Voltage-Gated Ion Channel Dysfunction Precedes Cardiomyopathy Development in the Dystrophic Heart
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart", "type"=>"journal", "authors"=>[{"first_name"=>"Xaver", "last_name"=>"Koenig", "scopus_author_id"=>"23100266900"}, {"first_name"=>"Sandra", "last_name"=>"Dysek", "scopus_author_id"=>"37115165200"}, {"first_name"=>"Stefanie", "last_name"=>"Kimbacher", "scopus_author_id"=>"26534330700"}, {"first_name"=>"Agnes K.", "last_name"=>"Mike", "scopus_author_id"=>"42361435700"}, {"first_name"=>"Rene", "last_name"=>"Cervenka", "scopus_author_id"=>"24537005800"}, {"first_name"=>"Peter", "last_name"=>"Lukacs", "scopus_author_id"=>"36061004500"}, {"first_name"=>"Katrin", "last_name"=>"Nagl", "scopus_author_id"=>"38061859200"}, {"first_name"=>"Xuan B.", "last_name"=>"Dang", "scopus_author_id"=>"42361009600"}, {"first_name"=>"Hannes", "last_name"=>"Todt", "scopus_author_id"=>"7006485173"}, {"first_name"=>"Reginald E.", "last_name"=>"Bittner", "scopus_author_id"=>"7102510229"}, {"first_name"=>"Karlheinz", "last_name"=>"Hilber", "scopus_author_id"=>"6603551463"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"21677768", "sgr"=>"79956359392", "doi"=>"10.1371/journal.pone.0020300", "scopus"=>"2-s2.0-79956359392", "pui"=>"361809096", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "issn"=>"19326203"}, "id"=>"28a5c822-5759-367b-b73f-1402183fddae", "abstract"=>"Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is associated with severe cardiac complications including cardiomyopathy and cardiac arrhythmias. Recent research suggests that impaired voltage-gated ion channels in dystrophic cardiomyocytes accompany cardiac pathology. It is, however, unknown if the ion channel defects are primary effects of dystrophic gene mutations, or secondary effects of the developing cardiac pathology.", "link"=>"http://www.mendeley.com/research/voltagegated-ion-channel-dysfunction-precedes-cardiomyopathy-development-dystrophic-heart", "reader_count"=>39, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>1, "Student > Doctoral Student"=>2, "Researcher"=>10, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>1, "Student > Master"=>5, "Other"=>4, "Student > Bachelor"=>5, "Professor"=>4}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>1, "Student > Doctoral Student"=>2, "Researcher"=>10, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>1, "Student > Master"=>5, "Other"=>4, "Student > Bachelor"=>5, "Professor"=>4}, "reader_count_by_subject_area"=>{"Biochemistry, Genetics and Molecular Biology"=>7, "Agricultural and Biological Sciences"=>19, "Medicine and Dentistry"=>9, "Neuroscience"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>3}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>9}, "Neuroscience"=>{"Neuroscience"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>19}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>7}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>3}}, "reader_count_by_country"=>{"Austria"=>2, "United States"=>1, "Switzerland"=>2}, "group_count"=>4}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79956359392"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/79956359392?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79956359392&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=79956359392&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/79956359392", "dc:identifier"=>"SCOPUS_ID:79956359392", "eid"=>"2-s2.0-79956359392", "dc:title"=>"Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart", "dc:creator"=>"Koenig X.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"6", "prism:issueIdentifier"=>"5", "prism:pageRange"=>nil, "prism:coverDate"=>"2011-05-27", "prism:coverDisplayDate"=>"2011", "prism:doi"=>"10.1371/journal.pone.0020300", "citedby-count"=>"34", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Medizinische Universitat Wien", "affiliation-city"=>"Vienna", "affiliation-country"=>"Austria"}], "pubmed-id"=>"21677768", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e20300", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0020300", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"5", "year"=>"2011", "pdf_views"=>"12", "xml_views"=>"2", "html_views"=>"73"}
  • {"month"=>"6", "year"=>"2011", "pdf_views"=>"45", "xml_views"=>"0", "html_views"=>"81"}
  • {"month"=>"7", "year"=>"2011", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"48"}
  • {"month"=>"8", "year"=>"2011", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"49"}
  • {"month"=>"9", "year"=>"2011", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"45"}
  • {"month"=>"10", "year"=>"2011", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"11", "year"=>"2011", "pdf_views"=>"19", "xml_views"=>"4", "html_views"=>"30"}
  • {"month"=>"12", "year"=>"2011", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"1", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"33"}
  • {"month"=>"2", "year"=>"2012", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"3", "year"=>"2012", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"27"}
  • {"month"=>"4", "year"=>"2012", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"15"}
  • {"month"=>"5", "year"=>"2012", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"6", "year"=>"2012", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"7", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"8", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"4", "html_views"=>"20"}
  • {"month"=>"9", "year"=>"2012", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"10", "year"=>"2012", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"38"}
  • {"month"=>"11", "year"=>"2012", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"12", "year"=>"2012", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"1", "year"=>"2013", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"41"}
  • {"month"=>"2", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"35"}
  • {"month"=>"3", "year"=>"2013", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"4", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"5", "year"=>"2013", "pdf_views"=>"17", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"6", "year"=>"2013", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"7", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"22"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"35"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"2", "html_views"=>"27"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"71"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"62"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"32"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"59"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"53"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"32"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"3", "html_views"=>"25"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"27"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"12"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"9"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"19"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"28"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"20"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"137"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"3", "html_views"=>"28"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"29"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"26"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"11"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"3", "html_views"=>"11"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"10"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"12"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"7"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"1"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"1"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"21", "xml_views"=>"2", "html_views"=>"7"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"3"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"4"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"11", "xml_views"=>"1", "html_views"=>"8"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"13", "xml_views"=>"1", "html_views"=>"1"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"10", "xml_views"=>"1", "html_views"=>"11"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"4"}
  • {"month"=>"6", "year"=>"2020", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"7", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"8", "year"=>"2020", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"9", "year"=>"2020", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"4"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/772205"], "description"=>"<p><b>A.</b> Original current traces of a typical wt, mdx, and mdx-utr cardiomyocyte, elicited by depolarising voltage-steps. <b>B.</b> Current-voltage relationships derived from a series of experiments as shown in A. The Inset (bar graph) shows a comparison of the maximum current densities between wt and dystrophic cardiomyocytes. <b>C.</b> Comparison of the current decay kinetics between wt and dystrophic cardiomyocytes at different membrane voltages. Decay half-times represent the time periods between the current peak and the time point at which the current had decayed to 50%. * indicates that ANOVA revealed a significant difference (p<0.05) between the respective parameters of the three tested groups. Tukey's Post Hoc test for comparison between two groups revealed significant differences (p<0.05) between mdx-utr and wt, and between mdx-utr and mdx. <b>D.</b> Voltage-dependencies of activation and steady-state inactivation in wt and dystrophic cardiomyocytes. <b>E.</b> Recovery from inactivation in wt and dystrophic cardiomyocytes. Data were fit with a single exponential function. The pulse protocols are shown as insets in the respective graphs. Data points represent means ± SEM. Detailed statistics and n-values are given in <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020300#pone-0020300-t001\" target=\"_blank\">Table 1</a>.</p>", "links"=>[], "tags"=>["properties", "wt", "dystrophic", "neonatal"], "article_id"=>442554, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sodium_channel_properties_in_wt_and_dystrophic_neonatal_cardiomyocytes_/442554", "title"=>"Sodium channel properties in wt and dystrophic neonatal cardiomyocytes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 18:09:40"}
  • {"files"=>["https://ndownloader.figshare.com/files/772376"], "description"=>"<p><b>A.</b> Original barium current traces (five episodes displayed) of a wt and mdx-utr cardiomyocyte, elicited by the pulse protocol on top. The prepulse was used to eliminate currents through T-type calcium channels. <b>B.</b> Current-voltage relationships derived from a series of experiments on wt and dystrophic cardiomyocytes as shown in A. <b>C.</b> Comparison of the current decay kinetics between wt and dystrophic cardiomyocytes at various membrane voltages. τ –values were derived from single exponential fits of the current decay after channel activation. * indicates a significant difference (ANOVA, p<0.05) between the three tested groups. Tukey's Post Hoc test revealed a significant difference (p<0.05) between mdx-utr and wt, but not between mdx-utr and mdx. <b>D.</b> Voltage-dependency of steady-state inactivation in wt and dystrophic cardiomyocytes. For n-values see <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020300#pone-0020300-t001\" target=\"_blank\">Table 1</a>.</p>", "links"=>[], "tags"=>["properties", "wt", "dystrophic", "neonatal"], "article_id"=>442733, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Calcium_channel_properties_in_wt_and_dystrophic_neonatal_cardiomyocytes_/442733", "title"=>"Calcium channel properties in wt and dystrophic neonatal cardiomyocytes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 18:10:38"}
  • {"files"=>["https://ndownloader.figshare.com/files/772603"], "description"=>"<p><b>A.</b> Original current traces of a typical wt, mdx, and mdx-utr cardiomyocyte, elicited by the pulse protocol in B. <b>B.</b> Current-voltage relationships derived from a series of experiments as shown in A. <b>C.</b> Maximum current densities in wt and dystrophic cardiomyocytes. *** indicates that ANOVA revealed a significant difference (p<0.001) between the three tested groups. <b>D.</b> Comparison of the voltage-dependencies of activation and steady-state inactivation between wt and dystrophic cardiomyocytes. For detailed statistics and n-values see <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020300#pone-0020300-t001\" target=\"_blank\">Table 1</a>.</p>", "links"=>[], "tags"=>["properties", "wt", "dystrophic"], "article_id"=>442961, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.g003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sodium_channel_properties_in_wt_and_dystrophic_adult_cardiomyocytes_/442961", "title"=>"Sodium channel properties in wt and dystrophic adult cardiomyocytes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 18:11:51"}
  • {"files"=>["https://ndownloader.figshare.com/files/772776"], "description"=>"<p>Typical AP of a wt cardiomyocyte (top left) elicited by a 4-ms current injection at 125% threshold. On the top right, the upstrokes of typical APs recorded from wt and dystrophic cardiomyocytes are overlayed on an expanded time scale. In the lower panel, maximum upstroke velocity (max. dV/dt), and the maximum depolarisation value reached by the AP (abs. amplitude) are plotted against the membrane potential. * and ** indicate significant differences (ANOVA; p<0.05 and <0.01; n-values: 5–8) between the three tested groups, respectively. Tukey's Post Hoc test revealed no significant differences between mdx-utr and mdx.</p>", "links"=>[], "tags"=>["properties", "wt", "dystrophic"], "article_id"=>443136, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.g004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Action_potential_properties_in_wt_and_dystrophic_adult_cardiomyocytes_/443136", "title"=>"Action potential properties in wt and dystrophic adult cardiomyocytes.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 18:12:52"}
  • {"files"=>["https://ndownloader.figshare.com/files/772940"], "description"=>"<p>(Top) Typical original ECG signals (lead 1) from neonatal and adult wt mice, and the corresponding averages over 100 beats (insets). (Bottom right) Overlay of representative QRS-complexes (lead 2) in adult wt and mdx mice. In the graph, the QRS intervals of neonatal and adult ECGs are compared between wt and dystrophic mice. *** significant difference (ANOVA, p<0.001, n-values: 6–15) between the three tested groups. No significant differences exist between mdx-utr and mdx.</p>", "links"=>[], "tags"=>["ecg", "recordings", "wt", "dystrophic", "neonatal"], "article_id"=>443299, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.g005"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Surface_ECG_recordings_on_wt_and_dystrophic_neonatal_and_adult_mice_/443299", "title"=>"Surface ECG recordings on wt and dystrophic neonatal and adult mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 18:13:49"}
  • {"files"=>["https://ndownloader.figshare.com/files/773026"], "description"=>"<p>The given parameters were obtained by the analysing procedures described in <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020300#s4\" target=\"_blank\">Materials and Methods</a>. V<sub>0.5</sub> is the voltage at which half-maximum activation or inactivation occurred, and k represents the slope factor. V<sub>rev</sub> is the reversal potential, and n gives the number of experiments. Values represent means ± SEM. Data in italic indicate that ANOVA revealed a significant difference (p<0.05) between the respective parameters of the three different groups (wt, mdx, and mdx-utr). Data in bold indicate that ANOVA revealed p<0.01. Statistical comparisons between two groups were made using Tukey's Post Hoc test. Here,</p>&<p>p<0.05 indicates a significant difference between mdx and wt.</p>§<p>p<0.05 and</p>§§§<p>p<0.001 indicate significant differences between mdx-utr and wt.</p>$<p>p<0.05 and</p>$$<p>p<0.01 indicate significant differences between mdx-utr and mdx.</p>", "links"=>[], "tags"=>["barium", "parameters", "wt", "dystrophic"], "article_id"=>443386, "categories"=>["Physiology"], "users"=>["Xaver Koenig", "Sandra Dysek", "Stefanie Kimbacher", "Agnes K. Mike", "Rene Cervenka", "Peter Lukacs", "Katrin Nagl", "Xuan B. Dang", "Hannes Todt", "Reginald E. Bittner", "Karlheinz Hilber"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0020300.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sodium_and_barium_current_parameters_in_wt_and_dystrophic_cardiomyocytes_/443386", "title"=>"Sodium and barium current parameters in wt and dystrophic cardiomyocytes.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 18:14:18"}

PMC Usage Stats | Further Information

  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"46", "year"=>"2011", "pdf"=>"34", "unique-ip"=>"44", "figure"=>"14", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"7", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"38", "unique-ip"=>"42", "pdf"=>"22", "year"=>"2011", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"8", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"28", "year"=>"2011", "pdf"=>"16", "unique-ip"=>"22", "figure"=>"16", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"9", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"43", "unique-ip"=>"34", "pdf"=>"31", "year"=>"2011", "figure"=>"15", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"10", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"54", "year"=>"2011", "pdf"=>"29", "unique-ip"=>"48", "figure"=>"11", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"11", "cited-by"=>"0", "abstract"=>"2", "full-text"=>"55", "unique-ip"=>"51", "pdf"=>"41", "year"=>"2011", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"12", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"23", "year"=>"2011", "pdf"=>"10", "unique-ip"=>"22", "figure"=>"1", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"1", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"20", "unique-ip"=>"24", "pdf"=>"12", "year"=>"2012", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"2", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"34", "year"=>"2012", "pdf"=>"22", "unique-ip"=>"29", "figure"=>"9", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"3", "cited-by"=>"0", "abstract"=>"0", "full-text"=>"40", "unique-ip"=>"29", "pdf"=>"20", "year"=>"2012", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"4", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"16", "year"=>"2012", "pdf"=>"5", "unique-ip"=>"16", "figure"=>"2", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"scanned-page-browse"=>"0", "month"=>"5", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"20", "unique-ip"=>"21", "pdf"=>"13", "year"=>"2012", "figure"=>"8", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"month"=>"6", "scanned-page-browse"=>"0", "cited-by"=>"0", "abstract"=>"1", "full-text"=>"27", "year"=>"2012", "pdf"=>"15", "unique-ip"=>"22", "figure"=>"6", "scanned-summary"=>"0", "supp-data"=>"0"}
  • {"unique-ip"=>"18", "full-text"=>"30", "pdf"=>"22", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"7"}
  • {"unique-ip"=>"9", "full-text"=>"15", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"8"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"5", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"9"}
  • {"unique-ip"=>"20", "full-text"=>"27", "pdf"=>"14", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
  • {"unique-ip"=>"18", "full-text"=>"22", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"20", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2013", "month"=>"2"}
  • {"unique-ip"=>"16", "full-text"=>"12", "pdf"=>"5", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"9", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
  • {"unique-ip"=>"17", "full-text"=>"21", "pdf"=>"12", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
  • {"unique-ip"=>"21", "full-text"=>"21", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
  • {"unique-ip"=>"17", "full-text"=>"21", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
  • {"unique-ip"=>"10", "full-text"=>"16", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"10", "full-text"=>"12", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"9", "full-text"=>"20", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"8", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"13", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"15", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"7", "full-text"=>"10", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"18", "full-text"=>"19", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"17", "full-text"=>"13", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"1", "full-text"=>"0", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"16", "full-text"=>"11", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"15", "full-text"=>"14", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"14", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"10", "full-text"=>"12", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"15", "full-text"=>"16", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"8", "full-text"=>"11", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"13", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"27", "full-text"=>"5", "pdf"=>"26", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"13", "full-text"=>"14", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"12", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"8", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"15", "full-text"=>"15", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"15", "full-text"=>"21", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"5"}
  • {"unique-ip"=>"13", "full-text"=>"11", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"8"}

Relative Metric

{"start_date"=>"2011-01-01T00:00:00Z", "end_date"=>"2011-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences/Anatomy and physiology", "average_usage"=>[298, 559, 690, 805, 916, 1018, 1115, 1201, 1283, 1356, 1425, 1498, 1565, 1635, 1703, 1767, 1835, 1902, 1962, 2027, 2089, 2150, 2210, 2265]}, {"subject_area"=>"/Biology and life sciences/Biochemistry", "average_usage"=>[290, 559, 698, 813, 927, 1028, 1121, 1206, 1289, 1360, 1433, 1501, 1569, 1637, 1707, 1774, 1841, 1911, 1974, 2038, 2103, 2161, 2219, 2280, 2345, 2406, 2466, 2529, 2592, 2654, 2713, 2772, 2835, 2893, 2954, 3020, 3071]}, {"subject_area"=>"/Biology and life sciences/Biophysics", "average_usage"=>[285, 507, 613, 723, 823, 910, 1013, 1086, 1167, 1232, 1293, 1349, 1431, 1486, 1548, 1619, 1669, 1744, 1807, 1866, 1936, 1967, 2032, 2103, 2156, 2213, 2262, 2301, 2334, 2384, 2437, 2482, 2531, 2584, 2637, 2708, 2784]}, {"subject_area"=>"/Medicine and health sciences", "average_usage"=>[303, 571, 709, 823, 937, 1038, 1133, 1216, 1298, 1370, 1447, 1518, 1588, 1656, 1725, 1790, 1856, 1926, 1992, 2054, 2118, 2182, 2242, 2301, 2363, 2425, 2484, 2544, 2602, 2662, 2716, 2776, 2841, 2901, 2960, 3016, 3071]}, {"subject_area"=>"/Medicine and health sciences/Cardiology", "average_usage"=>[265, 555, 659, 780, 896, 1012, 1114, 1201, 1304, 1377, 1446, 1503, 1597, 1664, 1720, 1809, 1870, 1930, 2004, 2070, 2131, 2190, 2241, 2306, 2357, 2409, 2464, 2525, 2573, 2648, 2693, 2771, 2840, 2892, 2968, 3027, 3065]}, {"subject_area"=>"/Medicine and health sciences/Physiology", "average_usage"=>[291, 540, 674, 787, 893, 986, 1087, 1172, 1249, 1319, 1394, 1465, 1526, 1588, 1645, 1713, 1774, 1837, 1903, 1959, 2027, 2085, 2152, 2205, 2259, 2318, 2377, 2436, 2486, 2539, 2603, 2664, 2719, 2779, 2835, 2888, 2944]}, {"subject_area"=>"/People and places", "average_usage"=>[346, 621, 752, 863, 972, 1071, 1187, 1286, 1369, 1443, 1516, 1582, 1659, 1736, 1816, 1899, 1967, 2041, 2119, 2193, 2260, 2330, 2389, 2455, 2510, 2567, 2625, 2698, 2787, 2836, 2908, 2966, 3019, 3080, 3130, 3180, 3244]}, {"subject_area"=>"/People and places/Population groupings", "average_usage"=>[344, 630, 756, 876, 981, 1083, 1179, 1272, 1346, 1421, 1508, 1583, 1659, 1744, 1809, 1891, 1954, 2030, 2105, 2174, 2247, 2324, 2386, 2441, 2502, 2557, 2621, 2685, 2753, 2825, 2882, 2935, 2989, 3052, 3117, 3181, 3242]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[303, 547, 667, 770, 875, 974, 1062, 1140, 1210, 1276, 1344, 1408, 1473, 1534, 1602, 1665, 1732, 1800, 1863, 1920, 1984, 2048, 2099, 2161, 2222, 2285, 2341, 2404, 2473, 2528, 2595, 2650, 2713, 2772, 2835, 2886, 2938]}, {"subject_area"=>"/Physical sciences/Physics", "average_usage"=>[296, 505, 611, 719, 815, 886, 966, 1040, 1111, 1173, 1227, 1283, 1342, 1400, 1459, 1516, 1572, 1635, 1696, 1752, 1804, 1861, 1919, 1976, 2035, 2093, 2142, 2198, 2256, 2309, 2373, 2433, 2486, 2540, 2594, 2652, 2698]}]}
Loading … Spinner
There are currently no alerts