Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens
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{"title"=>"Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens", "type"=>"journal", "authors"=>[{"first_name"=>"Daniel E.", "last_name"=>"Kadouri", "scopus_author_id"=>"8515119100"}, {"first_name"=>"Kevin", "last_name"=>"To", "scopus_author_id"=>"55673517400"}, {"first_name"=>"Robert M Q", "last_name"=>"Shanks", "scopus_author_id"=>"8947576800"}, {"first_name"=>"Yohei", "last_name"=>"Doi", "scopus_author_id"=>"7401662103"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"pui"=>"368847595", "sgr"=>"84877048448", "issn"=>"19326203", "pmid"=>"23650563", "scopus"=>"2-s2.0-84877048448", "doi"=>"10.1371/journal.pone.0063397", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)"}, "id"=>"8f5b0d60-810a-3b9d-9359-1f5686af9a39", "abstract"=>"Multidrug-resistant (MDR) Gram-negative bacteria have emerged as a serious threat to human and animal health. Bdellovibrio spp. and Micavibrio spp. are Gram-negative bacteria that prey on other Gram-negative bacteria. In this study, the ability of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus to prey on MDR Gram-negative clinical strains was examined. Although the potential use of predatory bacteria to attack MDR pathogens has been suggested, the data supporting these claims is lacking. By conducting predation experiments we have established that predatory bacteria have the capacity to attack clinical strains of a variety of ß-lactamase-producing, MDR Gram-negative bacteria. Our observations indicate that predatory bacteria maintained their ability to prey on MDR bacteria regardless of their antimicrobial resistance, hence, might be used as therapeutic agents where other antimicrobial drugs fail.", "link"=>"http://www.mendeley.com/research/predatory-bacteria-potential-ally-against-multidrugresistant-gramnegative-pathogens", "reader_count"=>95, "reader_count_by_academic_status"=>{"Unspecified"=>5, "Professor > Associate Professor"=>1, "Librarian"=>1, "Student > Doctoral Student"=>7, "Researcher"=>9, "Student > Ph. D. Student"=>23, "Student > Postgraduate"=>3, "Student > Master"=>12, "Other"=>4, "Student > Bachelor"=>27, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>5, "Professor > Associate Professor"=>1, "Librarian"=>1, "Student > Doctoral Student"=>7, "Researcher"=>9, "Student > Ph. D. Student"=>23, "Student > Postgraduate"=>3, "Student > Master"=>12, "Other"=>4, "Student > Bachelor"=>27, "Lecturer > Senior Lecturer"=>1, "Professor"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>7, "Agricultural and Biological Sciences"=>43, "Business, Management and Accounting"=>1, "Veterinary Science and Veterinary Medicine"=>1, "Chemical Engineering"=>2, "Computer Science"=>2, "Engineering"=>2, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>14, "Nursing and Health Professions"=>1, "Medicine and Dentistry"=>9, "Design"=>1, "Physics and Astronomy"=>2, "Immunology and Microbiology"=>9}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>9}, "Physics and Astronomy"=>{"Physics and Astronomy"=>2}, "Unspecified"=>{"Unspecified"=>7}, "Environmental Science"=>{"Environmental Science"=>1}, "Chemical Engineering"=>{"Chemical Engineering"=>2}, "Design"=>{"Design"=>1}, "Engineering"=>{"Engineering"=>2}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>9}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>43}, "Computer Science"=>{"Computer Science"=>2}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>14}, "Veterinary Science and Veterinary Medicine"=>{"Veterinary Science and Veterinary Medicine"=>1}}, "reader_count_by_country"=>{"Sweden"=>1}, "group_count"=>7}

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Relative Metric

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