Antidepressants and Violence: Problems at the Interface of Medicine and Law
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{"title"=>"Antidepressants and violence: Problems at the interface of medicine and law", "type"=>"generic", "authors"=>[{"first_name"=>"David", "last_name"=>"Healy", "scopus_author_id"=>"26643139900"}, {"first_name"=>"Andrew", "last_name"=>"Herxheimer", "scopus_author_id"=>"7006142083"}, {"first_name"=>"David B.", "last_name"=>"Menkes", "scopus_author_id"=>"16073087600"}], "year"=>2006, "source"=>"PLoS Medicine", "identifiers"=>{"sgr"=>"33749033923", "doi"=>"10.1371/journal.pmed.0030372", "pui"=>"44455256", "pmid"=>"16968128", "scopus"=>"2-s2.0-33749033923", "issn"=>"15491277", "isbn"=>"1549-1277\\r1549-1676"}, "id"=>"4faffade-a1b8-38ea-80ce-69702f797fc1", "abstract"=>"Recent regulatory warnings about adverse behavioural effects of antidepressants in susceptible individuals have raised the profi le of these issues with clinicians, patients, and the public. We review available clinical trial data on paroxetine and sertraline and pharmacovigilance studies of paroxetine and fl uoxetine, and outline a series of medico-legal cases involving antidepressants and violence. Both clinical trial and pharmacovigilance data point to possible links between these drugs and violent behaviours. The legal cases outlined returned a variety of verdicts that may in part have stemmed from different judicial processes. Many jurisdictions appear not to have considered the possibility that a prescription drug may induce violence. The association of antidepressant treatment with aggression and violence reported here calls for more clinical trial and epidemiological data to be made available and for good clinical descriptions of the adverse outcomes of treatment. Legal systems are likely to continue to be faced with cases of violence associated with the use of psychotropic drugs, and it may fall to the courts to demand access to currently unavailable data. The problem is international and calls for an international response.", "link"=>"http://www.mendeley.com/research/antidepressants-violence-problems-interface-medicine-law", "reader_count"=>64, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>4, "Librarian"=>1, "Researcher"=>11, "Student > Doctoral Student"=>7, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>4, "Student > Master"=>6, "Other"=>9, "Student > Bachelor"=>7, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>4, "Librarian"=>1, "Researcher"=>11, "Student > Doctoral Student"=>7, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>4, "Student > Master"=>6, "Other"=>9, "Student > Bachelor"=>7, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Engineering"=>1, "Biochemistry, Genetics and Molecular Biology"=>2, "Nursing and Health Professions"=>1, "Agricultural and Biological Sciences"=>6, "Medicine and Dentistry"=>28, "Arts and Humanities"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>1, "Psychology"=>10, "Chemistry"=>1, "Social Sciences"=>6}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>28}, "Chemistry"=>{"Chemistry"=>1}, "Social Sciences"=>{"Social Sciences"=>6}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>10}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>6}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>5}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>2}}, "reader_count_by_country"=>{"Japan"=>1, "Italy"=>1, "United Kingdom"=>1}, "group_count"=>0}

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Figshare

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PMC Usage Stats | Further Information

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Relative Metric

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