The Limits of Reductionism in Medicine: Could Systems Biology Offer an Alternative?
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{"title"=>"The limits of reductionism in medicine: Could systems biology offer an alternative?", "type"=>"generic", "authors"=>[{"first_name"=>"Andrew C.", "last_name"=>"Ahn", "scopus_author_id"=>"8973462400"}, {"first_name"=>"Muneesh", "last_name"=>"Tewari", "scopus_author_id"=>"7005565238"}, {"first_name"=>"Chi Sang", "last_name"=>"Poon", "scopus_author_id"=>"7202673513"}, {"first_name"=>"Russell S.", "last_name"=>"Phillips", "scopus_author_id"=>"7404241667"}], "year"=>2006, "source"=>"PLoS Medicine", "identifiers"=>{"issn"=>"15491277", "scopus"=>"2-s2.0-33745588546", "sgr"=>"33745588546", "pui"=>"43987803", "isbn"=>"1549-1676 (Electronic)", "pmid"=>"16681415", "doi"=>"10.1371/journal.pmed.0030208"}, "id"=>"53ef0879-1ab7-30d7-bc99-1c70d710d0d0", "abstract"=>"In the first of a two part series, Ahn and colleagues discuss the reductionist approach pervading medicine and explain how a systems approach (as advocated by systems biology) may complement reductionism.", "link"=>"http://www.mendeley.com/research/limits-reductionism-medicine-systems-biology-offer-alternative", "reader_count"=>350, "reader_count_by_academic_status"=>{"Unspecified"=>6, "Professor > Associate Professor"=>26, "Librarian"=>2, "Researcher"=>78, "Student > Doctoral Student"=>11, "Student > Ph. D. Student"=>52, "Student > Postgraduate"=>13, "Student > Master"=>63, "Other"=>26, "Student > Bachelor"=>35, "Lecturer"=>9, "Lecturer > Senior Lecturer"=>7, "Professor"=>22}, "reader_count_by_user_role"=>{"Unspecified"=>6, "Professor > Associate Professor"=>26, "Librarian"=>2, "Researcher"=>78, "Student > Doctoral Student"=>11, "Student > Ph. D. Student"=>52, "Student > Postgraduate"=>13, "Student > Master"=>63, "Other"=>26, "Student > Bachelor"=>35, "Lecturer"=>9, "Lecturer > Senior Lecturer"=>7, "Professor"=>22}, "reader_count_by_subject_area"=>{"Unspecified"=>14, "Agricultural and Biological Sciences"=>103, "Philosophy"=>7, "Arts and Humanities"=>2, "Business, Management and Accounting"=>5, "Veterinary Science and Veterinary Medicine"=>1, "Chemical Engineering"=>1, "Chemistry"=>6, "Computer Science"=>14, "Engineering"=>8, "Environmental Science"=>2, "Biochemistry, Genetics and Molecular Biology"=>26, "Nursing and Health Professions"=>15, "Mathematics"=>3, "Medicine and Dentistry"=>104, "Neuroscience"=>8, "Sports and Recreations"=>3, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>5, "Psychology"=>7, "Social Sciences"=>14, "Linguistics"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>104}, "Social Sciences"=>{"Social Sciences"=>14}, "Sports and Recreations"=>{"Sports and Recreations"=>3}, "Physics and Astronomy"=>{"Physics and Astronomy"=>5}, "Psychology"=>{"Psychology"=>7}, "Mathematics"=>{"Mathematics"=>3}, "Unspecified"=>{"Unspecified"=>14}, "Environmental Science"=>{"Environmental Science"=>2}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Chemical Engineering"=>{"Chemical Engineering"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>2}, "Engineering"=>{"Engineering"=>8}, "Chemistry"=>{"Chemistry"=>6}, "Neuroscience"=>{"Neuroscience"=>8}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>103}, "Computer Science"=>{"Computer Science"=>14}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>5}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>15}, "Linguistics"=>{"Linguistics"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>26}, "Philosophy"=>{"Philosophy"=>7}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>1}}, "reader_count_by_country"=>{"Colombia"=>2, "Hong Kong"=>1, "United States"=>11, "Japan"=>1, "United Kingdom"=>12, "Switzerland"=>2, "Portugal"=>1, "India"=>1, "Spain"=>1, "New Zealand"=>1, "Canada"=>3, "Netherlands"=>2, "Turkey"=>1, "Ireland"=>1, "Brazil"=>3, "Mexico"=>2, "Italy"=>4, "South Africa"=>1, "Australia"=>1, "France"=>4, "Germany"=>3}, "group_count"=>20}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/959185"], "description"=>"<div><p>\n\t\t\t\t\t\tE. coli has been observed to migrate toward areas of higher aspartate concentrations through a series of “runs” and “tumbles” (see \n\t\t\t\t\t\t<a href=\"http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0030208#box1\" target=\"_blank\">Box 1</a>).\n\t\t\t\t\t</p>\n <p>Autophosph, autophosphorylation.</p></div>", "links"=>[], "tags"=>["biotechnology/bioengineering", "genetics and genomics", "physiology", "computational biology/systems biology", "diabetes and endocrinology", "pathology", "public health and epidemiology"], "article_id"=>629204, "categories"=>["Chemistry", "Cell Biology", "Biotechnology", "Genetics", "Physiology", "Medicine"], "users"=>["Andrew C Ahn", "Muneesh Tewari", "Chi-Sang Poon", "Russell S Phillips"], "doi"=>"https://dx.doi.org/10.1371/journal.pmed.0030208.g001", "stats"=>{"downloads"=>1, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_E_coli_Chemotaxis_/629204", "title"=>"E. coli Chemotaxis", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-22 08:41:03"}

PMC Usage Stats | Further Information

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Relative Metric

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