The Costs and Cost-Effectiveness of Mass Treatment for Intestinal Nematode Worm Infections Using Different Treatment Thresholds
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"The costs and cost-effectiveness of mass treatment for intestinal nematode worm infections using different treatment thresholds", "type"=>"journal", "authors"=>[{"first_name"=>"Andrew", "last_name"=>"Hall", "scopus_author_id"=>"55196059600"}, {"first_name"=>"Sue", "last_name"=>"Horton", "scopus_author_id"=>"55753185200"}, {"first_name"=>"Nilanthi", "last_name"=>"de Silva", "scopus_author_id"=>"7006678916"}], "year"=>2009, "source"=>"PLoS Neglected Tropical Diseases", "identifiers"=>{"sgr"=>"65549091410", "doi"=>"10.1371/journal.pntd.0000402", "pui"=>"354584680", "pmid"=>"19333371", "scopus"=>"2-s2.0-65549091410", "issn"=>"1935-2735", "isbn"=>"1935-2735 (Electronic)\\r1935-2727 (Linking)"}, "id"=>"824b9f24-cfa7-37ac-91ff-a05ff8417416", "abstract"=>"Background: Abstract It is estimated that almost a half of all of people living in developing countries today are infected with roundworms, hookworms, or whipworms or combinations of these types of intestinal nematode worms. They can all be treated using safe, effective, and inexpensive single-dose generic drugs costing as little as USD 0.03 per person treated when bought in bulk. The disease caused by intestinal nematodes is strongly related to the number of worms in the gut, and it is typical to find that worms tend to be aggregated or clumped in their distribution so that ,20% of people may harbour .80% of all worms. This clumping of worms is greatest when the prevalence is low. When the prevalence rises above 50%, the mean worm burden increases exponentially, worms are less clumped, and more people are likely to have moderate to heavy infections and may be diseased. Children are most at risk. For these reasons, the World Health Organization (WHO) currently recommends mass treatment of children $1 year old without prior diagnosis when the Methods prevalence is $20% and treatment twice a year when the prevalence is $50%. negative binomial probability distribution, then the drug cost of treating diseased individuals was calculated based on and The risk of moderate to heavy infections with intestinal nematodes was estimated by applying the different threshold numbers of worms. Based on this cost analysis, a new three-tier treatment regime is proposed: if the Findings: combined prevalence is .40%, treat all children once a year; .60% treat twice a year; and .80% treat three times a year. Using average data on drug and delivery costs of USD 0.15 to treat a school-age child and USD 0.25 to treat a pre-school child (with provisos) the cost of treating children aged 2–14 years was calculated for 105 low- and low-middle-income countries and for constituent regions of India and China based on estimates of the combined prevalence of intestinal nematode worms therein. The annual cost of the three-tier threshold was estimated to be USD 224 million compared with Conclusion: USD 276 million when the current WHO recommendations for mass treatment were applied. The three-tier treatment thresholds were less expensive and more effective as they allocated a greater proportion of expenditures to treating infected individuals when compared with the WHO thresholds (73% compared with 61%) and treated a larger proportion of individuals with moderate to heavy worm burdens, arbitrarily defined as more than 10 worms per person (31% compared with 21%).", "link"=>"http://www.mendeley.com/research/costs-costeffectiveness-mass-treatment-intestinal-nematode-worm-infections-using-different-treatment-3", "reader_count"=>27, "reader_count_by_academic_status"=>{"Researcher"=>6, "Student > Ph. D. Student"=>5, "Student > Postgraduate"=>3, "Student > Master"=>6, "Student > Bachelor"=>2, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>1, "Professor"=>3}, "reader_count_by_user_role"=>{"Researcher"=>6, "Student > Ph. D. Student"=>5, "Student > Postgraduate"=>3, "Student > Master"=>6, "Student > Bachelor"=>2, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>1, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Environmental Science"=>1, "Nursing and Health Professions"=>2, "Medicine and Dentistry"=>5, "Agricultural and Biological Sciences"=>8, "Veterinary Science and Veterinary Medicine"=>2, "Physics and Astronomy"=>1, "Psychology"=>1, "Social Sciences"=>2, "Immunology and Microbiology"=>2, "Economics, Econometrics and Finance"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>5}, "Social Sciences"=>{"Social Sciences"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>2}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>8}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Unspecified"=>{"Unspecified"=>2}, "Environmental Science"=>{"Environmental Science"=>1}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>2}}, "group_count"=>1}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/65549091410"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/65549091410?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=65549091410&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=65549091410&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/65549091410", "dc:identifier"=>"SCOPUS_ID:65549091410", "eid"=>"2-s2.0-65549091410", "dc:title"=>"The costs and cost-effectiveness of mass treatment for intestinal nematode worm infections using different treatment thresholds", "dc:creator"=>"Hall A.", "prism:publicationName"=>"PLoS Neglected Tropical Diseases", "prism:volume"=>"3", "prism:issueIdentifier"=>"3", "prism:pageRange"=>nil, "prism:coverDate"=>"2009-05-20", "prism:coverDisplayDate"=>"2009", "prism:doi"=>"10.1371/journal.pntd.0000402", "citedby-count"=>"19", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Westminster", "affiliation-city"=>"London", "affiliation-country"=>"United Kingdom"}], "pubmed-id"=>"19333371", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e402", "source-id"=>"11900154404", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosntds%2Farticle%3Fid%3D10.1371%252Fjournal.pntd.0000402", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments | Further Information

Counter

  • {"month"=>"3", "year"=>"2009", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"4", "year"=>"2009", "pdf_views"=>"54", "xml_views"=>"2", "html_views"=>"174"}
  • {"month"=>"5", "year"=>"2009", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"6", "year"=>"2009", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"68"}
  • {"month"=>"7", "year"=>"2009", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"60"}
  • {"month"=>"8", "year"=>"2009", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"73"}
  • {"month"=>"9", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"22"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"26"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"3", "html_views"=>"37"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"26"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"36"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"2", "html_views"=>"31"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"2", "html_views"=>"33"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"22"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"0", "xml_views"=>"1", "html_views"=>"12"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"80"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"46"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"52"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"40"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"34"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"5", "html_views"=>"23"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"52"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"107"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"80"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"83"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"89"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"94"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"91"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"64", "xml_views"=>"0", "html_views"=>"83"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"69", "xml_views"=>"0", "html_views"=>"62"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"69", "xml_views"=>"4", "html_views"=>"81"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"72", "xml_views"=>"1", "html_views"=>"76"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"51"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"40"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"58"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"55"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"86"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"61"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"35"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"36"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"48"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"84"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"30"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"77"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"46"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"46"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"49"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"41"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"55"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"49"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"61"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"49"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"49"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"23"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"3", "html_views"=>"32"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"22"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"32"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"31"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"44"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"20"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"28"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"2", "html_views"=>"13"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/446505", "https://ndownloader.figshare.com/files/446582"], "description"=>"<div><h3>Background</h3><p>It is estimated that almost a half of all of people living in developing countries today are infected with roundworms, hookworms, or whipworms or combinations of these types of intestinal nematode worms. They can all be treated using safe, effective, and inexpensive single-dose generic drugs costing as little as USD 0.03 per person treated when bought in bulk. The disease caused by intestinal nematodes is strongly related to the number of worms in the gut, and it is typical to find that worms tend to be aggregated or clumped in their distribution so that <20% of people may harbour >80% of all worms. This clumping of worms is greatest when the prevalence is low. When the prevalence rises above 50%, the mean worm burden increases exponentially, worms are less clumped, and more people are likely to have moderate to heavy infections and may be diseased. Children are most at risk. For these reasons, the World Health Organization (WHO) currently recommends mass treatment of children ≥1 year old without prior diagnosis when the prevalence is ≥20% and treatment twice a year when the prevalence is ≥50%.</p><h3>Methods and Findings</h3><p>The risk of moderate to heavy infections with intestinal nematodes was estimated by applying the negative binomial probability distribution, then the drug cost of treating diseased individuals was calculated based on different threshold numbers of worms. Based on this cost analysis, a new three-tier treatment regime is proposed: if the combined prevalence is >40%, treat all children once a year; >60% treat twice a year; and >80% treat three times a year. Using average data on drug and delivery costs of USD 0.15 to treat a school-age child and USD 0.25 to treat a pre-school child (with provisos) the cost of treating children aged 2–14 years was calculated for 105 low- and low-middle-income countries and for constituent regions of India and China based on estimates of the combined prevalence of intestinal nematode worms therein. The annual cost of the three-tier threshold was estimated to be USD 224 million compared with USD 276 million when the current WHO recommendations for mass treatment were applied.</p><h3>Conclusion</h3><p>The three-tier treatment thresholds were less expensive and more effective as they allocated a greater proportion of expenditures to treating infected individuals when compared with the WHO thresholds (73% compared with 61%) and treated a larger proportion of individuals with moderate to heavy worm burdens, arbitrarily defined as more than 10 worms per person (31% compared with 21%).</p></div>", "links"=>[], "tags"=>["costs", "cost-effectiveness", "intestinal", "nematode", "worm", "infections", "thresholds"], "article_id"=>148020, "categories"=>["Biological Sciences"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.s001", "https://dx.doi.org/10.1371/journal.pntd.0000402.s002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Costs_and_Cost_Effectiveness_of_Mass_Treatment_for_Intestinal_Nematode_Worm_Infections_Using_Different_Treatment_Thresholds/148020", "title"=>"The Costs and Cost-Effectiveness of Mass Treatment for Intestinal Nematode Worm Infections Using Different Treatment Thresholds", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2009-03-31 02:13:40"}
  • {"files"=>["https://ndownloader.figshare.com/files/902963"], "description"=>"<p>The relationship between the prevalence of infection with an intestinal nematode worm, in this case <i>Ascaris lumbricoides</i>, and the mean worm burden estimated by applying the negative binomial distribution using a clumping parameter (k) that varies linearly with the mean worm burden (see ref. <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402-Guyatt1\" target=\"_blank\">[6]</a>).</p>", "links"=>[], "tags"=>["prevalence", "intestinal", "nematode", "worm", "applying", "binomial", "clumping", "parameter", "varies", "linearly"], "article_id"=>573411, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_relationship_between_the_prevalence_of_infection_with_an_intestinal_nematode_worm_in_this_case_Ascaris_lumbricoides_and_the_mean_worm_burden_estimated_by_applying_the_negative_binomial_distribution_using_a_clumping_parameter_k_that_varies_linearly_wi/573411", "title"=>"The relationship between the prevalence of infection with an intestinal nematode worm, in this case <i>Ascaris lumbricoides</i>, and the mean worm burden estimated by applying the negative binomial distribution using a clumping parameter (k) that varies linearly with the mean worm burden (see ref. [6]).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-03-31 00:56:51"}
  • {"files"=>["https://ndownloader.figshare.com/files/903059"], "description"=>"<p>The method of calculation is described in the text.</p>", "links"=>[], "tags"=>["prevalence", "intestinal", "nematode", "worms", "derived", "presented", "ref", "prevalences", "infections", "hookworm"], "article_id"=>573507, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_map_of_the_prevalence_of_infection_with_any_species_of_intestinal_nematode_worms_derived_from_data_presented_in_ref_2_on_the_national_prevalences_of_combined_infections_with_Ascaris_lumbricoides_Trichuris_trichiura_and_the_two_hookworm_species_Ancylost/573507", "title"=>"A map of the prevalence of infection with any species of intestinal nematode worms derived from data presented in ref [2] on the national prevalences of combined infections with <i>Ascaris lumbricoides</i>, <i>Trichuris trichiura</i> and the two hookworm species <i>Ancylostoma duodenale</i> and <i>Necator americanus</i>.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-03-31 00:58:27"}
  • {"files"=>["https://ndownloader.figshare.com/files/903175"], "description"=>"<p>The method used to calculate the parameters is described in the text. Some values for the proportion infected were <0.0001. Adapted from ref <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402-Hall5\" target=\"_blank\">[48]</a>.</p>a<p><i>k</i> = a+bM in which a = 0.334 and b = 0.0172 <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402-Guyatt2\" target=\"_blank\">[7]</a>.</p>", "links"=>[], "tags"=>["costs", "treating", "infections", "costing", "usd", "calculated", "infected", "diseased", "treated", "defined", "thresholds", "worm"], "article_id"=>573617, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Estimates_of_the_costs_of_treating_infections_with_Ascaris_lumbricoides_using_a_drug_costing_USD_0_03_per_dose_calculated_in_three_ways_per_person_treated_per_infected_person_treated_and_per_diseased_person_treated_defined_using_four_different_thresholds/573617", "title"=>"Estimates of the costs of treating infections with <i>Ascaris lumbricoides</i> using a drug costing USD 0.03 per dose calculated in three ways: per person treated, per infected person treated, and per diseased person treated defined using four different thresholds of worm burden.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-03-31 01:00:17"}
  • {"files"=>["https://ndownloader.figshare.com/files/903219"], "description"=>"<p>Note. All programs combined the distribution of drugs to treat intestinal nematodes with another intervention, either praziquantel for schoolchildren or vitamin A for preschoolers. The costs in stand-alone programmes would be higher, as distribution costs would not be shared with another programme. Although costs are only available for countries in Africa, these are considered to be a reasonable guide to costs in South, Southeast and East Asia. Costs in Latin America and the Caribbean are likely to be higher due to higher salary costs.</p>", "links"=>[], "tags"=>["delivering", "treatments", "albendazole", "praziquantel", "pre-school", "children", "infections", "intestinal", "nematode", "worms", "spp"], "article_id"=>573667, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.t002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Estimates_of_the_cost_of_delivering_single_dose_treatments_with_albendazole_ALB_or_praziquantel_PZQ_to_treat_pre_school_and_school_children_for_infections_with_intestinal_nematode_worms_or_Schistosoma_spp_respectively_/573667", "title"=>"Estimates of the cost of delivering single dose treatments with albendazole (ALB) or praziquantel (PZQ) to treat pre-school and school children for infections with intestinal nematode worms or <i>Schistosoma</i> spp respectively.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-03-31 01:01:07"}
  • {"files"=>["https://ndownloader.figshare.com/files/903274"], "description"=>"<p>Columns 2, 4 and 6 with titles in italics represent differences in approach. Note: 10 developing countries were excluded due to lack of prevalence data (Afghanistan, Belize, Bhutan, Cape Verde, Comoros, Cuba, Djibouti, Lesotho, North Korea and Swaziland). Another 11 smaller countries did not have population age structure data available, and were also omitted: (American Samoa, Antigua, Cook Islands, Dominica,Kiribati, Marshall Islands, Nieu, Palau, Seychelles, St. Kitts, Tuvalu). The former Commonwealth of Independent States countries are also excluded due to lack of revalence data. Source: authors' calculations. Prevalence data are provided in <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402.s001\" target=\"_blank\">Table S1</a> (national data) and <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402.s002\" target=\"_blank\">Table S2</a> (subnational data for India and China).</p>", "links"=>[], "tags"=>["countries", "regions", "india", "china", "prevalence", "x2", "x3", "guidelines", "three-tier"], "article_id"=>573715, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.t003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Classification_of_countries_see_Table_S1_and_regions_of_India_and_China_see_Table_S2_by_prevalence_of_infection_and_annual_treatment_frequency_x0_x1_x2_or_x3_times_based_on_current_WHO_guidelines_19_and_the_new_three_tier_guidelines_proposed_here_/573715", "title"=>"Classification of countries (see Table S1) and regions of India and China (see Table S2) by prevalence of infection and annual treatment frequency (x0, x1, x2 or x3 times) based on current WHO guidelines [19] and the new three-tier guidelines proposed here.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-03-31 01:01:55"}
  • {"files"=>["https://ndownloader.figshare.com/files/903321"], "description"=>"<p>Notes. The population estimates are for children aged 0–14 y from ref. <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402-United1\" target=\"_blank\">[29]</a> converted to age range 2–14 y using the best approximation possible taken from the WHO Life Tables <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402-WHO9\" target=\"_blank\">[32]</a> as follows. The number of person-years lived, <sub>n</sub>L<sub>x</sub> was applied to obtain total person-years lived from zero to below the age of 15 y (<sub>15</sub>L<sub>0</sub>) and from this was subtracted the number of person-years lived below the age of 1, one quarter of the person-years lived between 1 and 5, and one fifth of the person-years lived between 10 and 15, to obtain the proportion of the under-15 population who are at least 2 years old and 14 y or under: i.e. <sub>12</sub>L<sub>2</sub> = <sub>15</sub>L<sub>0</sub>−(<sub>1</sub>L<sub>0</sub>+0.25*<sub>4</sub>L<sub>1</sub>+0.2*<sub>5</sub>L<sub>10</sub>). The underlying data are provided in <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000402#pntd.0000402.s001\" target=\"_blank\">Table S1</a>. Note that the estimates of percentages spent on initially-infected individuals, and those initially infected with 10+ worms, are based on static prevalence, and do not take into account declining prevalence with re-treatment. A dynamic model would be desirable.</p>", "links"=>[], "tags"=>["costs", "treating", "children", "aged", "countries", "grouped", "prevalence", "recommended", "thresholds", "three-tier"], "article_id"=>573768, "categories"=>["Computational Biology"], "users"=>["Andrew Hall", "Sue Horton", "Nilanthi de Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pntd.0000402.t004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Annual_costs_of_treating_children_aged_2_14_y_by_countries_grouped_by_prevalence_see_Table_3_and_depending_on_the_frequency_of_treatment_given_according_to_current_WHO_recommended_thresholds_19_and_the_new_three_tier_thresholds_proposed_here_/573768", "title"=>"Annual costs of treating children aged 2–14 y by countries grouped by prevalence (see Table 3) and depending on the frequency of treatment given according to current WHO recommended thresholds [19] and the new three-tier thresholds proposed here.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-03-31 01:02:48"}

PMC Usage Stats | Further Information

  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "year"=>"2010", "pdf"=>"4", "unique-ip"=>"17", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "unique-ip"=>"16", "pdf"=>"7", "year"=>"2010", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"27", "year"=>"2010", "pdf"=>"9", "unique-ip"=>"24", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"23", "unique-ip"=>"19", "pdf"=>"10", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"13", "year"=>"2010", "pdf"=>"6", "unique-ip"=>"15", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "unique-ip"=>"10", "pdf"=>"6", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "year"=>"2010", "pdf"=>"6", "unique-ip"=>"17", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"17", "unique-ip"=>"15", "pdf"=>"6", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "year"=>"2010", "pdf"=>"7", "unique-ip"=>"20", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"18", "unique-ip"=>"17", "pdf"=>"1", "year"=>"2010", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"9", "year"=>"2010", "pdf"=>"5", "unique-ip"=>"12", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"4", "unique-ip"=>"7", "pdf"=>"3", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"11", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "unique-ip"=>"11", "pdf"=>"4", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "year"=>"2011", "pdf"=>"8", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"13", "unique-ip"=>"13", "pdf"=>"9", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"6", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"11", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"8", "unique-ip"=>"8", "pdf"=>"6", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "year"=>"2011", "pdf"=>"2", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "unique-ip"=>"11", "pdf"=>"5", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"12", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"12", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"3", "unique-ip"=>"5", "pdf"=>"3", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2011", "pdf"=>"1", "unique-ip"=>"8", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"13", "unique-ip"=>"12", "pdf"=>"3", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"14", "year"=>"2012", "pdf"=>"2", "unique-ip"=>"10", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"23", "unique-ip"=>"20", "pdf"=>"2", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"20", "year"=>"2012", "pdf"=>"5", "unique-ip"=>"22", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "unique-ip"=>"6", "pdf"=>"3", "year"=>"2012", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "year"=>"2012", "pdf"=>"1", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"39", "unique-ip"=>"34", "pdf"=>"13", "year"=>"2009", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"37", "year"=>"2009", "pdf"=>"11", "unique-ip"=>"37", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"18", "unique-ip"=>"19", "pdf"=>"8", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"17", "year"=>"2009", "pdf"=>"3", "unique-ip"=>"18", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"13", "unique-ip"=>"18", "pdf"=>"5", "year"=>"2009", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"12", "year"=>"2009", "pdf"=>"9", "unique-ip"=>"16", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"9", "unique-ip"=>"12", "pdf"=>"2", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"23", "year"=>"2009", "pdf"=>"5", "unique-ip"=>"23", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"28", "unique-ip"=>"24", "pdf"=>"10", "year"=>"2009", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "year"=>"2012", "pdf"=>"3", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"11", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"17", "full-text"=>"16", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"11", "full-text"=>"13", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"11", "pdf"=>"7", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"13", "full-text"=>"9", "pdf"=>"5", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"15", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"20", "full-text"=>"18", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"18", "full-text"=>"20", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"13", "full-text"=>"24", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"17", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"15", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"14", "full-text"=>"16", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"21", "full-text"=>"27", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"13", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"15", "full-text"=>"18", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"21", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"22", "full-text"=>"23", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"15", "full-text"=>"22", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"25", "full-text"=>"25", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"50", "full-text"=>"55", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"91", "full-text"=>"108", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"53", "full-text"=>"54", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"313", "full-text"=>"68", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"85", "full-text"=>"44", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"48", "full-text"=>"44", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"69", "full-text"=>"87", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"84", "full-text"=>"87", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"84", "full-text"=>"85", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"71", "full-text"=>"80", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"39", "full-text"=>"40", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"45", "full-text"=>"43", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"79", "full-text"=>"86", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"50", "full-text"=>"53", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"79", "full-text"=>"81", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"69", "full-text"=>"75", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"78", "full-text"=>"91", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"108", "full-text"=>"106", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"81", "full-text"=>"84", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"127", "full-text"=>"139", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"99", "full-text"=>"103", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"90", "full-text"=>"91", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"112", "full-text"=>"117", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}

Relative Metric

{"start_date"=>"2009-01-01T00:00:00Z", "end_date"=>"2009-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Medicine and health sciences", "average_usage"=>[332, 584, 719, 824, 927, 1030, 1139, 1233, 1322, 1402, 1483, 1570, 1649, 1730, 1806, 1873, 1939, 2003, 2068, 2130, 2191, 2248, 2302, 2362, 2427, 2485, 2544, 2599, 2653, 2709, 2778, 2840, 2896, 2950, 3013, 3073, 3137, 3189, 3253, 3305, 3364, 3423, 3489, 3557, 3606, 3668, 3742, 3797, 3852, 3907, 3962, 4027, 4072, 4132, 4193, 4256, 4308, 4366, 4427, 4493, 4556]}, {"subject_area"=>"/Medicine and health sciences/Health care", "average_usage"=>[431, 762, 948, 1112, 1293, 1471, 1604, 1742, 1899, 2018, 2170, 2270, 2387, 2470, 2586, 2727, 2812, 2919, 3041, 3154, 3222, 3295, 3367, 3416, 3496, 3550, 3618, 3690, 3752, 3798, 3870, 3945, 4007, 4073, 4132, 4195, 4251, 4349, 4481, 4564, 4637, 4763, 4869, 5007, 5101, 5190, 5254, 5340, 5415, 5499, 5582, 5634, 5686, 5756, 5845, 5917, 5986, 6093, 6196, 6295, 6397]}, {"subject_area"=>"/Medicine and health sciences/Tropical diseases", "average_usage"=>[262, 539, 658, 749, 834, 916, 1020, 1108, 1196, 1250, 1338, 1408, 1481, 1549, 1611, 1671, 1721, 1786, 1854, 1904, 1968, 2031, 2101, 2158, 2205, 2271, 2326, 2381, 2440, 2488, 2544, 2603, 2658, 2726, 2786, 2839, 2896, 2954, 3019, 3067, 3126, 3181, 3241, 3294, 3367, 3446, 3538, 3634, 3677, 3736, 3785, 3816, 3867, 3946, 4032, 4083, 4121, 4191, 4278, 4344, 4399, 4438]}, {"subject_area"=>"/People and places", "average_usage"=>[340, 621, 760, 868, 956, 1048, 1152, 1251, 1334, 1414, 1499, 1591, 1663, 1753, 1823, 1893, 1955, 2026, 2094, 2178, 2255, 2327, 2390, 2467, 2535, 2613, 2680, 2731, 2780, 2851, 2909, 2986, 3049, 3107, 3177, 3238, 3292, 3360, 3437, 3503, 3564, 3622, 3710, 3812, 3860, 3932, 4002, 4075, 4112, 4156, 4247, 4296, 4386, 4455, 4550, 4613, 4662, 4694, 4869, 4937, 4982]}, {"subject_area"=>"/People and places/Population groupings", "average_usage"=>[326, 591, 716, 814, 900, 987, 1120, 1224, 1289, 1374, 1460, 1550, 1643, 1734, 1802, 1864, 1932, 1993, 2048, 2125, 2213, 2285, 2353, 2413, 2485, 2557, 2605, 2660, 2740, 2788, 2845, 2907, 2959, 3036, 3109, 3163, 3228, 3286, 3351, 3404, 3482, 3562, 3633, 3707, 3749, 3842, 3924, 3985, 4080, 4118, 4176, 4261, 4333, 4379, 4458, 4529, 4578, 4632, 4711, 4767, 4817]}]}
Loading … Spinner
There are currently no alerts