Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide Approach
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Accuracy of predicting the genetic risk of disease using a genome-wide approach", "type"=>"journal", "authors"=>[{"first_name"=>"Hans D.", "last_name"=>"Daetwyler", "scopus_author_id"=>"24586822900"}, {"first_name"=>"Beatriz", "last_name"=>"Villanueva", "scopus_author_id"=>"56054662400"}, {"first_name"=>"John A.", "last_name"=>"Woolliams", "scopus_author_id"=>"7003804673"}], "year"=>2008, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"352553452", "sgr"=>"54449097329", "pmid"=>"18852893", "scopus"=>"2-s2.0-54449097329", "isbn"=>"1932-6203 (Electronic)", "doi"=>"10.1371/journal.pone.0003395", "issn"=>"19326203"}, "id"=>"5cfed5d7-b374-345f-8fa7-65d42f8356bb", "abstract"=>"BACKGROUND: The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for which a large number of loci contribute to the genetic variance. The large numbers of single nucleotide polymorphisms now available provide new opportunities for predicting genetic risk of complex diseases with high accuracy. METHODOLOGY/PRINCIPAL FINDINGS: We have derived simple deterministic formulae to predict the accuracy of predicted genetic risk from population or case control studies using a genome-wide approach and assuming a dichotomous disease phenotype with an underlying continuous liability. We show that the prediction equations are special cases of the more general problem of predicting the accuracy of estimates of genetic values of a continuous phenotype. Our predictive equations are responsive to all parameters that affect accuracy and they are independent of allele frequency and effect distributions. Deterministic prediction errors when tested by simulation were generally small. The common link among the expressions for accuracy is that they are best summarized as the product of the ratio of number of phenotypic records per number of risk loci and the observed heritability. CONCLUSIONS/SIGNIFICANCE: This study advances the understanding of the relative power of case control and population studies of disease. The predictions represent an upper bound of accuracy which may be achievable with improved effect estimation methods. The formulae derived will help researchers determine an appropriate sample size to attain a certain accuracy when predicting genetic risk.", "link"=>"http://www.mendeley.com/research/accuracy-predicting-genetic-risk-disease-using-genomewide-approach-1", "reader_count"=>228, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>13, "Researcher"=>65, "Student > Doctoral Student"=>15, "Student > Ph. D. Student"=>71, "Student > Postgraduate"=>5, "Student > Master"=>28, "Other"=>4, "Student > Bachelor"=>8, "Lecturer"=>4, "Lecturer > Senior Lecturer"=>1, "Professor"=>12}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>13, "Researcher"=>65, "Student > Doctoral Student"=>15, "Student > Ph. D. Student"=>71, "Student > Postgraduate"=>5, "Student > Master"=>28, "Other"=>4, "Student > Bachelor"=>8, "Lecturer"=>4, "Lecturer > Senior Lecturer"=>1, "Professor"=>12}, "reader_count_by_subject_area"=>{"Unspecified"=>9, "Agricultural and Biological Sciences"=>162, "Veterinary Science and Veterinary Medicine"=>3, "Business, Management and Accounting"=>1, "Computer Science"=>6, "Earth and Planetary Sciences"=>1, "Economics, Econometrics and Finance"=>9, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>10, "Mathematics"=>8, "Medicine and Dentistry"=>12, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>1, "Psychology"=>2, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>12}, "Social Sciences"=>{"Social Sciences"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Psychology"=>{"Psychology"=>2}, "Mathematics"=>{"Mathematics"=>8}, "Unspecified"=>{"Unspecified"=>9}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>9}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>162}, "Computer Science"=>{"Computer Science"=>6}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>10}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>3}}, "reader_count_by_country"=>{"Colombia"=>2, "United States"=>5, "United Kingdom"=>1, "Switzerland"=>1, "Sweden"=>1, "Netherlands"=>2, "Finland"=>1, "Brazil"=>2, "Poland"=>1, "Denmark"=>1, "Mexico"=>1, "France"=>1, "Australia"=>1, "Germany"=>3}, "group_count"=>12}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/54449097329"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/54449097329?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=54449097329&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=54449097329&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/54449097329", "dc:identifier"=>"SCOPUS_ID:54449097329", "eid"=>"2-s2.0-54449097329", "dc:title"=>"Accuracy of predicting the genetic risk of disease using a genome-wide approach", "dc:creator"=>"Daetwyler H.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"3", "prism:issueIdentifier"=>"10", "prism:pageRange"=>nil, "prism:coverDate"=>"2008-10-14", "prism:coverDisplayDate"=>"14 October 2008", "prism:doi"=>"10.1371/journal.pone.0003395", "citedby-count"=>"311", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Edinburgh, Roslin Institute", "affiliation-city"=>"Midlothian", "affiliation-country"=>"United Kingdom"}, {"@_fa"=>"true", "affilname"=>"Wageningen University and Research Centre", "affiliation-city"=>"Wageningen", "affiliation-country"=>"Netherlands"}], "pubmed-id"=>"18852893", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e3395", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0003395", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"10", "year"=>"2008", "pdf_views"=>"134", "xml_views"=>"2", "html_views"=>"421"}
  • {"month"=>"11", "year"=>"2008", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"91"}
  • {"month"=>"12", "year"=>"2008", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"64"}
  • {"month"=>"1", "year"=>"2009", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"2", "year"=>"2009", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"3", "year"=>"2009", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"42"}
  • {"month"=>"4", "year"=>"2009", "pdf_views"=>"9", "xml_views"=>"3", "html_views"=>"25"}
  • {"month"=>"5", "year"=>"2009", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"6", "year"=>"2009", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"34"}
  • {"month"=>"7", "year"=>"2009", "pdf_views"=>"18", "xml_views"=>"1", "html_views"=>"44"}
  • {"month"=>"8", "year"=>"2009", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"9", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"20"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"29"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"47"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"3", "html_views"=>"36"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"13", "xml_views"=>"2", "html_views"=>"43"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"28", "xml_views"=>"2", "html_views"=>"51"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"12", "xml_views"=>"2", "html_views"=>"34"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"34"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"42"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"52"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"95"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"69"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"32", "xml_views"=>"2", "html_views"=>"67"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"48"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"50"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"66"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"33", "xml_views"=>"1", "html_views"=>"72"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"20", "xml_views"=>"5", "html_views"=>"52"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"63"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"62"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"97"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"86"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"104"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"75", "xml_views"=>"0", "html_views"=>"89"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"81", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"80", "xml_views"=>"0", "html_views"=>"124"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"80", "xml_views"=>"1", "html_views"=>"116"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"30", "xml_views"=>"1", "html_views"=>"126"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"101"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"73"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"72"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"19", "xml_views"=>"2", "html_views"=>"68"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"27", "xml_views"=>"2", "html_views"=>"83"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"85"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"80"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"67"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"2", "html_views"=>"46"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"82"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"24", "xml_views"=>"2", "html_views"=>"86"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"42"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"71"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"85"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"94"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"63"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"57"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"125"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"94"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"134"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"117"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"133"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"108"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"92"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"83"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"67"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"92"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"77"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"72"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"10", "xml_views"=>"3", "html_views"=>"68"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"97"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"36", "xml_views"=>"3", "html_views"=>"104"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"98"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"93", "xml_views"=>"1", "html_views"=>"118"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"82"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"31", "xml_views"=>"3", "html_views"=>"69"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"59"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"22", "xml_views"=>"2", "html_views"=>"128"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"130"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"22", "xml_views"=>"3", "html_views"=>"75"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"3", "html_views"=>"74"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"31", "xml_views"=>"2", "html_views"=>"55"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"48"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"56"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"31", "xml_views"=>"2", "html_views"=>"60"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"4", "html_views"=>"47"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"34"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"56"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"47"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"52"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"39", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"59"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"32"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/918756"], "description"=>"a<p> = heritability on liability scale.</p>b<p><i>λ</i> = number of phenotypes per number of loci.</p>c<p>D<sub>P</sub> = population study of dichotomous phenotypes.</p>d<p>D<sub>C</sub> = case control study of dichotomous phenotypes.</p>e<p>P = predicted accuracy of additive genetic values.</p>f<p>% error = percentage prediction error = 100(P−accuracy from simulation)/P.</p>", "links"=>[], "tags"=>["dichotomous", "prevalence", "varies", "se"], "article_id"=>589214, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.t004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Accuracy_for_a_dichotomous_disease_trait_as_prevalence_varies_a_b_955__1_SE_range_0_0026_0_0048_/589214", "title"=>"Accuracy for a dichotomous disease trait as prevalence varies (<sup>a</sup>, <sup>b</sup><i>λ</i> = 1, SE range 0.0026–0.0048).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-10-14 02:33:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/454132", "https://ndownloader.figshare.com/files/454205"], "description"=>"<div><h3>Background</h3><p>The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for which a large number of loci contribute to the genetic variance. The large numbers of single nucleotide polymorphisms now available provide new opportunities for predicting genetic risk of complex diseases with high accuracy.</p><h3>Methodology/Principal Findings</h3><p>We have derived simple deterministic formulae to predict the accuracy of predicted genetic risk from population or case control studies using a genome-wide approach and assuming a dichotomous disease phenotype with an underlying continuous liability. We show that the prediction equations are special cases of the more general problem of predicting the accuracy of estimates of genetic values of a continuous phenotype. Our predictive equations are responsive to all parameters that affect accuracy and they are independent of allele frequency and effect distributions. Deterministic prediction errors when tested by simulation were generally small. The common link among the expressions for accuracy is that they are best summarized as the product of the ratio of number of phenotypic records per number of risk loci and the observed heritability.</p><h3>Conclusions/Significance</h3><p>This study advances the understanding of the relative power of case control and population studies of disease. The predictions represent an upper bound of accuracy which may be achievable with improved effect estimation methods. The formulae derived will help researchers determine an appropriate sample size to attain a certain accuracy when predicting genetic risk.</p></div>", "links"=>[], "tags"=>["predicting", "genome-wide"], "article_id"=>149475, "categories"=>["Genetics", "Mathematics", "Cancer"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0003395.s001", "https://dx.doi.org/10.1371/journal.pone.0003395.s002"], "stats"=>{"downloads"=>5, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Accuracy_of_Predicting_the_Genetic_Risk_of_Disease_Using_a_Genome_Wide_Approach/149475", "title"=>"Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide Approach", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2008-10-14 02:37:55"}
  • {"files"=>["https://ndownloader.figshare.com/files/918869"], "description"=>"a<p><i>n<sub>G</sub></i> = number of loci.</p>b<p><i>n<sub>P</sub></i> = number of phenotypes.</p>c<p> = observed heritability.</p>", "links"=>[], "tags"=>["phenotype", "loci", "zero", "se"], "article_id"=>589329, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.t003", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Accuracy_for_continuous_phenotype_when_setting_0_95_of_n_G_a_loci_to_zero_955__0_02_400_n_P_b_20_000_n_G_SE_range_0_0042_0_0057_/589329", "title"=>"Accuracy for continuous phenotype when setting 0.95 of <i>n<sub>G</sub></i><sup>a</sup> loci to zero (<i>λ</i> = 0.02 = 400<i>n<sub>P</sub></i><sup>b</sup>/20,000<i>n<sub>G</sub></i>, SE range 0.0042–0.0057).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-10-14 02:35:29"}
  • {"files"=>["https://ndownloader.figshare.com/files/918667"], "description"=>"<p>Contour plot of predicted accuracy for varied prevalence and additive heritability on the observed scale, in population studies (dashed vertical line) and case control studies (solid line) of dichotomous phenotypes. Each contour represents a line of constant accuracy, starting from the right 0.9, 0.8, 0.7, and 0.6. The narrowly dashed line is derived from Equation (5) with , so values below this line are not possible under the liability model.</p>", "links"=>[], "tags"=>["designs", "dichotomous"], "article_id"=>589131, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.g002", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Predicted_accuracy_of_estimated_genetic_risk_from_population_and_case_control_designs_of_a_dichotomous_phenotype_/589131", "title"=>"Predicted accuracy of estimated genetic risk from population and case control designs of a dichotomous phenotype.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2008-10-14 02:32:11"}
  • {"files"=>["https://ndownloader.figshare.com/files/918846"], "description"=>"a<p><i>λ</i> = number of phenotypes per number of loci.</p>b<p>Beta = beta distribution (alpha = 0.3, theta = 0.3) of allele frequencies.</p>c<p>Nrm = normal distribution of allele effects.</p>d<p>Exp = exponential distribution of allele effects.</p>f<p>Uni = uniform distribution of allele frequencies.</p>", "links"=>[], "tags"=>["distributions", "allele", "phenotype", "observed"], "article_id"=>589303, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.t002", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_effects_of_different_distributions_of_allele_frequency_and_effects_on_accuracy_in_a_continuous_phenotype_with_observed_heritability_8202_8202_0_5_SE_range_0_0004_8211_0_0057_/589303", "title"=>"The effects of different distributions of allele frequency and effects on accuracy in a continuous phenotype with observed heritability = 0.5 (SE range 0.0004–0.0057).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-10-14 02:35:03"}
  • {"files"=>["https://ndownloader.figshare.com/files/918808"], "description"=>"a<p><i>λ</i> = number of phenotypes per number of loci.</p>b<p><i>h</i><sup>2</sup> = heritability (observed scale for C and D<sub>P</sub>, liability scale for D<sub>C</sub>).</p>c<p>P = predicted accuracy of estimated additive genetic value.</p>d<p>% error = percentage prediction error = 100(P−accuracy from simulation)/P.</p>e<p>C = continuous phenotype.</p>f<p>D<sub>P</sub> = dichotomous phenotype, population study.</p>g<p>D<sub>C</sub> = dichotomous phenotype, case control study.</p>", "links"=>[], "tags"=>["assessed", "simulation"], "article_id"=>589272, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.t001", "stats"=>{"downloads"=>5, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Predicted_accuracy_and_percentage_prediction_error_assessed_by_simulation_with_disease_prevalence_8202_8202_0_1_SE_range_0_0004_8211_0_0065_/589272", "title"=>"Predicted accuracy and percentage prediction error assessed by simulation with disease prevalence = 0.1 (SE range 0.0004–0.0065).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-10-14 02:34:32"}
  • {"files"=>["https://ndownloader.figshare.com/files/918787"], "description"=>"a<p> = heritability on liability scale.</p>b<p> = heritability on observed scale.</p>c<p><i>λ</i> = number of phenotypes per number of loci.</p>", "links"=>[], "tags"=>["dichotomous", "phenotype", "prevalence", "varies", "stays", "se"], "article_id"=>589238, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.t005", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Simulated_accuracy_of_a_population_study_for_a_dichotomous_phenotype_as_prevalence_and_a_varies_and_b_stays_constant_955_c__10_predicted_accuracy_0_816_Equation_4_SE_range_0_0025_0_0038_/589238", "title"=>"Simulated accuracy of a population study for a dichotomous phenotype as prevalence and <sup>a</sup> varies and <sup>b</sup> stays constant (<i>λ</i><sup>c</sup> = 10, , predicted accuracy = 0.816, Equation (4), SE range 0.0025–0.0038).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2008-10-14 02:33:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/918572"], "description"=>"<p>Predicted accuracy of estimated additive genetic values of a continuous phenotype as a function of observed heritability and number of phenotypes per genotype tested, <i>λ</i> = 0.02, 0.1, 0.5, 1, 2, 5, 10 and 20 from minimum to maximum accuracy respectively.</p>", "links"=>[], "tags"=>["genetics and genomics", "computational biology/genomics", "genetics and genomics/animal genetics", "genetics and genomics/complex traits", "genetics and genomics/genetics of disease", "genetics and genomics/medical genetics", "genetics and genomics/population genetics", "mathematics/statistics"], "article_id"=>589025, "categories"=>["Genetics", "Mathematics", "Infectious Diseases"], "users"=>["Hans D. Daetwyler", "Beatriz Villanueva", "John A. Woolliams"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0003395.g001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Predicted_accuracy_of_estimated_genetic_values_of_a_continuous_phenotype_/589025", "title"=>"Predicted accuracy of estimated genetic values of a continuous phenotype.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2008-10-14 02:30:25"}

PMC Usage Stats | Further Information

  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"16", "year"=>"2010", "pdf"=>"8", "unique-ip"=>"13", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"32", "unique-ip"=>"27", "pdf"=>"12", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"10", "year"=>"2010", "pdf"=>"6", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"15", "unique-ip"=>"16", "pdf"=>"9", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"15", "year"=>"2010", "pdf"=>"7", "unique-ip"=>"14", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "unique-ip"=>"16", "pdf"=>"12", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2010", "pdf"=>"8", "unique-ip"=>"7", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"14", "unique-ip"=>"8", "pdf"=>"6", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"5", "year"=>"2010", "pdf"=>"6", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"5", "unique-ip"=>"8", "pdf"=>"4", "year"=>"2010", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2010", "pdf"=>"4", "unique-ip"=>"7", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"5", "pdf"=>"4", "year"=>"2010", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"11", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"4", "unique-ip"=>"5", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"8", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"9", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"5", "unique-ip"=>"6", "pdf"=>"6", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"13", "year"=>"2011", "pdf"=>"9", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"7", "unique-ip"=>"14", "pdf"=>"9", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2011", "pdf"=>"5", "unique-ip"=>"7", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "unique-ip"=>"3", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"2", "year"=>"2011", "pdf"=>"0", "unique-ip"=>"2", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"4", "pdf"=>"2", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2011", "pdf"=>"3", "unique-ip"=>"6", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"1", "unique-ip"=>"2", "pdf"=>"1", "year"=>"2011", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"1", "unique-ip"=>"4", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "unique-ip"=>"7", "pdf"=>"4", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2012", "pdf"=>"3", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"3", "unique-ip"=>"3", "pdf"=>"1", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"7", "year"=>"2012", "pdf"=>"4", "unique-ip"=>"8", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"32", "unique-ip"=>"31", "pdf"=>"23", "year"=>"2008", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"39", "year"=>"2008", "pdf"=>"19", "unique-ip"=>"31", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"20", "unique-ip"=>"19", "pdf"=>"15", "year"=>"2008", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"21", "year"=>"2009", "pdf"=>"13", "unique-ip"=>"26", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "unique-ip"=>"18", "pdf"=>"14", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"15", "year"=>"2009", "pdf"=>"11", "unique-ip"=>"17", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"18", "unique-ip"=>"20", "pdf"=>"14", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"17", "year"=>"2009", "pdf"=>"8", "unique-ip"=>"15", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "unique-ip"=>"4", "pdf"=>"3", "year"=>"2009", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"6", "year"=>"2009", "pdf"=>"9", "unique-ip"=>"11", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"13", "unique-ip"=>"12", "pdf"=>"7", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"16", "year"=>"2009", "pdf"=>"15", "unique-ip"=>"16", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"8", "unique-ip"=>"9", "pdf"=>"3", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"19", "year"=>"2009", "pdf"=>"13", "unique-ip"=>"21", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"36", "unique-ip"=>"32", "pdf"=>"19", "year"=>"2009", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"4", "year"=>"2012", "pdf"=>"5", "unique-ip"=>"5", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"6", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"2", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"4", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"2", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"16", "full-text"=>"15", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"7", "full-text"=>"10", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"12", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"17", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"10", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"7", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"17", "full-text"=>"13", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"3", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"16", "full-text"=>"15", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"10", "full-text"=>"12", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"7", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"25", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"12", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"11", "full-text"=>"14", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"25", "full-text"=>"24", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"9", "full-text"=>"8", "pdf"=>"13", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"23", "full-text"=>"14", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"19", "full-text"=>"19", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}

Relative Metric

{"start_date"=>"2008-01-01T00:00:00Z", "end_date"=>"2008-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[324, 674, 863, 1015, 1146, 1259, 1360, 1452, 1540, 1621, 1704, 1776, 1843, 1905, 1968, 2029, 2097, 2162, 2233, 2289, 2352, 2412, 2476, 2538, 2601, 2655, 2714, 2777, 2841, 2894, 2946, 2998, 3047, 3103, 3151, 3201, 3258, 3317, 3369, 3424, 3471, 3521, 3583, 3625, 3687, 3743, 3788, 3838, 3896, 3953, 4015, 4075, 4148, 4201, 4275, 4347, 4420, 4486, 4535, 4592, 4660, 4731, 4792, 4845, 4901, 4971, 5027, 5089, 5148, 5200, 5261, 5318, 5374]}, {"subject_area"=>"/Biology and life sciences/Evolutionary biology", "average_usage"=>[372, 729, 958, 1108, 1266, 1374, 1469, 1569, 1626, 1700, 1806, 1875, 1944, 2012, 2088, 2147, 2206, 2271, 2324, 2393, 2445, 2506, 2574, 2642, 2703, 2777, 2830, 2895, 2951, 2994, 3034, 3071, 3135, 3191, 3255, 3317, 3374, 3422, 3484, 3529, 3584, 3612, 3661, 3710, 3766, 3830, 3876, 3940, 3985, 4048, 4089, 4134, 4182, 4227, 4313, 4369, 4486, 4542, 4603, 4695, 4753, 4811, 4862, 4968, 5017, 5096, 5151, 5214, 5256, 5338, 5421, 5486, 5523]}, {"subject_area"=>"/Biology and life sciences/Genetics", "average_usage"=>[329, 686, 873, 1009, 1130, 1239, 1337, 1426, 1509, 1585, 1667, 1746, 1816, 1880, 1937, 1999, 2058, 2120, 2179, 2245, 2311, 2374, 2437, 2511, 2565, 2616, 2671, 2723, 2783, 2844, 2902, 2958, 3017, 3056, 3104, 3169, 3206, 3249, 3298, 3354, 3428, 3479, 3526, 3579, 3628, 3679, 3727, 3771, 3819, 3865, 3927, 4006, 4075, 4116, 4164, 4250, 4323, 4380, 4436, 4492, 4547, 4599, 4652, 4708, 4761, 4811, 4889, 4966, 5025, 5071, 5134, 5186, 5258]}, {"subject_area"=>"/Biology and life sciences/Population biology", "average_usage"=>[349, 704, 911, 1075, 1165, 1272, 1340, 1452, 1534, 1604, 1672, 1722, 1787, 1845, 1902, 1974, 2047, 2114, 2188, 2269, 2330, 2396, 2463, 2546, 2617, 2666, 2725, 2778, 2853, 2903, 2942, 2974, 3017, 3052, 3090, 3129, 3201, 3249, 3290, 3339, 3379, 3433, 3507, 3565, 3602, 3651, 3732, 3788, 3850, 3906, 3940, 4005, 4055, 4103, 4157, 4241, 4356, 4395, 4486, 4530, 4596, 4669, 4708, 4772, 4820, 4869, 4902, 4943, 4989, 5037, 5086, 5145, 5176]}]}
Loading … Spinner
There are currently no alerts