Classical Genetics Meets Next-Generation Sequencing: Uncovering a Genome-Wide Recombination Map in Drosophila melanogaster
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{"title"=>"Classical Genetics Meets Next-Generation Sequencing: Uncovering a Genome-Wide Recombination Map in Drosophila melanogaster", "type"=>"journal", "authors"=>[{"first_name"=>"Nadia D.", "last_name"=>"Singh", "scopus_author_id"=>"8986145600"}], "year"=>2012, "source"=>"PLoS Genetics", "identifiers"=>{"sgr"=>"84868130693", "doi"=>"10.1371/journal.pgen.1003024", "pui"=>"365953622", "pmid"=>"25954717", "scopus"=>"2-s2.0-84868130693", "issn"=>"15537390", "isbn"=>"1553-7404 (Electronic)"}, "id"=>"e5444a0f-3d69-3b3a-9d19-8ccab0d3944f", "abstract"=>"What responsibility do scientists have to report the experimental work and analyses they do on animals fully and transparently, and what responsibilities do funders, journal editors, and reviewers have to ensure that what is reported is done so appropriately? While the answer to both of these questions might seem obvious, the accumulating evidence suggests that the actual reporting done in publications is far from ideal. As Baker et al. discuss in this issue of PLOS Biology [1], 86%–87% of experimental articles do not give any indication that the animals in the study were properly randomized, and 95% do not demonstrate that their study had a sample size sufficient to detect an effect of the treatment were there to be one [2,3]. Moreover, they show that 13% of studies of rodents with experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) failed to report any statistical analyses at all, and 55% included inappropriate statistics [1]. And while you might expect that publications in ‘‘higher ranked’’ journals would have better reporting and a more rigorous methodology, Baker et al. reveal that higher ranked journals (with an impact factor greater than ten) are twice as likely to report either no or inappropriate statistics.", "link"=>"http://www.mendeley.com/research/classical-genetics-meets-nextgeneration-sequencing-uncovering-genomewide-recombination-map-drosophil", "reader_count"=>45, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>7, "Researcher"=>18, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>9, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>1, "Student > Bachelor"=>2, "Professor"=>5}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>7, "Researcher"=>18, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>9, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>1, "Student > Bachelor"=>2, "Professor"=>5}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Biochemistry, Genetics and Molecular Biology"=>7, "Agricultural and Biological Sciences"=>34, "Medicine and Dentistry"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>2}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>34}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>7}, "Unspecified"=>{"Unspecified"=>2}}, "reader_count_by_country"=>{"Netherlands"=>1, "Belgium"=>1, "United States"=>2, "Brazil"=>1, "United Kingdom"=>1, "South Africa"=>1, "France"=>1, "Germany"=>1, "Spain"=>2}, "group_count"=>2}

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Relative Metric

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