Smoking Cessation and Cardiovascular Disease Risk Factors: Results from the Third National Health and Nutrition Examination Survey
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{"title"=>"Smoking cessation and cardiovascular disease risk factors: Results from the third national health and nutrition examination survey", "type"=>"generic", "authors"=>[{"first_name"=>"Arvind", "last_name"=>"Bakhru", "scopus_author_id"=>"56741096900"}, {"first_name"=>"Thomas P.", "last_name"=>"Erlinger", "scopus_author_id"=>"6604072960"}], "year"=>2005, "source"=>"PLoS Medicine", "identifiers"=>{"sgr"=>"22144442811", "doi"=>"10.1371/journal.pmed.0020160", "issn"=>"15491277", "pui"=>"40973506", "isbn"=>"1549-1277", "pmid"=>"15974805", "scopus"=>"2-s2.0-22144442811"}, "id"=>"156cfb80-87ae-36a2-bf1b-628b3dc247a8", "abstract"=>"BACKGROUND Cigarette smoking is a major risk factor for the development and progression of cardiovascular disease. While smoking is associated with increased levels of inflammatory markers and accelerated atherosclerosis, few studies have examined the impact of smoking cessation on levels of inflammatory markers. The degree and rate at which inflammation subsides after smoking cessation are uncertain. It also remains unclear as to whether traditional risk factors can adequately explain the observed decline in cardiovascular risk following smoking cessation. METHODS AND FINDINGS Using data from 15,489 individuals who participated in the Third National Health and Nutrition Examination Survey (NHANES III), we analyzed the association between smoking and smoking cessation on levels of inflammatory markers and traditional cardiovascular risk factors. In particular, we examined changes in C-reactive protein, white blood cell count, albumin, and fibrinogen. Inflammatory markers demonstrated a dose-dependent and temporal relationship to smoking and smoking cessation. Both inflammatory and traditional risk factors improved with decreased intensity of smoking. With increased time since smoking cessation, inflammatory markers resolved more slowly than traditional cardiovascular risk factors. CONCLUSION Inflammatory markers may be more accurate indicators of atherosclerotic disease. Inflammatory markers returned to baseline levels 5 y after smoking cessation, consistent with the time frame associated with cardiovascular risk reduction observed in both the MONICA and Northwick Park Heart studies. Our results suggest that the inflammatory component of cardiovascular disease resulting from smoking is reversible with reduced tobacco exposure and smoking cessation.", "link"=>"http://www.mendeley.com/research/smoking-cessation-cardiovascular-disease-risk-factors-results-third-national-health-nutrition-examin-6", "reader_count"=>85, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>1, "Researcher"=>15, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>10, "Student > Master"=>17, "Other"=>5, "Student > Bachelor"=>22, "Lecturer"=>2}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>1, "Researcher"=>15, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>10, "Student > Master"=>17, "Other"=>5, "Student > Bachelor"=>22, "Lecturer"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>4, "Agricultural and Biological Sciences"=>13, "Arts and Humanities"=>1, "Business, Management and Accounting"=>1, "Engineering"=>2, "Environmental Science"=>2, "Biochemistry, Genetics and Molecular Biology"=>6, "Nursing and Health Professions"=>3, "Medicine and Dentistry"=>47, "Neuroscience"=>1, "Sports and Recreations"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Social Sciences"=>3}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>47}, "Social Sciences"=>{"Social Sciences"=>3}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Unspecified"=>{"Unspecified"=>4}, "Environmental Science"=>{"Environmental Science"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Engineering"=>{"Engineering"=>2}, "Neuroscience"=>{"Neuroscience"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>13}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>6}}, "reader_count_by_country"=>{"Sri Lanka"=>1, "Finland"=>1, "Brazil"=>1, "Switzerland"=>2, "Nepal"=>1, "Germany"=>1, "India"=>1}, "group_count"=>3}

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  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"27"}
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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/961957"], "description"=>"<p>Trends in Traditional Risk Factors with Smoking Intensity and Time since Cessation Are Given, Adjusted for Age, Sex, and Race</p>", "links"=>[], "tags"=>["smoking", "cessation", "adjusted"], "article_id"=>631949, "categories"=>["Biotechnology", "Immunology"], "users"=>["Arvind Bakhru", "Thomas P. Erlinger"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020160.g002", "stats"=>{"downloads"=>2, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Trends_in_Traditional_Risk_Factors_with_Smoking_Intensity_and_Time_since_Cessation_Are_Given_Adjusted_for_Age_Sex_and_Race_/631949", "title"=>"Trends in Traditional Risk Factors with Smoking Intensity and Time since Cessation Are Given, Adjusted for Age, Sex, and Race", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 09:00:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/961884"], "description"=>"<p>Trends in Inflammatory Markers with Smoking Intensity and Time since Cessation Are Given, Adjusted for Age, Sex, and Race</p>", "links"=>[], "tags"=>["inflammatory", "markers", "smoking", "cessation", "adjusted"], "article_id"=>631870, "categories"=>["Biotechnology", "Immunology"], "users"=>["Arvind Bakhru", "Thomas P. Erlinger"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0020160.g001", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Trends_in_Inflammatory_Markers_with_Smoking_Intensity_and_Time_since_Cessation_Are_Given_Adjusted_for_Age_Sex_and_Race_/631870", "title"=>"Trends in Inflammatory Markers with Smoking Intensity and Time since Cessation Are Given, Adjusted for Age, Sex, and Race", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 09:00:24"}

PMC Usage Stats | Further Information

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  • {"scanned-page-browse"=>"19", "month"=>"2", "cited-by"=>"3", "abstract"=>"0", "full-text"=>"10", "unique-ip"=>"0", "pdf"=>"0", "year"=>"2006", "figure"=>"76", "scanned-summary"=>"47", "supp-data"=>"44"}
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  • {"scanned-page-browse"=>"18", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"6", "pdf"=>"0", "year"=>"2006", "figure"=>"72", "scanned-summary"=>"43", "supp-data"=>"40"}
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  • {"scanned-page-browse"=>"10", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"5", "pdf"=>"0", "year"=>"2006", "figure"=>"59", "scanned-summary"=>"38", "supp-data"=>"38"}
  • {"month"=>"7", "scanned-page-browse"=>"8", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"4", "year"=>"2006", "pdf"=>"0", "unique-ip"=>"5", "figure"=>"49", "scanned-summary"=>"32", "supp-data"=>"36"}
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Relative Metric

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