Epidemiology of Cryptococcal Meningitis in the US: 1997–2009
Publication Date
February 15, 2013
Journal
PLOS ONE
Authors
Vasilios Pyrgos, Amy E. Seitz, Claudia A. Steiner, D. Rebecca Prevots, et al
Volume
8
Issue
2
Pages
e56269
DOI
https://dx.plos.org/10.1371/journal.pone.0056269
Publisher URL
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0056269
PubMed
http://www.ncbi.nlm.nih.gov/pubmed/23457543
PubMed Central
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574138
Europe PMC
http://europepmc.org/abstract/MED/23457543
Web of Science
000315603700039
Scopus
84874078108
Mendeley
http://www.mendeley.com/research/epidemiology-cryptococcal-meningitis-19972009
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Mendeley | Further Information

{"title"=>"Epidemiology of Cryptococcal Meningitis in the US: 1997-2009", "type"=>"journal", "authors"=>[{"first_name"=>"Vasilios", "last_name"=>"Pyrgos", "scopus_author_id"=>"23986437800"}, {"first_name"=>"Amy E.", "last_name"=>"Seitz", "scopus_author_id"=>"24475361200"}, {"first_name"=>"Claudia A.", "last_name"=>"Steiner", "scopus_author_id"=>"7102257730"}, {"first_name"=>"D. Rebecca", "last_name"=>"Prevots", "scopus_author_id"=>"6701839646"}, {"first_name"=>"Peter R.", "last_name"=>"Williamson", "scopus_author_id"=>"7203003816"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84874078108", "pui"=>"368367936", "doi"=>"10.1371/journal.pone.0056269", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)", "sgr"=>"84874078108", "pmid"=>"23457543"}, "id"=>"a79787c4-bf20-3542-9abd-8f8ad72b8ae8", "abstract"=>"Cryptococcal meningitis (CM) causes significant morbidity and mortality globally; however, recent national trends have not been described. Incidence and trends for CM-associated hospitalizations in 18 states were estimated using the Agency for Healthcare and Research Quality (AHRQ) State Inpatient Databases (SID) datasets for 1997 through 2009. We identified 30,840 hospitalizations coded for CM, of which 21.6% were among HIV-uninfected patients. CM in-hospital mortality was significant (12.4% for women and 10.8% for men) with a total of 3,440 deaths over the study period. Co-morbidities of CM coded at increased frequency in HIV-uninfected CM hospitalized populations included hydrocephalus and acute/chronic renal failure as well as possible predispositions including transplantation, combined T and B cell defects, Cushing's syndrome, liver disease and hypogammaglobulinemia. Median hospitalization costs were significant for CM and higher for HIV-uninfected patients (16,803.01 vs. 15,708.07; p<0.0001). Cryptococcal meningitis remains a disease with significant morbidity and mortality in the U.S. and the relative burden among persons without HIV infection is increasing.", "link"=>"http://www.mendeley.com/research/epidemiology-cryptococcal-meningitis-19972009", "reader_count"=>64, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>5, "Researcher"=>13, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>5, "Student > Master"=>14, "Other"=>1, "Student > Bachelor"=>8, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>1, "Student > Doctoral Student"=>5, "Researcher"=>13, "Student > Ph. D. Student"=>8, "Student > Postgraduate"=>5, "Student > Master"=>14, "Other"=>1, "Student > Bachelor"=>8, "Lecturer"=>1, "Lecturer > Senior Lecturer"=>2, "Professor"=>3}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Nursing and Health Professions"=>3, "Biochemistry, Genetics and Molecular Biology"=>3, "Medicine and Dentistry"=>32, "Agricultural and Biological Sciences"=>12, "Neuroscience"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>3, "Social Sciences"=>1, "Immunology and Microbiology"=>4}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>32}, "Neuroscience"=>{"Neuroscience"=>1}, "Social Sciences"=>{"Social Sciences"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>4}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>12}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>3}, "Unspecified"=>{"Unspecified"=>5}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>3}}, "reader_count_by_country"=>{"United States"=>1, "Brazil"=>1, "Australia"=>1, "Chile"=>1}, "group_count"=>4}

CrossRef

Scopus | Further Information

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Figshare

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  • {"files"=>["https://ndownloader.figshare.com/files/487879"], "description"=>"<p>A) Hospitalization for CM per million population in HIV-infected and HIV-uninfected patients. B) In hospital mortality per million population in HIV-infected and HIV-uninfected patients.</p>", "links"=>[], "tags"=>["cm"], "article_id"=>158401, "categories"=>["Biotechnology", "Infectious Diseases", "Neuroscience"], "users"=>["Vasilios Pyrgos", "Amy E. Seitz", "Claudia A. Steiner", "D. Rebecca Prevots", "Peter R. Williamson"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0056269.g002", "stats"=>{"downloads"=>1, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Hospitalizations_for_CM_in_the_US_/158401", "title"=>"Hospitalizations for CM in the US.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-02-19 15:17:49"}

PMC Usage Stats | Further Information

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Relative Metric

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