First Identification and Description of Rickettsioses and Q Fever as Causes of Acute Febrile Illness in Nicaragua
Publication Date
December 30, 2016
Authors
Megan E. Reller, Ijeuru Chikeka, Jeremy J. Miles, J. Stephen Dumler, et al
Volume
10
Issue
12
Pages
e0005185
DOI
https://dx.plos.org/10.1371/journal.pntd.0005185
Publisher URL
http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0005185
Scopus
85008698723
Mendeley
http://www.mendeley.com/research/first-identification-description-rickettsioses-q-fever-causes-acute-febrile-illness-nicaragua
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Mendeley | Further Information

{"title"=>"First Identification and Description of Rickettsioses and Q Fever as Causes of Acute Febrile Illness in Nicaragua", "type"=>"journal", "authors"=>[{"first_name"=>"Megan E.", "last_name"=>"Reller", "scopus_author_id"=>"7003447083"}, {"first_name"=>"Ijeuru", "last_name"=>"Chikeka", "scopus_author_id"=>"56655153900"}, {"first_name"=>"Jeremy J.", "last_name"=>"Miles", "scopus_author_id"=>"56310026000"}, {"first_name"=>"J. Stephen", "last_name"=>"Dumler", "scopus_author_id"=>"7005605483"}, {"first_name"=>"Christopher W.", "last_name"=>"Woods", "scopus_author_id"=>"7202272125"}, {"first_name"=>"Orlando", "last_name"=>"Mayorga", "scopus_author_id"=>"55556342700"}, {"first_name"=>"Armando J.", "last_name"=>"Matute", "scopus_author_id"=>"6506891583"}], "year"=>2016, "source"=>"PLoS Neglected Tropical Diseases", "identifiers"=>{"doi"=>"10.1371/journal.pntd.0005185", "pui"=>"613987269", "scopus"=>"2-s2.0-85008698723", "issn"=>"19352735", "pmid"=>"28036394", "sgr"=>"85008698723"}, "id"=>"84bea8a1-48e6-3408-bb43-dcb54d6cb10e", "abstract"=>"BACKGROUND: Rickettsial infections and Q fever present similarly to other acute febrile illnesses, but are infrequently diagnosed because of limited diagnostic tools. Despite sporadic reports, rickettsial infections and Q fever have not been prospectively studied in Central America. METHODOLOGY/PRINCIPAL FINDINGS: We enrolled consecutive patients presenting with undifferentiated fever in western Nicaragua and collected epidemiologic and clinical data and acute and convalescent sera. We used ELISA for screening and paired sera to confirm acute (>/=4-fold rise in titer) spotted fever and typhus group rickettsial infections and Q fever as well as past (stable titer) infections. Characteristics associated with both acute and past infection were assessed. CONCLUSIONS/SIGNIFICANCE: We enrolled 825 patients and identified acute rickettsial infections and acute Q fever in 0.9% and 1.3%, respectively. Clinical features were non-specific and neither rickettsial infections nor Q fever were considered or treated. Further study is warranted to define the burden of these infections in Central America.", "link"=>"http://www.mendeley.com/research/first-identification-description-rickettsioses-q-fever-causes-acute-febrile-illness-nicaragua", "reader_count"=>10, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>1, "Student > Doctoral Student"=>1, "Researcher"=>4, "Student > Master"=>3, "Student > Bachelor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>1, "Student > Doctoral Student"=>1, "Researcher"=>4, "Student > Master"=>3, "Student > Bachelor"=>1}, "reader_count_by_subject_area"=>{"Nursing and Health Professions"=>1, "Medicine and Dentistry"=>3, "Agricultural and Biological Sciences"=>2, "Social Sciences"=>1, "Immunology and Microbiology"=>1, "Unspecified"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Social Sciences"=>{"Social Sciences"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>2}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Unspecified"=>{"Unspecified"=>2}}, "group_count"=>0}

Scopus | Further Information

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