Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T
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{"title"=>"Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T", "type"=>"journal", "authors"=>[{"first_name"=>"Zhentao", "last_name"=>"Zuo", "scopus_author_id"=>"55262527100"}, {"first_name"=>"Rui", "last_name"=>"Wang", "scopus_author_id"=>"55771463000"}, {"first_name"=>"Yan", "last_name"=>"Zhuo", "scopus_author_id"=>"7005221392"}, {"first_name"=>"Rong", "last_name"=>"Xue", "scopus_author_id"=>"55521202900"}, {"first_name"=>"Keith S.", "last_name"=>"St. Lawrence", "scopus_author_id"=>"35974114800"}, {"first_name"=>"Danny J.J.", "last_name"=>"Wang", "scopus_author_id"=>"55574183324"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84879265244", "pui"=>"369158042", "sgr"=>"84879265244", "isbn"=>"1932-6203 (Electronic){$}\\backslash{\\$}r1932-6203 (Linking)", "issn"=>"19326203", "pmid"=>"23818950", "doi"=>"10.1371/journal.pone.0066612"}, "id"=>"d52f634a-36e1-389b-b906-1337e9a31e24", "abstract"=>"Motivations of arterial spin labeling (ASL) at ultrahigh magnetic fields include prolonged blood T1 and greater signal-to-noise ratio (SNR). However, increased B0 and B1 inhomogeneities and increased specific absorption ratio (SAR) challenge practical ASL implementations. In this study, Turbo-FLASH (Fast Low Angle Shot) based pulsed and pseudo-continuous ASL sequences were performed at 7T, by taking advantage of the relatively low SAR and short TE of Turbo-FLASH that minimizes susceptibility artifacts. Consistent with theoretical predictions, the experimental data showed that Turbo-FLASH based ASL yielded approximately 4 times SNR gain at 7T compared to 3T. High quality perfusion images were obtained with an in-plane spatial resolution of 0.85×1.7 mm(2). A further functional MRI study of motor cortex activation precisely located the primary motor cortex to the precentral gyrus, with the same high spatial resolution. Finally, functional connectivity between left and right motor cortices as well as supplemental motor area were demonstrated using resting state perfusion images. Turbo-FLASH based ASL is a promising approach for perfusion imaging at 7T, which could provide novel approaches to high spatiotemporal resolution fMRI and to investigate the functional connectivity of brain networks at ultrahigh field.", "link"=>"http://www.mendeley.com/research/turboflash-based-arterial-spin-labeled-perfusion-mri-7-t", "reader_count"=>36, "reader_count_by_academic_status"=>{"Unspecified"=>3, "Professor > Associate Professor"=>7, "Researcher"=>6, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>5, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>3, "Professor > Associate Professor"=>7, "Researcher"=>6, "Student > Doctoral Student"=>2, "Student > Ph. D. Student"=>10, "Student > Postgraduate"=>1, "Other"=>1, "Student > Master"=>5, "Professor"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>8, "Unspecified"=>6, "Medicine and Dentistry"=>11, "Agricultural and Biological Sciences"=>3, "Neuroscience"=>3, "Physics and Astronomy"=>4, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>8}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Neuroscience"=>{"Neuroscience"=>3}, "Physics and Astronomy"=>{"Physics and Astronomy"=>4}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>3}, "Computer Science"=>{"Computer Science"=>1}, "Unspecified"=>{"Unspecified"=>6}}, "reader_count_by_country"=>{"Netherlands"=>1, "Egypt"=>1}, "group_count"=>2}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1094947"], "description"=>"<p>Average SNR of Turbo-FLASH based pCASL and PASL with different spatial resolutions at 7 T and 3 T.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "neuroscience", "neuroimaging", "fmri", "neurology", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "spatial", "snr"], "article_id"=>726624, "categories"=>["Medicine", "Engineering", "Biological Sciences"], "users"=>["Zhentao Zuo", "Rui Wang", "Yan Zhuo", "Rong Xue", "Keith S. St. Lawrence", "Danny J. J. Wang"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066612.t001", "stats"=>{"downloads"=>1, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_spatial_SNR_at_7_T_and_3_T_/726624", "title"=>"The spatial SNR at 7 T and 3 T.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:50:24"}
  • {"files"=>["https://ndownloader.figshare.com/files/1094948"], "description"=>"<p>Pearson correlation coefficients (<i>r</i>) between left and right motor cortices, and between SMA and bilateral motor cortices at 7 Τ (p<0.001).</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "neuroscience", "neuroimaging", "fmri", "neurology", "radiology", "Diagnostic radiology", "Magnetic resonance imaging"], "article_id"=>726625, "categories"=>["Medicine", "Engineering", "Biological Sciences"], "users"=>["Zhentao Zuo", "Rui Wang", "Yan Zhuo", "Rong Xue", "Keith S. St. Lawrence", "Danny J. J. Wang"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066612.t003", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Correlation_analysis_of_functional_connectivity_/726625", "title"=>"Correlation analysis of functional connectivity.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:50:25"}
  • {"files"=>["https://ndownloader.figshare.com/files/1094949"], "description"=>"<p>Average temporal SNR of Turbo-FLASH based pCASL and PASL with different spatial resolutions at 7 Τ and 3 Τ.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "neuroscience", "neuroimaging", "fmri", "neurology", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "temporal", "snr"], "article_id"=>726626, "categories"=>["Medicine", "Engineering", "Biological Sciences"], "users"=>["Zhentao Zuo", "Rui Wang", "Yan Zhuo", "Rong Xue", "Keith S. St. Lawrence", "Danny J. J. Wang"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066612.t002", "stats"=>{"downloads"=>2, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_temporal_SNR_at_7_932_and_3_932_/726626", "title"=>"The temporal SNR at 7 Τ and 3 Τ.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-06-20 01:50:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/1094938"], "description"=>"<p>(a) Location of tagging and control plane of pCASL, green is the imaging plane and orange is tagging or control plane, (b) Pulse sequence diagram of Turbo-FLASH based pCASL, w is the post-labeling delay, (c) Location of the selective inversion slab or non-selective inversion slab, and the imaging plane, (d) Pulse sequence diagram of Turbo-FLASH based PASL, TI<sub>1</sub> is the tagging duration and TI<sub>2</sub> is the total duration of tagging and post-labeling delay. A series of inferior saturation pulses were applied after TI1 for complete spoil of the residual tagging bolus.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "neuroscience", "neuroimaging", "fmri", "neurology", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "pasl"], "article_id"=>726617, "categories"=>["Medicine", "Engineering", "Biological Sciences"], "users"=>["Zhentao Zuo", "Rui Wang", "Yan Zhuo", "Rong Xue", "Keith S. St. Lawrence", "Danny J. J. Wang"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0066612.g001", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Schemes_of_pulse_sequence_for_PASL_and_pCASL_/726617", "title"=>"Schemes of pulse sequence for PASL and pCASL.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-06-20 01:50:17"}
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Relative Metric

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