Comparison of the Fecal Microbiota of Healthy Horses and Horses with Colitis by High Throughput Sequencing of the V3-V5 Region of the 16S rRNA Gene
- Publication Date
- July 31, 2012
- Journal
- PLOS ONE
- Authors
- Marcio C. Costa, Luis G. Arroyo, Emma Allen Vercoe, Henry R. Stämpfli, et al
- Volume
- 7
- Issue
- 7
- Pages
- e41484
- DOI
- https://dx.plos.org/10.1371/journal.pone.0041484
- Publisher URL
- http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0041484
- PubMed
- http://www.ncbi.nlm.nih.gov/pubmed/22859989
- PubMed Central
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409227
- Europe PMC
- http://europepmc.org/abstract/MED/22859989
- Web of Science
- 000307045600029
- Scopus
- 84864444221
- Mendeley
- http://www.mendeley.com/research/comparison-fecal-microbiota-healthy-horses-horses-colitis-high-throughput-sequencing-v3v5-region-16s
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CiteULike | Further Information
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Mendeley | Further Information
{"title"=>"Comparison of the fecal microbiota of healthy horses and horses with colitis by high throughput sequencing of the V3-V5 region of the 16s rRNA gene", "type"=>"journal", "authors"=>[{"first_name"=>"Marcio C.", "last_name"=>"Costa", "scopus_author_id"=>"16554419700"}, {"first_name"=>"Luis G.", "last_name"=>"Arroyo", "scopus_author_id"=>"6701602095"}, {"first_name"=>"Emma", "last_name"=>"Allen-Vercoe", "scopus_author_id"=>"6602534706"}, {"first_name"=>"Henry R.", "last_name"=>"Stämpfli", "scopus_author_id"=>"6701808970"}, {"first_name"=>"Peter T.", "last_name"=>"Kim", "scopus_author_id"=>"35072743300"}, {"first_name"=>"Amy", "last_name"=>"Sturgeon", "scopus_author_id"=>"55324539200"}, {"first_name"=>"J. Scott", "last_name"=>"Weese", "scopus_author_id"=>"56702153300"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84864444221", "pui"=>"365351858", "doi"=>"10.1371/journal.pone.0041484", "isbn"=>"10.1371/journal.pone.0041484", "sgr"=>"84864444221", "pmid"=>"22859989"}, "id"=>"e21a46b8-d895-3727-9b7d-58a7bb526152", "abstract"=>"The intestinal tract houses one of the richest and most complex microbial populations on the planet, and plays a critical role in health and a wide range of diseases. Limited studies using new sequencing technologies in horses are available. The objective of this study was to characterize the fecal microbiome of healthy horses and to compare the fecal microbiome of healthy horses to that of horses with undifferentiated colitis. A total of 195,748 sequences obtained from 6 healthy horses and 10 horses affected by undifferentiated colitis were analyzed. Firmicutes predominated (68%) among healthy horses followed by Bacteroidetes (14%) and Proteobacteria (10%). In contrast, Bacteroidetes (40%) was the most abundant phylum among horses with colitis, followed by Firmicutes (30%) and Proteobacteria (18%). Healthy horses had a significantly higher relative abundance of Actinobacteria and Spirochaetes while horses with colitis had significantly more Fusobacteria. Members of the Clostridia class were more abundant in healthy horses. Members of the Lachnospiraceae family were the most frequently shared among healthy individuals. The species richness reported here indicates the complexity of the equine intestinal microbiome. The predominance of Clostridia demonstrates the importance of this group of bacteria in healthy horses. The marked differences in the microbiome between healthy horses and horses with colitis indicate that colitis may be a disease of gut dysbiosis, rather than one that occurs simply through overgrowth of an individual pathogen.", "link"=>"http://www.mendeley.com/research/comparison-fecal-microbiota-healthy-horses-horses-colitis-high-throughput-sequencing-v3v5-region-16s", "reader_count"=>110, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>5, "Librarian"=>1, "Researcher"=>23, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>26, "Student > Postgraduate"=>6, "Other"=>7, "Student > Master"=>16, "Student > Bachelor"=>11, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>4}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>5, "Librarian"=>1, "Researcher"=>23, "Student > Doctoral Student"=>5, "Student > Ph. D. Student"=>26, "Student > Postgraduate"=>6, "Other"=>7, "Student > Master"=>16, "Student > Bachelor"=>11, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>4}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>6, "Materials Science"=>1, "Agricultural and Biological Sciences"=>67, "Medicine and Dentistry"=>9, "Arts and Humanities"=>1, "Veterinary Science and Veterinary Medicine"=>13, "Chemistry"=>4, "Immunology and Microbiology"=>3}, "reader_count_by_subdiscipline"=>{"Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>9}, "Chemistry"=>{"Chemistry"=>4}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>67}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>6}, "Unspecified"=>{"Unspecified"=>5}, "Environmental Science"=>{"Environmental Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>13}}, "reader_count_by_country"=>{"Canada"=>1, "Sweden"=>1, "United States"=>2, "United Kingdom"=>2, "Mexico"=>1}, "group_count"=>2}CrossRef
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- {"month"=>"11", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"216"}
- {"month"=>"12", "year"=>"2017", "pdf_views"=>"24", "xml_views"=>"1", "html_views"=>"119"}
- {"month"=>"1", "year"=>"2018", "pdf_views"=>"36", "xml_views"=>"1", "html_views"=>"93"}
- {"month"=>"2", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"0", "html_views"=>"85"}
- {"month"=>"3", "year"=>"2018", "pdf_views"=>"40", "xml_views"=>"3", "html_views"=>"117"}
- {"month"=>"4", "year"=>"2018", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"76"}
- {"month"=>"5", "year"=>"2018", "pdf_views"=>"46", "xml_views"=>"0", "html_views"=>"73"}
- {"month"=>"6", "year"=>"2018", "pdf_views"=>"26", "xml_views"=>"1", "html_views"=>"70"}
- {"month"=>"7", "year"=>"2018", "pdf_views"=>"33", "xml_views"=>"3", "html_views"=>"53"}
- {"month"=>"8", "year"=>"2018", "pdf_views"=>"32", "xml_views"=>"1", "html_views"=>"61"}
- {"month"=>"9", "year"=>"2018", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"85"}
- {"month"=>"10", "year"=>"2018", "pdf_views"=>"29", "xml_views"=>"3", "html_views"=>"71"}
- {"month"=>"11", "year"=>"2018", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"85"}
- {"month"=>"12", "year"=>"2018", "pdf_views"=>"31", "xml_views"=>"1", "html_views"=>"65"}
- {"month"=>"1", "year"=>"2019", "pdf_views"=>"28", "xml_views"=>"1", "html_views"=>"71"}
- {"month"=>"2", "year"=>"2019", "pdf_views"=>"28", "xml_views"=>"0", "html_views"=>"58"}
- {"month"=>"3", "year"=>"2019", "pdf_views"=>"31", "xml_views"=>"0", "html_views"=>"85"}
- {"month"=>"4", "year"=>"2019", "pdf_views"=>"30", "xml_views"=>"0", "html_views"=>"72"}
- {"month"=>"5", "year"=>"2019", "pdf_views"=>"40", "xml_views"=>"0", "html_views"=>"59"}
- {"month"=>"6", "year"=>"2019", "pdf_views"=>"39", "xml_views"=>"0", "html_views"=>"48"}
- {"month"=>"7", "year"=>"2019", "pdf_views"=>"35", "xml_views"=>"0", "html_views"=>"29"}
- {"month"=>"8", "year"=>"2019", "pdf_views"=>"23", "xml_views"=>"0", "html_views"=>"35"}
- {"month"=>"9", "year"=>"2019", "pdf_views"=>"27", "xml_views"=>"0", "html_views"=>"25"}
- {"month"=>"10", "year"=>"2019", "pdf_views"=>"21", "xml_views"=>"0", "html_views"=>"46"}
- {"month"=>"11", "year"=>"2019", "pdf_views"=>"29", "xml_views"=>"0", "html_views"=>"62"}
- {"month"=>"12", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"22"}
PMC Usage Stats | Further Information
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- {"unique-ip"=>"46", "full-text"=>"47", "pdf"=>"33", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"10"}
- {"unique-ip"=>"13", "full-text"=>"20", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"12"}
- {"unique-ip"=>"34", "full-text"=>"35", "pdf"=>"16", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"1"}
- {"unique-ip"=>"18", "full-text"=>"16", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"3"}
- {"unique-ip"=>"29", "full-text"=>"30", "pdf"=>"14", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"16", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"2"}
- {"unique-ip"=>"23", "full-text"=>"23", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"4"}
- {"unique-ip"=>"36", "full-text"=>"42", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"19", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2012", "month"=>"11"}
- {"unique-ip"=>"19", "full-text"=>"19", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"5"}
- {"unique-ip"=>"12", "full-text"=>"10", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"6"}
- {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"11", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"7"}
- {"unique-ip"=>"14", "full-text"=>"12", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2013", "month"=>"8"}
- {"unique-ip"=>"18", "full-text"=>"22", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
- {"unique-ip"=>"14", "full-text"=>"17", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
- {"unique-ip"=>"17", "full-text"=>"20", "pdf"=>"9", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
- {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
- {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
- {"unique-ip"=>"22", "full-text"=>"24", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
- {"unique-ip"=>"6", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
- {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
- {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"4"}
- {"unique-ip"=>"25", "full-text"=>"22", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"3", "year"=>"2015", "month"=>"4"}
- {"unique-ip"=>"19", "full-text"=>"21", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
- {"unique-ip"=>"27", "full-text"=>"26", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"3", "year"=>"2015", "month"=>"6"}
- {"unique-ip"=>"18", "full-text"=>"26", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"7"}
- {"unique-ip"=>"18", "full-text"=>"21", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
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- {"unique-ip"=>"20", "full-text"=>"21", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
- {"unique-ip"=>"28", "full-text"=>"29", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"9"}
- {"unique-ip"=>"24", "full-text"=>"31", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2015", "month"=>"10"}
- {"unique-ip"=>"19", "full-text"=>"32", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2014", "month"=>"7"}
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- {"unique-ip"=>"25", "full-text"=>"23", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"9"}
- {"unique-ip"=>"23", "full-text"=>"23", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
- {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"4", "year"=>"2016", "month"=>"2"}
- {"unique-ip"=>"48", "full-text"=>"55", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
- {"unique-ip"=>"17", "full-text"=>"23", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
- {"unique-ip"=>"19", "full-text"=>"26", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
- {"unique-ip"=>"32", "full-text"=>"38", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"16", "year"=>"2015", "month"=>"11"}
- {"unique-ip"=>"28", "full-text"=>"24", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"9", "year"=>"2015", "month"=>"12"}
- {"unique-ip"=>"22", "full-text"=>"19", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"4", "year"=>"2016", "month"=>"1"}
- {"unique-ip"=>"31", "full-text"=>"29", "pdf"=>"15", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"5", "year"=>"2016", "month"=>"3"}
- {"unique-ip"=>"33", "full-text"=>"32", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2016", "month"=>"4"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
- {"unique-ip"=>"16", "full-text"=>"19", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"6"}
- {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
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- {"unique-ip"=>"39", "full-text"=>"47", "pdf"=>"13", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"10"}
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- {"unique-ip"=>"22", "full-text"=>"28", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
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- {"unique-ip"=>"28", "full-text"=>"30", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2017", "month"=>"5"}
- {"unique-ip"=>"31", "full-text"=>"34", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
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- {"unique-ip"=>"40", "full-text"=>"41", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"4", "year"=>"2017", "month"=>"10"}
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- {"unique-ip"=>"26", "full-text"=>"28", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"5", "year"=>"2018", "month"=>"1"}
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Relative Metric
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