Tailored vs. Standardized Internet-Based Cognitive Behavior Therapy for Depression and Comorbid Symptoms: A Randomized Controlled Trial
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{"title"=>"Tailored vs. Standardized Internet-Based Cognitive Behavior Therapy for Depression and Comorbid Symptoms: A Randomized Controlled Trial", "type"=>"journal", "authors"=>[{"first_name"=>"Robert", "last_name"=>"Johansson"}, {"first_name"=>"Elin", "last_name"=>"Sjöberg"}, {"first_name"=>"Magnus", "last_name"=>"Sjögren"}, {"first_name"=>"Erik", "last_name"=>"Johnsson"}, {"first_name"=>"Per", "last_name"=>"Carlbring"}, {"first_name"=>"Therese", "last_name"=>"Andersson"}, {"first_name"=>"Andréas", "last_name"=>"Rousseau"}, {"first_name"=>"Gerhard", "last_name"=>"Andersson"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"366364248", "sgr"=>"84864240487", "issn"=>"1932-6203", "arxiv"=>"e36905", "pmid"=>"22615841", "scopus"=>"2-s2.0-84864240487", "doi"=>"10.1371/journal.pone.0036905", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)"}, "id"=>"5fff4658-482c-3beb-8c47-62b4cf16ea63", "abstract"=>"Background and Aims: Major depression can be treated by means of cognitive behavior therapy, delivered via the Internet as guided self-help. Individually tailored guided self-help treatments have shown promising results in the treatment of anxiety disorders. This randomized controlled trial tested the efficacy of an Internet-based individually tailored guided self-help treatment which specifically targeted depression with comorbid symptoms. The treatment was compared both to standardized (non-tailored) Internet-based treatment and to an active control group in the form of a monitored online discussion group. Both guided self-help treatments were based on cognitive behavior therapy and lasted for 10 weeks. The discussion group consisted of weekly discussion themes related to depression and the treatment of depression. Methods: A total of 121 participants with diagnosed major depressive disorder and with a range of comorbid symptoms were randomized to three groups. The tailored treatment consisted of a prescribed set of modules targeting depression as well as comorbid problems. The standardized treatment was a previously tested guided self-help program for depression. Results: From pre-treatment to post-treatment, both treatment groups improved on measures of depression, anxiety and quality of life. The results were maintained at a 6-month follow-up. Subgroup analyses showed that the tailored treatment was more effective than the standardized treatment among participants with higher levels of depression at baseline and more comorbidity, both in terms of reduction of depressive symptoms and on recovery rates. In the subgroup with lower baseline scores of depression, few differences were seen between treatments and the discussion group. Conclusions: This study shows that tailored Internet-based treatment for depression is effective and that addressing comorbidity by tailoring may be one way of making guided self-help treatments more effective than standardized approaches in the treatment of more severe depression.", "link"=>"http://www.mendeley.com/research/tailored-vs-standardized-internetbased-cognitive-behavior-therapy-depression-comorbid-symptoms-rando-3", "reader_count"=>144, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>5, "Librarian"=>1, "Researcher"=>25, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>25, "Student > Postgraduate"=>9, "Other"=>6, "Student > Master"=>35, "Student > Bachelor"=>19, "Lecturer"=>1, "Professor"=>4}, "reader_count_by_user_role"=>{"Unspecified"=>5, "Professor > Associate Professor"=>5, "Librarian"=>1, "Researcher"=>25, "Student > Doctoral Student"=>9, "Student > Ph. D. Student"=>25, "Student > Postgraduate"=>9, "Other"=>6, "Student > Master"=>35, "Student > Bachelor"=>19, "Lecturer"=>1, "Professor"=>4}, "reader_count_by_subject_area"=>{"Unspecified"=>12, "Environmental Science"=>1, "Medicine and Dentistry"=>22, "Agricultural and Biological Sciences"=>4, "Arts and Humanities"=>1, "Psychology"=>99, "Social Sciences"=>3, "Computer Science"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>22}, "Social Sciences"=>{"Social Sciences"=>3}, "Psychology"=>{"Psychology"=>99}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>4}, "Computer Science"=>{"Computer Science"=>2}, "Unspecified"=>{"Unspecified"=>12}, "Environmental Science"=>{"Environmental Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"Canada"=>1, "Sweden"=>1, "Netherlands"=>1, "Argentina"=>1, "Norway"=>1, "United States"=>1, "United Kingdom"=>1}, "group_count"=>27}

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  • {"files"=>["https://ndownloader.figshare.com/files/329432", "https://ndownloader.figshare.com/files/329541"], "description"=>"<div><h3>Background and Aims</h3><p>Major depression can be treated by means of cognitive behavior therapy, delivered via the Internet as guided self-help. Individually tailored guided self-help treatments have shown promising results in the treatment of anxiety disorders. This randomized controlled trial tested the efficacy of an Internet-based individually tailored guided self-help treatment which specifically targeted depression with comorbid symptoms. The treatment was compared both to standardized (non-tailored) Internet-based treatment and to an active control group in the form of a monitored online discussion group. Both guided self-help treatments were based on cognitive behavior therapy and lasted for 10 weeks. The discussion group consisted of weekly discussion themes related to depression and the treatment of depression.</p> <h3>Methods</h3><p>A total of 121 participants with diagnosed major depressive disorder and with a range of comorbid symptoms were randomized to three groups. The tailored treatment consisted of a prescribed set of modules targeting depression as well as comorbid problems. The standardized treatment was a previously tested guided self-help program for depression.</p> <h3>Results</h3><p>From pre-treatment to post-treatment, both treatment groups improved on measures of depression, anxiety and quality of life. The results were maintained at a 6-month follow-up. Subgroup analyses showed that the tailored treatment was more effective than the standardized treatment among participants with higher levels of depression at baseline and more comorbidity, both in terms of reduction of depressive symptoms and on recovery rates. In the subgroup with lower baseline scores of depression, few differences were seen between treatments and the discussion group.</p> <h3>Conclusions</h3><p>This study shows that tailored Internet-based treatment for depression is effective and that addressing comorbidity by tailoring may be one way of making guided self-help treatments more effective than standardized approaches in the treatment of more severe depression.</p> <h3>Trial Registration</h3><p>Clinicaltrials.gov <a href=\"http://clinicaltrials.gov/ct2/show/NCT01181583\">NCT01181583</a></p> </div>", "links"=>[], "tags"=>["tailored", "standardized", "internet-based", "comorbid", "randomized", "controlled"], "article_id"=>125056, "categories"=>["Mental Health"], "users"=>["Robert Johansson", "Elin Sjöberg", "Magnus Sjögren", "Erik Johnsson", "Per Carlbring", "Therese Andersson", "Andréas Rousseau", "Gerhard Andersson"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0036905.s001", "https://dx.doi.org/10.1371/journal.pone.0036905.s002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Tailored_vs_Standardized_Internet_Based_Cognitive_Behavior_Therapy_for_Depression_and_Comorbid_Symptoms_A_Randomized_Controlled_Trial/125056", "title"=>"Tailored vs. Standardized Internet-Based Cognitive Behavior Therapy for Depression and Comorbid Symptoms: A Randomized Controlled Trial", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2012-05-15 01:24:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/638850"], "description"=>"<p>Abbreviations: MADRS-S: Montgomery-Åsberg Depression Rating Scale–Self-rated version; SCID: Structured Clinical Interview for DSM-IV Axis I Disorders.</p>", "links"=>[], "tags"=>["reasons", "dropping"], "article_id"=>309338, "categories"=>["Mental Health"], "users"=>["Robert Johansson", "Elin Sjöberg", "Magnus Sjögren", "Erik Johnsson", "Per Carlbring", "Therese Andersson", "Andréas Rousseau", "Gerhard Andersson"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0036905.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Participant_flow_and_reasons_for_dropping_out_throughout_the_trial_/309338", "title"=>"Participant flow and reasons for dropping out throughout the trial.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2012-05-15 02:35:38"}
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Relative Metric

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