mixOmics: An R package for ‘omics feature selection and multiple data integration
Publication Date
November 03, 2017
Authors
Florian Rohart, Benoît Gautier, Amrit Singh & Kim Anh Lê Cao
Volume
13
Issue
11
Pages
e1005752
DOI
https://dx.plos.org/10.1371/journal.pcbi.1005752
Publisher URL
http://journals.plos.org/ploscompbiol/article?id=10.1371%2Fjournal.pcbi.1005752
Web of Science
94
Scopus
85036524587
Mendeley
http://www.mendeley.com/research/mixomics-r-package-omics-feature-selection-multiple-data-integration-8
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"mixOmics: An R package for ‘omics feature selection and multiple data integration", "type"=>"journal", "authors"=>[{"first_name"=>"Florian", "last_name"=>"Rohart"}, {"first_name"=>"Benoît", "last_name"=>"Gautier"}, {"first_name"=>"Amrit", "last_name"=>"Singh"}, {"first_name"=>"Kim-Anh", "last_name"=>"Lê Cao"}], "year"=>2017, "source"=>"PLOS Computational Biology", "identifiers"=>{"doi"=>"10.1371/journal.pcbi.1005752", "isbn"=>"1111111111", "pmid"=>"29099853", "issn"=>"1553-7358"}, "id"=>"c7b0ce1c-2c3a-3909-a91b-74305609d4e9", "abstract"=>"The advent of high throughput technologies has led to a wealth of publicly available ‘omics data coming from different sources, such as transcriptomics, proteomics, metabolomics. Combining such large-scale biological data sets can lead to the discovery of important biological insights, provided that relevant information can be extracted in a holistic manner. Current statistical approaches have been focusing on identifying small subsets of molecules (a ‘molecular signature’) to explain or predict biological conditions, but mainly for a single type of ‘omics. In addition, commonly used methods are univariate and consider each biological feature independently. We introduce mixOmics, an R package dedicated to the multivariate analysis of biological data sets with a specific focus on data exploration, dimension reduction and visualisation. By adopting a systems biology approach, the toolkit provides a wide range of methods that statistically integrate several data sets at once to probe relationships between heterogeneous ‘omics data sets. Our recent methods extend Projection to Latent Structure (PLS) models for discriminant analysis, for data integration across multiple ‘omics data or across independent studies, and for the identification of molecular signatures. We illustrate our latest mixOmics integrative frameworks for the multivariate analyses of ‘omics data available from the package.", "link"=>"http://www.mendeley.com/research/mixomics-r-package-omics-feature-selection-multiple-data-integration-8", "reader_count"=>99, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>2, "Researcher"=>32, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>25, "Student > Postgraduate"=>1, "Student > Master"=>14, "Other"=>3, "Student > Bachelor"=>9, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>5, "Professor > Associate Professor"=>2, "Researcher"=>32, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>25, "Student > Postgraduate"=>1, "Student > Master"=>14, "Other"=>3, "Student > Bachelor"=>9, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>9, "Engineering"=>3, "Environmental Science"=>2, "Biochemistry, Genetics and Molecular Biology"=>26, "Mathematics"=>6, "Agricultural and Biological Sciences"=>37, "Medicine and Dentistry"=>1, "Neuroscience"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>2, "Chemistry"=>3, "Computer Science"=>8}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>3}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Neuroscience"=>{"Neuroscience"=>2}, "Chemistry"=>{"Chemistry"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>37}, "Computer Science"=>{"Computer Science"=>8}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>26}, "Mathematics"=>{"Mathematics"=>6}, "Unspecified"=>{"Unspecified"=>9}, "Environmental Science"=>{"Environmental Science"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>2}}, "group_count"=>8}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85036524587"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85036524587?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85036524587&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85036524587&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/85036524587", "dc:identifier"=>"SCOPUS_ID:85036524587", "eid"=>"2-s2.0-85036524587", "dc:title"=>"mixOmics: An R package for ‘omics feature selection and multiple data integration", "dc:creator"=>"Rohart F.", "prism:publicationName"=>"PLoS Computational Biology", "prism:issn"=>"1553734X", "prism:eIssn"=>"15537358", "prism:volume"=>"13", "prism:issueIdentifier"=>"11", "prism:pageRange"=>nil, "prism:coverDate"=>"2017-11-01", "prism:coverDisplayDate"=>"November 2017", "prism:doi"=>"10.1371/journal.pcbi.1005752", "citedby-count"=>"132", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Queensland", "affiliation-city"=>"Brisbane", "affiliation-country"=>"Australia"}], "pubmed-id"=>"29099853", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1005752", "source-id"=>"4000151810", "openaccess"=>"1", "openaccessFlag"=>true}

Twitter

Counter

  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"632", "xml_views"=>"34", "html_views"=>"4485"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"318", "xml_views"=>"6", "html_views"=>"1636"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"406", "xml_views"=>"0", "html_views"=>"967"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"357", "xml_views"=>"1", "html_views"=>"670"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"343", "xml_views"=>"2", "html_views"=>"635"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"270", "xml_views"=>"0", "html_views"=>"421"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"259", "xml_views"=>"0", "html_views"=>"540"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"244", "xml_views"=>"2", "html_views"=>"491"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"272", "xml_views"=>"6", "html_views"=>"430"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"257", "xml_views"=>"1", "html_views"=>"405"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"291", "xml_views"=>"2", "html_views"=>"448"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"263", "xml_views"=>"7", "html_views"=>"519"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"282", "xml_views"=>"1", "html_views"=>"514"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"256", "xml_views"=>"0", "html_views"=>"388"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"284", "xml_views"=>"3", "html_views"=>"480"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"287", "xml_views"=>"1", "html_views"=>"428"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"294", "xml_views"=>"7", "html_views"=>"482"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"296", "xml_views"=>"1", "html_views"=>"497"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"318", "xml_views"=>"4", "html_views"=>"496"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"274", "xml_views"=>"2", "html_views"=>"420"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"333", "xml_views"=>"1", "html_views"=>"485"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"192", "xml_views"=>"0", "html_views"=>"303"}

PMC Usage Stats

  • {"unique-ip"=>"57", "full-text"=>"45", "pdf"=>"30", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"26", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"84", "full-text"=>"75", "pdf"=>"40", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"31", "supp-data"=>"9", "cited-by"=>"1", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"71", "full-text"=>"76", "pdf"=>"35", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"31", "supp-data"=>"4", "cited-by"=>"1", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"59", "full-text"=>"68", "pdf"=>"10", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"7", "cited-by"=>"1", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"86", "full-text"=>"85", "pdf"=>"20", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"32", "supp-data"=>"6", "cited-by"=>"3", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"73", "full-text"=>"72", "pdf"=>"30", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"25", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"57", "full-text"=>"56", "pdf"=>"25", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"80", "full-text"=>"95", "pdf"=>"20", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"70", "full-text"=>"72", "pdf"=>"18", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"76", "full-text"=>"89", "pdf"=>"17", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"76", "full-text"=>"94", "pdf"=>"24", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"85", "full-text"=>"101", "pdf"=>"27", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"68", "full-text"=>"70", "pdf"=>"16", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"5", "cited-by"=>"1", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"104", "full-text"=>"101", "pdf"=>"19", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"28", "supp-data"=>"9", "cited-by"=>"5", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"88", "full-text"=>"87", "pdf"=>"25", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"8", "cited-by"=>"10", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"73", "full-text"=>"76", "pdf"=>"25", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"22", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"100", "full-text"=>"108", "pdf"=>"18", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"10", "cited-by"=>"3", "year"=>"2019", "month"=>"5"}

F1000Prime | Further Information

Loading … Spinner
There are currently no alerts