Friends and Symptom Dimensions in Patients with Psychosis: A Pooled Analysis
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{"title"=>"Friends and Symptom Dimensions in Patients with Psychosis: A Pooled Analysis", "type"=>"journal", "authors"=>[{"first_name"=>"Domenico", "last_name"=>"Giacco", "scopus_author_id"=>"36087378900"}, {"first_name"=>"Rose", "last_name"=>"McCabe", "scopus_author_id"=>"35614132800"}, {"first_name"=>"Thomas", "last_name"=>"Kallert", "scopus_author_id"=>"7006444440"}, {"first_name"=>"Lars", "last_name"=>"Hansson", "scopus_author_id"=>"55579798500"}, {"first_name"=>"Andrea", "last_name"=>"Fiorillo", "scopus_author_id"=>"55141656400"}, {"first_name"=>"Stefan", "last_name"=>"Priebe", "scopus_author_id"=>"8115293800"}], "year"=>2012, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84869751758", "pui"=>"366113363", "doi"=>"10.1371/journal.pone.0050119", "sgr"=>"84869751758", "pmid"=>"23185552"}, "id"=>"dd480d6a-67a2-3d16-b6b8-a3c981f57e0a", "abstract"=>"BACKGROUND Having friends is associated with more favourable clinical outcomes and a higher quality of life in mental disorders. Patients with schizophrenia have fewer friends than other mentally ill patients. No large scale studies have evaluated so far what symptom dimensions of schizophrenia are associated with the lack of friendships. METHODS Data from four multi-centre studies on outpatients with schizophrenia and related disorders (ICD F20-29) were included in a pooled analysis (N = 1396). We established whether patients had close friends and contact with friends by using the equivalent items on friendships of the Manchester Short Assessment of Quality of Life or of the Lancashire Quality of Life Profile. Symptoms were measured by the Brief Psychiatric Rating Scale or by the identical items included in the Positive and Negative Syndrome Scale. RESULTS Seven hundred and sixty-nine patients (55.1%) had seen a friend in the previous week and 917 (65.7%) had someone they regarded as a close friend. Low levels of negative symptoms and hostility were significantly associated with having a close friend and contact with a friend. Overall, almost twice as many patients with absent or mild negative symptoms had met a friend in the last week, compared with those with moderate negative symptoms. CONCLUSIONS Higher levels of negative symptoms and hostility are specifically associated with the lack of friendships in patients with psychotic disorders. These findings suggest the importance of developing effective treatments for negative symptoms and hostility in order to improve the probability of patients with schizophrenia to have friends.", "link"=>"http://www.mendeley.com/research/friends-symptom-dimensions-patients-psychosis-pooled-analysis", "reader_count"=>22, "reader_count_by_academic_status"=>{"Researcher"=>4, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>1, "Student > Master"=>5, "Other"=>2, "Student > Bachelor"=>1, "Lecturer > Senior Lecturer"=>1, "Professor"=>1}, "reader_count_by_user_role"=>{"Researcher"=>4, "Student > Ph. D. Student"=>7, "Student > Postgraduate"=>1, "Student > Master"=>5, "Other"=>2, "Student > Bachelor"=>1, "Lecturer > Senior Lecturer"=>1, "Professor"=>1}, "reader_count_by_subject_area"=>{"Nursing and Health Professions"=>1, "Agricultural and Biological Sciences"=>1, "Medicine and Dentistry"=>1, "Psychology"=>17, "Social Sciences"=>2}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>1}, "Social Sciences"=>{"Social Sciences"=>2}, "Psychology"=>{"Psychology"=>17}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}}, "reader_count_by_country"=>{"Germany"=>1}, "group_count"=>0}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/538791"], "description"=>"a<p>Number of patients at each interval of BPRS subscales score.</p>b<p>Number of patients at each interval of BPRS subscales score who reported to have seen a friend in the last week.</p>c<p>Percentage of patients at each interval of BPRS subscales score who reported to have seen a friend in the last week.</p>", "links"=>[], "tags"=>["friends", "patients", "scores", "bprs", "symptoms", "hostility"], "article_id"=>209280, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t006", "stats"=>{"downloads"=>2, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Contacts_with_friends_of_patients_with_different_scores_on_the_BPRS_negative_symptoms_and_hostility_subscales_/209280", "title"=>"Contacts with friends of patients with different scores on the BPRS negative symptoms and hostility subscales.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:34:40"}
  • {"files"=>["https://ndownloader.figshare.com/files/538863"], "description"=>"a<p>CI = Confidence Interval.</p>", "links"=>[], "tags"=>["analyses", "symptoms", "having", "adjusted", "studies", "centres", "1396"], "article_id"=>209347, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t004", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Univariable_mixed_model_analyses_of_association_between_symptoms_and_likelihood_of_having_a_close_friend_as_a_dependent_variable_adjusted_for_studies_and_centres_within_studies_21_centres_4_studies_1396_patients_a_/209347", "title"=>"Univariable mixed model analyses of association between symptoms and likelihood of having a close friend as a dependent variable adjusted for studies and centres within studies (21 centres, 4 studies, 1396 patients)<sup>a</sup>.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:35:47"}
  • {"files"=>["https://ndownloader.figshare.com/files/538754"], "description"=>"1<p>Sample size refers to included patients with an ICD-10 clinical diagnosis of schizophrenia, schizotypal, or delusional disorders, for which BPRS-18 and MANSA/LQOLP items on friendship scores were available.</p>2<p>LQOLP, Lancashire Quality of Life Profile; MANSA, Manchester Short Assessment of Quality of Life.</p>", "links"=>[], "tags"=>["included", "studies"], "article_id"=>209251, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t001", "stats"=>{"downloads"=>0, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Characteristics_of_the_four_included_studies_and_samples_/209251", "title"=>"Characteristics of the four included studies and samples.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:34:11"}
  • {"files"=>["https://ndownloader.figshare.com/files/289379"], "description"=>"<div><h3>Background</h3><p>Having friends is associated with more favourable clinical outcomes and a higher quality of life in mental disorders. Patients with schizophrenia have fewer friends than other mentally ill patients. No large scale studies have evaluated so far what symptom dimensions of schizophrenia are associated with the lack of friendships.</p> <h3>Methods</h3><p>Data from four multi-centre studies on outpatients with schizophrenia and related disorders (ICD F20-29) were included in a pooled analysis (N = 1396). We established whether patients had close friends and contact with friends by using the equivalent items on friendships of the Manchester Short Assessment of Quality of Life or of the Lancashire Quality of Life Profile. Symptoms were measured by the Brief Psychiatric Rating Scale or by the identical items included in the Positive and Negative Syndrome Scale.</p> <h3>Results</h3><p>Seven hundred and sixty-nine patients (55.1%) had seen a friend in the previous week and 917 (65.7%) had someone they regarded as a close friend. Low levels of negative symptoms and hostility were significantly associated with having a close friend and contact with a friend. Overall, almost twice as many patients with absent or mild negative symptoms had met a friend in the last week, compared with those with moderate negative symptoms.</p> <h3>Conclusions</h3><p>Higher levels of negative symptoms and hostility are specifically associated with the lack of friendships in patients with psychotic disorders. These findings suggest the importance of developing effective treatments for negative symptoms and hostility in order to improve the probability of patients with schizophrenia to have friends.</p> </div>", "links"=>[], "tags"=>["friends", "dimensions", "patients", "pooled", "analysis"], "article_id"=>116975, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119", "stats"=>{"downloads"=>3, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Friends_and_Symptom_Dimensions_in_Patients_with_Psychosis_A_Pooled_Analysis__/116975", "title"=>"Friends and Symptom Dimensions in Patients with Psychosis: A Pooled Analysis", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 01:56:15"}
  • {"files"=>["https://ndownloader.figshare.com/files/538903"], "description"=>"a<p>CI = Confidence Interval.</p>", "links"=>[], "tags"=>["symptoms", "having", "adjusted", "studies", "centres", "1396"], "article_id"=>209392, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t005", "stats"=>{"downloads"=>5, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Multivariable_mixed_model_analysis_of_association_between_symptoms_and_likelihood_of_having_a_close_friend_as_a_dependent_variable_adjusted_for_studies_and_centres_within_studies_21_centres_4_studies_1396_patients_/209392", "title"=>"Multivariable mixed model analysis of association between symptoms and likelihood of having a close friend as a dependent variable adjusted for studies and centres within studies (21 centres, 4 studies, 1396 patients).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:36:32"}
  • {"files"=>["https://ndownloader.figshare.com/files/538727"], "description"=>"a<p>CI = Confidence Interval.</p>", "links"=>[], "tags"=>["associations", "symptoms", "having", "seen", "adjusted", "studies", "centres", "1396"], "article_id"=>209212, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t003", "stats"=>{"downloads"=>1, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Multivariable_mixed_model_analysis_of_associations_between_symptoms_and_having_seen_a_friend_in_the_last_week_as_a_dependent_variable_adjusted_for_studies_and_centres_within_studies_21_centres_4_studies_1396_patients_/209212", "title"=>"Multivariable mixed model analysis of associations between symptoms and having seen a friend in the last week as a dependent variable adjusted for studies and centres within studies (21 centres, 4 studies, 1396 patients).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:33:32"}
  • {"files"=>["https://ndownloader.figshare.com/files/538830"], "description"=>"a<p>Number of patients at each interval of BPRS subscales score.</p>b<p>Number of patients at each interval of BPRS subscales score who reported to have a close friend.</p>c<p>Percentage of patients at each interval of BPRS subscales score who reported to have a close friend.</p>", "links"=>[], "tags"=>["patients", "scores", "bprs", "symptoms", "hostility", "subscales"], "article_id"=>209317, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t007", "stats"=>{"downloads"=>0, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Percentage_of_patients_with_different_scores_on_the_BPRS_negative_symptoms_and_hostility_subscales_who_have_a_close_friend_/209317", "title"=>"Percentage of patients with different scores on the BPRS negative symptoms and hostility subscales who have a close friend.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:35:17"}
  • {"files"=>["https://ndownloader.figshare.com/files/538685"], "description"=>"a<p>CI = Confidence Interval.</p>", "links"=>[], "tags"=>["analyses", "associations", "symptoms", "having", "seen", "adjusted", "studies", "centres", "1396"], "article_id"=>209170, "categories"=>["Mathematics", "Mental Health", "Biotechnology"], "users"=>["Domenico Giacco", "Rose McCabe", "Thomas Kallert", "Lars Hansson", "Andrea Fiorillo", "Stefan Priebe"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0050119.t002", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Univariable_mixed_model_analyses_of_associations_between_symptoms_and_having_seen_a_friend_in_the_last_week_as_a_dependent_variable_adjusted_for_studies_and_centres_within_studies_21_centres_4_studies_1396_patients_/209170", "title"=>"Univariable mixed model analyses of associations between symptoms and having seen a friend in the last week as a dependent variable adjusted for studies and centres within studies (21 centres, 4 studies, 1396 patients).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2012-11-21 02:32:50"}

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Relative Metric

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