The Populus Class III HD ZIP Transcription Factor POPCORONA Affects Cell Differentiation during Secondary Growth of Woody Stems
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{"title"=>"The populus class III HD ZIP transcription factor popcorona affects cell differentiation during secondary growth of woody stems", "type"=>"journal", "authors"=>[{"first_name"=>"Juan", "last_name"=>"Du", "scopus_author_id"=>"57198429106"}, {"first_name"=>"Eriko", "last_name"=>"Miura", "scopus_author_id"=>"16744347300"}, {"first_name"=>"Marcel", "last_name"=>"Robischon", "scopus_author_id"=>"10440322200"}, {"first_name"=>"Ciera", "last_name"=>"Martinez", "scopus_author_id"=>"37005944400"}, {"first_name"=>"Andrew", "last_name"=>"Groover", "scopus_author_id"=>"6603467465"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-79952215358", "sgr"=>"79952215358", "issn"=>"19326203", "doi"=>"10.1371/journal.pone.0017458", "pmid"=>"21386988", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "pui"=>"361364906"}, "id"=>"302c1224-053a-3435-b76d-7cbafe41a0ef", "abstract"=>"The developmental mechanisms regulating cell differentiation and patterning during the secondary growth of woody tissues are poorly understood. Class III HD ZIP transcription factors are evolutionarily ancient and play fundamental roles in various aspects of plant development. Here we investigate the role of a Class III HD ZIP transcription factor, POPCORONA, during secondary growth of woody stems. Transgenic Populus (poplar) trees expressing either a miRNA-resistant POPCORONA or a synthetic miRNA targeting POPCORONA were used to infer function of POPCORONA during secondary growth. Whole plant, histological, and gene expression changes were compared for transgenic and wild-type control plants. Synthetic miRNA knock down of POPCORONA results in abnormal lignification in cells of the pith, while overexpression of a miRNA-resistant POPCORONA results in delayed lignification of xylem and phloem fibers during secondary growth. POPCORONA misexpression also results in coordinated changes in expression of genes within a previously described transcriptional network regulating cell differentiation and cell wall biosynthesis, and hormone-related genes associated with fiber differentiation. POPCORONA illustrates another function of Class III HD ZIPs: regulating cell differentiation during secondary growth.", "link"=>"http://www.mendeley.com/research/populus-class-iii-hd-zip-transcription-factor-popcorona-affects-cell-differentiation-during-secondar", "reader_count"=>43, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>6, "Researcher"=>7, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>2, "Student > Master"=>4, "Other"=>1, "Student > Bachelor"=>1, "Lecturer"=>1, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>6, "Researcher"=>7, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>16, "Student > Postgraduate"=>2, "Student > Master"=>4, "Other"=>1, "Student > Bachelor"=>1, "Lecturer"=>1, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Biochemistry, Genetics and Molecular Biology"=>2, "Agricultural and Biological Sciences"=>39, "Medicine and Dentistry"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>39}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>1}}, "reader_count_by_country"=>{"Norway"=>1, "United States"=>1, "United Kingdom"=>1, "France"=>1, "India"=>1}, "group_count"=>2}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/795109"], "description"=>"<p><i>PCN</i> expression levels were detected by Quantitative Real Time PCR (<a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017458#s4\" target=\"_blank\">Materials and Methods</a>). Relative expression levels (mean ± SE) were calculated from triplicate qRT-PCR reactions of independent RNA samples for each transgenic and the wild-type prepared from different batches of two month-old plants. T test (P<0.05) comparison showed significant differences of expression in all transgenics compared to the wild-types. (a) Comparison <i>PCN</i> transcripts in wild-type and <i>35S::PCN-miRNAd</i> gain of function plants. (b) Comparison <i>PCN</i> transcripts in wild-type and <i>35S::miRNA-PCN</i> plants.</p>", "links"=>[], "tags"=>["levels", "knockdown", "transgenic", "plants", "wild-type"], "article_id"=>465472, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g004", "stats"=>{"downloads"=>0, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_PCN_expression_levels_in_PCN_35S_PCN_miRNAd_gain_of_function_and_35S_miRNA_PCN_knockdown_transgenic_plants_relative_to_wild_type_controls_/465472", "title"=>"<i>PCN</i> expression levels in <i>PCN 35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i> knockdown transgenic plants relative to wild-type controls.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:31:12"}
  • {"files"=>["https://ndownloader.figshare.com/files/795742"], "description"=>"a.<p>JGI gene accession refers to the accession number assigned by the Joint Genome Institute (<a href=\"http://genome.jgi-psf.org\" target=\"_blank\">http://genome.jgi-psf.org</a>).</p>b.<p>Fold Change is expressed as the ratio of gene expression in <i>PCN</i> gain of function transgenenics to wild type control.</p>c.<p>Arabidopsis refers to the accession number of the best Arabidopsis BLAST return using the JGI gene model as query.</p>d.<p>Definition line is from the Arabidopsis accession at TAIR (<a href=\"http://www.arabidopsis.org\" target=\"_blank\">http://www.arabidopsis.org</a>).</p><p>* Transcript level differences confirmed by qRT-PCR.</p>", "links"=>[], "tags"=>["down-regulated", "pcn", "transgenics"], "article_id"=>466112, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.t002", "stats"=>{"downloads"=>3, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Genes_up_or_down_regulated_in_PCN_transgenics_involved_in_hormone_related_processes_/466112", "title"=>"Genes up or down-regulated in PCN transgenics involved in hormone related processes.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-28 01:41:52"}
  • {"files"=>["https://ndownloader.figshare.com/files/794654"], "description"=>"<p>Bootstrap support values above 50% are presented above branches and Bayesian support values above 0.50 are presented below branches, where * indicates maximum 1.00 support. Black squares indicate major duplication events, while the empty square represents evidence of a duplication event without bootstrap support. Major clades are presented by longitudinal lines to the right of the tree, where solid lines represent fully supported monophyletic clades (PHB, C8, and CNA) and dashed lines indicate clade supported by Bayesian, but not bootstrap support. Black triangles represent where the <i>AtHB8, AlHB8, MgHB7</i> clade is supported according to Bayesian analysis. Species abbreviations: <i>At</i>, <i>Arabidopsis thaliana; Bd, Brachypodium distachyon; Al, Arabidopsis lyrata; Cp, Carica papaya; Cs, Cucumis sativus; Gm, Glycine max; Me, Manihot esculenta; Mt, Medicago truncatula; Mg, Mimulus guttatus; Os, Oryzas sativa; Pt, Populus trichocarpa; Pp, Physcomitrella patens; Rc, Ricinus communis; Sm, Selanginella moellendorffii, Sb, Sorghum bicolor; Vv, Vitis vinifera; Zm, Zea mays.</i></p>", "links"=>[], "tags"=>["relationships", "iii", "hd", "zip", "plants", "parsimony"], "article_id"=>465019, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g001", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Phylogenetic_relationships_among_Class_III_HD_ZIP_gene_family_in_land_plants_determined_using_maximum_parsimony_analysis_/465019", "title"=>"Phylogenetic relationships among Class III HD ZIP gene family in land plants determined using maximum parsimony analysis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:23:39"}
  • {"files"=>["https://ndownloader.figshare.com/files/795560"], "description"=>"<p>(a) Comparison of number of phloem fibers in the bottom internodes of wild-type, <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i>. (b) Comparison of number of lignified xylem cell layers in the bottom internodes of wild-type, <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i>. (c) Comparison of number of lignified pith cells in the bottom internodes of wild-type, <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i>. Relative expression levels (mean ± SE) were calculated from three cross-sections of the bottom internodes of three independent wild type plants, three <i>miRNAd</i> gain of function transgenics, three 35S::PCN-miRNAd transgenics prepared from different batches of two month-old plants.</p>", "links"=>[], "tags"=>["phenotypes", "internode", "knockdown"], "article_id"=>465928, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g007", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Quantification_of_phenotypes_in_bottom_internode_of_35S_PCN_miRNAd_gain_of_function_and_35S_miRNA_PCN_knockdown_transgenics_/465928", "title"=>"Quantification of phenotypes in bottom internode of <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i> knockdown transgenics.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:38:48"}
  • {"files"=>["https://ndownloader.figshare.com/files/795256"], "description"=>"<p>(a) Wild-type plants (2 months old). (b) <i>PCN 35S::PCN-miRNAd</i> gain of function (2 months old) plants have changes to plant architecture, shorter plants length, darker green color in leaf. (c) <i>35S::miRNA-PCN</i> knockdown plants (2 month old) have no strong differences from the wild-type. Bar = 2.5cm.</p>", "links"=>[], "tags"=>["knockdown", "plants", "compared", "wild-type"], "article_id"=>465621, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g005", "stats"=>{"downloads"=>0, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Phenotypes_of_PCN_35S_PCN_miRNAd_gain_of_function_and_35S_miRNA_PCN_knockdown_plants_compared_to_wild_type_controls_/465621", "title"=>"Phenotypes of <i>PCN 35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i> knockdown plants compared to wild-type controls.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:33:41"}
  • {"files"=>["https://ndownloader.figshare.com/files/794916"], "description"=>"<p>Antisense <i>PCN</i> (first and second columns), sense negative control (third column), and positive control (fourth column) probes were hybridized to stem sections from two month old tissue culture grown trees. (a) Section from first elongating internode hybridized with antisense <i>PCN</i> probe. <i>PCN</i> is expressed broadly during primary growth, with strongest expression associated with procambium. (b) Higher magnification of first elongating internode hybridized with antisense <i>PCN</i> probe. (c) Section from first elongating internode hybridized with sense <i>PCN</i> probe (negative control), showing minimal background hybridization. (d) Section from first elongating internode hybridized with antisense pop50S probe (positive control). (e) Section from the fourth internode, hybridized with antisense <i>PCN</i> probe. <i>PCN</i> is expressed broadly in the cambial zone, and strongly in differentiating xylem. (f) Higher magnification of (e). (g) Section from the fourth internode hybridized with negative control sense <i>PCN</i> probe. (h) Section from fourth internode hybridized with positive control antisense pop50S probe. (i) Section from seventh internode hybridized with antisense <i>PCN</i> probe. <i>PCN</i> expression is mostly associated with differentiating xylem cells and lightly in cambial zone. (j) Higher magnification of (i). (k) Section from seventh internode hybridized with sense <i>PCN</i> probe (negative control). (l) Section from seventh internode hybridized with positive control antisense pop50S probe. (m) Section from the base internode hybridized with antisense <i>PCN</i> probe. <i>PCN</i> expression is largely limited to the differentiating xylem cells and cambial zone. (n) Higher magnification of (m). (o) Section from the base internode hybridized with sense <i>PCN</i> probe (negative control). (p) Section from the base internode hybridized with positive control antisense pop50S probe. Cambial zone (Ca), Phloem fiber (Pf), Procambium (Pc), Ray (r), Xylem (Xy), Bar = 100 µm.</p>", "links"=>[], "tags"=>["revealed"], "article_id"=>465286, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g003", "stats"=>{"downloads"=>1, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Expression_of_PCN_during_Populus_stem_development_revealed_by_whole_mount_in_situ_hybridization_/465286", "title"=>"Expression of <i>PCN</i> during <i>Populus</i> stem development revealed by whole mount <i>in situ</i> hybridization.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:28:06"}
  • {"files"=>["https://ndownloader.figshare.com/files/795398"], "description"=>"<p>(a) Section from fourth internode of wild-type <i>Populus</i> stem during primary growth. (b) Section from seventh internode of wild-type <i>Populus</i> stem during transition to secondary growth, showing secondary xylem tissue formation. (c) Section from bottom internode of wild-type <i>Populus</i> stem showing secondary phloem fibers and secondary xylem tissue. (d) Lower magnification view of bottom internode of wild-type stem. (e) Section from fourth internode of <i>35S::PCN-miRNAd</i> gain of function <i>Populus</i> stem during primary growth, showing increased cambium cell layers. (f) Section from seventh internode of <i>35S::PCN-miRNAd</i> gain of function <i>Populus</i> stem during transition to secondary growth, showing delayed secondary xylem formation. (g) Section from bottom internode of <i>35S::PCN-miRNAd</i> gain of function <i>Populus</i> stem showing no lignified phloem fibers formation and decreased xylem tissue. (h) Lower magnification of section from bottom internode of <i>35S::PCN-miRNAd</i> gain of function <i>Populus</i> stem showing no lignified phloem fibers formation and decreased xylem tissue. (i) Section from fourth internode of <i>35S::miRNA-PCN</i> knockdown <i>Populus</i> stem showing early formed lignified phloem fibers and xylem cells by comparing with the wild-type. (j) Section from seventh internode of <i>35S::miRNA-PCN</i> knockdown <i>Populus</i> stem showing increased secondary phloem fibers and xylem tissue formation by comparing with the wild-type. (k) Section from bottom internode of <i>35S::miRNA-PCN</i> knockdown <i>Populus</i> stem showing ectopic lignifications in pith cells. (l) Lower magnification of section from bottom internode of <i>35S::miRNA-PCN</i> knockdown <i>Populus</i> stem showing ectopic lignifications in pith cells. Cambial zone (Ca), Phloem (Ph), Phloem fiber (Pf), Xylem (Xy), Bar = 100 µm.</p>", "links"=>[], "tags"=>["sections", "stems", "wild-type", "knockdown"], "article_id"=>465761, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g006", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Transverse_sections_of_stems_from_two_month_old_wild_type_and_35S_PCN_miRNAd_gain_of_function_and_35S_miRNA_PCN_knockdown_Populus_/465761", "title"=>"Transverse sections of stems from two month old wild-type and <i>35S::PCN-miRNAd</i> gain of function and <i>35S::miRNA-PCN</i> knockdown <i>Populus</i>.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:36:01"}
  • {"files"=>["https://ndownloader.figshare.com/files/795674"], "description"=>"a.<p>Accession number assigned by the Joint Genome Institute (<a href=\"http://genome.jgi-psf.org\" target=\"_blank\">http://genome.jgi-psf.org</a>).</p>b.<p>Fold Change is expressed as the ratio of gene expression in <i>PCN</i> gain of function transgenenics to wild type control.</p>c.<p>Accession number of the best Arabidopsis BLAST return using the JGI gene model as query.</p>d.<p>Definition line is from the Arabidopsis accession at TAIR (<a href=\"http://www.arabidopsis.org\" target=\"_blank\">http://www.arabidopsis.org</a>).</p><p>* Transcript level differences confirmed by qRT-PCR.</p>", "links"=>[], "tags"=>["factors", "mis-regulated", "pcn"], "article_id"=>466045, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.t001", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Transcription_factors_mis_regulated_in_PCN_transgenics_/466045", "title"=>"Transcription factors mis-regulated in PCN transgenics.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-28 01:40:45"}
  • {"files"=>["https://ndownloader.figshare.com/files/397568", "https://ndownloader.figshare.com/files/397576", "https://ndownloader.figshare.com/files/397590"], "description"=>"<div><p>The developmental mechanisms regulating cell differentiation and patterning during the secondary growth of woody tissues are poorly understood. Class III HD ZIP transcription factors are evolutionarily ancient and play fundamental roles in various aspects of plant development. Here we investigate the role of a Class III HD ZIP transcription factor, POPCORONA, during secondary growth of woody stems. Transgenic <em>Populus</em> (poplar) trees expressing either a miRNA-resistant <em>POPCORONA</em> or a synthetic miRNA targeting <em>POPCORONA</em> were used to infer function of <em>POPCORONA</em> during secondary growth. Whole plant, histological, and gene expression changes were compared for transgenic and wild-type control plants. Synthetic miRNA knock down of <em>POPCORONA</em> results in abnormal lignification in cells of the pith, while overexpression of a miRNA-resistant <em>POPCORONA</em> results in delayed lignification of xylem and phloem fibers during secondary growth. <em>POPCORONA</em> misexpression also results in coordinated changes in expression of genes within a previously described transcriptional network regulating cell differentiation and cell wall biosynthesis, and hormone-related genes associated with fiber differentiation. <em>POPCORONA</em> illustrates another function of Class III HD ZIPs: regulating cell differentiation during secondary growth.</p> </div>", "links"=>[], "tags"=>["iii", "hd", "zip", "transcription", "affects", "differentiation", "woody", "stems"], "article_id"=>138538, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Cell Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0017458.s001", "https://dx.doi.org/10.1371/journal.pone.0017458.s002", "https://dx.doi.org/10.1371/journal.pone.0017458.s003"], "stats"=>{"downloads"=>11, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/The_Populus_Class_III_HD_ZIP_Transcription_Factor_POPCORONA_Affects_Cell_Differentiation_during_Secondary_Growth_of_Woody_Stems/138538", "title"=>"The <em>Populus</em> Class III HD ZIP Transcription Factor <em>POPCORONA</em> Affects Cell Differentiation during Secondary Growth of Woody Stems", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2011-02-28 02:22:18"}
  • {"files"=>["https://ndownloader.figshare.com/files/794741"], "description"=>"<p>Relative expression of <i>PCN</i> and paralog Pt-ATHB.11 in apices, leaves, roots, and stem was determined using Quantitative Real Time PCR (QRT-PCR) of two month old tissue culture grown <i>Populus tremula x alba</i>. <i>PCN</i> and paralog Pt-ATHB.11 are expressed in all tissues assayed, and are highly expressed in shoot apexes and stem tissue with active cambium. Stem tissue samples were confirmed to have a vascular cambium by phloroglucinol staining of secondary xylem. Relative expression (Mean ± SE) was calculated from triplicate QRT-PCR reactions of independent RNA samples prepared from different trees.</p>", "links"=>[], "tags"=>["paralog", "assayed", "quantitative"], "article_id"=>465110, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.g002", "stats"=>{"downloads"=>1, "page_views"=>22, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Expression_of_PCN_Fig_2a_and_PCN_paralog_Pt_ATHB_11_Fig_2b_in_organs_as_assayed_by_Quantitative_Real_Time_PCR_/465110", "title"=>"Expression of <i>PCN</i> (Fig. 2a) and <i>PCN</i> paralog Pt-ATHB.11 (Fig. 2b) in organs, as assayed by Quantitative Real Time PCR.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2011-02-28 01:25:10"}
  • {"files"=>["https://ndownloader.figshare.com/files/795712"], "description"=>"a.<p>Accession number assigned to the assayed gene model by the Joint Genome Institute (<a href=\"http://genome.jgi-psf.org\" target=\"_blank\">http://genome.jgi-psf.org</a>).</p>b.<p>Fold Change is expressed as the ratio of gene expression in PCN gain of function transgenenics to wild type control.</p>c.<p>Accession number of the best Arabidopsis BLAST return using the JGI gene model as query.</p>d.<p>Definition line is from the Arabidopsis accession at TAIR (<a href=\"http://www.arabidopsis.org\" target=\"_blank\">http://www.arabidopsis.org</a>).</p><p>* Transcript level differences confirmed by qRT-PCR.</p>", "links"=>[], "tags"=>["down-regulated", "pcn", "transgenics", "synthesis"], "article_id"=>466081, "categories"=>["Biotechnology", "Genetics", "Developmental Biology", "Plant Biology"], "users"=>["Juan Du", "Eriko Miura", "Marcel Robischon", "Ciera Martinez", "Andrew Groover"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017458.t003", "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Genes_up_or_down_regulated_in_PCN_transgenics_involved_in_cell_wall_synthesis_related_processes_/466081", "title"=>"Genes up or down-regulated in PCN transgenics involved in cell wall synthesis related processes.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2011-02-28 01:41:21"}

PMC Usage Stats | Further Information

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  • {"unique-ip"=>"10", "full-text"=>"13", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}

Relative Metric

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