Finding Complex Biological Relationships in Recent PubMed Articles Using Bio-LDA
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{"title"=>"Finding complex biological Relationships in recent PubMed articles using Bio-LDA", "type"=>"journal", "authors"=>[{"first_name"=>"Huijun", "last_name"=>"Wang", "scopus_author_id"=>"36138910900"}, {"first_name"=>"Ying", "last_name"=>"Ding", "scopus_author_id"=>"56427243000"}, {"first_name"=>"Jie", "last_name"=>"Tang", "scopus_author_id"=>"12241636500"}, {"first_name"=>"Xiao", "last_name"=>"Dong", "scopus_author_id"=>"36630244300"}, {"first_name"=>"Bing", "last_name"=>"He", "scopus_author_id"=>"55456319800"}, {"first_name"=>"Judy", "last_name"=>"Qiu", "scopus_author_id"=>"36185905500"}, {"first_name"=>"David J.", "last_name"=>"Wild", "scopus_author_id"=>"13102874300"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"doi"=>"10.1371/journal.pone.0017243", "sgr"=>"79952940974", "isbn"=>"10.1371/journal.pone.0017243", "pmid"=>"21448266", "issn"=>"19326203", "arxiv"=>"1103.5181", "scopus"=>"2-s2.0-79952940974", "pui"=>"361490487"}, "id"=>"4778c45d-8989-336c-9e33-55a0fe43e1f0", "abstract"=>"The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the discovery of recent information concerning genes, diseases, compounds and the interactions between them. In this paper, we describe an algorithm called Bio-LDA that uses extracted biological terminology to automatically identify latent topics, and provides a variety of measures to uncover putative relations among topics and bio-terms. Relationships identified using those approaches are combined with existing data in life science datasets to provide additional insight. Three case studies demonstrate the utility of the Bio-LDA model, including association predication, association search and connectivity map generation. This combined approach offers new opportunities for knowledge discovery in many areas of biology including target identification, lead hopping and drug repurposing.", "link"=>"http://www.mendeley.com/research/finding-complex-biological-relationships-recent-pubmed-articles-using-biolda", "reader_count"=>77, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>5, "Researcher"=>23, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>21, "Student > Postgraduate"=>3, "Student > Master"=>6, "Other"=>6, "Student > Bachelor"=>5, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>5, "Professor > Associate Professor"=>5, "Researcher"=>23, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>21, "Student > Postgraduate"=>3, "Student > Master"=>6, "Other"=>6, "Student > Bachelor"=>5, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>6, "Engineering"=>3, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>3, "Agricultural and Biological Sciences"=>24, "Medicine and Dentistry"=>3, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Physics and Astronomy"=>1, "Chemistry"=>2, "Social Sciences"=>2, "Computer Science"=>30, "Linguistics"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>3}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Chemistry"=>{"Chemistry"=>2}, "Social Sciences"=>{"Social Sciences"=>2}, "Physics and Astronomy"=>{"Physics and Astronomy"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>24}, "Computer Science"=>{"Computer Science"=>30}, "Linguistics"=>{"Linguistics"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>3}, "Unspecified"=>{"Unspecified"=>6}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"Sweden"=>1, "United States"=>5, "Luxembourg"=>1, "Italy"=>1, "United Kingdom"=>1, "France"=>2, "Australia"=>2, "Portugal"=>1, "Germany"=>1, "India"=>1}, "group_count"=>4}

Scopus | Further Information

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Figshare

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Relative Metric

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