Will Adoption of the 2010 WHO ART Guidelines for HIV-Infected TB Patients Increase the Demand for ART Services in India?
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{"title"=>"Will adoption of the 2010 WHO ART guidelines for HIV-infected TB patients increase the demand for ART services in India?", "type"=>"journal", "authors"=>[{"first_name"=>"Ajay M.V.", "last_name"=>"Kumar", "scopus_author_id"=>"35198218300"}, {"first_name"=>"Devesh", "last_name"=>"Gupta", "scopus_author_id"=>"35411756200"}, {"first_name"=>"B. B.", "last_name"=>"Rewari", "scopus_author_id"=>"6506042039"}, {"first_name"=>"Damodar", "last_name"=>"Bachani", "scopus_author_id"=>"6602644743"}, {"first_name"=>"Suresh", "last_name"=>"Mohammed", "scopus_author_id"=>"7102894287"}, {"first_name"=>"Vartika", "last_name"=>"Sharma", "scopus_author_id"=>"36681671600"}, {"first_name"=>"Kumaraswamy", "last_name"=>"Lal", "scopus_author_id"=>"51764159300"}, {"first_name"=>"H. R.Raveendra", "last_name"=>"Reddy", "scopus_author_id"=>"57196621671"}, {"first_name"=>"Balaji", "last_name"=>"Naik", "scopus_author_id"=>"51764224700"}, {"first_name"=>"Rita", "last_name"=>"Prasad", "scopus_author_id"=>"16436846600"}, {"first_name"=>"Mohammed", "last_name"=>"Yaqoob", "scopus_author_id"=>"51764790900"}, {"first_name"=>"K. G.", "last_name"=>"Deepak", "scopus_author_id"=>"51763568100"}, {"first_name"=>"Suresh", "last_name"=>"Shastri", "scopus_author_id"=>"53986532100"}, {"first_name"=>"Srinath", "last_name"=>"Satyanarayana", "scopus_author_id"=>"35732163300"}, {"first_name"=>"Anthony", "last_name"=>"David Harries", "scopus_author_id"=>"51763420200"}, {"first_name"=>"Lakhbir Singh", "last_name"=>"Chauhan", "scopus_author_id"=>"7003509070"}, {"first_name"=>"Puneet", "last_name"=>"Dewan", "scopus_author_id"=>"7101857759"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-80052530721", "pui"=>"362511877", "doi"=>"10.1371/journal.pone.0024297", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "sgr"=>"80052530721", "pmid"=>"21931674"}, "id"=>"5dfe8f17-fbb0-3f2b-98c6-86d0dec5a264", "abstract"=>"BACKGROUND: In 2010, WHO expanded previously-recommended indications for anti-retroviral treatment to include all HIV-infected TB patients irrespective of CD4 count. India, however, still limits ART to those TB patients with CD4 counts <350/mm(3) or with extrapulmonary TB manifestations. We sought to evaluate the additional number of patients that would be initiated on ART if India adopted the current 2010 WHO ART guidelines for HIV-infected TB patients.\\n\\nMETHODS: We evaluated all TB patients recorded in treatment registers of the Revised National TB Control Programme in June 2010 in the high-HIV prevalence state of Karnataka, and cross-matched HIV-infected TB patients with ART programme records.\\n\\nRESULTS: Of 6182 TB patients registered, HIV status was ascertained for 5761(93%) and 710(12%) were HIV-infected. 146(21%) HIV-infected TB patients were on ART prior to TB diagnosis. Of the remaining 564, 497(88%) were assessed for ART eligibility; of these, 436(88%) were eligible for ART according to 2006 WHO ART guidelines. Altogether, 487(69%) HIV-infected TB patients received ART during TB treatment. About 80% started ART within 8 weeks of TB treatment and 95% received an efavirenz based regimen.\\n\\nCONCLUSION: In Karnataka, India, about nine out of ten HIV-infected TB patients were eligible for ART according to 2006 WHO ART guidelines. The efficiency of HIV case finding, ART evaluation, and ART initiation was relatively high, with 78% of eligible HIV-infected patients actually initiated on ART, and 80% within 8 weeks of diagnosis. ART could be extended to all HIV-infected TB patients irrespective of CD4 count with relatively little additional burden on the national ART programme.", "link"=>"http://www.mendeley.com/research/adoption-2010-art-guidelines-hivinfected-tb-patients-increase-demand-art-services-india", "reader_count"=>50, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>21, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>2, "Student > Master"=>7, "Other"=>5, "Student > Bachelor"=>4, "Lecturer"=>2, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>1, "Researcher"=>21, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>2, "Student > Master"=>7, "Other"=>5, "Student > Bachelor"=>4, "Lecturer"=>2, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>3, "Nursing and Health Professions"=>1, "Medicine and Dentistry"=>39, "Agricultural and Biological Sciences"=>2, "Arts and Humanities"=>1, "Business, Management and Accounting"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Social Sciences"=>1, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>39}, "Social Sciences"=>{"Social Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>2}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Unspecified"=>{"Unspecified"=>3}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"United States"=>1, "Brazil"=>1, "Australia"=>1}, "group_count"=>3}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/737907"], "description"=>"<p>*Percentages may not always add up to 100 due to rounding errors.</p><p>**There were 10 patients who had both pulmonary and extrapulmonary TB; they have been classified under extrapulmonary TB as they belong to HIV stage 4 and are ART eligible.</p><p>TB-Tuberculosis; HIV-Human immunodeficiency virus; CNS-Central Nervous System.</p>", "links"=>[], "tags"=>["hiv-infected", "tb", "patients", "registered", "karnataka", "june"], "article_id"=>408256, "categories"=>["Biotechnology", "Science Policy", "Infectious Diseases"], "users"=>["Ajay M. V. Kumar", "Devesh Gupta", "B. B. Rewari", "Damodar Bachani", "Suresh Mohammed", "Vartika Sharma", "Kumaraswamy Lal", "H. R. Raveendra Reddy", "Balaji Naik", "Rita Prasad", "Mohammed Yaqoob", "K. G. Deepak", "Suresh Shastri", "Srinath Satyanarayana", "Anthony David Harries", "Lakhbir Singh Chauhan", "Puneet Dewan"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024297.t001", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_HIV_infected_TB_patients_registered_in_Karnataka_state_India_in_June_2010_/408256", "title"=>"Characteristics of HIV-infected TB patients registered in Karnataka state, India, in June 2010.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 14:59:33"}
  • {"files"=>["https://ndownloader.figshare.com/files/737965"], "description"=>"<p>TB-Tuberculosis; HIV-Human immunodeficiency virus; ART-antiretroviral treatment.</p>", "links"=>[], "tags"=>["initiation", "regimen", "hiv-infected", "tb", "patients", "registered", "karnataka", "june"], "article_id"=>408309, "categories"=>["Biotechnology", "Science Policy", "Infectious Diseases"], "users"=>["Ajay M. V. Kumar", "Devesh Gupta", "B. B. Rewari", "Damodar Bachani", "Suresh Mohammed", "Vartika Sharma", "Kumaraswamy Lal", "H. R. Raveendra Reddy", "Balaji Naik", "Rita Prasad", "Mohammed Yaqoob", "K. G. Deepak", "Suresh Shastri", "Srinath Satyanarayana", "Anthony David Harries", "Lakhbir Singh Chauhan", "Puneet Dewan"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024297.t002", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Timing_of_ART_initiation_and_ART_regimen_in_HIV_infected_TB_patients_registered_in_Karnataka_state_India_in_June_2010_/408309", "title"=>"Timing of ART initiation and ART regimen in HIV-infected TB patients registered in Karnataka state, India, in June 2010.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 14:59:50"}
  • {"files"=>["https://ndownloader.figshare.com/files/737752"], "description"=>"<p>*4 PTB patients were started on ART even though not eligible as per guidelines TB-Tuberculosis; HIV-Human immunodeficiency virus; PTB-pulmonary tuberculosis; EPTB-extrapulmonary tuberculosis; NACO-National AIDS Control Organization; ART-antiretroviral treatment; ARTC-ART centre.</p>", "links"=>[], "tags"=>["initiation", "antiretroviral", "hiv-infected", "tb", "patients", "registered", "karnataka", "june"], "article_id"=>408070, "categories"=>["Biotechnology", "Science Policy", "Infectious Diseases"], "users"=>["Ajay M. V. Kumar", "Devesh Gupta", "B. B. Rewari", "Damodar Bachani", "Suresh Mohammed", "Vartika Sharma", "Kumaraswamy Lal", "H. R. Raveendra Reddy", "Balaji Naik", "Rita Prasad", "Mohammed Yaqoob", "K. G. Deepak", "Suresh Shastri", "Srinath Satyanarayana", "Anthony David Harries", "Lakhbir Singh Chauhan", "Puneet Dewan"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024297.g001", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Eligibility_for_and_initiation_of_antiretroviral_treatment_in_HIV_infected_TB_patients_registered_in_Karnataka_state_India_in_June_2010_/408070", "title"=>"Eligibility for and initiation of antiretroviral treatment in HIV-infected TB patients registered in Karnataka state, India, in June 2010.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 14:58:39"}

PMC Usage Stats | Further Information

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Relative Metric

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