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{"title"=>"Alpha-Linolenic Acid Intake and 10-Year Incidence of Coronary Heart Disease and Stroke in 20,000 Middle-Aged Men and Women in The Netherlands", "type"=>"journal", "authors"=>[{"first_name"=>"Janette", "last_name"=>"de Goede"}, {"first_name"=>"W. M. Monique", "last_name"=>"Verschuren"}, {"first_name"=>"Jolanda M. A.", "last_name"=>"Boer"}, {"first_name"=>"Daan", "last_name"=>"Kromhout"}, {"first_name"=>"Johanna M.", "last_name"=>"Geleijnse"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"21464993", "doi"=>"10.1371/journal.pone.0017967", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "issn"=>"1932-6203"}, "id"=>"953fcbd5-46cc-36c2-9f20-cc8fdb0cd46c", "abstract"=>"Whether intake of alpha-linolenic acid (ALA), the plant-derived n-3 polyunsaturated fatty acid (PUFA), could prevent cardiovascular diseases is not yet clear. We examined the associations of ALA intake with 10-year incidence of coronary heart disease (CHD) and stroke in the Netherlands.", "link"=>"http://www.mendeley.com/research/alphalinolenic-acid-intake-10year-incidence-coronary-heart-disease-stroke-20000-middleaged-men-women-1", "reader_count"=>28, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>1, "Researcher"=>4, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>2, "Other"=>2, "Student > Master"=>2, "Student > Bachelor"=>5, "Lecturer"=>1, "Professor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>1, "Researcher"=>4, "Student > Doctoral Student"=>3, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>2, "Other"=>2, "Student > Master"=>2, "Student > Bachelor"=>5, "Lecturer"=>1, "Professor"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>1, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>2, "Nursing and Health Professions"=>2, "Medicine and Dentistry"=>11, "Agricultural and Biological Sciences"=>5, "Neuroscience"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Chemistry"=>3, "Psychology"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Neuroscience"=>{"Neuroscience"=>1}, "Chemistry"=>{"Chemistry"=>3}, "Psychology"=>{"Psychology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>5}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "reader_count_by_country"=>{"United Kingdom"=>1, "India"=>1}, "group_count"=>0}

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• http://doi.org/10.1017/S0007114516000982
• http://doi.org/10.1177/2047487313517576
• http://doi.org/10.1016/j.atherosclerosis.2011.12.043
• http://doi.org/10.1016/j.biochi.2015.06.005
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• http://doi.org/10.1155/2015/519830
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• http://doi.org/10.1017/jns.2012.18
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• http://doi.org/10.1016/j.maturitas.2012.02.006
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• http://doi.org/10.3945/an.114.005850
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• http://doi.org/10.1155/2020/6676247
• http://doi.org/10.1097/MOL.0b013e3283592eea
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• http://doi.org/10.3945/ajcn.115.127019
• http://doi.org/10.1093/jn/nxy056
• http://doi.org/10.3945/ajcn.112.044040
• http://doi.org/10.1017/S0029665119000582
• http://doi.org/10.3390/nu7053666

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• {"files"=>["https://ndownloader.figshare.com/files/788238"], "description"=>"<p>Footnotes <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017967#pone-0017967-t004\" target=\"_blank\">Table\n 4</a>.</p><p>ALA: alpha-linolenic acid; Q1–Q5: quintiles.</p>1<p>Values are hazard ratios (95% CI), with the first quintile as\n the reference category.</p>2<p>Analyses on ALA from other sources than salad dressings are adjusted\n for ALA in salad dressings in all models.</p>3<p>Model 1: adjusted for age and gender\n (n = 20,069).</p>4<p>Model 2: model 1 with additional adjustments for body mass index,\n total energy intake, cigarette smoking, educational level, parental\n history of myocardial infarction, alcohol intake\n (n = 19,896).</p>5<p>Model 3: model 2 with additional adjustments for intake of vitamin C,\n beta-carotene, fiber, saturated fatty acids, trans fatty acids,\n polyunsaturated fatty acids other than ALA\n (n = 19,896).</p>6<p>Model 4: model 3 with additional adjustment for raw vegetables\n (n = 19,896).</p>", "links"=>[], "tags"=>["chd", "quintiles", "of", "energy-adjusted", "ala", "intake", "sources", "dressings", "in", "dutch", "men"], "article_id"=>458593, "categories"=>["Immunology", "Biochemistry", "Chemistry", "Biotechnology"], "users"=>["Janette de Goede", "W. M. Monique Verschuren", "Jolanda M. A. Boer", "Daan Kromhout", "Johanna M. Geleijnse"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017967.t004", "stats"=>{"downloads"=>2, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Associations_of_incident_CHD_and_stroke_by_quintiles_of____energy_adjusted_ALA_intake_from_other_sources_than_salad_dressings_in____20_069_Dutch_men_and_women_1_/458593", "title"=>"Associations of incident CHD and stroke by quintiles of\n energy-adjusted ALA intake from other sources than salad dressings in\n 20,069 Dutch men and women¹.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 19:37:08"}
• {"files"=>["https://ndownloader.figshare.com/files/788154"], "description"=>"<p>Footnotes <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017967#pone-0017967-t002\" target=\"_blank\">Table\n 2</a>.</p><p>ALA: alpha-linolenic acid; Q1–Q5: quintiles.</p>1<p>Values are hazard ratios (95% CI), with the first quintile as\n the reference category.</p>2<p>Model 1: adjusted for age and gender\n (n = 20,069).</p>3<p>Model 2: model 1 with additional adjustments for body mass index,\n total energy intake, cigarette smoking, educational level, parental\n history of myocardial infarction, alcohol intake\n (n = 19,896).</p>4<p>Model 3: model 2 with additional adjustments for intake of vitamin C,\n beta-carotene, fiber, saturated fatty acids, trans fatty acids,\n polyunsaturated fatty acids other than ALA\n (n = 19,896).</p>", "links"=>[], "tags"=>["coronary", "by", "quintiles", "energy-adjusted", "ala", "intake", "dutch", "men", "and"], "article_id"=>458515, "categories"=>["Immunology", "Biochemistry", "Chemistry", "Biotechnology"], "users"=>["Janette de Goede", "W. M. Monique Verschuren", "Jolanda M. A. Boer", "Daan Kromhout", "Johanna M. Geleijnse"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017967.t002", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Associations_of_incident_coronary_heart_disease_and_stroke_by____quintiles_of_energy_adjusted_ALA_intake_in_20_069_Dutch_men_and____women_1_/458515", "title"=>"Associations of incident coronary heart disease and stroke by\n quintiles of energy-adjusted ALA intake in 20,069 Dutch men and\n women¹.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 19:36:40"}
• {"files"=>["https://ndownloader.figshare.com/files/788099"], "description"=>"<p>Footnotes <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017967#pone-0017967-t001\" target=\"_blank\">Table\n 1</a>.</p><p>ALA: alpha-linolenic acid; Q1–Q5: quintiles; EPA:\n eicosapentaenoic acid; DHA: docosahexaenoic acid.</p>1<p>Values are means ± SD, unless indicated otherwise.</p>2<p>Median with interquartile range.</p>3<p>University or higher vocational training.</p>4<p>Available for participants enrolled between 1994 and 1997\n (n = 15,423).</p>5<p>Nonfasting.</p>", "links"=>[], "tags"=>["characteristics", "dutch", "men", "aged", "quintiles", "energy-adjusted", "ala"], "article_id"=>458463, "categories"=>["Immunology", "Biochemistry", "Chemistry", "Biotechnology"], "users"=>["Janette de Goede", "W. M. Monique Verschuren", "Jolanda M. A. Boer", "Daan Kromhout", "Johanna M. Geleijnse"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017967.t001", "stats"=>{"downloads"=>0, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_characteristics_of_20_069_Dutch_men_and_women_aged____20_65_year_by_quintiles_of_energy_adjusted_ALA_intake_1_/458463", "title"=>"Baseline characteristics of 20,069 Dutch men and women, aged\n 20–65 year, by quintiles of energy-adjusted ALA intake¹.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 19:36:27"}
• {"files"=>["https://ndownloader.figshare.com/files/788191"], "description"=>"<p>Footnotes <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017967#pone-0017967-t003\" target=\"_blank\">Table\n 3</a>.</p><p>ALA: alpha-linolenic acid; Q1–Q5: quintiles.</p>1<p>Values are hazard ratios (95% CI), with the first quintile as\n the reference category.</p>2<p>Analyses on ALA in salad dressings are adjusted for ALA in other\n sources in all models.</p>3<p>Model 1: adjusted for age and gender\n (n = 20,069).</p>4<p>Model 2: model 1 with additional adjustments for body mass index,\n total energy intake, cigarette smoking, educational level, parental\n history of myocardial infarction, alcohol intake\n (n = 19,896).</p>5<p>Model 3: model 2 with additional adjustments for intake of vitamin C,\n beta-carotene, fiber, saturated fatty acids, trans fatty acids,\n polyunsaturated fatty acids other than ALA\n (n = 19,896).</p>6<p>Model 4: model 3 with additional adjustment for raw vegetables\n (n = 19,896).</p>", "links"=>[], "tags"=>["coronary", "by", "quintiles", "energy-adjusted", "ala", "intake", "dressings", "dutch", "men"], "article_id"=>458553, "categories"=>["Immunology", "Biochemistry", "Chemistry", "Biotechnology"], "users"=>["Janette de Goede", "W. M. Monique Verschuren", "Jolanda M. A. Boer", "Daan Kromhout", "Johanna M. Geleijnse"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017967.t003", "stats"=>{"downloads"=>7, "page_views"=>22, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Associations_of_incident_coronary_heart_disease_and_stroke_by____quintiles_of_energy_adjusted_ALA_intake_from_salad_dressings_in_20_069____Dutch_men_and_women_1_/458553", "title"=>"Associations of incident coronary heart disease and stroke by\n quintiles of energy-adjusted ALA intake from salad dressings in 20,069\n Dutch men and women¹.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 19:36:54"}
• {"files"=>["https://ndownloader.figshare.com/files/787970"], "description"=>"<p>¹ Hazard ratios (95% CI) with the first quintile as the\n reference category, adjusted for age, gender, body mass index total\n energy intake, alcohol intake, cigarette smoking, education level,\n parental history of myocardial infarction, intake of vitamin C,\n beta-carotene, fiber, saturated fatty acids, trans fatty acids,\n polyunsaturated fatty acids other than ALA. ² ALA:\n alpha-linolenic acid; Q1–Q5: quintiles.</p>", "links"=>[], "tags"=>["quintiles", "of", "energy-adjusted", "ala", "intake"], "article_id"=>458335, "categories"=>["Immunology", "Biochemistry", "Chemistry", "Biotechnology"], "users"=>["Janette de Goede", "W. M. Monique Verschuren", "Jolanda M. A. Boer", "Daan Kromhout", "Johanna M. Geleijnse"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0017967.g001", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_association_of_incident_total_stroke_by_quintiles_of____energy_adjusted_ALA_intake_1_2_/458335", "title"=>"The association of incident total stroke by quintiles of\n energy-adjusted ALA intake ^1,2.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 19:35:43"}

PMC Usage Stats | Further Information

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• {"unique-ip"=>"13", "full-text"=>"11", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
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• {"unique-ip"=>"18", "full-text"=>"26", "pdf"=>"6", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
• {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
• {"unique-ip"=>"9", "full-text"=>"16", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
• {"unique-ip"=>"9", "full-text"=>"16", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
• {"unique-ip"=>"18", "full-text"=>"23", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
• {"unique-ip"=>"20", "full-text"=>"22", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
• {"unique-ip"=>"16", "full-text"=>"23", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
• {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
• {"unique-ip"=>"14", "full-text"=>"17", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"4"}
• {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"5"}
• {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
• {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
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• {"unique-ip"=>"12", "full-text"=>"15", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
• {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"8"}
• {"unique-ip"=>"22", "full-text"=>"21", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
• {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
• {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
• {"unique-ip"=>"22", "full-text"=>"24", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
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Relative Metric

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F1000Prime