Concerted Efforts to Control or Eliminate Neglected Tropical Diseases: How Much Health Will Be Gained?
Publication Date
February 18, 2016
Journal
PLOS Neglected Tropical Diseases
Authors
Sake J. De Vlas, Wilma A. Stolk, Epke A. Le Rutte, Jan A. C. Hontelez, et al
Volume
10
Issue
2
Pages
e0004386
DOI
https://dx.plos.org/10.1371/journal.pntd.0004386
Publisher URL
http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0004386
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/26890362
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758649
Europe PMC
http://europepmc.org/abstract/MED/26890362
Web of Science
000372567300017
Scopus
84957538279
Mendeley
http://www.mendeley.com/research/concerted-efforts-control-eliminate-neglected-tropical-diseases-much-health-gained
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Mendeley | Further Information

{"title"=>"Concerted Efforts to Control or Eliminate Neglected Tropical Diseases: How Much Health Will Be Gained?", "type"=>"journal", "authors"=>[{"first_name"=>"Sake J.", "last_name"=>"de Vlas", "scopus_author_id"=>"7004465128"}, {"first_name"=>"Wilma A.", "last_name"=>"Stolk", "scopus_author_id"=>"6603001987"}, {"first_name"=>"Epke A.", "last_name"=>"le Rutte", "scopus_author_id"=>"56600872700"}, {"first_name"=>"Jan A.C.", "last_name"=>"Hontelez", "scopus_author_id"=>"35299610800"}, {"first_name"=>"Roel", "last_name"=>"Bakker", "scopus_author_id"=>"7005053766"}, {"first_name"=>"David J.", "last_name"=>"Blok", "scopus_author_id"=>"55671683200"}, {"first_name"=>"Rui", "last_name"=>"Cai", "scopus_author_id"=>"55681108800"}, {"first_name"=>"Tanja A.J.", "last_name"=>"Houweling", "scopus_author_id"=>"10639726000"}, {"first_name"=>"Margarete C.", "last_name"=>"Kulik", "scopus_author_id"=>"55039999800"}, {"first_name"=>"Edeltraud J.", "last_name"=>"Lenk", "scopus_author_id"=>"57144344000"}, {"first_name"=>"Marianne", "last_name"=>"Luyendijk", "scopus_author_id"=>"57144636300"}, {"first_name"=>"Suzette M.", "last_name"=>"Matthijsse", "scopus_author_id"=>"55847836100"}, {"first_name"=>"William K.", "last_name"=>"Redekop", "scopus_author_id"=>"7003856662"}, {"first_name"=>"Inge", "last_name"=>"Wagenaar", "scopus_author_id"=>"55523814000"}, {"first_name"=>"Julie", "last_name"=>"Jacobson", "scopus_author_id"=>"8963456300"}, {"first_name"=>"Nico J.D.", "last_name"=>"Nagelkerke", "scopus_author_id"=>"35743614000"}, {"first_name"=>"Jan H.", "last_name"=>"Richardus", "scopus_author_id"=>"7003977198"}], "year"=>2016, "source"=>"PLoS Neglected Tropical Diseases", "identifiers"=>{"issn"=>"19352735", "doi"=>"10.1371/journal.pntd.0004386", "sgr"=>"84957538279", "scopus"=>"2-s2.0-84957538279", "isbn"=>"1935-2735", "pmid"=>"26890362", "pui"=>"608697978"}, "id"=>"e1b2b49d-13ab-307f-ae48-f16df38b9463", "abstract"=>"BACKGROUND The London Declaration (2012) was formulated to support and focus the control and elimination of ten neglected tropical diseases (NTDs), with targets for 2020 as formulated by the WHO Roadmap. Five NTDs (lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths and trachoma) are to be controlled by preventive chemotherapy (PCT), and four (Chagas' disease, human African trypanosomiasis, leprosy and visceral leishmaniasis) by innovative and intensified disease management (IDM). Guinea worm, virtually eradicated, is not considered here. We aim to estimate the global health impact of meeting these targets in terms of averted morbidity, mortality, and disability adjusted life years (DALYs). METHODS The Global Burden of Disease (GBD) 2010 study provides prevalence and burden estimates for all nine NTDs in 1990 and 2010, by country, age and sex, which were taken as the basis for our calculations. Estimates for other years were obtained by interpolating between 1990 (or the start-year of large-scale control efforts) and 2010, and further extrapolating until 2030, such that the 2020 targets were met. The NTD disease manifestations considered in the GBD study were analyzed as either reversible or irreversible. Health impacts were assessed by comparing the results of achieving the targets with the counterfactual, construed as the health burden had the 1990 (or 2010 if higher) situation continued unabated. PRINCIPLE FINDINGS/CONCLUSIONS Our calculations show that meeting the targets will lead to about 600 million averted DALYs in the period 2011-2030, nearly equally distributed between PCT and IDM-NTDs, with the health gain amongst PCT-NTDs mostly (96%) due to averted disability and amongst IDM-NTDs largely (95%) from averted mortality. These health gains include about 150 million averted irreversible disease manifestations (e.g. blindness) and 5 million averted deaths. Control of soil-transmitted helminths accounts for one third of all averted DALYs. We conclude that the projected health impact of the London Declaration justifies the required efforts.", "link"=>"http://www.mendeley.com/research/concerted-efforts-control-eliminate-neglected-tropical-diseases-much-health-gained", "reader_count"=>77, "reader_count_by_academic_status"=>{"Unspecified"=>6, "Professor > Associate Professor"=>1, "Librarian"=>1, "Researcher"=>14, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Student > Master"=>25, "Other"=>8, "Student > Bachelor"=>3, "Lecturer"=>1, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>6, "Professor > Associate Professor"=>1, "Librarian"=>1, "Researcher"=>14, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Student > Master"=>25, "Other"=>8, "Student > Bachelor"=>3, "Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>9, "Agricultural and Biological Sciences"=>9, "Veterinary Science and Veterinary Medicine"=>4, "Chemistry"=>1, "Decision Sciences"=>1, "Environmental Science"=>3, "Nursing and Health Professions"=>5, "Biochemistry, Genetics and Molecular Biology"=>5, "Mathematics"=>2, "Medicine and Dentistry"=>26, "Neuroscience"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Psychology"=>1, "Social Sciences"=>5, "Immunology and Microbiology"=>2, "Arts and Humanities"=>1, "Business, Management and Accounting"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>26}, "Social Sciences"=>{"Social Sciences"=>5}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Psychology"=>{"Psychology"=>1}, "Mathematics"=>{"Mathematics"=>2}, "Unspecified"=>{"Unspecified"=>9}, "Environmental Science"=>{"Environmental Science"=>3}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Chemistry"=>{"Chemistry"=>1}, "Neuroscience"=>{"Neuroscience"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>2}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>9}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>5}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>5}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>4}}, "reader_count_by_country"=>{"United States"=>1, "United Kingdom"=>1}, "group_count"=>6}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/4234795"], "description"=>"<p>The bold numbers reflect the years lived with disability (YLD) and years of life lost (YLL) for each NTD in 2010, as estimated by the GBD 2010 study [<a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#pntd.0004386.ref001\" target=\"_blank\">1</a>–<a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#pntd.0004386.ref004\" target=\"_blank\">4</a>]. The excess mortality rate (<i>μ</i>*) was chosen to reflect the severity of the sequela. The average disability weights were used to relate YLD to prevalent cases in our calculations for NTDs with multiple sequelae. Salomon et al. [<a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#pntd.0004386.ref024\" target=\"_blank\">24</a>] provide more information about disability weights and lay explanations of sequelae. (a) The original GBD value for LF was 2.74 million YLD, but as Cambodia, Federated States of Micronesia, Maldives, Samoa, Sri Lanka, Togo, Tonga, Vanuatu, and Vietnam had reached elimination before 2010, their remaining burden (total of 0.04 million YLD) was removed from our calculations. (b) The GBD values for leprosy were based on a recalculation; see <a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#sec005\" target=\"_blank\">methods</a> section. (c) A disability weight (DW = 0.097) for visceral leishmaniasis was needed to distinguish it from cutaneous leishmaniasis (DW = 0.013), as both were combined as leishmaniasis in the YLD values available from GBD; YLL due to leishmaniasis was assumed to be fully caused by visceral leishmaniasis.</p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588185, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_31_sequelae_categorized_as_either_reversible_or_irreversible_and_associated_mortality_in_the_Global_Burden_of_Disease_2010_study_for_the_ten_London_Declaration_NTDs_except_Guinea_worm_/2588185", "title"=>"The 31 sequelae (categorized as either reversible or irreversible) and associated mortality in the Global Burden of Disease 2010 study for the ten London Declaration NTDs, except Guinea worm.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-18 16:40:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/4234828"], "description"=>"<p>Estimated number of averted new cases of irreversible disease (in millions) when meeting the WHO Roadmap targets for London Declaration NTDs.</p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588218, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.t003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Estimated_number_of_averted_new_cases_of_irreversible_disease_in_millions_when_meeting_the_WHO_Roadmap_targets_for_London_Declaration_NTDs_/2588218", "title"=>"Estimated number of averted new cases of irreversible disease (in millions) when meeting the WHO Roadmap targets for London Declaration NTDs.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-18 16:40:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/4234813"], "description"=>"<p>All country-specific assumptions for each NTD are provided here: <a href=\"https://erasmusmcmgz.shinyapps.io/dissemination/\" target=\"_blank\">https://erasmusmcmgz.shinyapps.io/dissemination/</a>.</p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588203, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.t002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Interpretations_of_WHO_Roadmap_targets_7_as_used_in_our_calculations_/2588203", "title"=>"Interpretations of WHO Roadmap targets [7] as used in our calculations.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-18 16:40:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/4234783"], "description"=>"<p>Five (lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths and trachoma) are to be controlled by preventive chemotherapy (PCT), and four (Chagas’ disease, human African trypanosomiasis, leprosy and visceral leishmaniasis) by innovative and intensified disease management (IDM). Values are in millions of averted DALYs per 10-year period, subdivided into years of life lost (YLL) and years lived with disability (YLD).</p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588173, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.g002", "stats"=>{"downloads"=>1, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Estimated_overall_health_impact_of_meeting_the_WHO_Roadmap_targets_for_nine_London_Declaration_NTDs_/2588173", "title"=>"Estimated overall health impact of meeting the WHO Roadmap targets for nine London Declaration NTDs.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2016-02-18 16:40:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/4234771"], "description"=>"<p>DALYs are divided into years of life lost (YLL) and years lived with disability (YLD), with the latter subdivided into reversible and irreversible sequelae. Estimates for remaining DALYs were obtained by interpolating between 1990 (or the start-year of large-scale control efforts) and 2010, and further extrapolated until 2030, such that the 2020 targets of the WHO Roadmap were met. Averted DALYs were assessed by comparing the results of achieving the targets with the counterfactual, construed as the health burden had the 1990 (or 2010 if higher) situation continued unabated. The bars for 1990 and 2010 reflect the Global Burden of Disease (GBD) data [<a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#pntd.0004386.ref001\" target=\"_blank\">1</a>–<a href=\"http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0004386#pntd.0004386.ref004\" target=\"_blank\">4</a>], on which all calculations were based. The boxes indicate the most significant (i.e. visible) sequelae; where multiple sequelae make part of the total of reversible or irreversible disease (YLD) for an NTD, their relative contribution (%) to averted YLD in the period 2011–2030 is indicated. Underlying assumptions and more detailed results, both globally and at the country-level can be found here: <a href=\"https://erasmusmcmgz.shinyapps.io/dissemination/\" target=\"_blank\">https://erasmusmcmgz.shinyapps.io/dissemination/</a></p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588158, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.g001", "stats"=>{"downloads"=>1, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Global_trends_of_remaining_and_averted_disability_adjusted_life_years_DALYs_from_1990_to_2030_for_nine_NTDs_that_are_part_of_the_London_Declaration_with_soil_transmitted_helminths_presented_for_ascariasis_hookworm_disease_and_trichuriasis_separately_/2588158", "title"=>"Global trends of remaining and averted disability adjusted life years (DALYs) from 1990 to 2030 for nine NTDs that are part of the London Declaration, with soil-transmitted helminths presented for ascariasis, hookworm disease and trichuriasis separately.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2016-02-18 16:40:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/4234831"], "description"=>"<p>Estimated number of averted deaths (in millions) when meeting the WHO Roadmap targets for the five London Declaration NTDs with associated mortality.</p>", "links"=>[], "tags"=>["NTD disease manifestations", "GBD", "PCT", "IDM", "health impact", "DALY", "Neglected Tropical Diseases"], "article_id"=>2588221, "categories"=>["Biochemistry", "Medicine", "Molecular Biology", "Biotechnology", "Cancer", "Infectious Diseases", "Computational Biology"], "users"=>["Sake J. de Vlas", "Wilma A. Stolk", "Epke A. le Rutte", "Jan A. C. Hontelez", "Roel Bakker", "David J. Blok", "Rui Cai", "Tanja A. J. Houweling", "Margarete C. Kulik", "Edeltraud J. Lenk", "Marianne Luyendijk", "Suzette M. Matthijsse", "William K. Redekop", "Inge Wagenaar", "Julie Jacobson", "Nico J. D. Nagelkerke", "Jan H. Richardus"], "doi"=>"https://dx.doi.org/10.1371/journal.pntd.0004386.t004", "stats"=>{"downloads"=>1, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Estimated_number_of_averted_deaths_in_millions_when_meeting_the_WHO_Roadmap_targets_for_the_five_London_Declaration_NTDs_with_associated_mortality_/2588221", "title"=>"Estimated number of averted deaths (in millions) when meeting the WHO Roadmap targets for the five London Declaration NTDs with associated mortality.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2016-02-18 16:40:50"}

PMC Usage Stats | Further Information

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  • {"unique-ip"=>"21", "full-text"=>"21", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"18", "full-text"=>"18", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"23", "full-text"=>"21", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"27", "full-text"=>"27", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"29", "full-text"=>"29", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"25", "full-text"=>"18", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"22", "full-text"=>"26", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"30", "full-text"=>"51", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
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  • {"unique-ip"=>"21", "full-text"=>"30", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"19", "full-text"=>"19", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"5", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"14", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"16", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"12", "full-text"=>"15", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}

Relative Metric

{"start_date"=>"2016-01-01T00:00:00Z", "end_date"=>"2016-12-31T00:00:00Z", "subject_areas"=>[]}
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