A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum Conditions
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{"title"=>"A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum Conditions", "type"=>"journal", "authors"=>[{"first_name"=>"Meng-Chuan", "last_name"=>"Lai"}, {"first_name"=>"Michael V.", "last_name"=>"Lombardo"}, {"first_name"=>"Greg", "last_name"=>"Pasco"}, {"first_name"=>"Amber N. V.", "last_name"=>"Ruigrok"}, {"first_name"=>"Sally J.", "last_name"=>"Wheelwright"}, {"first_name"=>"Susan A.", "last_name"=>"Sadek"}, {"first_name"=>"Bhismadev", "last_name"=>"Chakrabarti"}, {"first_name"=>"Simon", "last_name"=>"Baron-Cohen"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"1932-6203", "pmid"=>"21695147", "isbn"=>"1932-6203 (Electronic) 1932-6203 (Linking)", "doi"=>"10.1371/journal.pone.0020835"}, "id"=>"22c9fb96-9686-3992-8072-78db8a18be36", "abstract"=>"Autism spectrum conditions (ASC) affect more males than females in the general population. However, within ASC it is unclear if there are phenotypic sex differences. Testing for similarities and differences between the sexes is important not only for clinical assessment but also has implications for theories of typical sex differences and of autism. Using cognitive and behavioral measures, we investigated similarities and differences between the sexes in age- and IQ-matched adults with ASC (high-functioning autism or Asperger syndrome). Of the 83 (45 males and 38 females) participants, 62 (33 males and 29 females) met Autism Diagnostic Interview-Revised (ADI-R) cut-off criteria for autism in childhood and were included in all subsequent analyses. The severity of childhood core autism symptoms did not differ between the sexes. Males and females also did not differ in self-reported empathy, systemizing, anxiety, depression, and obsessive-compulsive traits/symptoms or mentalizing performance. However, adult females with ASC showed more lifetime sensory symptoms (p = 0.036), fewer current socio-communication difficulties (p = 0.001), and more self-reported autistic traits (p = 0.012) than males. In addition, females with ASC who also had developmental language delay had lower current performance IQ than those without developmental language delay (p<0.001), a pattern not seen in males. The absence of typical sex differences in empathizing-systemizing profiles within the autism spectrum confirms a prediction from the extreme male brain theory. Behavioral sex differences within ASC may also reflect different developmental mechanisms between males and females with ASC. We discuss the importance of the superficially better socio-communication ability in adult females with ASC in terms of why females with ASC may more often go under-recognized, and receive their diagnosis later, than males.", "link"=>"http://www.mendeley.com/research/behavioral-comparison-male-female-adults-high-functioning-autism-spectrum-conditions-13", "reader_count"=>329, "reader_count_by_academic_status"=>{"Unspecified"=>6, "Professor > Associate Professor"=>6, "Librarian"=>2, "Student > Doctoral Student"=>28, "Researcher"=>46, "Student > Ph. D. Student"=>64, "Student > Postgraduate"=>16, "Student > Master"=>60, "Other"=>15, "Student > Bachelor"=>66, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>17}, "reader_count_by_user_role"=>{"Unspecified"=>6, "Professor > Associate Professor"=>6, "Librarian"=>2, "Student > Doctoral Student"=>28, "Researcher"=>46, "Student > Ph. D. Student"=>64, "Student > Postgraduate"=>16, "Student > Master"=>60, "Other"=>15, "Student > Bachelor"=>66, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>17}, "reader_count_by_subject_area"=>{"Unspecified"=>15, "Agricultural and Biological Sciences"=>19, "Philosophy"=>2, "Arts and Humanities"=>5, "Business, Management and Accounting"=>3, "Computer Science"=>1, "Decision Sciences"=>1, "Economics, Econometrics and Finance"=>1, "Biochemistry, Genetics and Molecular Biology"=>5, "Nursing and Health Professions"=>1, "Mathematics"=>1, "Medicine and Dentistry"=>43, "Neuroscience"=>16, "Psychology"=>186, "Social Sciences"=>26, "Linguistics"=>4}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>43}, "Social Sciences"=>{"Social Sciences"=>26}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Psychology"=>{"Psychology"=>186}, "Mathematics"=>{"Mathematics"=>1}, "Unspecified"=>{"Unspecified"=>15}, "Arts and Humanities"=>{"Arts and Humanities"=>5}, "Neuroscience"=>{"Neuroscience"=>16}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>19}, "Computer Science"=>{"Computer Science"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>3}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Linguistics"=>{"Linguistics"=>4}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>5}, "Philosophy"=>{"Philosophy"=>2}}, "reader_count_by_country"=>{"Colombia"=>2, "Argentina"=>1, "Turkey"=>1, "United States"=>5, "China"=>1, "Ireland"=>1, "Japan"=>1, "Poland"=>1, "United Kingdom"=>4, "Germany"=>1, "Spain"=>1}, "group_count"=>8}

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Relative Metric

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