Human Social Genomics
- Publication Date
- August 28, 2014
- Journal
- PLOS Genetics
- Author
- Steven W. Cole
- Volume
- 10
- Issue
- 8
- Pages
- e1004601
- DOI
- https://dx.plos.org/10.1371/journal.pgen.1004601
- Publisher URL
- http://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1004601
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/25166010
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148225
- Europe PMC
- http://europepmc.org/abstract/MED/25166010
- Web of Science
- 000341577800058
- Scopus
- 84919365614
- Mendeley
- http://www.mendeley.com/research/human-social-genomics
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Mendeley | Further Information
{"title"=>"Human Social Genomics", "type"=>"journal", "authors"=>[{"first_name"=>"Steven W.", "last_name"=>"Cole", "scopus_author_id"=>"55237592900"}], "year"=>2014, "source"=>"PLoS Genetics", "identifiers"=>{"doi"=>"10.1371/journal.pgen.1004601", "sgr"=>"84919365614", "issn"=>"15537404", "pui"=>"607916905", "isbn"=>"1553-7404 (Electronic)\\r1553-7390 (Linking)", "pmid"=>"25166010", "scopus"=>"2-s2.0-84919365614"}, "id"=>"d4dc6c8c-5b9f-3380-8b43-6ce4a005a50a", "abstract"=>"A growing literature in human social genomics has begun to analyze how everyday life circumstances influence human gene expression. Social-environmental conditions such as urbanity, low socioeconomic status, social isolation, social threat, and low or unstable social status have been found to associate with differential expression of hundreds of gene transcripts in leukocytes and diseased tissues such as metastatic cancers. In leukocytes, diverse types of social adversity evoke a common conserved transcriptional response to adversity (CTRA) characterized by increased expression of proinflammatory genes and decreased expression of genes involved in innate antiviral responses and antibody synthesis. Mechanistic analyses have mapped the neural \"social signal transduction\" pathways that stimulate CTRA gene expression in response to social threat and may contribute to social gradients in health. Research has also begun to analyze the functional genomics of optimal health and thriving. Two emerging opportunities now stand to revolutionize our understanding of the everyday life of the human genome: network genomics analyses examining how systems-level capabilities emerge from groups of individual socially sensitive genomes and near-real-time transcriptional biofeedback to empirically optimize individual well-being in the context of the unique genetic, geographic, historical, developmental, and social contexts that jointly shape the transcriptional realization of our innate human genomic potential for thriving.", "link"=>"http://www.mendeley.com/research/human-social-genomics", "reader_count"=>150, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>10, "Student > Doctoral Student"=>11, "Researcher"=>25, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>11, "Student > Master"=>15, "Other"=>4, "Student > Bachelor"=>12, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>14}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>10, "Student > Doctoral Student"=>11, "Researcher"=>25, "Student > Ph. D. Student"=>43, "Student > Postgraduate"=>11, "Student > Master"=>15, "Other"=>4, "Student > Bachelor"=>12, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>14}, "reader_count_by_subject_area"=>{"Unspecified"=>10, "Agricultural and Biological Sciences"=>42, "Arts and Humanities"=>2, "Business, Management and Accounting"=>1, "Chemistry"=>2, "Computer Science"=>1, "Economics, Econometrics and Finance"=>1, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>9, "Nursing and Health Professions"=>2, "Medicine and Dentistry"=>18, "Neuroscience"=>5, "Psychology"=>39, "Social Sciences"=>16, "Linguistics"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>18}, "Social Sciences"=>{"Social Sciences"=>16}, "Psychology"=>{"Psychology"=>39}, "Unspecified"=>{"Unspecified"=>10}, "Environmental Science"=>{"Environmental Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>2}, "Chemistry"=>{"Chemistry"=>2}, "Neuroscience"=>{"Neuroscience"=>5}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>42}, "Computer Science"=>{"Computer Science"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Linguistics"=>{"Linguistics"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>9}}, "reader_count_by_country"=>{"Netherlands"=>1, "United States"=>2, "Taiwan"=>1, "Italy"=>2, "United Kingdom"=>1, "Chile"=>1, "Peru"=>1, "Spain"=>1}, "group_count"=>3}CrossRef
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Scopus | Further Information
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- {"id"=>"512536583556579328", "text"=>"Human Social Genomics http://t.co/q3mHUH5brJ", "created_at"=>"2014-09-18T09:40:18Z", "user"=>"LeucineRichBio", "user_name"=>"Leucine Rich Bio", "user_profile_image"=>"http://pbs.twimg.com/profile_images/378800000278863237/334998dd45c047cddc24b410c5f81c57_normal.png"}
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- {"id"=>"512833596973776896", "text"=>"@leonidkruglyak @dgmacarthur I think this one is better http://t.co/IBXc2OAEJR", "created_at"=>"2014-09-19T05:20:32Z", "user"=>"dahinds", "user_name"=>"David Hinds", "user_profile_image"=>"http://abs.twimg.com/sticky/default_profile_images/default_profile_4_normal.png"}
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- {"id"=>"514126975557173249", "text"=>"social genomics: systems-level response emerge in groups & their individual socioeconoimic sensitive genomes http://t.co/Jv5tvPluYF", "created_at"=>"2014-09-22T18:59:57Z", "user"=>"LussierY", "user_name"=>"Prof. Yves Lussier", "user_profile_image"=>"http://pbs.twimg.com/profile_images/494365134945398786/kn6gdHKB_normal.jpeg"}
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- {"id"=>"521256405895233537", "text"=>"Growing literature in social genomics has begun to analyze how everyday life circumstances influence gene expression http://t.co/NejdojhCPj", "created_at"=>"2014-10-12T11:09:46Z", "user"=>"MrEnkapsis", "user_name"=>"Sebastian", "user_profile_image"=>"http://pbs.twimg.com/profile_images/512579897445720064/ZZx6XVWa_normal.jpeg"}
- {"id"=>"742842990515879936", "text"=>"Human Social Genomics, by Steven Cole: https://t.co/m4LhToFZPB https://t.co/c04HvgeaT1", "created_at"=>"2016-06-14T22:15:44Z", "user"=>"AmygdaIae", "user_name"=>"Xain", "user_profile_image"=>"http://pbs.twimg.com/profile_images/731125072048586752/McN-Fpmb_normal.jpg"}
- {"id"=>"742844815692423168", "text"=>"RT @AmygdaIae: Human Social Genomics, by Steven Cole: https://t.co/m4LhToFZPB https://t.co/c04HvgeaT1", "created_at"=>"2016-06-14T22:23:00Z", "user"=>"dreadyvet", "user_name"=>"Fabian G. B. Rivers", "user_profile_image"=>"http://pbs.twimg.com/profile_images/739106084653309952/_7zZ3dPk_normal.jpg"}
- {"id"=>"742845706306785280", "text"=>"RT @AmygdaIae: Human Social Genomics, by Steven Cole: https://t.co/m4LhToFZPB https://t.co/c04HvgeaT1", "created_at"=>"2016-06-14T22:26:32Z", "user"=>"aiquena", "user_name"=>"so elle", "user_profile_image"=>"http://pbs.twimg.com/profile_images/675729636647653376/YypLUgiV_normal.jpg"}
- {"id"=>"742898159177850880", "text"=>"RT @AmygdaIae: Human Social Genomics, by Steven Cole: https://t.co/m4LhToFZPB https://t.co/c04HvgeaT1", "created_at"=>"2016-06-15T01:54:58Z", "user"=>"darthton", "user_name"=>"Anikulapo", "user_profile_image"=>"http://pbs.twimg.com/profile_images/736140366521487360/3QgCqB5f_normal.jpg"}
- {"id"=>"753057274990440448", "text"=>"FYI the Steven Cole (2014) paper is free on PLoS One https://t.co/yQYSR1k3Mt", "created_at"=>"2016-07-13T02:43:40Z", "user"=>"They_berian", "user_name"=>"Kwame Taught Me", "user_profile_image"=>"http://pbs.twimg.com/profile_images/749732464793378817/z3_Mte1w_normal.jpg"}
- {"id"=>"753060350061260801", "text"=>"RT @They_berian: FYI the Steven Cole (2014) paper is free on PLoS One https://t.co/yQYSR1k3Mt", "created_at"=>"2016-07-13T02:55:53Z", "user"=>"djenne", "user_name"=>"djenne", "user_profile_image"=>"http://pbs.twimg.com/profile_images/68334735/2887015916_normal.jpg"}
- {"id"=>"753095779108196352", "text"=>"RT @They_berian: FYI the Steven Cole (2014) paper is free on PLoS One https://t.co/yQYSR1k3Mt", "created_at"=>"2016-07-13T05:16:40Z", "user"=>"SitaraStuff", "user_name"=>"Kid A", "user_profile_image"=>"http://pbs.twimg.com/profile_images/645708345479839745/g3hbdsq6_normal.jpg"}
- {"id"=>"791741662615568384", "text"=>"RT @Hood_Biologist: FYI the Steven Cole (2014) paper is free on PLoS One https://t.co/yQYSR1k3Mt", "created_at"=>"2016-10-27T20:41:36Z", "user"=>"eruzlie", "user_name"=>"Young Goldie", "user_profile_image"=>"http://pbs.twimg.com/profile_images/785932223471955969/fGTIwwB0_normal.jpg"}
- {"id"=>"802538725913796608", "text"=>"How social factors effect genes: https://t.co/1IeZlieBbL", "created_at"=>"2016-11-26T15:45:17Z", "user"=>"DrLoBisco", "user_name"=>"Dr. LoBisco", "user_profile_image"=>"http://pbs.twimg.com/profile_images/692540891131691008/q39jpOXM_normal.jpg"}
- {"id"=>"806709318288408576", "text"=>"Steve Cole: Human Social Genomics - why our previously adaptive biological responses now cause harm https://t.co/zlO4bUEc8m #icbm2016", "created_at"=>"2016-12-08T03:57:44Z", "user"=>"hagsie", "user_name"=>"Haryana Dhillon", "user_profile_image"=>"http://pbs.twimg.com/profile_images/762165895590322176/UFzOqh5e_normal.jpg"}
- {"id"=>"806709561591615488", "text"=>"RT @hagsie: Steve Cole: Human Social Genomics - why our previously adaptive biological responses now cause harm https://t.co/zlO4bUEc8m #ic…", "created_at"=>"2016-12-08T03:58:42Z", "user"=>"HigginsRosemary", "user_name"=>"AProfRosemaryHiggins", "user_profile_image"=>"http://pbs.twimg.com/profile_images/586999310979432450/1YtAxI0d_normal.jpg"}
- {"id"=>"806713138225655808", "text"=>"RT @hagsie: Steve Cole: Human Social Genomics - why our previously adaptive biological responses now cause harm https://t.co/zlO4bUEc8m #ic…", "created_at"=>"2016-12-08T04:12:54Z", "user"=>"carissa_bon", "user_name"=>"Carissa Bonner", "user_profile_image"=>"http://pbs.twimg.com/profile_images/472149108975620096/Rm-OSnB1_normal.jpeg"}
- {"id"=>"812757502681083904", "text"=>"One place where sociology meets biology: social genomics https://t.co/ZO9Bb1iLBP https://t.co/vqsbh8whbU", "created_at"=>"2016-12-24T20:31:03Z", "user"=>"jw_627", "user_name"=>"Johnny?", "user_profile_image"=>"http://pbs.twimg.com/profile_images/808750855696556032/ANgEMuzE_normal.jpg"}
- {"id"=>"844941716788523008", "text"=>"#EvidenceBasedPolicy grounded in #PositivePsychology: \"Molecular indicators of human wellbeing add a new... https://t.co/EZwbYn6zXf", "created_at"=>"2017-03-23T15:59:38Z", "user"=>"PositivityMtrs", "user_name"=>"Positivity Matters", "user_profile_image"=>"http://pbs.twimg.com/profile_images/843474314762641408/7h3eW6mj_normal.jpg"}
- {"id"=>"845268787171639296", "text"=>"About \" how everyday life circumstances #influence human #gene expression:\"\nhttps://t.co/9zQFOn1q67", "created_at"=>"2017-03-24T13:39:17Z", "user"=>"daria_pirvu", "user_name"=>"Daria Pirvu", "user_profile_image"=>"http://pbs.twimg.com/profile_images/799944153991958528/Y5sdifql_normal.jpg"}
- {"id"=>"860053119039877121", "text"=>"Everyday life circumstances influence gene expression.https://t.co/7NPc4uro5Z", "created_at"=>"2017-05-04T08:46:57Z", "user"=>"HawkmoonHEMS", "user_name"=>"brian burns", "user_profile_image"=>"http://pbs.twimg.com/profile_images/2345655275/1xpkt3a9gigpbafy7wgh_normal.jpeg"}
- {"id"=>"860078076662657025", "text"=>"RT @HawkmoonHEMS: Everyday life circumstances influence gene expression.https://t.co/7NPc4uro5Z", "created_at"=>"2017-05-04T10:26:07Z", "user"=>"SLBaldry", "user_name"=>"Sascha Baldry", "user_profile_image"=>"http://pbs.twimg.com/profile_images/815345346578522112/LLTM-Kqc_normal.jpg"}
Wikipedia | Further Information
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Counter
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PMC Usage Stats | Further Information
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Relative Metric
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