HIV Status Disclosure and Retention in Care in HIV-Infected Adolescents on Antiretroviral Therapy (ART) in West Africa
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{"title"=>"HIV status disclosure and retention in care in HIV-infected adolescents on antiretroviral therapy (ART) in West Africa", "type"=>"journal", "authors"=>[{"first_name"=>"Elise", "last_name"=>"Arrivé", "scopus_author_id"=>"6505805018"}, {"first_name"=>"Fatoumata", "last_name"=>"Dicko", "scopus_author_id"=>"26664607800"}, {"first_name"=>"Hind", "last_name"=>"Amghar", "scopus_author_id"=>"6507736420"}, {"first_name"=>"Addi Edmond", "last_name"=>"Aka", "scopus_author_id"=>"55116812300"}, {"first_name"=>"Hélène", "last_name"=>"Dior", "scopus_author_id"=>"55115752700"}, {"first_name"=>"Belinda", "last_name"=>"Bouah", "scopus_author_id"=>"55115752600"}, {"first_name"=>"Mariam", "last_name"=>"Traoré", "scopus_author_id"=>"55158758900"}, {"first_name"=>"Patricia", "last_name"=>"Ogbo", "scopus_author_id"=>"55115751600"}, {"first_name"=>"Hortense Aka", "last_name"=>"Dago-Akribi", "scopus_author_id"=>"6508280296"}, {"first_name"=>"Tanoh Kassi F.", "last_name"=>"Eboua", "scopus_author_id"=>"55115241800"}, {"first_name"=>"Kouadio", "last_name"=>"Kouakou", "scopus_author_id"=>"6602899922"}, {"first_name"=>"Haby Signate", "last_name"=>"Sy", "scopus_author_id"=>"36928030700"}, {"first_name"=>"Ahmadou", "last_name"=>"Alioum", "scopus_author_id"=>"6603335664"}, {"first_name"=>"François", "last_name"=>"Dabis", "scopus_author_id"=>"7101905261"}, {"first_name"=>"Didier Koumavi", "last_name"=>"Ekouévi", "scopus_author_id"=>"6603898420"}, {"first_name"=>"Valériane", "last_name"=>"Leroy", "scopus_author_id"=>"7005119526"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84858638016", "doi"=>"10.1371/journal.pone.0033690", "sgr"=>"84858638016", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)", "pmid"=>"22457782", "issn"=>"19326203", "pui"=>"364480365"}, "id"=>"8a4eef9e-3113-3415-aa01-9e6dab4e3b80", "abstract"=>"OBJECTIVE: We assessed the effect of HIV status disclosure on retention in care from initiation of antiretroviral therapy (ART) among HIV-infected children aged 10 years or more in Cote d'Ivoire, Mali and Sénégal.\\n\\nMETHODS: Multi-centre cohort study within five paediatric clinics participating in the IeDEA West Africa collaboration. HIV-infected patients were included in this study if they met the following inclusion criteria: aged 10-21 years while on ART; having initiated ART ≥ 200 days before the closure date of the clinic database; followed ≥ 15 days from ART initiation in clinics with ≥ 10 adolescents enrolled. Routine follow-up data were merged with those collected through a standardized ad hoc questionnaire on awareness of HIV status. Probability of retention (no death or loss-to-follow-up) was estimated with Kaplan-Meier method. Cox proportional hazard model with date of ART initiation as origin and a delayed entry at date of 10th birthday was used to identify factors associated with death or loss-to-follow-up.\\n\\nRESULTS: 650 adolescents were available for this analysis. Characteristics at ART initiation were: median age of 10.4 years; median CD4 count of 224 cells/mm³ (47% with severe immunosuppression), 48% CDC stage C/WHO stage 3/4. The median follow-up on ART after the age of 10 was 23.3 months; 187 adolescents (28.8%) knew their HIV status. The overall probability of retention at 36 months after ART initiation was 74.6% (95% confidence interval [CI]: 70.5-79.0) and was higher for those disclosed compared to those not: adjusted hazard ratio for the risk of being death or loss-to-follow-up = 0.23 (95% CI: 0.13-0.39).\\n\\nCONCLUSION: About 2/3 of HIV-infected adolescents on ART were not aware of their HIV status in these ART clinics in West Africa but disclosed HIV status improved retention in care. The disclosure process should be thus systematically encouraged and organized in adolescent populations.", "link"=>"http://www.mendeley.com/research/hiv-status-disclosure-retention-care-hivinfected-adolescents-antiretroviral-therapy-art-west-africa-4", "reader_count"=>50, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>3, "Student > Doctoral Student"=>6, "Researcher"=>9, "Student > Ph. D. Student"=>2, "Student > Postgraduate"=>2, "Student > Master"=>16, "Other"=>7, "Student > Bachelor"=>2, "Lecturer"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>3, "Student > Doctoral Student"=>6, "Researcher"=>9, "Student > Ph. D. Student"=>2, "Student > Postgraduate"=>2, "Student > Master"=>16, "Other"=>7, "Student > Bachelor"=>2, "Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>3, "Nursing and Health Professions"=>4, "Medicine and Dentistry"=>20, "Agricultural and Biological Sciences"=>4, "Business, Management and Accounting"=>2, "Psychology"=>2, "Social Sciences"=>13, "Computer Science"=>1, "Decision Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>20}, "Social Sciences"=>{"Social Sciences"=>13}, "Decision Sciences"=>{"Decision Sciences"=>1}, "Psychology"=>{"Psychology"=>2}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>4}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>4}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>2}, "Unspecified"=>{"Unspecified"=>3}}, "reader_count_by_country"=>{"Mozambique"=>1, "United States"=>1, "India"=>1}, "group_count"=>2}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/664702"], "description"=>"<p>Pediatric IeDEA West Africa (WADA) Collaboration.</p>", "links"=>[], "tags"=>["hiv", "disclosure"], "article_id"=>335154, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Cohort_profile_for_the_adolescent_HIV_disclosure_study_/335154", "title"=>"Cohort profile for the adolescent HIV disclosure study.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 07:28:34"}
  • {"files"=>["https://ndownloader.figshare.com/files/664802"], "description"=>"<p>Pediatric IeDEA West Africa Collaboration. * Estimation at 36 months from ART initiation.</p>", "links"=>[], "tags"=>["retention", "hiv", "antiretroviral", "disclosed", "taking", "delayed", "10", "years"], "article_id"=>335264, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Probability_of_retention_in_HIV_care_while_on_antiretroviral_therapy_ART_according_to_disclosed_HIV_status_taking_into_account_the_delayed_entry_at_age_of_10_years_n_8202_8202_650_/335264", "title"=>"Probability of retention in HIV care while on antiretroviral therapy (ART) according to disclosed HIV status taking into account the delayed entry at age of 10 years (n = 650).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-20 07:29:12"}
  • {"files"=>["https://ndownloader.figshare.com/files/664937"], "description"=>"<p>Pediatric IeDEA West Africa (WADA) Collaboration.</p><p>ART: Antiretroviral treatment; NNRTI: non nucleoside reverse transcriptase inhibitor;</p><p>N: number; Med: median; IQR: Inter Quartile Range; Min: minimum; Max: maximum.</p>", "links"=>[], "tags"=>["adolescents"], "article_id"=>335413, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.t001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_adolescents_at_ART_initiation_/335413", "title"=>"Characteristics of adolescents at ART initiation.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 07:29:56"}
  • {"files"=>["https://ndownloader.figshare.com/files/664993"], "description"=>"<p>Pediatric IeDEA West Africa (WADA) Collaboration.</p><p>N: number.</p>", "links"=>[], "tags"=>["adolescents", "hiv", "disclosure"], "article_id"=>335463, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.t003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_adolescents_at_HIV_disclosure_or_last_contact_/335463", "title"=>"Characteristics of adolescents at HIV disclosure or last contact.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 07:30:12"}
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  • {"files"=>["https://ndownloader.figshare.com/files/665110"], "description"=>"<p>Pediatric IeDEA West Africa Collaboration.</p><p>All analyses used the center as a cluster variable, taking into account the correlation of the observations within a same center.</p><p>HR: Hazard ratio.</p><p>aHR: adjusted hazard ratio.</p><p>MD: missing data.</p><p>ART: Antiretroviral therapy.</p><p>NNRTI: non nucleoside reverse transcriptase inhibitor.</p><p>Severe anemia: haemoglobin≤6.9 g/dL.</p><p>Severe immunosuppression : CD4<200 cells/mm<sup>3</sup>.</p>", "links"=>[], "tags"=>["adjusted", "ratios", "intervals", "loss-to-follow-up", "adolescents", "initiation"], "article_id"=>335576, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.t005"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Crude_and_adjusted_hazard_ratios_HR_with_95_confidence_intervals_CI_of_risk_of_death_or_loss_to_follow_up_of_adolescents_after_ART_initiation_n_8202_8202_650_/335576", "title"=>"Crude and adjusted hazard ratios (HR) with 95% confidence intervals (CI) of risk of death or loss-to-follow-up of adolescents after ART initiation (n = 650).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 07:30:44"}
  • {"files"=>["https://ndownloader.figshare.com/files/665162"], "description"=>"<p>Pediatric IeDEA West Africa (WADA) Collaboration.</p><p>ART: Antiretroviral therapy.</p>*<p>Consisted in other persons of the family (uncle, aunt, grand-mother, grand-father, adoptive father or mother), persons from foster care shelters or NGOs (n = 14), nobody involved because of reading the notice (n = 4).</p>", "links"=>[], "tags"=>["hiv", "disclosure"], "article_id"=>335631, "categories"=>["Medicine", "Infectious Diseases", "Biotechnology"], "users"=>["Elise Arrivé", "Fatoumata Dicko", "Hind Amghar", "Addi Edmond Aka", "Hélène Dior", "Belinda Bouah", "Mariam Traoré", "Patricia Ogbo", "Hortense Aka Dago-Akribi", "Tanoh Kassi F. Eboua", "Kouadio Kouakou", "Haby Signate Sy", "Ahmadou Alioum", "François Dabis", "Didier Koumavi Ekouévi", "Valériane Leroy"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0033690.t004"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_the_process_of_HIV_disclosure_of_adolescents_/335631", "title"=>"Characteristics of the process of HIV disclosure of adolescents.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-20 07:31:02"}

PMC Usage Stats | Further Information

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Relative Metric

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