", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"31"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"52", "year"=>"2009", "pdf"=>"43", "unique-ip"=>"26", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"35"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"25", "unique-ip"=>"25", "pdf"=>"15", "year"=>"2009", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"13"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"48", "year"=>"2009", "pdf"=>"30", "unique-ip"=>"25", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"32", "unique-ip"=>"22", "pdf"=>"26", "year"=>"2009", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"6"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"36", "year"=>"2009", "pdf"=>"26", "unique-ip"=>"34", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"34", "unique-ip"=>"33", "pdf"=>"16", "year"=>"2009", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"20", "year"=>"2012", "pdf"=>"11", "unique-ip"=>"24", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"unique-ip"=>"29", "full-text"=>"33", "pdf"=>"12", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"19", "full-text"=>"20", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"37", "full-text"=>"32", "pdf"=>"12", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"40", "full-text"=>"56", "pdf"=>"28", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"47", "full-text"=>"51", "pdf"=>"15", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"26", "full-text"=>"24", "pdf"=>"13", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"44", "full-text"=>"43", "pdf"=>"27", "abstract"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"25", "full-text"=>"31", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"34", "full-text"=>"41", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"35", "full-text"=>"31", "pdf"=>"17", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"25", "full-text"=>"25", "pdf"=>"16", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"14", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"28", "full-text"=>"37", "pdf"=>"20", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"32", "full-text"=>"37", "pdf"=>"17", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"40", "full-text"=>"43", "pdf"=>"25", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"51", "full-text"=>"57", "pdf"=>"21", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"36", "full-text"=>"43", "pdf"=>"13", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"49", "full-text"=>"50", "pdf"=>"18", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"38", "full-text"=>"37", "pdf"=>"11", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"3", "cited-by"=>"4", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"43", "full-text"=>"43", "pdf"=>"16", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"49", "full-text"=>"63", "pdf"=>"17", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"33", "full-text"=>"38", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"47", "full-text"=>"46", "pdf"=>"30", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"84", "full-text"=>"57", "pdf"=>"25", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"32", "cited-by"=>"1", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"54", "full-text"=>"43", "pdf"=>"14", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"29", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"75", "full-text"=>"72", "pdf"=>"32", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"30", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"61", "full-text"=>"71", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"23", "cited-by"=>"1", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"100", "full-text"=>"94", "pdf"=>"38", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"47", "supp-data"=>"26", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"57", "full-text"=>"60", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"10", "cited-by"=>"2", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"69", "full-text"=>"63", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"25", "supp-data"=>"23", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"59", "full-text"=>"66", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"21", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"82", "full-text"=>"80", "pdf"=>"36", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"18", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"66", "full-text"=>"81", "pdf"=>"22", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"73", "full-text"=>"67", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"25", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"84", "full-text"=>"90", "pdf"=>"24", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"18", "cited-by"=>"6", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"30", "full-text"=>"31", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"54", "full-text"=>"58", "pdf"=>"29", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"58", "full-text"=>"59", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"5", "cited-by"=>"1", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"55", "full-text"=>"62", "pdf"=>"24", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"84", "full-text"=>"75", "pdf"=>"38", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"45", "cited-by"=>"24", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"42", "full-text"=>"36", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"56", "full-text"=>"59", "pdf"=>"27", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"27", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"60", "full-text"=>"43", "pdf"=>"36", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"12", "cited-by"=>"1", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"67", "full-text"=>"85", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"18", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"66", "full-text"=>"76", "pdf"=>"28", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"27", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"45", "full-text"=>"54", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"60", "full-text"=>"81", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"38", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"45", "full-text"=>"42", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"31", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"50", "full-text"=>"59", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"19", "cited-by"=>"4", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"48", "full-text"=>"61", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"16", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"57", "full-text"=>"68", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"31", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"75", "full-text"=>"84", "pdf"=>"22", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"26", "supp-data"=>"17", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"51", "full-text"=>"52", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"46", "full-text"=>"40", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"12", "cited-by"=>"27", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"71", "full-text"=>"87", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"22", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"88", "full-text"=>"91", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"31", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"54", "full-text"=>"66", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"55", "full-text"=>"60", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"50", "full-text"=>"50", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"44", "full-text"=>"51", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"47", "full-text"=>"50", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"48", "full-text"=>"58", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"73", "full-text"=>"81", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"42", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"74", "full-text"=>"95", "pdf"=>"21", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"13", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"50", "full-text"=>"49", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"52", "full-text"=>"59", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"70", "full-text"=>"73", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"44", "full-text"=>"50", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"20", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"41", "full-text"=>"48", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"57", "full-text"=>"64", "pdf"=>"12", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"61", "full-text"=>"71", "pdf"=>"14", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"47", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"49", "full-text"=>"45", "pdf"=>"13", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"39", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"58", "full-text"=>"65", "pdf"=>"14", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"54", "full-text"=>"57", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"59", "full-text"=>"59", "pdf"=>"13", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"87", "full-text"=>"96", "pdf"=>"23", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"42", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"56", "full-text"=>"50", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"48", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"62", "full-text"=>"63", "pdf"=>"16", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"5", "cited-by"=>"32", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"62", "full-text"=>"66", "pdf"=>"26", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"32", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"63", "full-text"=>"67", "pdf"=>"15", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"75", "full-text"=>"81", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"50", "full-text"=>"55", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"58", "full-text"=>"64", "pdf"=>"18", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"10", "cited-by"=>"1", "year"=>"2019", "month"=>"9"}

Relative Metric

{"start_date"=>"2006-01-01T00:00:00Z", "end_date"=>"2006-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[297, 950, 1258, 1471, 1611, 1717, 1818, 1905, 1988, 2074, 2148, 2220, 2272, 2329, 2392, 2437, 2475, 2527, 2606, 2656, 2729, 2792, 2864, 2922, 2984, 3036, 3093, 3147, 3215, 3295, 3385, 3458, 3534, 3586, 3651, 3691, 3739, 3774, 3838, 3892, 3953, 4006, 4091, 4153, 4218, 4284, 4348, 4394, 4439, 4497, 4540, 4599, 4643, 4697, 4742, 4798, 4847, 4887, 4933, 4983, 5015, 5043, 5088, 5131, 5194, 5251, 5314, 5377, 5424, 5478, 5550, 5625, 5702, 5758, 5841, 5921, 6038, 6102, 6190, 6288, 6368, 6475, 6557, 6601, 6685, 6762, 6861, 6903, 7017, 7075, 7132, 7198, 7314, 7361, 7426, 7532, 7554]}, {"subject_area"=>"/Biology and life sciences/Computational biology", "average_usage"=>[257, 781, 1101, 1362, 1548, 1610, 1718, 1857, 1935, 2025, 2098, 2165, 2229, 2268, 2317, 2372, 2438, 2499, 2560, 2616, 2665, 2750, 2842, 2902, 2957, 3019, 3060, 3109, 3160, 3226, 3313, 3394, 3445, 3516, 3547, 3631, 3680, 3717, 3761, 3803, 3848, 3888, 3924, 3976, 4032, 4068, 4134, 4224, 4264, 4305, 4348, 4396, 4447, 4499, 4530, 4568, 4607, 4640, 4685, 4731, 4779, 4828, 4893, 4960, 5039, 5093, 5142, 5189, 5247, 5283, 5325, 5376, 5447, 5508, 5544, 5576, 5627, 5665, 5789, 5888, 5990, 6040, 6145, 6202, 6273, 6348, 6418, 6498, 6623, 6718, 6826, 6919, 7123, 7215, 7279, 7336, 7386]}, {"subject_area"=>"/Biology and life sciences/Molecular biology", "average_usage"=>[236, 854, 1188, 1488, 1640, 1742, 1827, 1909, 1998, 2104, 2191, 2266, 2323, 2383, 2438, 2491, 2520, 2558, 2619, 2681, 2760, 2833, 2897, 2991, 3065, 3120, 3193, 3259, 3308, 3361, 3452, 3528, 3567, 3623, 3677, 3735, 3764, 3824, 3890, 3978, 4014, 4058, 4139, 4181, 4227, 4300, 4346, 4429, 4483, 4530, 4588, 4629, 4690, 4740, 4789, 4832, 4863, 4908, 4949, 4986, 5025, 5058, 5105, 5134, 5200, 5268, 5324, 5372, 5419, 5486, 5549, 5598, 5655, 5712, 5818, 5861, 5917, 5991, 6101, 6210, 6321, 6447, 6555, 6622, 6691, 6771, 6863, 6972, 7096, 7210, 7273, 7367, 7453, 7518, 7595, 7642, 7737]}]}

F1000Prime | Further Information

Loading … Spinner
There are currently no alerts