mRuby, a Bright Monomeric Red Fluorescent Protein for Labeling of Subcellular Structures
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"mRuby, a bright monomeric red fluorescent protein for labeling of subcellular structures", "type"=>"journal", "authors"=>[{"first_name"=>"Simone", "last_name"=>"Kredel", "scopus_author_id"=>"23004563200"}, {"first_name"=>"Franz", "last_name"=>"Oswald", "scopus_author_id"=>"7005448748"}, {"first_name"=>"Karin", "last_name"=>"Nienhaus", "scopus_author_id"=>"6701801724"}, {"first_name"=>"Karen", "last_name"=>"Deuschle", "scopus_author_id"=>"7003412246"}, {"first_name"=>"Carlheinz", "last_name"=>"Röcker", "scopus_author_id"=>"6602229183"}, {"first_name"=>"Michael", "last_name"=>"Wolff", "scopus_author_id"=>"22636085200"}, {"first_name"=>"Ralf", "last_name"=>"Heilker", "scopus_author_id"=>"6602638646"}, {"first_name"=>"G. Ulrich", "last_name"=>"Nienhaus", "scopus_author_id"=>"7007133242"}, {"first_name"=>"Jörg", "last_name"=>"Wiedenmann", "scopus_author_id"=>"6603258810"}], "year"=>2009, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"84887212538", "doi"=>"10.1371/journal.pone.0004391", "pui"=>"354233123", "pmid"=>"19194514", "scopus"=>"2-s2.0-84887212538", "issn"=>"19326203", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)"}, "id"=>"5ef2ab42-d082-3237-8022-d0f0a1c48341", "abstract"=>"A monomeric variant of the red fluorescent protein eqFP611, mRuby, is described. With excitation and emission maxima at 558 nm and 605 nm, respectively, and a large Stokes shift of 47 nm, mRuby appears particularly useful for imaging applications. The protein shows an exceptional resistance to denaturation at pH extremes. Moreover, mRuby is about ten-fold brighter compared to EGFP when being targeted to the endoplasmic reticulum. The engineering process of eqFP611 revealed that the C-terminal tail of the protein acts as a natural peroxisomal targeting signal (PTS). Using an mRuby variant carrying the eqFP611-PTS, we discovered that ordered inheritance of peroxisomes is widespread during mitosis of different mammalian cell types. The ordered partitioning is realized by the formation of peroxisome clusters around the poles of the mitotic spindle and ensures that equal numbers of the organelle are inherited by the daughter cells. The unique spectral properties make mRuby the marker of choice for a multitude of cell biological applications. Moreover, the use of mRuby has allowed novel insights in the biology of organelles responsible for severe human diseases.", "link"=>"http://www.mendeley.com/research/mruby-bright-monomeric-red-fluorescent-protein-labeling-subcellular-structures", "reader_count"=>308, "reader_count_by_academic_status"=>{"Unspecified"=>6, "Professor > Associate Professor"=>13, "Student > Doctoral Student"=>21, "Researcher"=>75, "Student > Ph. D. Student"=>92, "Student > Postgraduate"=>7, "Student > Master"=>38, "Other"=>9, "Student > Bachelor"=>34, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>10}, "reader_count_by_user_role"=>{"Unspecified"=>6, "Professor > Associate Professor"=>13, "Student > Doctoral Student"=>21, "Researcher"=>75, "Student > Ph. D. Student"=>92, "Student > Postgraduate"=>7, "Student > Master"=>38, "Other"=>9, "Student > Bachelor"=>34, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>10}, "reader_count_by_subject_area"=>{"Unspecified"=>8, "Agricultural and Biological Sciences"=>189, "Chemical Engineering"=>2, "Chemistry"=>18, "Computer Science"=>1, "Earth and Planetary Sciences"=>2, "Engineering"=>10, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>36, "Materials Science"=>1, "Medicine and Dentistry"=>6, "Neuroscience"=>15, "Sports and Recreations"=>1, "Physics and Astronomy"=>13, "Social Sciences"=>1, "Immunology and Microbiology"=>4}, "reader_count_by_subdiscipline"=>{"Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>6}, "Social Sciences"=>{"Social Sciences"=>1}, "Sports and Recreations"=>{"Sports and Recreations"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>13}, "Unspecified"=>{"Unspecified"=>8}, "Environmental Science"=>{"Environmental Science"=>1}, "Chemical Engineering"=>{"Chemical Engineering"=>2}, "Engineering"=>{"Engineering"=>10}, "Chemistry"=>{"Chemistry"=>18}, "Neuroscience"=>{"Neuroscience"=>15}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>2}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>4}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>189}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>36}}, "reader_count_by_country"=>{"United States"=>6, "Japan"=>3, "United Kingdom"=>2, "Portugal"=>1, "Switzerland"=>4, "Russia"=>1, "Spain"=>1, "Netherlands"=>2, "Czech Republic"=>1, "Belgium"=>3, "China"=>1, "France"=>1, "Germany"=>3}, "group_count"=>5}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212538"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212538?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84887212538&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84887212538&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84887212538", "dc:identifier"=>"SCOPUS_ID:84887212538", "eid"=>"2-s2.0-84887212538", "dc:title"=>"mRuby, a bright monomeric red fluorescent protein for labeling of subcellular structures", "dc:creator"=>"Kredel S.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"4", "prism:issueIdentifier"=>"2", "prism:pageRange"=>nil, "prism:coverDate"=>"2009-02-05", "prism:coverDisplayDate"=>"5 February 2009", "prism:doi"=>"10.1371/journal.pone.0004391", "citedby-count"=>"137", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Universität Ulm", "affiliation-city"=>"Ulm", "affiliation-country"=>"Germany"}], "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e4391", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0004391", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"2", "year"=>"2009", "pdf_views"=>"157", "xml_views"=>"0", "html_views"=>"506"}
  • {"month"=>"3", "year"=>"2009", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"134"}
  • {"month"=>"4", "year"=>"2009", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"81"}
  • {"month"=>"5", "year"=>"2009", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"62"}
  • {"month"=>"6", "year"=>"2009", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"81"}
  • {"month"=>"7", "year"=>"2009", "pdf_views"=>"24", "xml_views"=>"2", "html_views"=>"103"}
  • {"month"=>"8", "year"=>"2009", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"86"}
  • {"month"=>"9", "year"=>"2009", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"89"}
  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"86"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"126"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"22", "xml_views"=>"1", "html_views"=>"88"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"41", "xml_views"=>"1", "html_views"=>"119"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"104"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"104"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"26", "xml_views"=>"2", "html_views"=>"131"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"87"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"56"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"97"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"119"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"144"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"18", "xml_views"=>"2", "html_views"=>"68"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"76"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"72"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"41"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"47"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"41"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"70"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"108"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"104"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"74"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"127"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"159"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"188"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"43", "xml_views"=>"1", "html_views"=>"175"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"130"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"135"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"20", "xml_views"=>"5", "html_views"=>"122"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"42", "xml_views"=>"0", "html_views"=>"211"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"225"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"48", "xml_views"=>"1", "html_views"=>"253"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"159"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"207"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"213"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"241"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"28", "xml_views"=>"0", "html_views"=>"216"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"261"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"206"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"228"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"216"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"225"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"32", "xml_views"=>"2", "html_views"=>"404"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"2", "html_views"=>"246"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"238"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"229"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"208"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"30", "xml_views"=>"2", "html_views"=>"265"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"25", "xml_views"=>"2", "html_views"=>"274"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"267"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"314"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"310"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"23", "xml_views"=>"2", "html_views"=>"255"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"19", "xml_views"=>"1", "html_views"=>"283"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"40", "xml_views"=>"2", "html_views"=>"355"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"40", "xml_views"=>"4", "html_views"=>"348"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"264"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"30", "xml_views"=>"1", "html_views"=>"246"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"222"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"39", "xml_views"=>"0", "html_views"=>"272"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"259"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"355"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"282"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"357"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"27", "xml_views"=>"1", "html_views"=>"317"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"273"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"40", "xml_views"=>"0", "html_views"=>"342"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"366"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"342"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"389"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"297"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"250"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"277"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"324"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"343"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"313"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"306"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"40", "xml_views"=>"0", "html_views"=>"352"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"34", "xml_views"=>"0", "html_views"=>"386"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"391"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"49", "xml_views"=>"0", "html_views"=>"398"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"398"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"55", "xml_views"=>"1", "html_views"=>"477"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"60", "xml_views"=>"0", "html_views"=>"514"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"398"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"409"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"369"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"30", "xml_views"=>"3", "html_views"=>"305"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"41", "xml_views"=>"3", "html_views"=>"300"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"41", "xml_views"=>"2", "html_views"=>"337"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"53", "xml_views"=>"3", "html_views"=>"361"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"504"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"23", "xml_views"=>"3", "html_views"=>"385"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"1", "html_views"=>"588"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"295"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"77", "xml_views"=>"3", "html_views"=>"266"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"43", "xml_views"=>"0", "html_views"=>"328"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"34", "xml_views"=>"0", "html_views"=>"300"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"286"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"38", "xml_views"=>"4", "html_views"=>"273"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"260"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"256"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"246"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"28", "xml_views"=>"0", "html_views"=>"234"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"187"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"202"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"223"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"200"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"179"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"36", "xml_views"=>"1", "html_views"=>"206"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"173"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"185"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"168"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"129"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"107"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"116"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"104"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"109"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"35", "xml_views"=>"1", "html_views"=>"95"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"84"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"136", "xml_views"=>"1", "html_views"=>"82"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"93", "xml_views"=>"1", "html_views"=>"76"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"71"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"73"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"73"}
  • {"month"=>"9", "year"=>"2020", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"67"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/449718", "https://ndownloader.figshare.com/files/449786", "https://ndownloader.figshare.com/files/449836", "https://ndownloader.figshare.com/files/449874", "https://ndownloader.figshare.com/files/449992", "https://ndownloader.figshare.com/files/450020"], "description"=>"<div><p>A monomeric variant of the red fluorescent protein eqFP611, mRuby, is described. With excitation and emission maxima at 558 nm and 605 nm, respectively, and a large Stokes shift of 47 nm, mRuby appears particularly useful for imaging applications. The protein shows an exceptional resistance to denaturation at pH extremes. Moreover, mRuby is about ten-fold brighter compared to EGFP when being targeted to the endoplasmic reticulum. The engineering process of eqFP611 revealed that the C-terminal tail of the protein acts as a natural peroxisomal targeting signal (PTS). Using an mRuby variant carrying the eqFP611-PTS, we discovered that ordered inheritance of peroxisomes is widespread during mitosis of different mammalian cell types. The ordered partitioning is realized by the formation of peroxisome clusters around the poles of the mitotic spindle and ensures that equal numbers of the organelle are inherited by the daughter cells. The unique spectral properties make mRuby the marker of choice for a multitude of cell biological applications. Moreover, the use of mRuby has allowed novel insights in the biology of organelles responsible for severe human diseases.</p></div>", "links"=>[], "tags"=>["monomeric", "fluorescent", "labeling", "subcellular", "structures"], "article_id"=>148640, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0004391.s001", "https://dx.doi.org/10.1371/journal.pone.0004391.s002", "https://dx.doi.org/10.1371/journal.pone.0004391.s003", "https://dx.doi.org/10.1371/journal.pone.0004391.s004", "https://dx.doi.org/10.1371/journal.pone.0004391.s005", "https://dx.doi.org/10.1371/journal.pone.0004391.s006"], "stats"=>{"downloads"=>4, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/mRuby_a_Bright_Monomeric_Red_Fluorescent_Protein_for_Labeling_of_Subcellular_Structures/148640", "title"=>"mRuby, a Bright Monomeric Red Fluorescent Protein for Labeling of Subcellular Structures", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2009-02-05 02:24:00"}
  • {"files"=>["https://ndownloader.figshare.com/files/909111"], "description"=>"<p>(A) <i>In vitro</i> chromophore maturation at 37°C as determined from the fluorescence emission at 605 nm (solid line: exponential fit). (B) Elution volume for concentrations of 4–30 mg/ml (0.16–1.2 mM) during gel-filtration analysis (standards for the oligomerization degree: GFP S65T, monomer; td-RFP611, dimer; eqFP611, tetramer). (C) Absorption, excitation and emission spectra (inset: fluorescence decay with a single exponential fit, yielding a lifetime of 2.6±0.1 ns). (D) Absorption spectra at various pH values (inset: absorption at 558 nm versus pH; Henderson-Hasselbalch fit reveals a pKa of 4.4).</p>", "links"=>[], "tags"=>["mruby"], "article_id"=>579565, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.g002", "stats"=>{"downloads"=>0, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characterization_of_mRuby_properties_/579565", "title"=>"Characterization of mRuby properties.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-05 02:39:25"}
  • {"files"=>["https://ndownloader.figshare.com/files/909482"], "description"=>"a<p>Product of QY and Emol compared to the brightness of EGFP (53,000 M<sup>−1</sup> cm<sup>−1</sup>×0.6) <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Patterson1\" target=\"_blank\">[41]</a>.</p>b<p>Concentration of the red chromophore deduced from the protein concentration as determined by colorimetric methods.</p>c<p>Concentration of the red chromophore determined by the alkaline denaturation method <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Gross1\" target=\"_blank\">[42]</a>.</p>d<p>Concentration of the red chromophore determined by the <i>dynamic difference method</i><a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Kredel1\" target=\"_blank\">[14]</a>.</p>e<p>Values from reference <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Kredel1\" target=\"_blank\">[14]</a>.</p>", "links"=>[], "tags"=>["properties", "egfp", "compared", "predecessors", "monomeric", "fluorescent", "proteins", "emitting", "spectral"], "article_id"=>579921, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.t001", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Fluorescence_properties_of_EGFP_compared_to_mRuby_its_predecessors_and_other_monomeric_fluorescent_proteins_emitting_in_the_orange_to_red_spectral_region_/579921", "title"=>"Fluorescence properties of EGFP compared to mRuby, its predecessors and other monomeric fluorescent proteins emitting in the orange to red spectral region.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-02-05 02:45:21"}
  • {"files"=>["https://ndownloader.figshare.com/files/909293"], "description"=>"<p>(A–C) Confocal images (Leica TCS 4Pi) of HEK293 cells co-expressing mRuby-PTS and H2B-EGFP during (A) interphase and (B) metaphase. The inset in (B) shows a magnification of a peroxisomal cluster. Tubulin fibers are labelled in green with Alexa Fluor©-488 via an anti-α-tubulin antibody (C) to reveal peroxisomal clustering at the spindle poles. Bars: 2 µm.</p>", "links"=>[], "tags"=>["clusters", "hek293"], "article_id"=>579746, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.g004", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Peroxisome_clusters_in_HEK293_cells_/579746", "title"=>"Peroxisome clusters in HEK293 cells.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-05 02:42:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/909387"], "description"=>"<p>Distribution of peroxisomes during different stages of mitosis in HeLa (upper row) and NIH3T3 cells (lower row). Peroxisomes are highlighted by mRuby-PTS. The spindle of the mitotic cells is stained with EGFP fused to a tubulin-binding protein <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Kredel1\" target=\"_blank\">[14]</a>. Images were taken 24–48 h after transfection on an Olympus IX71 microscope equipped with standard FITC and TRITC filter sets. Bar: 5 µm.</p>", "links"=>[], "tags"=>["biochemistry/drug discovery", "biochemistry/protein chemistry", "biophysics/experimental biophysical methods", "biotechnology/bioengineering", "cell biology/cell growth and division"], "article_id"=>579837, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.g005", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Inheritance_of_peroxisomes_/579837", "title"=>"Inheritance of peroxisomes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-05 02:43:57"}
  • {"files"=>["https://ndownloader.figshare.com/files/909206"], "description"=>"<p>(A) Epifluorescence image of NIH3T3 cells expressing mRuby fused to human α-tubulin. Two cells from a single image were arranged in closer proximity (B) Spinning-disk confocal image of the endoplasmic reticulum of a HeLa cell stained with ER-mRuby-KDEL. False colors encode fluorescence intensity. Bars: 2.5 µm.</p>", "links"=>[], "tags"=>["mruby", "cellular"], "article_id"=>579659, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.g003", "stats"=>{"downloads"=>0, "page_views"=>16, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Applications_of_mRuby_as_a_cellular_marker_protein_/579659", "title"=>"Applications of mRuby as a cellular marker protein.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-05 02:40:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/909028"], "description"=>"<p>(A) The eqFP dimer 1 (RFP611 T122R) <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004391#pone.0004391-Kredel1\" target=\"_blank\">[14]</a> is evenly distributed over the cell. (B) The enhanced eqFP dimer 2 (T122G, F194A) shows a granular localization. (C–F) Cells co-expressing EGFP-SKL and an enhanced monomeric eqFP611 (T122R, F194A) variant show co-localization of green and red fluorescence in the peroxisomes. (C) Phase contrast image. (D) Green-channel image acquired with a standard FITC filter set. (E) Red-channel image produced with a standard TRITC filter set. (F) Overlay image of the green and red channels. Bars: 2.5 µm.</p>", "links"=>[], "tags"=>["localization", "eqfp611", "variants", "hek293"], "article_id"=>579478, "categories"=>["Biotechnology", "Cell Biology", "Biochemistry", "Biophysics"], "users"=>["Simone Kredel", "Franz Oswald", "Karin Nienhaus", "Karen Deuschle", "Carlheinz Röcker", "Michael Wolff", "Ralf Heilker", "G. Ulrich Nienhaus", "Jörg Wiedenmann"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0004391.g001", "stats"=>{"downloads"=>2, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Subcellular_localization_of_eqFP611_variants_in_HEK293_cells_/579478", "title"=>"Subcellular localization of eqFP611 variants in HEK293 cells.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-02-05 02:37:58"}

PMC Usage Stats | Further Information

  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"33", "year"=>"2010", "pdf"=>"5", "unique-ip"=>"42", "figure"=>"13", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"64", "unique-ip"=>"49", "pdf"=>"9", "year"=>"2010", "figure"=>"16", "scanned-summary"=>"0", "supp-data"=>"16"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"70", "year"=>"2010", "pdf"=>"24", "unique-ip"=>"61", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"55", "unique-ip"=>"50", "pdf"=>"18", "year"=>"2010", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"6", "full-text"=>"96", "year"=>"2010", "pdf"=>"16", "unique-ip"=>"56", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"60", "unique-ip"=>"45", "pdf"=>"439", "year"=>"2010", "figure"=>"20", "scanned-summary"=>"0", "supp-data"=>"14"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"34", "year"=>"2010", "pdf"=>"30", "unique-ip"=>"39", "figure"=>"13", "scanned-summary"=>"0", "supp-data"=>"16"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"75", "unique-ip"=>"49", "pdf"=>"29", "year"=>"2010", "figure"=>"19", "scanned-summary"=>"0", "supp-data"=>"17"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"45", "year"=>"2010", "pdf"=>"57", "unique-ip"=>"48", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"12"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"53", "unique-ip"=>"48", "pdf"=>"18", "year"=>"2010", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"14"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"69", "year"=>"2010", "pdf"=>"21", "unique-ip"=>"63", "figure"=>"17", "scanned-summary"=>"0", "supp-data"=>"24"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"42", "unique-ip"=>"28", "pdf"=>"10", "year"=>"2010", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"59", "year"=>"2011", "pdf"=>"11", "unique-ip"=>"47", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"10"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"1", "abstract"=>"3", "full-text"=>"71", "unique-ip"=>"61", "pdf"=>"10", "year"=>"2011", "figure"=>"22", "scanned-summary"=>"0", "supp-data"=>"16"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"53", "year"=>"2011", "pdf"=>"13", "unique-ip"=>"46", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"12"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"59", "unique-ip"=>"47", "pdf"=>"17", "year"=>"2011", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"64", "year"=>"2011", "pdf"=>"25", "unique-ip"=>"49", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"72", "unique-ip"=>"52", "pdf"=>"13", "year"=>"2011", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"31"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"55", "year"=>"2011", "pdf"=>"11", "unique-ip"=>"45", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"82", "unique-ip"=>"57", "pdf"=>"4", "year"=>"2011", "figure"=>"26", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"82", "year"=>"2011", "pdf"=>"8", "unique-ip"=>"63", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"10"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"127", "unique-ip"=>"101", "pdf"=>"10", "year"=>"2011", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"9"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"160", "year"=>"2011", "pdf"=>"17", "unique-ip"=>"140", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"85", "unique-ip"=>"68", "pdf"=>"19", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"20"}
  • {"month"=>"1", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"56", "year"=>"2012", "pdf"=>"9", "unique-ip"=>"47", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"48", "unique-ip"=>"44", "pdf"=>"9", "year"=>"2012", "figure"=>"17", "scanned-summary"=>"0", "supp-data"=>"13"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"81", "year"=>"2012", "pdf"=>"32", "unique-ip"=>"67", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"17"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"123", "unique-ip"=>"113", "pdf"=>"23", "year"=>"2012", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"17"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"116", "year"=>"2012", "pdf"=>"10", "unique-ip"=>"98", "figure"=>"13", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"scanned-page-browse"=>"0", "month"=>"2", "cited-by"=>"0", "abstract"=>"11", "full-text"=>"90", "unique-ip"=>"77", "pdf"=>"53", "year"=>"2009", "figure"=>"29", "scanned-summary"=>"0", "supp-data"=>"26"}
  • {"month"=>"3", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"65", "year"=>"2009", "pdf"=>"36", "unique-ip"=>"54", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"10"}
  • {"scanned-page-browse"=>"0", "month"=>"4", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"71", "unique-ip"=>"62", "pdf"=>"36", "year"=>"2009", "figure"=>"18", "scanned-summary"=>"0", "supp-data"=>"29"}
  • {"month"=>"5", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"113", "year"=>"2009", "pdf"=>"33", "unique-ip"=>"81", "figure"=>"26", "scanned-summary"=>"0", "supp-data"=>"25"}
  • {"scanned-page-browse"=>"0", "month"=>"6", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"62", "unique-ip"=>"45", "pdf"=>"20", "year"=>"2009", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"month"=>"7", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"6", "full-text"=>"69", "year"=>"2009", "pdf"=>"22", "unique-ip"=>"59", "figure"=>"35", "scanned-summary"=>"0", "supp-data"=>"21"}
  • {"scanned-page-browse"=>"0", "month"=>"8", "cited-by"=>"0", "abstract"=>"3", "full-text"=>"65", "unique-ip"=>"54", "pdf"=>"24", "year"=>"2009", "figure"=>"29", "scanned-summary"=>"0", "supp-data"=>"18"}
  • {"month"=>"9", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"46", "year"=>"2009", "pdf"=>"20", "unique-ip"=>"41", "figure"=>"28", "scanned-summary"=>"0", "supp-data"=>"16"}
  • {"scanned-page-browse"=>"0", "month"=>"10", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"16", "unique-ip"=>"16", "pdf"=>"3", "year"=>"2009", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"81", "year"=>"2009", "pdf"=>"19", "unique-ip"=>"66", "figure"=>"46", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"54", "unique-ip"=>"43", "pdf"=>"6", "year"=>"2009", "figure"=>"24", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"45", "year"=>"2012", "pdf"=>"12", "unique-ip"=>"37", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"unique-ip"=>"43", "full-text"=>"57", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"24", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"30", "full-text"=>"37", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"3", "cited-by"=>"1", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"38", "full-text"=>"40", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"47", "full-text"=>"59", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"27", "full-text"=>"34", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"35", "full-text"=>"42", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"43", "full-text"=>"54", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"42", "full-text"=>"44", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"50", "full-text"=>"59", "pdf"=>"9", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"48", "full-text"=>"52", "pdf"=>"13", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"41", "full-text"=>"45", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"14", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"34", "full-text"=>"34", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"28", "full-text"=>"35", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"33", "full-text"=>"35", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"38", "full-text"=>"48", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"58", "full-text"=>"69", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"40", "full-text"=>"43", "pdf"=>"10", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"41", "full-text"=>"49", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"56", "full-text"=>"58", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"16", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"60", "full-text"=>"68", "pdf"=>"16", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"18", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"35", "full-text"=>"38", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"39", "full-text"=>"45", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"32", "full-text"=>"32", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"50", "full-text"=>"61", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"73", "full-text"=>"91", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"43", "full-text"=>"58", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"49", "full-text"=>"60", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"56", "full-text"=>"61", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"68", "full-text"=>"71", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"45", "full-text"=>"51", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"65", "full-text"=>"78", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"57", "full-text"=>"62", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"83", "full-text"=>"92", "pdf"=>"23", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"7", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"31", "full-text"=>"31", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"27", "full-text"=>"31", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"30", "full-text"=>"23", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"43", "full-text"=>"41", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"57", "full-text"=>"56", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"27", "full-text"=>"30", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"33", "full-text"=>"37", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"87", "full-text"=>"99", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"4", "cited-by"=>"2", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"99", "full-text"=>"83", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"9", "cited-by"=>"3", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"66", "full-text"=>"73", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"3", "cited-by"=>"2", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"74", "full-text"=>"89", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"82", "full-text"=>"90", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"27", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"71", "full-text"=>"68", "pdf"=>"18", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"58", "full-text"=>"66", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"57", "full-text"=>"68", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"62", "full-text"=>"68", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"58", "full-text"=>"64", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"45", "full-text"=>"42", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"61", "full-text"=>"66", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"27", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"59", "full-text"=>"66", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"53", "full-text"=>"57", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"47", "full-text"=>"51", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"71", "full-text"=>"76", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"54", "full-text"=>"60", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"51", "full-text"=>"63", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"66", "full-text"=>"77", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"62", "full-text"=>"65", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"26", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"63", "full-text"=>"66", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"68", "full-text"=>"76", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"83", "full-text"=>"91", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"22", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"87", "full-text"=>"96", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"42", "full-text"=>"50", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"85", "full-text"=>"86", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"23", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"81", "full-text"=>"86", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"65", "full-text"=>"69", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"62", "full-text"=>"68", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"88", "full-text"=>"91", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"71", "full-text"=>"67", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"97", "full-text"=>"96", "pdf"=>"10", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"62", "full-text"=>"68", "pdf"=>"10", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"70", "full-text"=>"69", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"68", "full-text"=>"78", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"79", "full-text"=>"82", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"52", "full-text"=>"61", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"65", "full-text"=>"72", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"55", "full-text"=>"55", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"10", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"56", "full-text"=>"58", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"53", "full-text"=>"56", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"47", "full-text"=>"49", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"46", "full-text"=>"46", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"57", "full-text"=>"68", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"46", "full-text"=>"43", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"51", "full-text"=>"53", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"25", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"40", "full-text"=>"42", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"5", "cited-by"=>"1", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"33", "full-text"=>"33", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"38", "full-text"=>"42", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"50", "full-text"=>"56", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}
  • {"unique-ip"=>"45", "full-text"=>"52", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"7"}
  • {"unique-ip"=>"43", "full-text"=>"47", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"8"}

Relative Metric

{"start_date"=>"2009-01-01T00:00:00Z", "end_date"=>"2009-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[349, 614, 744, 851, 955, 1059, 1167, 1262, 1352, 1431, 1516, 1593, 1668, 1746, 1817, 1883, 1950, 2017, 2075, 2141, 2198, 2254, 2313, 2368, 2424, 2474, 2534, 2591, 2651, 2710, 2776, 2837, 2892, 2953, 3014, 3072, 3130, 3186, 3251, 3307, 3366, 3427, 3500, 3561, 3627, 3688, 3759, 3821, 3888, 3950, 4010, 4070, 4131, 4189, 4242, 4307, 4370, 4431, 4491, 4549, 4608]}, {"subject_area"=>"/Biology and life sciences/Cell biology", "average_usage"=>[336, 588, 721, 826, 931, 1029, 1138, 1224, 1311, 1395, 1477, 1555, 1632, 1704, 1774, 1847, 1919, 1987, 2039, 2089, 2149, 2204, 2264, 2319, 2370, 2424, 2481, 2535, 2593, 2645, 2702, 2765, 2816, 2865, 2932, 2992, 3045, 3105, 3159, 3208, 3259, 3316, 3374, 3430, 3490, 3542, 3602, 3654, 3720, 3783, 3851, 3919, 3981, 4038, 4096, 4151, 4197, 4235, 4297, 4372, 4437]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[340, 575, 698, 803, 889, 974, 1077, 1169, 1245, 1318, 1398, 1468, 1540, 1608, 1679, 1748, 1819, 1877, 1937, 1999, 2044, 2100, 2148, 2198, 2250, 2306, 2357, 2414, 2458, 2517, 2572, 2636, 2690, 2749, 2799, 2861, 2914, 2970, 3026, 3102, 3143, 3237, 3303, 3373, 3441, 3500, 3553, 3608, 3679, 3733, 3791, 3856, 3908, 3962, 4033, 4096, 4149, 4187, 4229, 4281, 4336]}, {"subject_area"=>"/Physical sciences/Physics", "average_usage"=>[332, 576, 695, 791, 879, 956, 1066, 1171, 1247, 1317, 1390, 1466, 1562, 1625, 1681, 1751, 1807, 1879, 1927, 1990, 2050, 2099, 2141, 2186, 2236, 2295, 2337, 2370, 2434, 2503, 2563, 2634, 2685, 2738, 2802, 2853, 2929, 2980, 3024, 3073, 3135, 3214, 3271, 3354, 3411, 3479, 3542, 3610, 3665, 3722, 3759, 3799, 3872, 3957, 3997, 4051, 4121, 4197, 4241, 4292, 4321]}]}
Loading … Spinner
There are currently no alerts