Coverage, Adherence and Costs of Intermittent Preventive Treatment of Malaria in Children Employing Different Delivery Strategies in Jasikan, Ghana
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{"title"=>"Coverage, adherence and costs of intermittent preventive treatment of malaria in children employing different delivery strategies in Jasikan, Ghana", "type"=>"journal", "authors"=>[{"first_name"=>"Edith", "last_name"=>"Patouillard", "scopus_author_id"=>"14621712500"}, {"first_name"=>"Lesong", "last_name"=>"Conteh", "scopus_author_id"=>"6506168921"}, {"first_name"=>"Jayne", "last_name"=>"Webster", "scopus_author_id"=>"7402196821"}, {"first_name"=>"Margaret", "last_name"=>"Kweku", "scopus_author_id"=>"16550392200"}, {"first_name"=>"Daniel", "last_name"=>"Chandramohan", "scopus_author_id"=>"7003426215"}, {"first_name"=>"Brian", "last_name"=>"Greenwood", "scopus_author_id"=>"36040863900"}], "year"=>2011, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"362874028", "sgr"=>"80455158118", "issn"=>"19326203", "pmid"=>"22073137", "scopus"=>"2-s2.0-80455158118", "doi"=>"10.1371/journal.pone.0024871", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)"}, "id"=>"9f48b69d-f922-3e2a-9aa3-45671978818b", "abstract"=>"BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) involves the administration of a course of anti-malarial drugs at specified time intervals to children at risk of malaria regardless of whether or not they are known to be infected. IPTc provides a high level of protection against uncomplicated and severe malaria, with monthly sulphadoxine-pyrimethamine plus amodiaquine (SP&AQ) and sulphadoxine-pyrimethamine plus piperaquine being the most efficacious regimens. A key challenge is the identification of a cost-effective delivery strategy.\\n\\nMETHODS: A community randomized trial was undertaken in Jasikan district, Ghana to assess IPTc effectiveness and costs using SP&AQ delivered in three different ways. Twelve villages were randomly selected to receive IPTc from village health workers (VHWs) or facility-based nurses working at health centres' outpatient departments (OPD) or EPI outreach clinics. Children aged 3 to 59 months-old received one IPT course (three doses) in May, June, September and October. Effectiveness was measured in terms of children covered and adherent to a course and delivery costs were calculated in financial and economic terms using an ingredient approach from the provider perspective.\\n\\nRESULTS: The economic cost per child receiving at least the first dose of all 4 courses was US$4.58 when IPTc was delivered by VHWs, US$4.93 by OPD nurses and US$ 5.65 by EPI nurses. The unit economic cost of receiving all 3 doses of all 4 courses was US$7.56 and US$8.51 when IPTc was delivered by VHWs or facility-based nurses respectively. The main cost driver for the VHW delivery was supervision, reflecting resources used for travelling to more remote communities rather than more intense supervision, and for OPD and EPI delivery, it was the opportunity cost of the time spent by nurses in dispensing IPTc.\\n\\nCONCLUSIONS: VHWs achieve higher IPTc coverage and adherence at lower costs than facility-based nurses in Jasikan district, Ghana.\\n\\nTRIAL REGISTRATION: ClinicalTrials.gov NCT00119132.", "link"=>"http://www.mendeley.com/research/coverage-adherence-costs-intermittent-preventive-treatment-malaria-children-employing-different-deli", "reader_count"=>72, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>2, "Librarian"=>3, "Researcher"=>14, "Student > Doctoral Student"=>2, "Student > Ph. D. 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Student"=>10, "Student > Postgraduate"=>3, "Student > Master"=>16, "Other"=>5, "Student > Bachelor"=>7, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Biochemistry, Genetics and Molecular Biology"=>2, "Nursing and Health Professions"=>5, "Mathematics"=>2, "Medicine and Dentistry"=>27, "Agricultural and Biological Sciences"=>8, "Philosophy"=>1, "Business, Management and Accounting"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>1, "Social Sciences"=>13, "Computer Science"=>2, "Economics, Econometrics and Finance"=>4}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>27}, "Social Sciences"=>{"Social Sciences"=>13}, "Economics, Econometrics and Finance"=>{"Economics, Econometrics and Finance"=>4}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>8}, "Computer Science"=>{"Computer Science"=>2}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>5}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Mathematics"=>{"Mathematics"=>2}, "Unspecified"=>{"Unspecified"=>5}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "Philosophy"=>{"Philosophy"=>1}}, "reader_count_by_country"=>{"Canada"=>1, "Burkina Faso"=>1, "South Africa"=>1, "United Kingdom"=>1, "Spain"=>1}, "group_count"=>9}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/715885"], "description"=>"<p>IPTc economic costs per child receiving the first supervised dose of all four courses by delivery strategy.</p>", "links"=>[], "tags"=>["costs", "receiving", "supervised", "courses"], "article_id"=>386240, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t006", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_economic_costs_per_child_receiving_the_first_supervised_dose_of_all_four_courses_by_delivery_strategy_/386240", "title"=>"IPTc economic costs per child receiving the first supervised dose of all four courses by delivery strategy.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:58:54"}
  • {"files"=>["https://ndownloader.figshare.com/files/716113"], "description"=>"<p>*These figures are slightly different from those published in the effectiveness paper <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0024871#pone.0024871-Kweku1\" target=\"_blank\">[5]</a> following recalculations.</p>", "links"=>[], "tags"=>["outcomes"], "article_id"=>386477, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_coverage_outcomes_by_delivery_strategy_/386477", "title"=>"IPTc coverage outcomes by delivery strategy.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 12:00:06"}
  • {"files"=>["https://ndownloader.figshare.com/files/716040"], "description"=>"<p>*A dose refers to the drugs taken each day of the 3-day IPTc drug regimen; dose 1 given on day 1 was supervised by nurses or VHWs and doses on day 2 and day 3 were the responsibility of parents/care-takers.</p>", "links"=>[], "tags"=>["adherence", "outcomes", "achieved"], "article_id"=>386395, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t002", "stats"=>{"downloads"=>4, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_coverage_and_adherence_outcomes_achieved_for_each_course_by_delivery_strategy_/386395", "title"=>"IPTc coverage and adherence outcomes achieved for each course by delivery strategy.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:59:44"}
  • {"files"=>["https://ndownloader.figshare.com/files/715928"], "description"=>"<p>*VHWs = Village Health Workers; FB = Facility-Based delivery (OPD+EPI nurses).</p>", "links"=>[], "tags"=>["analyses", "iptc", "costs", "adherence", "outcomes", "comparing", "community-", "facility-based"], "article_id"=>386281, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t007", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Sensitivity_analyses_on_IPTc_economic_unit_costs_US_for_different_coverage_and_adherence_outcomes_comparing_community_and_facility_based_delivery_strategies_/386281", "title"=>"Sensitivity analyses on IPTc economic unit costs (US$) for different coverage and adherence outcomes comparing community- and facility-based delivery strategies.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:59:08"}
  • {"files"=>["https://ndownloader.figshare.com/files/716081"], "description"=>"<p>IPTc total financial and economic costs comparing community- and facility-based strategies.</p>", "links"=>[], "tags"=>["costs", "comparing", "community-", "facility-based"], "article_id"=>386435, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t003", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_total_financial_and_economic_costs_comparing_community_and_facility_based_strategies_/386435", "title"=>"IPTc total financial and economic costs comparing community- and facility-based strategies.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:59:55"}
  • {"files"=>["https://ndownloader.figshare.com/files/716004"], "description"=>"<p>n/a = data not available.</p>", "links"=>[], "tags"=>["costs", "measures"], "article_id"=>386365, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t005", "stats"=>{"downloads"=>3, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_unit_economic_costs_for_different_outcome_measures_by_delivery_strategy_/386365", "title"=>"IPTc unit economic costs for different outcome measures by delivery strategy.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:59:33"}
  • {"files"=>["https://ndownloader.figshare.com/files/715972"], "description"=>"<p>IPTc total financial and economic costs comparing OPD and EPI delivery strategies.</p>", "links"=>[], "tags"=>["costs", "comparing", "opd", "epi"], "article_id"=>386328, "categories"=>["Medicine", "Infectious Diseases"], "users"=>["Edith Patouillard", "Lesong Conteh", "Jayne Webster", "Margaret Kweku", "Daniel Chandramohan", "Brian Greenwood"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0024871.t004", "stats"=>{"downloads"=>1, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_IPTc_total_financial_and_economic_costs_comparing_OPD_and_EPI_delivery_strategies_/386328", "title"=>"IPTc total financial and economic costs comparing OPD and EPI delivery strategies.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 11:59:21"}

PMC Usage Stats | Further Information

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Relative Metric

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