Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in E. coli
Events
Loading … Spinner

CiteULike | Further Information

Mendeley | Further Information

{"title"=>"Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli", "type"=>"journal", "authors"=>[{"first_name"=>"Alfredo", "last_name"=>"Mendoza-Vargas", "scopus_author_id"=>"15834987800"}, {"first_name"=>"Leticia", "last_name"=>"Olvera", "scopus_author_id"=>"6505982552"}, {"first_name"=>"Maricela", "last_name"=>"Olvera", "scopus_author_id"=>"6603822476"}, {"first_name"=>"Ricardo", "last_name"=>"Grande", "scopus_author_id"=>"7003683897"}, {"first_name"=>"Leticia", "last_name"=>"Vega-Alvarado", "scopus_author_id"=>"6507289870"}, {"first_name"=>"Blanca", "last_name"=>"Taboada", "scopus_author_id"=>"6506423214"}, {"first_name"=>"Verónica", "last_name"=>"Jimenez-Jacinto", "scopus_author_id"=>"6507618500"}, {"first_name"=>"Heladia", "last_name"=>"Salgado", "scopus_author_id"=>"7006032034"}, {"first_name"=>"Katy", "last_name"=>"Juárez", "scopus_author_id"=>"6507141607"}, {"first_name"=>"Bruno", "last_name"=>"Contreras-Moreira", "scopus_author_id"=>"6602677166"}, {"first_name"=>"Araceli M.", "last_name"=>"Huerta", "scopus_author_id"=>"7004611275"}, {"first_name"=>"Julio", "last_name"=>"Collado-Vides", "scopus_author_id"=>"7004041493"}, {"first_name"=>"Enrique", "last_name"=>"Morett", "scopus_author_id"=>"6701403664"}], "year"=>2009, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"70449380939", "doi"=>"10.1371/journal.pone.0007526", "pui"=>"355609490", "pmid"=>"19838305", "scopus"=>"2-s2.0-70449380939", "issn"=>"19326203", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)"}, "id"=>"580cb503-d22f-3885-b062-762710067eba", "abstract"=>"Despite almost 40 years of molecular genetics research in Escherichia coli a major fraction of its Transcription Start Sites (TSSs) are still unknown, limiting therefore our understanding of the regulatory circuits that control gene expression in this model organism. RegulonDB (http://regulondb.ccg.unam.mx/) is aimed at integrating the genetic regulatory network of E. coli K12 as an entirely bioinformatic project up till now. In this work, we extended its aims by generating experimental data at a genome scale on TSSs, promoters and regulatory regions. We implemented a modified 5' RACE protocol and an unbiased High Throughput Pyrosequencing Strategy (HTPS) that allowed us to map more than 1700 TSSs with high precision. From this collection, about 230 corresponded to previously reported TSSs, which helped us to benchmark both our methodologies and the accuracy of the previous mapping experiments. The other ca 1500 TSSs mapped belong to about 1000 different genes, many of them with no assigned function. We identified promoter sequences and type of sigma factors that control the expression of about 80% of these genes. As expected, the housekeeping sigma(70) was the most common type of promoter, followed by sigma(38). The majority of the putative TSSs were located between 20 to 40 nucleotides from the translational start site. Putative regulatory binding sites for transcription factors were detected upstream of many TSSs. For a few transcripts, riboswitches and small RNAs were found. Several genes also had additional TSSs within the coding region. Unexpectedly, the HTPS experiments revealed extensive antisense transcription, probably for regulatory functions. The new information in RegulonDB, now with more than 2400 experimentally determined TSSs, strengthens the accuracy of promoter prediction, operon structure, and regulatory networks and provides valuable new information that will facilitate the understanding from a global perspective the complex and intricate regulatory network that operates in E. coli.", "link"=>"http://www.mendeley.com/research/genomewide-identification-transcription-start-sites-promoters-transcription-factor-binding-sites-e-c-1", "reader_count"=>241, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>15, "Researcher"=>66, "Student > Doctoral Student"=>12, "Student > Ph. D. Student"=>76, "Student > Postgraduate"=>6, "Other"=>9, "Student > Master"=>25, "Student > Bachelor"=>21, "Lecturer"=>3, "Lecturer > Senior Lecturer"=>2, "Professor"=>4}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>15, "Researcher"=>66, "Student > Doctoral Student"=>12, "Student > Ph. D. Student"=>76, "Student > Postgraduate"=>6, "Other"=>9, "Student > Master"=>25, "Student > Bachelor"=>21, "Lecturer"=>3, "Lecturer > Senior Lecturer"=>2, "Professor"=>4}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Agricultural and Biological Sciences"=>158, "Business, Management and Accounting"=>1, "Chemistry"=>3, "Computer Science"=>8, "Earth and Planetary Sciences"=>1, "Engineering"=>4, "Environmental Science"=>2, "Biochemistry, Genetics and Molecular Biology"=>41, "Materials Science"=>1, "Mathematics"=>6, "Medicine and Dentistry"=>1, "Design"=>1, "Physics and Astronomy"=>3, "Social Sciences"=>1, "Immunology and Microbiology"=>5}, "reader_count_by_subdiscipline"=>{"Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Social Sciences"=>{"Social Sciences"=>1}, "Physics and Astronomy"=>{"Physics and Astronomy"=>3}, "Mathematics"=>{"Mathematics"=>6}, "Unspecified"=>{"Unspecified"=>5}, "Environmental Science"=>{"Environmental Science"=>2}, "Design"=>{"Design"=>1}, "Engineering"=>{"Engineering"=>4}, "Chemistry"=>{"Chemistry"=>3}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>5}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>158}, "Computer Science"=>{"Computer Science"=>8}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>41}}, "reader_count_by_country"=>{"United States"=>12, "Japan"=>1, "United Kingdom"=>2, "Russia"=>1, "India"=>2, "Spain"=>1, "Canada"=>4, "Netherlands"=>2, "Vietnam"=>1, "Turkey"=>1, "Belgium"=>2, "Ireland"=>1, "Luxembourg"=>1, "Denmark"=>1, "Brazil"=>2, "Mexico"=>3, "France"=>1, "Germany"=>3}, "group_count"=>9}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/70449380939"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/70449380939?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70449380939&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=70449380939&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/70449380939", "dc:identifier"=>"SCOPUS_ID:70449380939", "eid"=>"2-s2.0-70449380939", "dc:title"=>"Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli", "dc:creator"=>"Mendoza-Vargas A.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"4", "prism:issueIdentifier"=>"10", "prism:pageRange"=>nil, "prism:coverDate"=>"2009-10-19", "prism:coverDisplayDate"=>"19 October 2009", "prism:doi"=>"10.1371/journal.pone.0007526", "citedby-count"=>"182", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Instituto de Biotecnología de la UNAM", "affiliation-city"=>"Cuernavaca", "affiliation-country"=>"Mexico"}], "pubmed-id"=>"19838305", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e7526", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true, "freetoread"=>{"value"=>[{"$"=>"all"}, {"$"=>"publisherfullgold"}, {"$"=>"repository"}, {"$"=>"repositoryvor"}, {"$"=>"repositoryam"}]}, "freetoreadLabel"=>{"value"=>[{"$"=>"All Open Access"}, {"$"=>"Gold"}, {"$"=>"Green"}]}}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0007526", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"10", "year"=>"2009", "pdf_views"=>"175", "xml_views"=>"2", "html_views"=>"490"}
  • {"month"=>"11", "year"=>"2009", "pdf_views"=>"66", "xml_views"=>"1", "html_views"=>"224"}
  • {"month"=>"12", "year"=>"2009", "pdf_views"=>"45", "xml_views"=>"1", "html_views"=>"144"}
  • {"month"=>"1", "year"=>"2010", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"137"}
  • {"month"=>"2", "year"=>"2010", "pdf_views"=>"48", "xml_views"=>"0", "html_views"=>"142"}
  • {"month"=>"3", "year"=>"2010", "pdf_views"=>"49", "xml_views"=>"0", "html_views"=>"158"}
  • {"month"=>"4", "year"=>"2010", "pdf_views"=>"82", "xml_views"=>"1", "html_views"=>"182"}
  • {"month"=>"5", "year"=>"2010", "pdf_views"=>"45", "xml_views"=>"3", "html_views"=>"174"}
  • {"month"=>"6", "year"=>"2010", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"154"}
  • {"month"=>"7", "year"=>"2010", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"151"}
  • {"month"=>"8", "year"=>"2010", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"142"}
  • {"month"=>"9", "year"=>"2010", "pdf_views"=>"31", "xml_views"=>"1", "html_views"=>"162"}
  • {"month"=>"10", "year"=>"2010", "pdf_views"=>"48", "xml_views"=>"1", "html_views"=>"148"}
  • {"month"=>"11", "year"=>"2010", "pdf_views"=>"45", "xml_views"=>"1", "html_views"=>"135"}
  • {"month"=>"12", "year"=>"2010", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"36", "xml_views"=>"2", "html_views"=>"126"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"53", "xml_views"=>"0", "html_views"=>"161"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"65", "xml_views"=>"0", "html_views"=>"215"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"126"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"34", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"83"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"106"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"133"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"59", "xml_views"=>"0", "html_views"=>"251"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"49", "xml_views"=>"0", "html_views"=>"286"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"43", "xml_views"=>"1", "html_views"=>"320"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"52", "xml_views"=>"0", "html_views"=>"278"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"57", "xml_views"=>"3", "html_views"=>"268"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"55", "xml_views"=>"1", "html_views"=>"249"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"50", "xml_views"=>"0", "html_views"=>"279"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"43", "xml_views"=>"2", "html_views"=>"270"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"58", "xml_views"=>"1", "html_views"=>"219"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"45", "xml_views"=>"0", "html_views"=>"221"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"56", "xml_views"=>"0", "html_views"=>"245"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"44", "xml_views"=>"5", "html_views"=>"225"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"42", "xml_views"=>"1", "html_views"=>"254"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"50", "xml_views"=>"0", "html_views"=>"313"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"48", "xml_views"=>"0", "html_views"=>"390"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"216"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"241"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"39", "xml_views"=>"1", "html_views"=>"209"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"40", "xml_views"=>"0", "html_views"=>"232"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"167"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"195"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"171"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"42", "xml_views"=>"0", "html_views"=>"171"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"39", "xml_views"=>"0", "html_views"=>"188"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"44", "xml_views"=>"4", "html_views"=>"231"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"35", "xml_views"=>"1", "html_views"=>"171"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"44", "xml_views"=>"2", "html_views"=>"195"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"172"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"177"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"46", "xml_views"=>"0", "html_views"=>"224"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"31", "xml_views"=>"4", "html_views"=>"249"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"25", "xml_views"=>"3", "html_views"=>"210"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"259"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"182"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"34", "xml_views"=>"0", "html_views"=>"222"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"23", "xml_views"=>"4", "html_views"=>"173"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"210"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"46", "xml_views"=>"1", "html_views"=>"218"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"29", "xml_views"=>"1", "html_views"=>"170"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"21", "xml_views"=>"2", "html_views"=>"128"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"91"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"126"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"213"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"33", "xml_views"=>"1", "html_views"=>"148"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"178"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"162"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"137"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"123"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"141"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"44", "xml_views"=>"0", "html_views"=>"167"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"169"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"112"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"25", "xml_views"=>"0", "html_views"=>"121"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"132"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"156"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"49", "xml_views"=>"0", "html_views"=>"118"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"49", "xml_views"=>"0", "html_views"=>"120"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"122"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"105"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"124"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"225"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"36", "xml_views"=>"0", "html_views"=>"273"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"352"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"446"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"283"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"25", "xml_views"=>"1", "html_views"=>"318"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"278"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"278"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"23", "xml_views"=>"1", "html_views"=>"231"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"252"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"32", "xml_views"=>"3", "html_views"=>"237"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"282"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"245"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"34", "xml_views"=>"2", "html_views"=>"307"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"251"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"193"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"194"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"80"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"80"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"60", "xml_views"=>"2", "html_views"=>"88"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"63", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"60", "xml_views"=>"4", "html_views"=>"67"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"48", "xml_views"=>"1", "html_views"=>"47"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"50"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"36", "xml_views"=>"1", "html_views"=>"61"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"66", "xml_views"=>"0", "html_views"=>"58"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"52", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"42", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"85", "xml_views"=>"0", "html_views"=>"55"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"75", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"89", "xml_views"=>"0", "html_views"=>"74"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"80", "xml_views"=>"0", "html_views"=>"80"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"73", "xml_views"=>"0", "html_views"=>"48"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"103", "xml_views"=>"0", "html_views"=>"55"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"109", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"80", "xml_views"=>"0", "html_views"=>"50"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"46", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"48", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"19", "xml_views"=>"1", "html_views"=>"97"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"41"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"42"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"54", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"42", "xml_views"=>"1", "html_views"=>"30"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"9", "year"=>"2020", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"23"}
  • {"month"=>"10", "year"=>"2020", "pdf_views"=>"31", "xml_views"=>"2", "html_views"=>"30"}
  • {"month"=>"11", "year"=>"2020", "pdf_views"=>"33", "xml_views"=>"2", "html_views"=>"45"}
  • {"month"=>"12", "year"=>"2020", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"32"}
  • {"month"=>"1", "year"=>"2021", "pdf_views"=>"34", "xml_views"=>"1", "html_views"=>"40"}
  • {"month"=>"2", "year"=>"2021", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"51"}
  • {"month"=>"3", "year"=>"2021", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"2"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/435978", "https://ndownloader.figshare.com/files/436039", "https://ndownloader.figshare.com/files/436132", "https://ndownloader.figshare.com/files/436179", "https://ndownloader.figshare.com/files/436221", "https://ndownloader.figshare.com/files/436264", "https://ndownloader.figshare.com/files/436295", "https://ndownloader.figshare.com/files/436324", "https://ndownloader.figshare.com/files/436336", "https://ndownloader.figshare.com/files/436358", "https://ndownloader.figshare.com/files/436374", "https://ndownloader.figshare.com/files/436425"], "description"=>"<div><p>Despite almost 40 years of molecular genetics research in <em>Escherichia coli</em> a major fraction of its Transcription Start Sites (TSSs) are still unknown, limiting therefore our understanding of the regulatory circuits that control gene expression in this model organism. RegulonDB (<a href=\"http://regulondb.ccg.unam.mx/\">http://regulondb.ccg.unam.mx/</a>) is aimed at integrating the genetic regulatory network of <em>E. coli</em> K12 as an entirely bioinformatic project up till now. In this work, we extended its aims by generating experimental data at a genome scale on TSSs, promoters and regulatory regions. We implemented a modified 5′ RACE protocol and an unbiased High Throughput Pyrosequencing Strategy (HTPS) that allowed us to map more than 1700 TSSs with high precision. From this collection, about 230 corresponded to previously reported TSSs, which helped us to benchmark both our methodologies and the accuracy of the previous mapping experiments. The other <em>ca</em> 1500 TSSs mapped belong to about 1000 different genes, many of them with no assigned function. We identified promoter sequences and type of σ factors that control the expression of about 80% of these genes. As expected, the housekeeping σ<sup>70</sup> was the most common type of promoter, followed by σ<sup>38</sup>. The majority of the putative TSSs were located between 20 to 40 nucleotides from the translational start site. Putative regulatory binding sites for transcription factors were detected upstream of many TSSs. For a few transcripts, riboswitches and small RNAs were found. Several genes also had additional TSSs within the coding region. Unexpectedly, the HTPS experiments revealed extensive antisense transcription, probably for regulatory functions. The new information in RegulonDB, now with more than 2400 experimentally determined TSSs, strengthens the accuracy of promoter prediction, operon structure, and regulatory networks and provides valuable new information that will facilitate the understanding from a global perspective the complex and intricate regulatory network that operates in <em>E. coli</em>.</p></div>", "links"=>[], "tags"=>["genome-wide", "transcription", "promoters", "binding", "sites"], "article_id"=>145976, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.s001", "https://dx.doi.org/10.1371/journal.pone.0007526.s002", "https://dx.doi.org/10.1371/journal.pone.0007526.s003", "https://dx.doi.org/10.1371/journal.pone.0007526.s004", "https://dx.doi.org/10.1371/journal.pone.0007526.s005", "https://dx.doi.org/10.1371/journal.pone.0007526.s006", "https://dx.doi.org/10.1371/journal.pone.0007526.s007", "https://dx.doi.org/10.1371/journal.pone.0007526.s008", "https://dx.doi.org/10.1371/journal.pone.0007526.s009", "https://dx.doi.org/10.1371/journal.pone.0007526.s010", "https://dx.doi.org/10.1371/journal.pone.0007526.s011", "https://dx.doi.org/10.1371/journal.pone.0007526.s012"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Genome_Wide_Identification_of_Transcription_Start_Sites_Promoters_and_Transcription_Factor_Binding_Sites_in_E_coli_/145976", "title"=>"Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in <em>E. coli</em>", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2009-10-19 01:39:36"}
  • {"files"=>["https://ndownloader.figshare.com/files/879235"], "description"=>"<p>a) Data selection using different databases in regulonDB; b) Rapid Amplification of cDNA Ends modified protocol. The key points to enhance the efficiency of the DMTSS protocol for massive TSSs mapping were: 1) selection of highly expressed TUs under specific growth conditions, and rational oligonucleotide design; 2) lineal amplification of cDNA; 3) PAGE separation and purification of PCR products and sequencing.</p>", "links"=>[], "tags"=>["transcription", "sites"], "article_id"=>549680, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Directed_Mapping_of_Transcription_Start_Sites_DMTSS_/549680", "title"=>"Directed Mapping of Transcription Start Sites (DMTSS).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 02:41:20"}
  • {"files"=>["https://ndownloader.figshare.com/files/879340"], "description"=>"<p>A) Electropherograms show the incorporation of dCTP, dGTP, and dATP at the 3′ end of the cDNA for precise map the TSS of the <i>ompA</i> gene (ompAp2*) <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007526#pone.0007526-Cole1\" target=\"_blank\">[51]</a>. dATP was the one that produced the most homogeneous tail. B) Sequence comparison shows the 5′ end of the different tailing reactions.</p>", "links"=>[], "tags"=>["polynucleotide", "incorporation"], "article_id"=>549781, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Analysis_of_different_3_8242_end_polynucleotide_incorporation_efficiency_/549781", "title"=>"Analysis of different 3′ end polynucleotide incorporation efficiency.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 02:43:01"}
  • {"files"=>["https://ndownloader.figshare.com/files/879440"], "description"=>"<p>A) Proximal and distal oligonucleotides were designed to prime 38 and 155 nucleotides downstream of the ATG, respectively. B) The PCR products generated with each oligonucleotide primers were separated by PAGE and purified from the gel. C) Nucleotide sequence of each PCR band after excision from the gel. The nucleotide immediately before the polynucleotide tail corresponds to the TSS. D) Comparison of the nucleotide sequences obtained with the TSS previously reported <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007526#pone.0007526-Dersch1\" target=\"_blank\">[22]</a>.</p>", "links"=>[], "tags"=>["tss"], "article_id"=>549888, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Mapping_the_TSS_of_the_hns_gene_/549888", "title"=>"Mapping the TSS of the <i>hns</i> gene.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 02:44:48"}
  • {"files"=>["https://ndownloader.figshare.com/files/879564"], "description"=>"<p>A) Proximal and distal oligonucleotides were design to prime 4 and 67 nucleotides downstream of the ATG, respectively. B) The PCR products generated with the oligonucleotide primers were separated by PAGE and purified from the gel. C) Nucleotide sequence of each PCR band after excision from the gel. The 3′ end the nucleotide immediately before the polynucleotide tail is the TSS. D) Comparison of the nucleotide sequences obtained with upstream region of <i>rpsB</i>.</p>", "links"=>[], "tags"=>["tsss"], "article_id"=>550008, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Determination_of_the_unknown_TSSs_for_rpsB_gene_/550008", "title"=>"Determination of the unknown TSSs for <i>rpsB</i> gene.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:00:08"}
  • {"files"=>["https://ndownloader.figshare.com/files/879694"], "description"=>"<p>A) The oligonucleotide primer was designed to prime 97 nucleotides downstream of the ATG. B) The A and B PCR products generated with the oligonucleotide primer were separated by PAGE and purified from the gel. C) Nucleotide sequence of each PCR band. The 3′ end the nucleotide immediately before the polynucleotide tail is the TSS. D) Comparison of the nucleotide sequences obtained with the upstream region. The previously reported TSS <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007526#pone.0007526-Byrne1\" target=\"_blank\">[52]</a> was located 34 nucleotides upstream from the ATG, while the new TSS was located at 67 nucleotides downstream.</p>", "links"=>[], "tags"=>["tsss"], "article_id"=>550140, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g005"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Mapping_the_TSSs_of_the_cysK_gene_/550140", "title"=>"Mapping the TSSs of the <i>cysK</i> gene.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:02:20"}
  • {"files"=>["https://ndownloader.figshare.com/files/879814"], "description"=>"<p>The TSSs for <i>ychH</i> (A), <i>serS</i> (B), and <i>ycbB</i> (C) genes, which code for a predicted inner membrane protein, a seryl-tRNA synthetase, and a predicted carboxypeptidase, respectively, were determined by DMTSS. The unique PCR fragments obtained by PCR for each gene were sequenced. The positions of the TSSs are indicated by arrows.</p>", "links"=>[], "tags"=>["genes", "examples", "317", "tsss", "mapped"], "article_id"=>550261, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g006"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_TSSs_mapping_for_three_genes_with_no_previously_determined_5_8242_end_as_examples_of_the_317_TSSs_mapped_in_this_work_/550261", "title"=>"TSSs mapping for three genes with no previously determined 5′ end, as examples of the 317 TSSs mapped in this work.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:04:21"}
  • {"files"=>["https://ndownloader.figshare.com/files/879982"], "description"=>"<p>Comparison of the TSSs obtained in this work with the ones in RegulonDB. Both data sets are very similar, indicating no bias in the genes selected in this work.</p>", "links"=>[], "tags"=>["tsss"], "article_id"=>550429, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g007"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Number_of_TSSs_per_gene_mapped_/550429", "title"=>"Number of TSSs per gene mapped.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:07:09"}
  • {"files"=>["https://ndownloader.figshare.com/files/880142"], "description"=>"<p>A) Multiple new TSSs were obtained for the <i>kup</i> gene, 57, 135, and 213 nucleotides upstream of the ATG. B) A new TSS for <i>hybO</i> was identified 26 nucleotides upstream of the ATG, plus the previously reported one at 102 nucleotides upstream of the ATG. C) For <i>putP</i> three TSSs out of five reported were mapped 17, 94, and 138 nucleotides upstream of the ATG.</p>", "links"=>[], "tags"=>["genetics and genomics/bioinformatics", "genetics and genomics/gene expression", "microbiology/microbial evolution and genomics", "molecular biology/bioinformatics", "molecular biology/transcription initiation and activation"], "article_id"=>550582, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g008"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_DMTSS_results_/550582", "title"=>"DMTSS results.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:09:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/880262"], "description"=>"<p>Each pyrosequencing read is displayed as an arrow below the genomic DNA. Colors represent the different growth conditions from which the sequences were obtained. Mouse over the arrows displays a box with the nucleotide sequence, the position in the genome and the position with respect to ATG of the selected gene.</p>", "links"=>[], "tags"=>["chromosome", "genoseqgrapher"], "article_id"=>550704, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g009"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Graphical_representation_of_the_E_coli_chromosome_region_of_the_tig_gene_obtained_with_the_GenoSeqGrapher_V1_0_program_/550704", "title"=>"Graphical representation of the <i>E. coli</i> chromosome region of the <i>tig</i> gene obtained with the GenoSeqGrapher V1.0 program.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:11:44"}
  • {"files"=>["https://ndownloader.figshare.com/files/880354"], "description"=>"<p>TSSs obtained by both methodologies are shown in blue.</p>", "links"=>[], "tags"=>["k-12", "chromosome", "tsss", "dmtss", "htps"], "article_id"=>550794, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g010"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Display_on_the_E_coli_K_12_chromosome_of_all_the_TSSs_obtained_in_this_work_by_DMTSS_red_and_by_HTPS_black_/550794", "title"=>"Display on the <i>E. coli</i> K-12 chromosome of all the TSSs obtained in this work by DMTSS (red) and by HTPS (black).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:13:14"}
  • {"files"=>["https://ndownloader.figshare.com/files/880451"], "description"=>"<p>The graph shows several sequences upstream of the <i>csrB</i> and <i>cspA</i> genes initiating at different positions, showing the ambiguity of the TSS in some TU.</p>", "links"=>[], "tags"=>["tsss"], "article_id"=>550897, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g011"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Multiple_TSSs_for_a_single_TU_/550897", "title"=>"Multiple TSSs for a single TU.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:14:57"}
  • {"files"=>["https://ndownloader.figshare.com/files/880536"], "description"=>"<p>The graph shows the frecuency of the starting nucleotide (adenine, guanine, cytosine and thymine) TSSs obtained by DMTSS, by HTPS, and for the TSSs with predicted promoters from the HTPS data set. AGCT in DMTSS indicates any nucleotide, see text.</p>", "links"=>[], "tags"=>["initiation"], "article_id"=>550984, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g012"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Frequency_of_each_initiation_nucleotide_/550984", "title"=>"Frequency of each initiation nucleotide.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:16:24"}
  • {"files"=>["https://ndownloader.figshare.com/files/880632"], "description"=>"<p>Data obtained in this work were compared with that of RegulonDB.</p>", "links"=>[], "tags"=>["tf", "binding", "sites", "tsss"], "article_id"=>551073, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g013"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Distance_of_the_predicted_TF_binding_sites_to_the_TSSs_described_in_Table_S1_/551073", "title"=>"Distance of the predicted TF binding sites to the TSSs described in Table S1.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:17:53"}
  • {"files"=>["https://ndownloader.figshare.com/files/880712"], "description"=>"<p>The distances of each TSS mapped to the ATG translation initiation codon is plotted (5′ UTR). Dataset obtained in this work (solid line), and in all the previously mapped TSSs in RegulonDB (dashed line). For both data sets the most frequent 5′ UTR length was between 20 to 40 nucleotides.</p>", "links"=>[], "tags"=>["untranslated"], "article_id"=>551156, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.g014"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Length_of_the_5_8242_untranslated_region_5_8242_UTR_/551156", "title"=>"Length of the 5′ untranslated region (5′ UTR).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2009-10-19 00:19:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/880803"], "description"=>"<p>Promoters identified by HTPS.</p>", "links"=>[], "tags"=>["genetics and genomics/bioinformatics", "genetics and genomics/gene expression", "microbiology/microbial evolution and genomics", "molecular biology/bioinformatics", "molecular biology/transcription initiation and activation"], "article_id"=>551242, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.t004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Promoters_identified_by_HTPS_/551242", "title"=>"Promoters identified by HTPS.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-10-19 00:20:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/880854"], "description"=>"<p>a) original control; b) fortuitously mapped; and c) later annotated.</p>", "links"=>[], "tags"=>["dmtss", "compared", "reports", "cases", "tsss"], "article_id"=>551294, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Results_obtained_with_DMTSS_compared_with_previously_reports_of_TSSs_In_the_cases_with_a_mark_additional_TSSs_were_identified_/551294", "title"=>"Results obtained with DMTSS compared with previously reports of TSSs. In the cases with a * mark, additional TSSs were identified.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-10-19 00:21:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/880904"], "description"=>"<p>The PATSER program <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007526#pone.0007526-Hertz1\" target=\"_blank\">[39]</a>, was used to search for conserved −10 elements for both sigma factors upstream of the 5′ ends located within the putative coding region. The TSSs previously reported are indicated.</p>", "links"=>[], "tags"=>["putative", "elements", "ends", "coding"], "article_id"=>551346, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.t002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Prediction_of_putative_70_and_963_38_8722_10_elements_at_the_5_8242_ends_detected_within_coding_regions_/551346", "title"=>"Prediction of putative σ<sup>70</sup> and σ<sup>38</sup> −10 elements at the 5′ ends detected within coding regions.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-10-19 00:22:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/880958"], "description"=>"<p>Promoters identified by DMTSS.</p>", "links"=>[], "tags"=>["genetics and genomics/bioinformatics", "genetics and genomics/gene expression", "microbiology/microbial evolution and genomics", "molecular biology/bioinformatics", "molecular biology/transcription initiation and activation"], "article_id"=>551391, "categories"=>["Microbiology", "Genetics", "Molecular Biology"], "users"=>["Alfredo Mendoza-Vargas", "Leticia Olvera", "Maricela Olvera", "Ricardo Grande", "Leticia Vega-Alvarado", "Blanca Taboada", "Verónica Jimenez-Jacinto", "Heladia Salgado", "Katy Juárez", "Bruno Contreras-Moreira", "Araceli M. Huerta", "Julio Collado-Vides", "Enrique Morett"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0007526.t003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Promoters_identified_by_DMTSS_/551391", "title"=>"Promoters identified by DMTSS.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2009-10-19 00:23:11"}

PMC Usage Stats | Further Information

  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"61", "unique-ip"=>"50", "pdf"=>"17", "year"=>"2010", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"68", "year"=>"2010", "pdf"=>"21", "unique-ip"=>"59", "figure"=>"25", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"69", "unique-ip"=>"63", "pdf"=>"27", "year"=>"2010", "figure"=>"22", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"60", "year"=>"2010", "pdf"=>"41", "unique-ip"=>"47", "figure"=>"39", "scanned-summary"=>"0", "supp-data"=>"15"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"2", "abstract"=>"7", "full-text"=>"60", "unique-ip"=>"51", "pdf"=>"34", "year"=>"2010", "figure"=>"25", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"5", "full-text"=>"64", "year"=>"2010", "pdf"=>"44", "unique-ip"=>"61", "figure"=>"18", "scanned-summary"=>"0", "supp-data"=>"24"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"48", "unique-ip"=>"38", "pdf"=>"34", "year"=>"2010", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"15"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"56", "year"=>"2010", "pdf"=>"40", "unique-ip"=>"49", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"37", "unique-ip"=>"38", "pdf"=>"30", "year"=>"2010", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"13"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"32", "year"=>"2010", "pdf"=>"21", "unique-ip"=>"33", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"7"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"28", "unique-ip"=>"31", "pdf"=>"20", "year"=>"2010", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"11"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"23", "year"=>"2010", "pdf"=>"13", "unique-ip"=>"18", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"18"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"38", "unique-ip"=>"36", "pdf"=>"20", "year"=>"2011", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"3"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"28", "year"=>"2011", "pdf"=>"26", "unique-ip"=>"33", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"50", "unique-ip"=>"50", "pdf"=>"38", "year"=>"2011", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"40", "year"=>"2011", "pdf"=>"27", "unique-ip"=>"29", "figure"=>"12", "scanned-summary"=>"0", "supp-data"=>"14"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"30", "unique-ip"=>"30", "pdf"=>"31", "year"=>"2011", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"31", "year"=>"2011", "pdf"=>"14", "unique-ip"=>"30", "figure"=>"19", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"1", "abstract"=>"1", "full-text"=>"30", "unique-ip"=>"30", "pdf"=>"17", "year"=>"2011", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"21", "year"=>"2011", "pdf"=>"12", "unique-ip"=>"28", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"20", "unique-ip"=>"25", "pdf"=>"16", "year"=>"2011", "figure"=>"7", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "year"=>"2011", "pdf"=>"12", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"14", "unique-ip"=>"15", "pdf"=>"7", "year"=>"2011", "figure"=>"3", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"11", "year"=>"2011", "pdf"=>"9", "unique-ip"=>"14", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"19", "unique-ip"=>"18", "pdf"=>"14", "year"=>"2012", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"2"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"26", "year"=>"2012", "pdf"=>"9", "unique-ip"=>"26", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"21", "unique-ip"=>"19", "pdf"=>"10", "year"=>"2012", "figure"=>"4", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"1", "abstract"=>"0", "full-text"=>"27", "year"=>"2012", "pdf"=>"12", "unique-ip"=>"27", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"5"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"25", "unique-ip"=>"28", "pdf"=>"26", "year"=>"2012", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"11", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"7", "full-text"=>"141", "year"=>"2009", "pdf"=>"31", "unique-ip"=>"128", "figure"=>"65", "scanned-summary"=>"0", "supp-data"=>"32"}
  • {"scanned-page-browse"=>"0", "month"=>"12", "cited-by"=>"0", "abstract"=>"4", "full-text"=>"89", "unique-ip"=>"83", "pdf"=>"21", "year"=>"2009", "figure"=>"30", "scanned-summary"=>"0", "supp-data"=>"23"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"24", "year"=>"2012", "pdf"=>"14", "unique-ip"=>"24", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"19", "full-text"=>"20", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"26", "full-text"=>"34", "pdf"=>"19", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"32", "full-text"=>"37", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"20", "full-text"=>"19", "pdf"=>"13", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"10", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"35", "full-text"=>"29", "pdf"=>"5", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"27", "full-text"=>"32", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"24", "full-text"=>"23", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"20", "full-text"=>"23", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"26", "full-text"=>"28", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"27", "full-text"=>"37", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"17", "full-text"=>"11", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"24", "full-text"=>"22", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"11", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"18", "full-text"=>"16", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"16", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"20", "full-text"=>"19", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"28", "full-text"=>"24", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"19", "full-text"=>"18", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"22", "full-text"=>"20", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"27", "full-text"=>"22", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"20", "full-text"=>"19", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"18", "full-text"=>"21", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"17", "full-text"=>"16", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"28", "full-text"=>"24", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"17", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"22", "full-text"=>"15", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"20", "full-text"=>"32", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"10", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"23", "full-text"=>"21", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"22", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"16", "full-text"=>"15", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"24", "full-text"=>"22", "pdf"=>"6", "abstract"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"48", "full-text"=>"31", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"18", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"38", "full-text"=>"16", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"19", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"20", "full-text"=>"17", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"19", "full-text"=>"16", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"21", "full-text"=>"16", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"0", "cited-by"=>"4", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"21", "full-text"=>"15", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"21", "full-text"=>"20", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"17", "full-text"=>"11", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"20", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"17", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"17", "full-text"=>"19", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"18", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"14", "full-text"=>"9", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"19", "full-text"=>"16", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"20", "full-text"=>"18", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"25", "full-text"=>"26", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"16", "full-text"=>"18", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"4", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"14", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"12", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"5", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"30", "full-text"=>"33", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"46", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"19", "full-text"=>"18", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"18", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"18", "full-text"=>"18", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"21", "full-text"=>"21", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"25", "full-text"=>"23", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"2"}
  • {"unique-ip"=>"44", "full-text"=>"38", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"34", "full-text"=>"41", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"24", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"26", "full-text"=>"28", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"12", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"52", "full-text"=>"53", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"26", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"24", "full-text"=>"22", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"35", "full-text"=>"30", "pdf"=>"10", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"27", "full-text"=>"35", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"21", "full-text"=>"21", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"16", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"37", "full-text"=>"39", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"30", "full-text"=>"29", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"46", "full-text"=>"53", "pdf"=>"15", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"30", "full-text"=>"35", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"13", "cited-by"=>"1", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"27", "full-text"=>"29", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"22", "full-text"=>"22", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"32", "full-text"=>"31", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"28", "full-text"=>"30", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"49", "full-text"=>"43", "pdf"=>"11", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"43", "full-text"=>"49", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"34", "full-text"=>"37", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"40", "full-text"=>"48", "pdf"=>"12", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"34", "full-text"=>"38", "pdf"=>"7", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}
  • {"unique-ip"=>"22", "full-text"=>"26", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"7"}
  • {"unique-ip"=>"26", "full-text"=>"28", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2020", "month"=>"8"}
  • {"unique-ip"=>"26", "full-text"=>"28", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2020", "month"=>"9"}
  • {"unique-ip"=>"37", "full-text"=>"39", "pdf"=>"8", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"14", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"10"}
  • {"unique-ip"=>"33", "full-text"=>"36", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"11"}
  • {"unique-ip"=>"26", "full-text"=>"32", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2020", "month"=>"12"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2021", "month"=>"1"}

Relative Metric

{"start_date"=>"2009-01-01T00:00:00Z", "end_date"=>"2009-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[349, 614, 744, 851, 955, 1059, 1167, 1262, 1352, 1431, 1516, 1593, 1668, 1746, 1817, 1883, 1950, 2017, 2075, 2141, 2198, 2254, 2313, 2368, 2424, 2474, 2534, 2591, 2651, 2710, 2776, 2837, 2892, 2953, 3014, 3072, 3130, 3186, 3251, 3307, 3366, 3427, 3500, 3561, 3627, 3688, 3759, 3821, 3888, 3950, 4010, 4070, 4131, 4189, 4242, 4307, 4370, 4431, 4491, 4549, 4608]}, {"subject_area"=>"/Biology and life sciences/Genetics", "average_usage"=>[366, 637, 775, 896, 999, 1118, 1230, 1322, 1416, 1516, 1602, 1685, 1767, 1849, 1914, 1982, 2049, 2120, 2185, 2246, 2303, 2363, 2409, 2473, 2535, 2599, 2655, 2717, 2777, 2842, 2906, 2977, 3021, 3088, 3144, 3199, 3253, 3317, 3379, 3456, 3508, 3567, 3634, 3716, 3781, 3853, 3911, 3974, 4040, 4118, 4170, 4218, 4285, 4341, 4404, 4467, 4527, 4584, 4631, 4689, 4725]}, {"subject_area"=>"/Biology and life sciences/Microbiology", "average_usage"=>[335, 610, 750, 871, 981, 1081, 1172, 1282, 1369, 1458, 1543, 1620, 1705, 1788, 1862, 1932, 2007, 2050, 2115, 2179, 2237, 2292, 2361, 2412, 2462, 2524, 2583, 2645, 2709, 2773, 2835, 2892, 2955, 3012, 3069, 3129, 3199, 3256, 3316, 3382, 3447, 3501, 3560, 3624, 3697, 3774, 3846, 3906, 3979, 4035, 4080, 4133, 4201, 4264, 4300, 4371, 4431, 4489, 4553, 4620, 4681]}, {"subject_area"=>"/Biology and life sciences/Molecular biology", "average_usage"=>[334, 613, 751, 863, 964, 1078, 1181, 1270, 1358, 1443, 1536, 1616, 1690, 1768, 1826, 1902, 1969, 2031, 2095, 2149, 2202, 2258, 2305, 2349, 2417, 2482, 2541, 2598, 2662, 2720, 2768, 2832, 2897, 2947, 2998, 3058, 3121, 3175, 3235, 3292, 3368, 3442, 3507, 3563, 3621, 3676, 3736, 3802, 3852, 3922, 3977, 4025, 4071, 4141, 4199, 4258, 4316, 4376, 4422, 4467, 4518]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[340, 575, 698, 803, 889, 974, 1077, 1169, 1245, 1318, 1398, 1468, 1540, 1608, 1679, 1748, 1819, 1877, 1937, 1999, 2044, 2100, 2148, 2198, 2250, 2306, 2357, 2414, 2458, 2517, 2572, 2636, 2690, 2749, 2799, 2861, 2914, 2970, 3026, 3102, 3143, 3237, 3303, 3373, 3441, 3500, 3553, 3608, 3679, 3733, 3791, 3856, 3908, 3962, 4033, 4096, 4149, 4187, 4229, 4281, 4336]}, {"subject_area"=>"/Physical sciences/Materials science", "average_usage"=>[338, 549, 702, 791, 871, 960, 1047, 1128, 1207, 1275, 1353, 1424, 1498, 1551, 1615, 1690, 1756, 1804, 1870, 1926, 1978, 2031, 2079, 2124, 2176, 2229, 2279, 2325, 2400, 2460, 2526, 2612, 2679, 2742, 2787, 2854, 2898, 2942, 2984, 3025, 3100, 3188, 3262, 3316, 3364, 3427, 3486, 3564, 3615, 3662, 3713, 3767, 3816, 3881, 3930, 3968, 4003, 4029, 4061, 4094, 4136, 4184]}]}
Loading … Spinner
There are currently no alerts