HIV Infection among Young People in Northwest Tanzania: The Role of Biological, Behavioural and Socio-Demographic Risk Factors
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{"title"=>"HIV Infection among Young People in Northwest Tanzania: The Role of Biological, Behavioural and Socio-Demographic Risk Factors", "type"=>"journal", "authors"=>[{"first_name"=>"Francesca", "last_name"=>"Lemme", "scopus_author_id"=>"57196096029"}, {"first_name"=>"Aoife M.", "last_name"=>"Doyle", "scopus_author_id"=>"8895403800"}, {"first_name"=>"John", "last_name"=>"Changalucha", "scopus_author_id"=>"6701736397"}, {"first_name"=>"Aura", "last_name"=>"Andreasen", "scopus_author_id"=>"24342799300"}, {"first_name"=>"Kathy", "last_name"=>"Baisley", "scopus_author_id"=>"6602372286"}, {"first_name"=>"Kaballa", "last_name"=>"Maganja", "scopus_author_id"=>"36190027900"}, {"first_name"=>"Deborah", "last_name"=>"Watson-Jones", "scopus_author_id"=>"55964647500"}, {"first_name"=>"Saidi", "last_name"=>"Kapiga", "scopus_author_id"=>"7003980583"}, {"first_name"=>"Richard J.", "last_name"=>"Hayes", "scopus_author_id"=>"7402082478"}, {"first_name"=>"David A.", "last_name"=>"Ross", "scopus_author_id"=>"7404448936"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"84879257375", "pmid"=>"23805209", "isbn"=>"1932-6203", "pui"=>"369158071", "issn"=>"19326203", "scopus"=>"2-s2.0-84879257375", "doi"=>"10.1371/journal.pone.0066287"}, "id"=>"49f93fea-a53e-39fd-a61e-f370f953a850", "abstract"=>"BACKGROUND: Young people are at high risk of HIV and developing appropriate prevention programmes requires an understanding of the risk factors for HIV in this age group. We investigated factors associated with HIV among participants aged 15-30 years in a 2007-8 cross-sectional survey nested within a community-randomised trial of the MEMA kwa Vijana intervention in 20 rural communities in northwest Tanzania.\\n\\nMETHODS: We analysed data for 7259(53%) males and 6476(47%) females. Using a proximate-determinant conceptual framework and conditional logistic regression, we obtained sex-specific Odds Ratios (ORs) for the association of HIV infection with socio-demographic, knowledge, behavioural and biological factors.\\n\\nRESULTS: HSV-2 infection was strongly associated with HIV infection (females: adjOR 4.4, 95%CI 3.2-6.1; males: adjOR 4.2, 95%CI 2.8-6.2). Several socio-demographic factors (such as age, marital status and mobility), behavioural factors (condom use, number and type of sexual partnerships) and biological factors (blood transfusion, lifetime pregnancies, genital ulcers, Neisseria gonorrhoeae) were also associated with HIV infection. Among females, lifetime sexual partners (linear trend, p<0.001), ≥2 partners in the past year (adjOR 2.0, 95%CI 1.4-2.8), ≥2 new partners in the past year (adjOR 1.9 95%CI 1.2, 3.3) and concurrent partners in the past year (adjOR 1.6 95%CI 1.1, 2.4) were all associated with HIV infection.\\n\\nCONCLUSIONS: Efforts must be intensified to find effective interventions to reduce HSV-2. Effective behavioural interventions focusing on reducing the number of sexual partnerships and risk behaviour within partnerships are also needed. An increase in risky sexual behaviour may occur following marriage dissolution or when a young woman travels outside of her community and interventions addressing the needs of these subgroups of vulnerable women may be important.\\n\\nTRIAL REGISTRATION: ClinicalTrial.gov NCT00248469.", "link"=>"http://www.mendeley.com/research/hiv-infection-among-young-people-northwest-tanzania-role-biological-behavioural-sociodemographic-ris", "reader_count"=>34, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>3, "Student > Doctoral Student"=>4, "Researcher"=>4, "Student > Ph. D. Student"=>6, "Student > Master"=>10, "Other"=>1, "Student > Bachelor"=>5, "Lecturer"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>3, "Student > Doctoral Student"=>4, "Researcher"=>4, "Student > Ph. D. Student"=>6, "Student > Master"=>10, "Other"=>1, "Student > Bachelor"=>5, "Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>2, "Nursing and Health Professions"=>3, "Agricultural and Biological Sciences"=>3, "Medicine and Dentistry"=>15, "Psychology"=>3, "Social Sciences"=>8}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>15}, "Social Sciences"=>{"Social Sciences"=>8}, "Psychology"=>{"Psychology"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>3}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Unspecified"=>{"Unspecified"=>2}}, "reader_count_by_country"=>{"United Kingdom"=>1}, "group_count"=>2}

Scopus | Further Information

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Figshare

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  • {"files"=>["https://ndownloader.figshare.com/files/1096708"], "description"=>"<p>NOTE: OR: odds ratio; CI: confidence interval; p: pvalue from likelihood-ratio test; pt: p value from likelihood-ratio test for linear trend; NA: not applicable.</p>a<p>The category Domestic/Farmer includes females who reported being either housewives or farmers and males who reported being farmers.</p>b<p><i>Adjusted for age, occupation and marital status.</i></p>c<p><i>Adjusted for age, religion, occupation, marital status and length of time slept away past year.</i></p>d<p><i>for males adjusted for age and marital status; for females adjusted for age, religion, marital status and length of time slept away past year.</i></p>", "links"=>[], "tags"=>["epidemiology", "Infectious disease epidemiology", "Infectious diseases", "Sexually transmitted diseases", "aids", "chlamydia", "gonorrhea", "syphilis", "Non-clinical medicine", "Health care policy", "Health risk analysis", "Public health", "Behavioral and social aspects of health", "Sociology", "Sexual and gender issues", "hiv", "ratios", "socio-demographic"], "article_id"=>727988, "categories"=>["Medicine", "Sociology"], "users"=>["Francesca Lemme", "Aoife M. Doyle", "John Changalucha", "Aura Andreasen", "Kathy Baisley", "Kaballa Maganja", "Deborah Watson-Jones", "Saidi Kapiga", "Richard J. Hayes", "David A. Ross"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066287.t001", "stats"=>{"downloads"=>0, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Risk_factors_for_HIV_infection_odds_ratios_ORs_for_selected_socio_demographic_factors_/727988", "title"=>"Risk factors for HIV infection: odds ratios (ORs) for selected socio-demographic factors.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-21 01:54:21"}
  • {"files"=>["https://ndownloader.figshare.com/files/1096706"], "description"=>"<p>NOTE: OR: odds ratio; CI: confidence interval; HSV2: herpes simplex virus 2; p: pvalue from likelihood-ratio test; pt: pvalue from likelihood -ratio test for linear trend; NA: not applicable.</p>a<p><i>Adjusted for age, occupation, marital status, number of lifetime partners, reported genital ulcers during past year, HSV-2 infection, Neisseria gonorrhoea.</i></p>b<p><i>Adjusted for age, religion, occupation, marital status, length of time slept away past year, HIV knowledge, ever used condom, number of lifetime partners, number of lifetime pregnancies, ever had blood transfusion past 5 yrs, reported genital ulcers during past year, HSV2 infection.</i></p>", "links"=>[], "tags"=>["epidemiology", "Infectious disease epidemiology", "Infectious diseases", "Sexually transmitted diseases", "aids", "chlamydia", "gonorrhea", "syphilis", "Non-clinical medicine", "Health care policy", "Health risk analysis", "Public health", "Behavioral and social aspects of health", "Sociology", "Sexual and gender issues", "hiv", "ratios"], "article_id"=>727986, "categories"=>["Medicine", "Sociology"], "users"=>["Francesca Lemme", "Aoife M. Doyle", "John Changalucha", "Aura Andreasen", "Kathy Baisley", "Kaballa Maganja", "Deborah Watson-Jones", "Saidi Kapiga", "Richard J. Hayes", "David A. Ross"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066287.t003", "stats"=>{"downloads"=>0, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Risk_factors_for_HIV_infection_odds_ratios_ORs_for_selected_biological_factors_/727986", "title"=>"Risk factors for HIV infection: odds ratios (ORs) for selected biological factors.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-21 01:54:21"}

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Relative Metric

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