In-Car Nocturnal Blue Light Exposure Improves Motorway Driving: A Randomized Controlled Trial
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{"title"=>"In-Car Nocturnal Blue Light Exposure Improves Motorway Driving: A Randomized Controlled Trial", "type"=>"journal", "authors"=>[{"first_name"=>"Jacques", "last_name"=>"Taillard", "scopus_author_id"=>"6701746180"}, {"first_name"=>"Aurore", "last_name"=>"Capelli", "scopus_author_id"=>"22939984800"}, {"first_name"=>"Patricia", "last_name"=>"Sagaspe", "scopus_author_id"=>"6602725662"}, {"first_name"=>"Anna", "last_name"=>"Anund", "scopus_author_id"=>"23491460800"}, {"first_name"=>"Torbjorn", "last_name"=>"Akerstedt", "scopus_author_id"=>"35500389600"}, {"first_name"=>"Pierre", "last_name"=>"Philip", "scopus_author_id"=>"7102577833"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84867689575", "issn"=>"19326203", "pui"=>"365883745", "sgr"=>"84867689575", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "pmid"=>"23094031", "doi"=>"10.1371/journal.pone.0046750"}, "id"=>"2b021568-0cce-3e5e-95e7-d964da5bf8c9", "abstract"=>"UNLABELLED: Prolonged wakefulness greatly decreases nocturnal driving performance. The development of in-car countermeasures is a future challenge to prevent sleep-related accidents. The aim of this study is to determine whether continuous exposure to monochromatic light in the short wavelengths (blue light), placed on the dashboard, improves night-time driving performance. In this randomized, double-blind, placebo-controlled, cross-over study, 48 healthy male participants (aged 20-50 years) drove 400 km (250 miles) on motorway during night-time. They randomly and consecutively received either continuous blue light exposure (GOLite, Philips, 468 nm) during driving or 2*200 mg of caffeine or placebo of caffeine before and during the break. Treatments were separated by at least 1 week. The outcomes were number of inappropriate line crossings (ILC) and mean standard deviation of the lateral position (SDLP). Eight participants (17%) complained about dazzle during blue light exposure and were removed from the analysis. Results from the 40 remaining participants (mean age ± SD: 32.9±11.1) showed that countermeasures reduced the number of inappropriate line crossings (ILC) (F(2,91.11) = 6.64; p<0.05). Indeed, ILC were lower with coffee (12.51 [95% CI, 5.86 to 19.66], p = 0.001) and blue light (14.58 [CI, 8.75 to 22.58], p = 0.003) than with placebo (26.42 [CI, 19.90 to 33.71]). Similar results were found for SDLP. Treatments did not modify the quality, quantity and timing of 3 subsequent nocturnal sleep episodes. Despite a lesser tolerance, a non-inferior efficacy of continuous nocturnal blue light exposure compared with caffeine suggests that this in-car countermeasure, used occasionally, could be used to fight nocturnal sleepiness at the wheel in blue light-tolerant drivers, whatever their age. More studies are needed to determine the reproducibility of data and to verify if it can be generalized to women.\\n\\nTRIAL REGISTRATION: ClinicalTrials.gov NCT01070004.", "link"=>"http://www.mendeley.com/research/incar-nocturnal-blue-light-exposure-improves-motorway-driving-randomized-controlled-trial", "reader_count"=>55, "reader_count_by_academic_status"=>{"Unspecified"=>2, "Professor > Associate Professor"=>4, "Researcher"=>18, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>1, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>3, "Lecturer"=>2, "Professor"=>5}, "reader_count_by_user_role"=>{"Unspecified"=>2, "Professor > Associate Professor"=>4, "Researcher"=>18, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>1, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>3, "Lecturer"=>2, "Professor"=>5}, "reader_count_by_subject_area"=>{"Engineering"=>5, "Unspecified"=>4, "Environmental Science"=>1, "Nursing and Health Professions"=>1, "Agricultural and Biological Sciences"=>8, "Medicine and Dentistry"=>8, "Neuroscience"=>9, "Arts and Humanities"=>1, "Design"=>1, "Business, Management and Accounting"=>1, "Psychology"=>13, "Computer Science"=>3}, "reader_count_by_subdiscipline"=>{"Design"=>{"Design"=>1}, "Engineering"=>{"Engineering"=>5}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>8}, "Neuroscience"=>{"Neuroscience"=>9}, "Psychology"=>{"Psychology"=>13}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>8}, "Computer Science"=>{"Computer Science"=>3}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Unspecified"=>{"Unspecified"=>4}, "Environmental Science"=>{"Environmental Science"=>1}, "Arts and Humanities"=>{"Arts and Humanities"=>1}}, "reader_count_by_country"=>{"Austria"=>1, "United States"=>1, "Luxembourg"=>1, "United Kingdom"=>1, "France"=>4, "Germany"=>1, "India"=>1, "Spain"=>1}, "group_count"=>5}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/296689", "https://ndownloader.figshare.com/files/296789"], "description"=>"<div><p>Prolonged wakefulness greatly decreases nocturnal driving performance. The development of in-car countermeasures is a future challenge to prevent sleep-related accidents. The aim of this study is to determine whether continuous exposure to monochromatic light in the short wavelengths (blue light), placed on the dashboard, improves night-time driving performance. In this randomized, double-blind, placebo-controlled, cross-over study, 48 healthy male participants (aged 20–50 years) drove 400 km (250 miles) on motorway during night-time. They randomly and consecutively received either continuous blue light exposure (GOLite, Philips, 468 nm) during driving or 2*200 mg of caffeine or placebo of caffeine before and during the break. Treatments were separated by at least 1 week. The outcomes were number of inappropriate line crossings (ILC) and mean standard deviation of the lateral position (SDLP). Eight participants (17%) complained about dazzle during blue light exposure and were removed from the analysis. <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046750#s3\">Results</a> from the 40 remaining participants (mean age ± SD: 32.9±11.1) showed that countermeasures reduced the number of inappropriate line crossings (ILC) (F(2,91.11) = 6.64; p&lt;0.05). Indeed, ILC were lower with coffee (12.51 [95% CI, 5.86 to 19.66], p = 0.001) and blue light (14.58 [CI, 8.75 to 22.58], p = 0.003) than with placebo (26.42 [CI, 19.90 to 33.71]). Similar results were found for SDLP. Treatments did not modify the quality, quantity and timing of 3 subsequent nocturnal sleep episodes. Despite a lesser tolerance, a non-inferior efficacy of continuous nocturnal blue light exposure compared with caffeine suggests that this in-car countermeasure, used occasionally, could be used to fight nocturnal sleepiness at the wheel in blue light-tolerant drivers, whatever their age. More studies are needed to determine the reproducibility of data and to verify if it can be generalized to women.</p> <h3>Tria", "links"=>[], "tags"=>["in-car", "nocturnal", "improves", "motorway", "randomized", "controlled"], "article_id"=>118466, "categories"=>["Neuroscience", "Mental Health", "Physics", "Physiology"], "users"=>["Jacques Taillard", "Aurore Capelli", "Patricia Sagaspe", "Anna Anund", "Torbjorn Akerstedt", "Pierre Philip"], "doi"=>[nil, nil], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/In_Car_Nocturnal_Blue_Light_Exposure_Improves_Motorway_Driving_A_Randomized_Controlled_Trial/118466", "title"=>"In-Car Nocturnal Blue Light Exposure Improves Motorway Driving: A Randomized Controlled Trial", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2012-10-19 02:21:06"}
  • {"files"=>["https://ndownloader.figshare.com/files/555410"], "description"=>"<p>Participant flow: The numbers of participants who were randomly assigned, received intended treatment and were analyzed for the primary outcome.</p>", "links"=>[], "tags"=>["numbers", "randomly", "received", "intended"], "article_id"=>225901, "categories"=>["Physiology", "Neuroscience", "Physics", "Mental Health"], "users"=>["Jacques Taillard", "Aurore Capelli", "Patricia Sagaspe", "Anna Anund", "Torbjorn Akerstedt", "Pierre Philip"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0046750.g001"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Participant_flow_The_numbers_of_participants_who_were_randomly_assigned_received_intended_treatment_and_were_analyzed_for_the_primary_outcome_/225901", "title"=>"Participant flow: The numbers of participants who were randomly assigned, received intended treatment and were analyzed for the primary outcome.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2012-10-19 01:38:21"}
  • {"files"=>["https://ndownloader.figshare.com/files/555544"], "description"=>"<p>Protocol Design: sleep-driving period for the three substance conditions (placebo, coffee and blue light).</p>", "links"=>[], "tags"=>["sleep-driving", "conditions"], "article_id"=>226035, "categories"=>["Physiology", "Neuroscience", "Physics", "Mental Health"], "users"=>["Jacques Taillard", "Aurore Capelli", "Patricia Sagaspe", "Anna Anund", "Torbjorn Akerstedt", "Pierre Philip"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0046750.g002"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Protocol_Design_sleep_driving_period_for_the_three_substance_conditions_placebo_coffee_and_blue_light_/226035", "title"=>"Protocol Design: sleep-driving period for the three substance conditions (placebo, coffee and blue light).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2012-10-19 01:40:35"}
  • {"files"=>["https://ndownloader.figshare.com/files/555621"], "description"=>"<p>* P<0.01.</p>", "links"=>[], "tags"=>["cumulative", "inappropriate", "crossings"], "article_id"=>226111, "categories"=>["Physiology", "Neuroscience", "Physics", "Mental Health"], "users"=>["Jacques Taillard", "Aurore Capelli", "Patricia Sagaspe", "Anna Anund", "Torbjorn Akerstedt", "Pierre Philip"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0046750.g003"], "stats"=>{"downloads"=>0, "page_views"=>0, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Driving_Performance_Mean_cumulative_number_of_inappropriate_line_crossings_in_all_substance_conditions_/226111", "title"=>"Driving Performance: Mean cumulative number of inappropriate line crossings in all substance conditions.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2012-10-19 01:41:51"}

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Relative Metric

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