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{"title"=>"Caffeine Intake, Short Bouts of Physical Activity, and Energy Expenditure: A Double-Blind Randomized Crossover Trial", "type"=>"journal", "authors"=>[{"first_name"=>"Pedro B.", "last_name"=>"Júdice", "scopus_author_id"=>"55582912800"}, {"first_name"=>"Catarina N.", "last_name"=>"Matias", "scopus_author_id"=>"35792550300"}, {"first_name"=>"Diana A.", "last_name"=>"Santos", "scopus_author_id"=>"55951861100"}, {"first_name"=>"João P.", "last_name"=>"Magalhães", "scopus_author_id"=>"55583228700"}, {"first_name"=>"Marc T.", "last_name"=>"Hamilton", "scopus_author_id"=>"7401924034"}, {"first_name"=>"Luís B.", "last_name"=>"Sardinha", "scopus_author_id"=>"6603814844"}, {"first_name"=>"Analiza M.", "last_name"=>"Silva", "scopus_author_id"=>"7403221842"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"19326203", "scopus"=>"2-s2.0-84880290630", "pui"=>"369345738", "doi"=>"10.1371/journal.pone.0068936", "isbn"=>"1932-6203", "sgr"=>"84880290630", "pmid"=>"23869233"}, "id"=>"68790a6f-a6e0-3539-aacd-0d685ff65e2b", "abstract"=>"UNLABELLED: PA energy expenditure (PAEE) is the most variable component of Total Energy Expenditure (TEE) and largely due to the balance of sedentary time (SedT) and low intensity physical activity (LIPA). There has been an emergence for seeking an understanding of factors which determine variations in SedT, LIPA, and PAEE. Sedentary behavior and physical activity are relatively resistant to change by experimental dietary treatments and significant body weight changes. Although caffeine (Caf) is by far the most heavily used nutritional agent ingested to promote a sense of vigor/alertness, it is still unknown if Caf is effective in increasing PAEE and physical activity. The aim of the study was to test the hypothesis that 2 daily doses of Caf (as a capsule to blind the treatment and divided equally during breakfast and lunch) increase PAEE and TEE, and it would do so through increasing the frequent and brief bouts of physical activity (~1-5 min long) through the day as measured by accelerometry. In 21 low Caf users (<100 mg day(-1)), we used a double-blind crossover trial (ClinicalTrials.govID;NCT01477294) with two conditions (4-day each with a 3-day washout period) randomly ordered as 5 mg kg(-1) day(-1) of Caf and maltodextrin as placebo (Plc). Resting energy expenditure (REE) by indirect calorimetry, total energy expenditure (TEE) from doubly labeled water, PAEE calculated as TEE-(REE+0.1TEE), and accelerometry measurements of both LIPA and MVPA were not different between conditions. However, regardless of caffeine or placebo, there were several significant relationships between brief bouts of LIPA and MVPA with PAEE. In conclusion, this double-blind study found that low and moderate-vigorous activity as well as the total volume of PAEE in free-living conditions is resistant to dietary caffeine intake that was equivalent to 5 cups of espresso or 7 cups of tea. TRIAL REGISTRATION: ClinicalTrials.gov NCT01477294.", "link"=>"http://www.mendeley.com/research/caffeine-intake-short-bouts-physical-activity-energy-expenditure-doubleblind-randomized-crossover-tr-4", "reader_count"=>29, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>1, "Researcher"=>3, "Student > Doctoral Student"=>4, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>1, "Other"=>3, "Student > Master"=>3, "Student > Bachelor"=>6, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>1, "Researcher"=>3, "Student > Doctoral Student"=>4, "Student > Ph. D. Student"=>6, "Student > Postgraduate"=>1, "Other"=>3, "Student > Master"=>3, "Student > Bachelor"=>6, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>5, "Nursing and Health Professions"=>3, "Biochemistry, Genetics and Molecular Biology"=>1, "Medicine and Dentistry"=>7, "Agricultural and Biological Sciences"=>6, "Business, Management and Accounting"=>1, "Sports and Recreations"=>5, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>7}, "Sports and Recreations"=>{"Sports and Recreations"=>5}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>6}, "Computer Science"=>{"Computer Science"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>3}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Unspecified"=>{"Unspecified"=>5}}, "reader_count_by_country"=>{"Austria"=>1, "Turkey"=>1, "Japan"=>1, "United Kingdom"=>1}, "group_count"=>3}

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• http://doi.org/10.1136/bjsports-2014-094524
• http://doi.org/10.3389/fpsyt.2018.00411
• http://doi.org/10.3390/nu11112665
• http://doi.org/10.1016/j.appet.2014.09.006
• http://doi.org/10.1155/2015/715859
• http://doi.org/10.1152/japplphysiol.00570.2014
• http://doi.org/10.1080/09637486.2017.1320537
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• {"id"=>"356888164524232704", "text"=>"Caffeine makes you feel energized, but does it increase physical activity? No, according to a new double-blind study http://t.co/yvdZqF7v7l", "created_at"=>"2013-07-15T21:29:03Z", "user"=>"GVBodenhausen", "user_name"=>"Galen Bodenhausen", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000051057959/9fb08cd01d9adc2cdf9e21e54a0c18c3_normal.jpeg"}
• {"id"=>"357134348232835074", "text"=>"#PLOS daily5: Frequent moderate/low physical activity is good for your #Health. Does #Caffeine help? : http://t.co/sXUYG5Sw68", "created_at"=>"2013-07-16T13:47:18Z", "user"=>"jthias", "user_name"=>"jthias", "user_profile_image"=>"http://a0.twimg.com/profile_images/1490431696/Good_Pic_normal.jpg"}
• {"id"=>"363500648739782657", "text"=>"No beneficial effects of Caffeine Intake on Short Bouts of Physical Activity, and Energy Expenditure http://t.co/nU210oBXl7", "created_at"=>"2013-08-03T03:24:42Z", "user"=>"ProfDocHealth", "user_name"=>"Gary Wittert", "user_profile_image"=>"http://a0.twimg.com/profile_images/378800000043885717/c71ace70b0ba4c8844d88f690563a648_normal.jpeg"}

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Figshare

• {"files"=>["https://ndownloader.figshare.com/files/1118905", "https://ndownloader.figshare.com/files/1118906"], "description"=>"<div><p>PA energy expenditure (PAEE) is the most variable component of Total Energy Expenditure (TEE) and largely due to the balance of sedentary time (SedT) and low intensity physical activity (LIPA). There has been an emergence for seeking an understanding of factors which determine variations in SedT, LIPA, and PAEE. Sedentary behavior and physical activity are relatively resistant to change by experimental dietary treatments and significant body weight changes. Although caffeine (Caf) is by far the most heavily used nutritional agent ingested to promote a sense of vigor/alertness, it is still unknown if Caf is effective in increasing PAEE and physical activity. The aim of the study was to test the hypothesis that 2 daily doses of Caf (as a capsule to blind the treatment and divided equally during breakfast and lunch) increase PAEE and TEE, and it would do so through increasing the frequent and brief bouts of physical activity (~1-5 min long) through the day as measured by accelerometry. In 21 low Caf users (<100 mg day^-1), we used a double-blind crossover trial (ClinicalTrials.govID;NCT01477294) with two conditions (4-day each with a 3-day washout period) randomly ordered as 5 mg kg^-1 day^-1 of Caf and maltodextrin as placebo (Plc). Resting energy expenditure (REE) by indirect calorimetry, total energy expenditure (TEE) from doubly labeled water, PAEE calculated as TEE-(REE+0.1TEE), and accelerometry measurements of both LIPA and MVPA were not different between conditions. However, regardless of caffeine or placebo, there were several significant relationships between brief bouts of LIPA and MVPA with PAEE. In conclusion, this double-blind study found that low and moderate-vigorous activity as well as the total volume of PAEE in free-living conditions is resistant to dietary caffeine intake that was equivalent to 5 cups of espresso or 7 cups of tea.</p> <p>Trial Registration</p><p>ClinicalTrials.gov <a href=\"http://clinicaltrials.gov/ct2/show/NCT01477294\" target=\"_blank\">NCT01477294</a></p> </div>", "links"=>[], "tags"=>["bouts", "double-blind", "randomized", "crossover"], "article_id"=>745429, "categories"=>["Biological Sciences"], "users"=>["Pedro B. Júdice", "Catarina N. Matias", "Diana A. Santos", "João P. Magalhães", "Marc T. Hamilton", "Luís B. Sardinha", "Analiza M. Silva"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0068936.s001", "https://dx.doi.org/10.1371/journal.pone.0068936.s002"], "stats"=>{"downloads"=>2, "page_views"=>16, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Caffeine_Intake_Short_Bouts_of_Physical_Activity_and_Energy_Expenditure_A_Double_Blind_Randomized_Crossover_Trial_/745429", "title"=>"Caffeine Intake, Short Bouts of Physical Activity, and Energy Expenditure: A Double-Blind Randomized Crossover Trial", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2013-07-15 01:35:53"}
• {"files"=>["https://ndownloader.figshare.com/files/1118903"], "description"=>"<p>Association between physical activity energy expenditure (PAEE) from doubly labeled water (DLW) and the frequency of short bouts (1-4 min) performed at a moderate-to-vigorous physical activity intensity, under placebo (panels A) and caffeine (panels B).</p>", "links"=>[], "tags"=>["expenditure", "moderate-to-vigorous"], "article_id"=>745427, "categories"=>["Biological Sciences"], "users"=>["Pedro B. Júdice", "Catarina N. Matias", "Diana A. Santos", "João P. Magalhães", "Marc T. Hamilton", "Luís B. Sardinha", "Analiza M. Silva"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0068936.g003", "stats"=>{"downloads"=>1, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Physical_activity_energy_expenditure_and_frequency_of_moderate_to_vigorous_intensity_short_bouts_under_placebo_A_and_caffeine_B_/745427", "title"=>"Physical activity energy expenditure and frequency of moderate-to-vigorous intensity short bouts, under placebo-(A) and caffeine-(B).", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-07-15 01:35:53"}
• {"files"=>["https://ndownloader.figshare.com/files/1118901"], "description"=>"<p>Screening, enrollment and interventions of the study participants.</p>", "links"=>[], "tags"=>["enrollment", "interventions"], "article_id"=>745425, "categories"=>["Biological Sciences"], "users"=>["Pedro B. Júdice", "Catarina N. Matias", "Diana A. Santos", "João P. Magalhães", "Marc T. Hamilton", "Luís B. Sardinha", "Analiza M. Silva"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0068936.g001", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Screening_enrollment_and_interventions_of_the_study_participants_/745425", "title"=>"Screening, enrollment and interventions of the study participants.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-07-15 01:35:53"}
• {"files"=>["https://ndownloader.figshare.com/files/1118902"], "description"=>"<p>Association between physical activity energy expenditure (PAEE) from doubly labeled water (DLW) and the frequency of short bouts (>4 min) performed at a low intensity physical activity, under placebo and caffeine conditions.</p>", "links"=>[], "tags"=>["expenditure", "bouts"], "article_id"=>745426, "categories"=>["Biological Sciences"], "users"=>["Pedro B. Júdice", "Catarina N. Matias", "Diana A. Santos", "João P. Magalhães", "Marc T. Hamilton", "Luís B. Sardinha", "Analiza M. Silva"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0068936.g002", "stats"=>{"downloads"=>0, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Physical_activity_energy_expenditure_and_frequency_of_low_intensity_short_bouts_gt_4_min_under_both_conditions_/745426", "title"=>"Physical activity energy expenditure and frequency of low intensity short bouts (>4-min), under both conditions.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-07-15 01:35:53"}

PMC Usage Stats | Further Information

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Relative Metric

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F1000Prime