Transcriptomics of the Bed Bug (Cimex lectularius)
Publication Date
January 19, 2011
Journal
PLOS ONE
Authors
Xiaodong Bai, Praveen Mamidala, Swapna P. Rajarapu, Susan C. Jones, et al
Volume
6
Issue
1
Pages
e16336
DOI
https://dx.plos.org/10.1371/journal.pone.0016336
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0016336
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/21283830
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023805
Europe PMC
http://europepmc.org/abstract/MED/21283830
Web of Science
000286520600041
Scopus
79251609227
Mendeley
http://www.mendeley.com/research/transcriptomics-bed-bug-cimex-lectularius
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Transcriptomics of the bed bug (Cimex lectularius)", "type"=>"journal", "authors"=>[{"first_name"=>"Xiaodong", "last_name"=>"Bai", "scopus_author_id"=>"35316833400"}, {"first_name"=>"Praveen", "last_name"=>"Mamidala", "scopus_author_id"=>"35389255500"}, {"first_name"=>"Swapna P.", "last_name"=>"Rajarapu", "scopus_author_id"=>"36057339300"}, {"first_name"=>"Susan C.", "last_name"=>"Jones", "scopus_author_id"=>"7405933636"}, {"first_name"=>"Omprakash", "last_name"=>"Mittapalli", "scopus_author_id"=>"8593251100"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "pui"=>"361190688", "doi"=>"10.1371/journal.pone.0016336", "sgr"=>"79251609227", "scopus"=>"2-s2.0-79251609227", "isbn"=>"1932-6203 (Electronic)$\\$r1932-6203 (Linking)", "pmid"=>"21283830"}, "id"=>"14cdee42-6aee-32e3-aee0-7b2f7721a62c", "abstract"=>"BACKGROUND: Bed bugs (Cimex lectularius) are blood-feeding insects poised to become one of the major pests in households throughout the United States. Resistance of C. lectularius to insecticides/pesticides is one factor thought to be involved in its sudden resurgence. Despite its high-impact status, scant knowledge exists at the genomic level for C. lectularius. Hence, we subjected the C. lectularius transcriptome to 454 pyrosequencing in order to identify potential genes involved in pesticide resistance.$\\$n$\\$nMETHODOLOGY AND PRINCIPAL FINDINGS: Using 454 pyrosequencing, we obtained a total of 216,419 reads with 79,596,412 bp, which were assembled into 35,646 expressed sequence tags (3902 contigs and 31744 singletons). Nearly 85.9{%} of the C. lectularius sequences showed similarity to insect sequences, but 44.8{%} of the deduced proteins of C. lectularius did not show similarity with sequences in the GenBank non-redundant database. KEGG analysis revealed putative members of several detoxification pathways involved in pesticide resistance. Lamprin domains, Protein Kinase domains, Protein Tyrosine Kinase domains and cytochrome P450 domains were among the top Pfam domains predicted for the C. lectularius sequences. An initial assessment of putative defense genes, including a cytochrome P450 and a glutathione-S-transferase (GST), revealed high transcript levels for the cytochrome P450 (CYP9) in pesticide-exposed versus pesticide-susceptible C. lectularius populations. A significant number of single nucleotide polymorphisms (296) and microsatellite loci (370) were predicted in the C. lectularius sequences. Furthermore, 59 putative sequences of Wolbachia were retrieved from the database.$\\$n$\\$nCONCLUSIONS: To our knowledge this is the first study to elucidate the genetic makeup of C. lectularius. This pyrosequencing effort provides clues to the identification of potential detoxification genes involved in pesticide resistance of C. lectularius and lays the foundation for future functional genomics studies.", "link"=>"http://www.mendeley.com/research/transcriptomics-bed-bug-cimex-lectularius", "reader_count"=>122, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>12, "Researcher"=>30, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>34, "Student > Postgraduate"=>5, "Student > Master"=>14, "Other"=>7, "Student > Bachelor"=>6, "Lecturer"=>3, "Professor"=>4}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>12, "Researcher"=>30, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>34, "Student > Postgraduate"=>5, "Student > Master"=>14, "Other"=>7, "Student > Bachelor"=>6, "Lecturer"=>3, "Professor"=>4}, "reader_count_by_subject_area"=>{"Unspecified"=>7, "Engineering"=>1, "Environmental Science"=>3, "Biochemistry, Genetics and Molecular Biology"=>6, "Agricultural and Biological Sciences"=>96, "Medicine and Dentistry"=>3, "Design"=>1, "Social Sciences"=>2, "Computer Science"=>1, "Decision Sciences"=>1, "Earth and Planetary Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Design"=>{"Design"=>1}, "Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Social Sciences"=>{"Social Sciences"=>2}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>96}, "Computer Science"=>{"Computer Science"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>6}, "Unspecified"=>{"Unspecified"=>7}, "Environmental Science"=>{"Environmental Science"=>3}}, "reader_count_by_country"=>{"Argentina"=>1, "United States"=>2, "Japan"=>1, "United Kingdom"=>2, "Malaysia"=>1, "Spain"=>1, "New Zealand"=>1, "Canada"=>1, "Netherlands"=>1, "Finland"=>1, "Italy"=>1, "Germany"=>1, "Indonesia"=>1}, "group_count"=>5}

CrossRef

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79251609227"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79251609227?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79251609227&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=79251609227&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/79251609227", "dc:identifier"=>"SCOPUS_ID:79251609227", "eid"=>"2-s2.0-79251609227", "dc:title"=>"Transcriptomics of the bed bug (Cimex lectularius)", "dc:creator"=>"Bai X.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"6", "prism:issueIdentifier"=>"1", "prism:pageRange"=>nil, "prism:coverDate"=>"2011-02-03", "prism:coverDisplayDate"=>"2011", "prism:doi"=>"10.1371/journal.pone.0016336", "citedby-count"=>"102", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Ohio Agricultural Research and Development Center", "affiliation-city"=>"Wooster", "affiliation-country"=>"United States"}], "pubmed-id"=>"21283830", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e16336", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0016336", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments | Further Information

Counter

  • {"month"=>"1", "year"=>"2011", "pdf_views"=>"426", "xml_views"=>"24", "html_views"=>"3271"}
  • {"month"=>"2", "year"=>"2011", "pdf_views"=>"142", "xml_views"=>"1", "html_views"=>"788"}
  • {"month"=>"3", "year"=>"2011", "pdf_views"=>"89", "xml_views"=>"1", "html_views"=>"537"}
  • {"month"=>"4", "year"=>"2011", "pdf_views"=>"65", "xml_views"=>"0", "html_views"=>"309"}
  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"55", "xml_views"=>"1", "html_views"=>"208"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"44", "xml_views"=>"1", "html_views"=>"188"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"38", "xml_views"=>"0", "html_views"=>"161"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"47", "xml_views"=>"0", "html_views"=>"202"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"40", "xml_views"=>"0", "html_views"=>"272"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"37", "xml_views"=>"0", "html_views"=>"397"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"41", "xml_views"=>"4", "html_views"=>"265"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"48", "xml_views"=>"0", "html_views"=>"205"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"35", "xml_views"=>"2", "html_views"=>"269"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"42", "xml_views"=>"0", "html_views"=>"210"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"45", "xml_views"=>"0", "html_views"=>"190"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"33", "xml_views"=>"1", "html_views"=>"198"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"176"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"160"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"41", "xml_views"=>"0", "html_views"=>"230"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"24", "xml_views"=>"6", "html_views"=>"154"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"269"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"210"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"33", "xml_views"=>"0", "html_views"=>"177"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"32", "xml_views"=>"0", "html_views"=>"214"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"180"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"157"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"269"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"24", "xml_views"=>"0", "html_views"=>"213"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"179"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"150"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"20", "xml_views"=>"1", "html_views"=>"218"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"142"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"141"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"120"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"137"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"29", "xml_views"=>"2", "html_views"=>"188"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"155"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"124"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"21", "xml_views"=>"1", "html_views"=>"128"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"153"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"3", "html_views"=>"113"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"131"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"18", "xml_views"=>"1", "html_views"=>"173"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"15", "xml_views"=>"3", "html_views"=>"136"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"86"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"176"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"79"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"109"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"107"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"87"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"76"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"86"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"135"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"200"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"139"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"166"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"228"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"102"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"117"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"139"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"100"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"87"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"87"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"112"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"109"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"22", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"68"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"55"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"55"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"1", "html_views"=>"74"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"16", "xml_views"=>"4", "html_views"=>"59"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"68"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"87"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"3", "html_views"=>"81"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"77"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"62"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"12", "xml_views"=>"1", "html_views"=>"59"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"59"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"5", "html_views"=>"56"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"18", "xml_views"=>"0", "html_views"=>"64"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"30"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"14", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"5", "html_views"=>"16"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"25"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"54"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"33"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"45"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"32"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"19", "xml_views"=>"3", "html_views"=>"25"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"49"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"61"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"2", "html_views"=>"19"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"6", "xml_views"=>"3", "html_views"=>"14"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"18"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"6"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"13", "xml_views"=>"2", "html_views"=>"21"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"4"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/805908"], "description"=>"<p>Predicted single nucleotide polymorphisms (SNP) in <i>Cimex lectularius</i> sequences.</p>", "links"=>[], "tags"=>["nucleotide", "polymorphisms"], "article_id"=>476272, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.t003", "stats"=>{"downloads"=>0, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Predicted_single_nucleotide_polymorphisms_SNP_in_Cimex_lectularius_sequences_/476272", "title"=>"Predicted single nucleotide polymorphisms (SNP) in <i>Cimex lectularius</i> sequences.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-01-19 01:44:32"}
  • {"files"=>["https://ndownloader.figshare.com/files/805695"], "description"=>"<p>(A) biological process, (B) cellular component and (C) molecular function.</p>", "links"=>[], "tags"=>["ontology", "transcriptomic", "sequences"], "article_id"=>476062, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.g004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Gene_ontology_GO_terms_for_the_transcriptomic_sequences_of_Cimex_lectularius_/476062", "title"=>"Gene ontology (GO) terms for the transcriptomic sequences of <i>Cimex lectularius.</i>", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-01-19 01:41:02"}
  • {"files"=>["https://ndownloader.figshare.com/files/805520"], "description"=>"<p>A pie chart showing species distribution of the top BLAST hits of the <i>Cimex lectularius</i> sequences to various insect species.</p>", "links"=>[], "tags"=>["hits", "sequences"], "article_id"=>475885, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.g002", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_pie_chart_showing_species_distribution_of_the_top_BLAST_hits_of_the_Cimex_lectularius_sequences_to_various_insect_species_/475885", "title"=>"A pie chart showing species distribution of the top BLAST hits of the <i>Cimex lectularius</i> sequences to various insect species.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-01-19 01:38:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/805363"], "description"=>"<p>The contig sequences are represented by shaded bars and the singleton sequences by clear bars.</p>", "links"=>[], "tags"=>["transcriptomic"], "article_id"=>475733, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.g001", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Summary_of_Cimex_lectularius_transcriptomic_sequences_/475733", "title"=>"Summary of <i>Cimex lectularius</i> transcriptomic sequences.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-01-19 01:35:33"}
  • {"files"=>["https://ndownloader.figshare.com/files/805577"], "description"=>"<p>Comparative summary of <i>Cimex lectularius</i> transcriptomic sequences with the protein sequences of <i>Drosophila melanogaster, Pediculus humanus</i> and <i>Aphis pisum</i>.</p>", "links"=>[], "tags"=>["transcriptomic", "sequences", "pediculus"], "article_id"=>475942, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.g003", "stats"=>{"downloads"=>0, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Comparative_summary_of_Cimex_lectularius_transcriptomic_sequences_with_the_protein_sequences_of_Drosophila_melanogaster_Pediculus_humanus_and_Aphis_pisum_/475942", "title"=>"Comparative summary of <i>Cimex lectularius</i> transcriptomic sequences with the protein sequences of <i>Drosophila melanogaster, Pediculus humanus</i> and <i>Aphis pisum</i>.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-01-19 01:39:02"}
  • {"files"=>["https://ndownloader.figshare.com/files/805970"], "description"=>"<p>Summary of microsatellite loci predicted in <i>Cimex lectularius</i> sequences.</p>", "links"=>[], "tags"=>["microsatellite", "loci"], "article_id"=>476337, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.t004", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Summary_of_microsatellite_loci_predicted_in_Cimex_lectularius_sequences_/476337", "title"=>"Summary of microsatellite loci predicted in <i>Cimex lectularius</i> sequences.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-01-19 01:45:37"}
  • {"files"=>["https://ndownloader.figshare.com/files/402143", "https://ndownloader.figshare.com/files/402184", "https://ndownloader.figshare.com/files/402195", "https://ndownloader.figshare.com/files/402224", "https://ndownloader.figshare.com/files/402232", "https://ndownloader.figshare.com/files/402245"], "description"=>"<div><h3>Background</h3><p>Bed bugs (<em>Cimex lectularius</em>) are blood-feeding insects poised to become one of the major pests in households throughout the United States. Resistance of <em>C. lectularius</em> to insecticides/pesticides is one factor thought to be involved in its sudden resurgence. Despite its high-impact status, scant knowledge exists at the genomic level for <em>C. lectularius</em>. Hence, we subjected the <em>C. lectularius</em> transcriptome to 454 pyrosequencing in order to identify potential genes involved in pesticide resistance.</p> <h3>Methodology and Principal Findings</h3><p>Using 454 pyrosequencing, we obtained a total of 216,419 reads with 79,596,412 bp, which were assembled into 35,646 expressed sequence tags (3902 contigs and 31744 singletons). Nearly 85.9% of the <em>C. lectularius</em> sequences showed similarity to insect sequences, but 44.8% of the deduced proteins of <em>C. lectularius</em> did not show similarity with sequences in the GenBank non-redundant database. KEGG analysis revealed putative members of several detoxification pathways involved in pesticide resistance. Lamprin domains, Protein Kinase domains, Protein Tyrosine Kinase domains and cytochrome P450 domains were among the top Pfam domains predicted for the <em>C. lectularius</em> sequences. An initial assessment of putative defense genes, including a cytochrome P450 and a glutathione-S-transferase (GST), revealed high transcript levels for the cytochrome P450 (CYP9) in pesticide-exposed versus pesticide-susceptible <em>C. lectularius</em> populations. A significant number of single nucleotide polymorphisms (296) and microsatellite loci (370) were predicted in the <em>C. lectularius</em> sequences. Furthermore, 59 putative sequences of <em>Wolbachia</em> were retrieved from the database.</p> <h3>Conclusions</h3><p>To our knowledge this is the first study to elucidate the genetic makeup of <em>C. lectularius.</em> This pyrosequencing effort provides clues to the identification of potential detoxification genes involved in pesticide resistance of <em>C. lectularius</em> and lays the foundation for future functional genomics studies.</p> </div>", "links"=>[], "tags"=>["transcriptomics"], "article_id"=>139472, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0016336.s001", "https://dx.doi.org/10.1371/journal.pone.0016336.s002", "https://dx.doi.org/10.1371/journal.pone.0016336.s003", "https://dx.doi.org/10.1371/journal.pone.0016336.s004", "https://dx.doi.org/10.1371/journal.pone.0016336.s005", "https://dx.doi.org/10.1371/journal.pone.0016336.s006"], "stats"=>{"downloads"=>0, "page_views"=>40, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Transcriptomics_of_the_Bed_Bug_Cimex_lectularius_/139472", "title"=>"Transcriptomics of the Bed Bug (<em>Cimex lectularius)</em>", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2011-01-19 02:37:52"}
  • {"files"=>["https://ndownloader.figshare.com/files/805876"], "description"=>"<p>Summary of top 15 domains predicted in <i>Cimex lectularius</i> sequences.</p>", "links"=>[], "tags"=>["15", "domains"], "article_id"=>476246, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.t001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Summary_of_top_15_domains_predicted_in_Cimex_lectularius_sequences_/476246", "title"=>"Summary of top 15 domains predicted in <i>Cimex lectularius</i> sequences.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-01-19 01:44:06"}
  • {"files"=>["https://ndownloader.figshare.com/files/805782"], "description"=>"<p>(A) mRNA levels for a cytochrome P450 (CYP9) in pesticide-exposed (blue bars) and pesticide-susceptible populations (red bars). (B) mRNA levels for a glutathione-<i>S</i>-transferase (GST) in pesticide-exposed (blue bars) and pesticide-susceptible populations (red bars). An EF-1alpha was used as the internal reference gene. Standard error of the mean for three technical replicates is represented by the error bars.</p>", "links"=>[], "tags"=>["pcr", "genes", "early-", "late-instar", "nymphs"], "article_id"=>476147, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.g005", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Quantitative_PCR_analysis_of_candidate_defense_genes_in_Cimex_lectularius_early_and_late_instar_nymphs_and_adults_/476147", "title"=>"Quantitative PCR analysis of candidate defense genes in <i>Cimex lectularius</i> early- and late-instar nymphs and adults.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-01-19 01:42:27"}
  • {"files"=>["https://ndownloader.figshare.com/files/805938"], "description"=>"<p>Genes of interest in <i>Cimex lectularius</i>.</p>", "links"=>[], "tags"=>["genetics and genomics", "microbiology", "physiology"], "article_id"=>476306, "categories"=>["Physiology", "Genetics", "Microbiology"], "users"=>["Xiaodong Bai", "Praveen Mamidala", "Swapna P. Rajarapu", "Susan C. Jones", "Omprakash Mittapalli"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0016336.t002", "stats"=>{"downloads"=>0, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Genes_of_interest_in_Cimex_lectularius_/476306", "title"=>"Genes of interest in <i>Cimex lectularius</i>.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-01-19 01:45:06"}

PMC Usage Stats | Further Information

  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"47", "year"=>"2011", "pdf"=>"24", "unique-ip"=>"51", "figure"=>"13", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"5", "full-text"=>"64", "unique-ip"=>"60", "pdf"=>"33", "year"=>"2011", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"6"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"7", "full-text"=>"38", "year"=>"2011", "pdf"=>"27", "unique-ip"=>"46", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"38", "unique-ip"=>"35", "pdf"=>"15", "year"=>"2011", "figure"=>"10", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"24", "year"=>"2011", "pdf"=>"15", "unique-ip"=>"25", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"22", "unique-ip"=>"24", "pdf"=>"10", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"63", "year"=>"2011", "pdf"=>"21", "unique-ip"=>"50", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"9"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"48", "unique-ip"=>"43", "pdf"=>"9", "year"=>"2011", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"41", "year"=>"2011", "pdf"=>"14", "unique-ip"=>"38", "figure"=>"5", "scanned-summary"=>"0", "supp-data"=>"8"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"30", "unique-ip"=>"33", "pdf"=>"8", "year"=>"2011", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"29", "year"=>"2011", "pdf"=>"4", "unique-ip"=>"25", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"3", "abstract"=>"1", "full-text"=>"45", "unique-ip"=>"38", "pdf"=>"15", "year"=>"2012", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"28", "year"=>"2012", "pdf"=>"15", "unique-ip"=>"25", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"1"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"32", "unique-ip"=>"31", "pdf"=>"14", "year"=>"2012", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"22", "year"=>"2012", "pdf"=>"16", "unique-ip"=>"26", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"4"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"15", "unique-ip"=>"18", "pdf"=>"9", "year"=>"2012", "figure"=>"0", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"24", "year"=>"2012", "pdf"=>"7", "unique-ip"=>"22", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"21", "full-text"=>"23", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"25", "full-text"=>"26", "pdf"=>"11", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"4", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"0", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"11", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"31", "full-text"=>"30", "pdf"=>"7", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"30", "full-text"=>"27", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"22", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"18", "full-text"=>"26", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"2", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"9", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"12", "full-text"=>"13", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"16", "full-text"=>"15", "pdf"=>"7", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"12", "full-text"=>"14", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"17", "full-text"=>"20", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"21", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"17", "cited-by"=>"4", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"18", "full-text"=>"18", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"3", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"18", "full-text"=>"20", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"18", "full-text"=>"12", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"14", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"16", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"8", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"20", "full-text"=>"18", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"3", "full-text"=>"1", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"13", "full-text"=>"6", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"9", "full-text"=>"11", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"7", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"22", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"4", "cited-by"=>"3", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"3", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"14", "full-text"=>"17", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"19", "full-text"=>"19", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"16", "full-text"=>"11", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"9", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"17", "full-text"=>"25", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"15", "full-text"=>"17", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"36", "full-text"=>"37", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"35", "full-text"=>"39", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"1", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"34", "full-text"=>"49", "pdf"=>"9", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"21", "full-text"=>"31", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}

Relative Metric

{"start_date"=>"2011-01-01T00:00:00Z", "end_date"=>"2011-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences", "average_usage"=>[304, 568, 702, 818, 927, 1027, 1118, 1206, 1285, 1357, 1427, 1500, 1564, 1636, 1705, 1773, 1840, 1909, 1974, 2039, 2106, 2170, 2234, 2296, 2358, 2423, 2484, 2546, 2606, 2673, 2734, 2795, 2857, 2921, 2984, 3046, 3100]}, {"subject_area"=>"/Biology and life sciences/Agriculture", "average_usage"=>[308, 573, 694, 810, 910, 993, 1084, 1153, 1231, 1302, 1368, 1447, 1509, 1581, 1659, 1737, 1803, 1867, 1937, 2011, 2067, 2142, 2196, 2260, 2318, 2376, 2413, 2492, 2584, 2650, 2729, 2803, 2868, 2929, 3006, 3082, 3146]}, {"subject_area"=>"/Biology and life sciences/Computational biology", "average_usage"=>[348, 636, 778, 900, 1011, 1120, 1220, 1303, 1392, 1471, 1554, 1628, 1704, 1776, 1855, 1934, 2016, 2084, 2149, 2232, 2303, 2379, 2465, 2539, 2593, 2657, 2722, 2786, 2856, 2918, 2989, 3057, 3124, 3185, 3234, 3300, 3343]}, {"subject_area"=>"/Biology and life sciences/Genetics", "average_usage"=>[308, 576, 718, 839, 960, 1061, 1156, 1249, 1331, 1408, 1484, 1558, 1625, 1698, 1767, 1842, 1912, 1990, 2058, 2128, 2183, 2259, 2317, 2378, 2436, 2488, 2552, 2627, 2692, 2759, 2820, 2881, 2940, 3001, 3061, 3117, 3164]}, {"subject_area"=>"/Biology and life sciences/Molecular biology", "average_usage"=>[295, 553, 688, 802, 914, 1017, 1108, 1194, 1278, 1351, 1419, 1500, 1570, 1633, 1712, 1774, 1839, 1903, 1970, 2033, 2101, 2162, 2228, 2291, 2352, 2418, 2486, 2547, 2610, 2680, 2737, 2799, 2859, 2919, 2974, 3029, 3082]}]}
Loading … Spinner
There are currently no alerts