Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees
Publication Date
May 25, 2017
Authors
Andreas Wallberg, Caspar Schöning, Matthew T. Webster & Martin Hasselmann
Volume
13
Issue
5
Pages
e1006792
DOI
https://dx.plos.org/10.1371/journal.pgen.1006792
Publisher URL
http://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1006792
Scopus
85020167392
Mendeley
http://www.mendeley.com/research/two-extended-haplotype-blocks-associated-adaptation-high-altitude-habitats-east-african-honey-bees
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees", "type"=>"journal", "authors"=>[{"first_name"=>"Andreas", "last_name"=>"Wallberg", "scopus_author_id"=>"36912240600"}, {"first_name"=>"Caspar", "last_name"=>"Schöning", "scopus_author_id"=>"8586142000"}, {"first_name"=>"Matthew T.", "last_name"=>"Webster", "scopus_author_id"=>"7202299046"}, {"first_name"=>"Martin", "last_name"=>"Hasselmann", "scopus_author_id"=>"56187651600"}], "year"=>2017, "source"=>"PLoS Genetics", "identifiers"=>{"sgr"=>"85020167392", "pmid"=>"28542163", "pui"=>"616626815", "issn"=>"15537404", "isbn"=>"1111111111", "scopus"=>"2-s2.0-85020167392", "doi"=>"10.1371/journal.pgen.1006792"}, "id"=>"46463343-64d6-3fff-89ee-cdcd0fd5c3e7", "abstract"=>"Understanding the genetic basis of adaption is a central task in biology. Populations of the honey bee Apis mellifera that inhabit the mountain forests of East Africa differ in behavior and morphology from those inhabiting the surrounding lowland savannahs, which likely reflects adaptation to these habitats. We performed whole genome sequencing on 39 samples of highland and lowland bees from two pairs of populations to determine their evolutionary affinities and identify the genetic basis of these putative adaptations. We find that in general, levels of genetic differentiation between highland and lowland populations are very low, consistent with them being a single panmictic population. However, we identify two loci on chromosomes 7 and 9, each several hundred kilobases in length, which exhibit near fixation for different haplotypes between highland and lowland populations. The highland haplotypes at these loci are extremely rare in samples from the rest of the world. Patterns of segregation of genetic variants suggest that recombination between haplotypes at each locus is suppressed, indicating that they comprise independent structural variants. The haplotype on chromosome 7 harbors nearly all octopamine receptor genes in the honey bee genome. These have a role in learning and foraging behavior in honey bees and are strong candidates for adaptation to highland habitats. Molecular analysis of a putative breakpoint indicates that it may disrupt the coding sequence of one of these genes. Divergence between the highland and lowland haplotypes at both loci is extremely high suggesting that they are ancient balanced polymorphisms that greatly predate divergence between the extant honey bee subspecies.", "link"=>"http://www.mendeley.com/research/two-extended-haplotype-blocks-associated-adaptation-high-altitude-habitats-east-african-honey-bees", "reader_count"=>42, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>5, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>5, "Student > Master"=>5, "Other"=>2, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>5, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>5, "Student > Master"=>5, "Other"=>2, "Student > Bachelor"=>3, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Biochemistry, Genetics and Molecular Biology"=>8, "Agricultural and Biological Sciences"=>28, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>28}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>8}, "Unspecified"=>{"Unspecified"=>5}}, "reader_count_by_country"=>{"New Zealand"=>1, "United States"=>1}, "group_count"=>2}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85020167392"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/85020167392?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85020167392&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85020167392&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/85020167392", "dc:identifier"=>"SCOPUS_ID:85020167392", "eid"=>"2-s2.0-85020167392", "dc:title"=>"Two extended haplotype blocks are associated with adaptation to high altitude habitats in East African honey bees", "dc:creator"=>"Wallberg A.", "prism:publicationName"=>"PLoS Genetics", "prism:issn"=>"15537390", "prism:eIssn"=>"15537404", "prism:volume"=>"13", "prism:issueIdentifier"=>"5", "prism:pageRange"=>nil, "prism:coverDate"=>"2017-05-01", "prism:coverDisplayDate"=>"May 2017", "prism:doi"=>"10.1371/journal.pgen.1006792", "citedby-count"=>"17", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Uppsala Universitet", "affiliation-city"=>"Uppsala", "affiliation-country"=>"Sweden"}], "pubmed-id"=>"28542163", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e1006792", "source-id"=>"4000151808", "openaccess"=>"1", "openaccessFlag"=>true}

Twitter

Counter

  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"162", "xml_views"=>"4", "html_views"=>"1265"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"149", "xml_views"=>"7", "html_views"=>"2134"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"45", "xml_views"=>"0", "html_views"=>"407"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"44", "xml_views"=>"0", "html_views"=>"486"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"35", "xml_views"=>"2", "html_views"=>"528"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"523"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"495"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"363"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"228"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"46"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"37", "xml_views"=>"2", "html_views"=>"81"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"56"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"44"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"22", "xml_views"=>"2", "html_views"=>"58"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"13", "xml_views"=>"4", "html_views"=>"38"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"16", "xml_views"=>"3", "html_views"=>"79"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"69"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"49"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"20", "xml_views"=>"2", "html_views"=>"32"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"39"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"15", "xml_views"=>"2", "html_views"=>"29"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"49"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"16", "xml_views"=>"2", "html_views"=>"25"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"41"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"16"}

PMC Usage Stats

  • {"unique-ip"=>"12", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"22", "full-text"=>"21", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"20", "full-text"=>"29", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"17", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"19", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"13", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"17", "full-text"=>"13", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"14", "full-text"=>"15", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"17", "full-text"=>"16", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
Loading … Spinner
There are currently no alerts