Restoration of Altered MicroRNA Expression in the Ischemic Heart with Resveratrol
Publication Date
December 23, 2010
Journal
PLOS ONE
Authors
Partha Mukhopadhyay, Subhendu Mukherjee, Kaimul Ahsan, Angshuman Bagchi, et al
Volume
5
Issue
12
Pages
e15705
DOI
https://dx.plos.org/10.1371/journal.pone.0015705
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0015705
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/21203465
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009730
Europe PMC
http://europepmc.org/abstract/MED/21203465
Web of Science
000285579200031
Scopus
78650840268
Mendeley
http://www.mendeley.com/research/restoration-altered-microrna-expression-ischemic-heart-resveratrol
Events
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Mendeley | Further Information

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CrossRef

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/810349"], "description"=>"<p>(A) Correlation of miRNA expressions between basal level and IR control heart using scatter plot: Few miRNA expressions were selected for display as shown in <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015705#pone-0015705-t001\" target=\"_blank\">table 1</a>. (B) Heatmap for cluster analyses of differentially expressed miRNA among samples: Each miRNA was represented as single bar based from their Ct values and color coding was shown below with a gradient from blue (negative and lowest Ct values) to red (positive and highest Ct values). miRNAs not detected were shown as black bars. Each column was represented sample indicated on top. (C) Principal component analyses of all samples. This multivariate analysis demonstrated the proximity of longivinex and resveratrol treated IR samples to the control (vehicle) samples. BL: Baseline; IR: Ischemia for 30 min and 2 h reperfusion; VEH: Vehicle, RESV: Resveratrol; LONG: Longevinex.</p>", "links"=>[], "tags"=>["resveratrol", "longevinex", "mirna"], "article_id"=>480721, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.g003", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Effects_of_resveratrol_and_longevinex_on_miRNA_expression_pattern_/480721", "title"=>"Effects of resveratrol and longevinex on miRNA expression pattern.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 21:38:42"}
  • {"files"=>["https://ndownloader.figshare.com/files/810502"], "description"=>"<p>(A) Ratio of ERK1/2 phosphorylation to total ERK1/2 were plotted in samples as indicated. (B) Ratio of p38 MAPK phosphorylation to total p38 MAPK were plotted in samples as described. Results are expressed as Means±SEM of six animals per group. *p<0.05 vs. Vehicle (VEH). # p<0.05 vs corresponding I/R. BL: Baseline; I/R2h: Ischemia for 30 min and 2 h reperfusion; RESV: Resveratrol; LONG: Longevinex.</p>", "links"=>[], "tags"=>["resveratrol", "longevinex", "phosphorylation", "p38"], "article_id"=>480872, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.g004", "stats"=>{"downloads"=>3, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Effects_of_resveratrol_and_longevinex_on_phosphorylation_of_ERK1_2_and_p38_MAPK_/480872", "title"=>"Effects of resveratrol and longevinex on phosphorylation of ERK1/2 and p38 MAPK.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 21:39:29"}
  • {"files"=>["https://ndownloader.figshare.com/files/810127"], "description"=>"<p>(A) Coronary flow, aortic flow and LVDP were estimated at baseline and at the indicated times of reperfusion. Infarct size and apoptosis were measured at the end of two hours of reperfusion. Results are expressed as Means±SEM of six animals per group. *p<0.05 vs. Vehicle (VEH). # p,0.05 vs corresponding I/R. BL: Baseline; I/R1h: Ischemia for 30 min and 1 h reperfusion; I/R2h: Ischemia for 30 min and 2 h reperfusion; RESV: Resveratrol; LONG: Longevinex.</p>", "links"=>[], "tags"=>["resveratrol", "longevinex", "infarct"], "article_id"=>480490, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.g001", "stats"=>{"downloads"=>2, "page_views"=>17, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Effects_of_resveratrol_and_longevinex_on_blood_flow_LVDP_dp_dt_max_infarct_size_and_apoptosis_/480490", "title"=>"Effects of resveratrol and longevinex on blood flow, LVDP, dp/dt<sub>max</sub>, infarct size and apoptosis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 21:37:22"}
  • {"files"=>["https://ndownloader.figshare.com/files/810586"], "description"=>"<p>Putative target genes for differentially expressed miRNA.</p>", "links"=>[], "tags"=>["genes", "differentially"], "article_id"=>480956, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.t002", "stats"=>{"downloads"=>8, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Putative_target_genes_for_differentially_expressed_miRNA_/480956", "title"=>"Putative target genes for differentially expressed miRNA.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 21:39:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/810231"], "description"=>"<p>(A) Box-Whisker Plot of miRNA array where outliers were shown outside the black bar and excluded for analysis. The data (Ct values) were normalized based on endogeneous genes. (B) Profile plot of miRNA array filtered on expression (20.0–100.0)th Percentile in the raw data which were normalized based on endogeneous genes. BL: Baseline; I/R2h: Ischemia for 30 min and 2 h reperfusion; VEH: Vehicle, RESV: Resveratrol; LONG: Longevinex.</p>", "links"=>[], "tags"=>["resveratrol", "longevinex", "mirna"], "article_id"=>480605, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.g002", "stats"=>{"downloads"=>1, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Effects_of_resveratrol_and_longevinex_on_global_miRNA_expression_/480605", "title"=>"Effects of resveratrol and longevinex on global miRNA expression.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 21:38:02"}
  • {"files"=>["https://ndownloader.figshare.com/files/810555"], "description"=>"<p>Top 25 miRNA were listed based its up or down regulation in IR samples.</p>", "links"=>[], "tags"=>["microrna", "basal"], "article_id"=>480927, "categories"=>["Chemistry", "Genetics"], "users"=>["Partha Mukhopadhyay", "Subhendu Mukherjee", "Kaimul Ahsan", "Angshuman Bagchi", "Pal Pacher", "Dipak K. Das"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0015705.t001", "stats"=>{"downloads"=>1, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Differential_expression_of_microRNA_expressed_in_fold_change_with_respect_to_basal_level_control_heart_sample_/480927", "title"=>"Differential expression of microRNA expressed in fold change with respect to basal level control heart sample.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 21:39:48"}

PMC Usage Stats | Further Information

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