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{"title"=>"An ACACB Variant Implicated in Diabetic Nephropathy Associates with Body Mass Index and Gene Expression in Obese Subjects", "type"=>"journal", "authors"=>[{"first_name"=>"Lijun", "last_name"=>"Ma", "scopus_author_id"=>"55693524500"}, {"first_name"=>"Mariana", "last_name"=>"Murea", "scopus_author_id"=>"26654986300"}, {"first_name"=>"James A.", "last_name"=>"Snipes", "scopus_author_id"=>"7003308443"}, {"first_name"=>"Alejandra", "last_name"=>"Marinelarena", "scopus_author_id"=>"55887564500"}, {"first_name"=>"Jacqueline", "last_name"=>"Krüger", "scopus_author_id"=>"55989470000"}, {"first_name"=>"Pamela J.", "last_name"=>"Hicks", "scopus_author_id"=>"26030990200"}, {"first_name"=>"Kurt A.", "last_name"=>"Langberg", "scopus_author_id"=>"39261957500"}, {"first_name"=>"Meredith A.", "last_name"=>"Bostrom", "scopus_author_id"=>"7004297298"}, {"first_name"=>"Jessica N.", "last_name"=>"Cooke", "scopus_author_id"=>"55796183300"}, {"first_name"=>"Daisuke", "last_name"=>"Suzuki", "scopus_author_id"=>"7102449036"}, {"first_name"=>"Tetsuya", "last_name"=>"Babazono", "scopus_author_id"=>"6603908952"}, {"first_name"=>"Takashi", "last_name"=>"Uzu", "scopus_author_id"=>"7003787823"}, {"first_name"=>"Sydney C.W.", "last_name"=>"Tang", "scopus_author_id"=>"7403437082"}, {"first_name"=>"Ashis K.", "last_name"=>"Mondal", "scopus_author_id"=>"7101751593"}, {"first_name"=>"Neeraj K.", "last_name"=>"Sharma", "scopus_author_id"=>"57195680117"}, {"first_name"=>"Sayuko", "last_name"=>"Kobes", "scopus_author_id"=>"6603523137"}, {"first_name"=>"Peter A.", "last_name"=>"Antinozzi", "scopus_author_id"=>"6603641406"}, {"first_name"=>"Matthew", "last_name"=>"Davis", "scopus_author_id"=>"24340613000"}, {"first_name"=>"Swapan K.", "last_name"=>"Das", "scopus_author_id"=>"56434873000"}, {"first_name"=>"Neda", "last_name"=>"Rasouli", "scopus_author_id"=>"8370494700"}, {"first_name"=>"Philip A.", "last_name"=>"Kern", "scopus_author_id"=>"7202583151"}, {"first_name"=>"Nathan J.", "last_name"=>"Shores", "scopus_author_id"=>"23493770600"}, {"first_name"=>"Lawrence L.", "last_name"=>"Rudel", "scopus_author_id"=>"7006953217"}, {"first_name"=>"Matthias", "last_name"=>"Blüher", "scopus_author_id"=>"6602576090"}, {"first_name"=>"Michael", "last_name"=>"Stumvoll", "scopus_author_id"=>"56965303600"}, {"first_name"=>"Donald W.", "last_name"=>"Bowden", "scopus_author_id"=>"7101785120"}, {"first_name"=>"Shiro", "last_name"=>"Maeda", "scopus_author_id"=>"7402105006"}, {"first_name"=>"John S.", "last_name"=>"Parks", "scopus_author_id"=>"7202673747"}, {"first_name"=>"Peter", "last_name"=>"Kovacs", "scopus_author_id"=>"55728560000"}, {"first_name"=>"Robert L.", "last_name"=>"Hanson", "scopus_author_id"=>"7401746098"}, {"first_name"=>"Leslie J.", "last_name"=>"Baier", "scopus_author_id"=>"7003942543"}, {"first_name"=>"Steven C.", "last_name"=>"Elbein", "scopus_author_id"=>"7005744272"}, {"first_name"=>"Barry I.", "last_name"=>"Freedman", "scopus_author_id"=>"7102825752"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"84874525798", "doi"=>"10.1371/journal.pone.0056193", "issn"=>"19326203", "pui"=>"368445542", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)", "pmid"=>"23460794", "scopus"=>"2-s2.0-84874525798"}, "id"=>"f4cef5c5-7a7f-3ef9-9811-1babfc89670c", "abstract"=>"Acetyl coenzyme A carboxylase B gene (ACACB) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). ACACB knock-out mice are also protected from obesity. This study assessed relationships between rs2268388, body mass index (BMI) and gene expression in multiple populations, with and without T2DM. Among subjects without T2DM, rs2268388 DN risk allele (T) associated with higher BMI in Pima Indian children (n = 2021; p-additive = 0.029) and African Americans (AAs) (n = 177; p-additive = 0.05), with a trend in European Americans (EAs) (n = 512; p-additive = 0.09), but not Germans (n = 858; p-additive = 0.765). Association with BMI was seen in a meta-analysis including all non-T2DM subjects (n = 3568; p-additive = 0.02). Among subjects with T2DM, rs2268388 was not associated with BMI in Japanese (n = 2912) or EAs (n = 1149); however, the T allele associated with higher BMI in the subset with BMI≥30 kg/m(2) (n = 568 EAs; p-additive = 0.049, n = 196 Japanese; p-additive = 0.049). Association with BMI was strengthened in a T2DM meta-analysis that included an additional 756 AAs (p-additive = 0.080) and 48 Hong Kong Chinese (p-additive = 0.81) with BMI≥30 kg/m(2) (n = 1575; p-additive = 0.0033). The effect of rs2268388 on gene expression revealed that the T risk allele associated with higher ACACB messenger levels in adipose tissue (41 EAs and 20 AAs with BMI>30 kg/m(2); p-additive = 0.018) and ACACB protein levels in the liver tissue (mixed model p-additive = 0.03, in 25 EA bariatric surgery patients with BMI>30 kg/m(2) for 75 exams). The T allele also associated with higher hepatic triglyceride levels. These data support a role for ACACB in obesity and potential roles for altered lipid metabolism in susceptibility to DN.", "link"=>"http://www.mendeley.com/research/acacb-variant-implicated-diabetic-nephropathy-associates-body-mass-index-gene-expression-obese-subje", "reader_count"=>34, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>5, "Librarian"=>3, "Student > Doctoral Student"=>4, "Researcher"=>4, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>8, "Student > Bachelor"=>3, "Professor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>5, "Librarian"=>3, "Student > Doctoral Student"=>4, "Researcher"=>4, "Student > Ph. D. Student"=>4, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>8, "Student > Bachelor"=>3, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>3, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>4, "Nursing and Health Professions"=>3, "Agricultural and Biological Sciences"=>9, "Medicine and Dentistry"=>14}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>14}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>9}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>4}, "Unspecified"=>{"Unspecified"=>3}, "Environmental Science"=>{"Environmental Science"=>1}}, "reader_count_by_country"=>{"United States"=>2, "Brazil"=>1, "South Africa"=>1}, "group_count"=>1}

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• http://doi.org/10.1186/s12864-018-5009-y
• http://doi.org/10.3109/0886022X.2015.1052978
• http://doi.org/10.1371/journal.pgen.1005349
• http://doi.org/10.1681/ASN.2013091017

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• {"files"=>["https://ndownloader.figshare.com/files/1005522"], "description"=>"<p>EA: European American; AA: African American.</p>*<p>The analysis used age & sex standardized z scores (mean: 0.288±1.04). Mean shown is mean of max z-scores converted to BMI units using mean & SD of 12 year-old females.</p>**<p>Age shown is age at max BMI z-score; not necessarily same as age at max BMI.</p>***<p>max BMI from age >15 yrs. N = 637 since 5 kids had no exams after age 15.</p>", "links"=>[], "tags"=>["genetics and genomics", "diabetes and endocrinology", "Nephrology", "physiology"], "article_id"=>666116, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.t001", "stats"=>{"downloads"=>6, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Demographic_data_of_the_study_cohorts_/666116", "title"=>"Demographic data of the study cohorts.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-27 01:41:56"}
• {"files"=>["https://ndownloader.figshare.com/files/971992", "https://ndownloader.figshare.com/files/971993", "https://ndownloader.figshare.com/files/971994", "https://ndownloader.figshare.com/files/971995", "https://ndownloader.figshare.com/files/971997"], "description"=>"<div><p>Acetyl coenzyme A carboxylase B gene (<i>ACACB</i>) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). <i>ACACB</i> knock-out mice are also protected from obesity. This study assessed relationships between rs2268388, body mass index (BMI) and gene expression in multiple populations, with and without T2DM. Among subjects without T2DM, rs2268388 DN risk allele (T) associated with higher BMI in Pima Indian children (n = 2021; p-additive = 0.029) and African Americans (AAs) (n = 177; p-additive = 0.05), with a trend in European Americans (EAs) (n = 512; p-additive = 0.09), but not Germans (n = 858; p-additive = 0.765). Association with BMI was seen in a meta-analysis including all non-T2DM subjects (n = 3568; p-additive = 0.02). Among subjects with T2DM, rs2268388 was not associated with BMI in Japanese (n = 2912) or EAs (n = 1149); however, the T allele associated with higher BMI in the subset with BMI≥30 kg/m² (n = 568 EAs; p-additive = 0.049, n = 196 Japanese; p-additive = 0.049). Association with BMI was strengthened in a T2DM meta-analysis that included an additional 756 AAs (p-additive = 0.080) and 48 Hong Kong Chinese (p-additive = 0.81) with BMI≥30 kg/m² (n = 1575; p-additive = 0.0033). The effect of rs2268388 on gene expression revealed that the T risk allele associated with higher <i>ACACB</i> messenger levels in adipose tissue (41 EAs and 20 AAs with BMI>30 kg/m²; p-additive = 0.018) and ACACB protein levels in the liver tissue (mixed model p-additive = 0.03, in 25 EA bariatric surgery patients with BMI>30 kg/m² for 75 exams). The T allele also associated with higher hepatic triglyceride levels. These data support a role for <i>ACACB</i> in obesity and potential roles for altered lipid metabolism in susceptibility to DN.</p> </div>", "links"=>[], "tags"=>["variant", "implicated", "diabetic", "nephropathy", "associates", "obese", "subjects"], "article_id"=>640784, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0056193.s001", "https://dx.doi.org/10.1371/journal.pone.0056193.s002", "https://dx.doi.org/10.1371/journal.pone.0056193.s003", "https://dx.doi.org/10.1371/journal.pone.0056193.s004", "https://dx.doi.org/10.1371/journal.pone.0056193.s005"], "stats"=>{"downloads"=>0, "page_views"=>31, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/An_ACACB_Variant_Implicated_in_Diabetic_Nephropathy_Associates_with_Body_Mass_Index_and_Gene_Expression_in_Obese_Subjects__/640784", "title"=>"An <em>ACACB</em> Variant Implicated in Diabetic Nephropathy Associates with Body Mass Index and Gene Expression in Obese Subjects", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2013-02-28 09:30:31"}
• {"files"=>["https://ndownloader.figshare.com/files/971972"], "description"=>"<p>Association of rs2268388 with BMI in non-diabetic subjects.</p>", "links"=>[], "tags"=>["rs2268388", "bmi", "non-diabetic"], "article_id"=>640765, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.g001", "stats"=>{"downloads"=>0, "page_views"=>23, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Association_of_rs2268388_with_BMI_in_non_diabetic_subjects_/640765", "title"=>"Association of rs2268388 with BMI in non-diabetic subjects.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-28 09:27:34"}
• {"files"=>["https://ndownloader.figshare.com/files/971987"], "description"=>"<p>Liver cell triglyceride (TG) by rs2268388.</p>", "links"=>[], "tags"=>["triglyceride"], "article_id"=>640779, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.g005", "stats"=>{"downloads"=>0, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Liver_cell_triglyceride_TG_by_rs2268388_/640779", "title"=>"Liver cell triglyceride (TG) by rs2268388.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-28 09:29:44"}
• {"files"=>["https://ndownloader.figshare.com/files/1005476"], "description"=>"<p>model 1: > = 1 nondiabetic exam age <18 and subsequently developed DM; total n = 642; total exam N = 5321;</p><p>P values were adjusted for age, gender, sibship, and repeated exams (matrix: autoregressive; additive genetic model).</p><p>model 2: All individuals- all examinations; total n = 3197; total exam N = 19385;</p><p>P values were adjusted for age, gender, sibship, diabetic status, duration of diabetes, and repeated exams (matrix: autoregressive; additive genetic model).</p><p>T allele is defined as risk allele for higher BMI z-score.</p><p>n_CC, n_CT, n_TT: number of individuals in each genotypic group. N_exams: number of exams.</p>", "links"=>[], "tags"=>["bmi", "full-heritage", "pima", "indian", "longitudinal"], "article_id"=>666067, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.t002", "stats"=>{"downloads"=>2, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Association_of_rs2268388_C_T_with_BMI_in_full_heritage_Pima_Indian_longitudinal_cohort_/666067", "title"=>"Association of rs2268388(C/T) with BMI in full-heritage Pima Indian longitudinal cohort.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-02-27 01:41:07"}
• {"files"=>["https://ndownloader.figshare.com/files/971980"], "description"=>"<p>Liver ACACB expression by rs2268388.</p>", "links"=>[], "tags"=>["acacb"], "article_id"=>640772, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.g004", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Liver_ACACB_expression_by_rs2268388_/640772", "title"=>"Liver ACACB expression by rs2268388.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-28 09:29:00"}
• {"files"=>["https://ndownloader.figshare.com/files/971977"], "description"=>"<p>Adipose ACACB expression by rs2268388.</p>", "links"=>[], "tags"=>["acacb"], "article_id"=>640769, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.g003", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Adipose_ACACB_expression_by_rs2268388_/640769", "title"=>"Adipose ACACB expression by rs2268388.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-28 09:28:21"}
• {"files"=>["https://ndownloader.figshare.com/files/971974"], "description"=>"<p>Association of rs2268388 with BMI in subjects with type 2 diabetes and BMI≥30 kg/m².</p>", "links"=>[], "tags"=>["rs2268388", "bmi", "subjects"], "article_id"=>640767, "categories"=>["Chemistry", "Marine Biology", "Physiology", "Genetics"], "users"=>["Lijun Ma", "Mariana Murea", "James A. Snipes", "Alejandra Marinelarena", "Jacqueline Krüger", "Pamela J. Hicks", "Kurt A. Langberg", "Meredith A. Bostrom", "Jessica N. Cooke", "Daisuke Suzuki", "Tetsuya Babazono", "Takashi Uzu", "Sydney C. W. Tang", "Ashis K. Mondal", "Neeraj K. Sharma", "Sayuko Kobes", "Peter A. Antinozzi", "Matthew Davis", "Swapan K. Das", "Neda Rasouli", "Philip A. Kern", "Nathan J. Shores", "Lawrence L. Rudel", "Matthias Blüher", "Michael Stumvoll", "Donald W. Bowden", "Shiro Maeda", "John S. Parks", "Peter Kovacs", "Robert L. Hanson", "Leslie J. Baier", "Steven C. Elbein", "Barry I. Freedman"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056193.g002", "stats"=>{"downloads"=>0, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Association_of_rs2268388_with_BMI_in_subjects_with_type_2_diabetes_and_BMI_30_kg_m_2_/640767", "title"=>"Association of rs2268388 with BMI in subjects with type 2 diabetes and BMI≥30 kg/m².", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-28 09:28:03"}

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Relative Metric

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F1000Prime