Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study", "type"=>"journal", "authors"=>[{"first_name"=>"Ian W.", "last_name"=>"Rodger", "scopus_author_id"=>"36878229500"}, {"first_name"=>"Dorothy", "last_name"=>"Dilar", "scopus_author_id"=>"55820972700"}, {"first_name"=>"Janet", "last_name"=>"Dwyer", "scopus_author_id"=>"55821754100"}, {"first_name"=>"John", "last_name"=>"Bienenstock", "scopus_author_id"=>"7101716340"}, {"first_name"=>"Andu", "last_name"=>"Coret", "scopus_author_id"=>"55821652600"}, {"first_name"=>"Judith", "last_name"=>"Coret-Simon", "scopus_author_id"=>"12770157400"}, {"first_name"=>"Gary", "last_name"=>"Foster", "scopus_author_id"=>"7403211223"}, {"first_name"=>"Arlene", "last_name"=>"Franchetto", "scopus_author_id"=>"6602210859"}, {"first_name"=>"Slobodan", "last_name"=>"Franic", "scopus_author_id"=>"56439803900"}, {"first_name"=>"Charles H.", "last_name"=>"Goldsmith", "scopus_author_id"=>"24359010500"}, {"first_name"=>"David", "last_name"=>"Koff", "scopus_author_id"=>"12139415900"}, {"first_name"=>"Norman B.", "last_name"=>"Konyer", "scopus_author_id"=>"6506063614"}, {"first_name"=>"Mitchell", "last_name"=>"Levine", "scopus_author_id"=>"35374537800"}, {"first_name"=>"Ellen", "last_name"=>"McDonald", "scopus_author_id"=>"55821366400"}, {"first_name"=>"Michael D.", "last_name"=>"Noseworthy", "scopus_author_id"=>"6701776288"}, {"first_name"=>"John", "last_name"=>"Paulseth", "scopus_author_id"=>"6603282354"}, {"first_name"=>"Luciana", "last_name"=>"Ribeiro", "scopus_author_id"=>"55822001200"}, {"first_name"=>"Mary Jane", "last_name"=>"Sayles", "scopus_author_id"=>"55861403800"}, {"first_name"=>"Lehana", "last_name"=>"Thabane", "scopus_author_id"=>"6603556364"}], "year"=>2013, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84881535186", "sgr"=>"84881535186", "issn"=>"19326203", "doi"=>"10.1371/journal.pone.0072495", "pmid"=>"23967312", "pui"=>"369566639"}, "id"=>"74956ca8-a651-33fc-ab14-e6ed752a52df", "abstract"=>"OBJECTIVE: Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS. Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous insufficiency (CCSVI), has been advanced. The objective of this study was to evaluate the relative prevalence of the venous abnormalities that define CCSVI. METHODS: A case-control study was conducted in which 100 MS patients aged between 18-65 y meeting the revised McDonald criteria were randomly selected and stratified into one of four MS subtypes: relapsing/remitting, secondary progressive, primary progressive and benign. Control subjects (16-70 y) with no known history of MS or other neurological condition were matched with the MS cases. All cases and controls underwent ultrasound imaging of the veins of the neck plus the deep cerebral veins, and magnetic resonance imaging of the neck veins and brain. These procedures were performed on each participant on the same day. RESULTS: On ultrasound we found no evidence of reflux, stenosis or blockage in the internal jugular veins (IJV) or vertebral veins (VV) in any study participant. Similarly, there was no evidence of either reflux or cessation of flow in the deep cerebral veins in any subject. Flow was detected in the IJV and VV in all study participants. Amongst 199 participants there was one MS subject who fulfilled the minimum two ultrasound criteria for CCSVI. Using MRI we found no significant differences in either the intra- or extra-cranial venous flow velocity or venous architecture between cases and controls. CONCLUSION: This case-control study provides compelling evidence against the involvement of CCSVI in multiple sclerosis.", "link"=>"http://www.mendeley.com/research/evidence-against-involvement-chronic-cerebrospinal-venous-abnormalities-multiple-sclerosis-casecontr", "reader_count"=>9, "reader_count_by_academic_status"=>{"Researcher"=>2, "Student > Ph. D. Student"=>3, "Student > Master"=>2, "Student > Bachelor"=>2}, "reader_count_by_user_role"=>{"Researcher"=>2, "Student > Ph. D. Student"=>3, "Student > Master"=>2, "Student > Bachelor"=>2}, "reader_count_by_subject_area"=>{"Nursing and Health Professions"=>2, "Agricultural and Biological Sciences"=>1, "Medicine and Dentistry"=>5, "Psychology"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>5}, "Psychology"=>{"Psychology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}}, "reader_count_by_country"=>{"Canada"=>1, "Ghana"=>1}, "group_count"=>0}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84881535186"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84881535186?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84881535186&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84881535186&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84881535186", "dc:identifier"=>"SCOPUS_ID:84881535186", "eid"=>"2-s2.0-84881535186", "dc:title"=>"Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study", "dc:creator"=>"Rodger I.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"8", "prism:issueIdentifier"=>"8", "prism:pageRange"=>nil, "prism:coverDate"=>"2013-08-14", "prism:coverDisplayDate"=>"14 August 2013", "prism:doi"=>"10.1371/journal.pone.0072495", "citedby-count"=>"13", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"McMaster University, Faculty of Health Sciences", "affiliation-city"=>"Hamilton", "affiliation-country"=>"Canada"}], "pubmed-id"=>"23967312", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e72495", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0072495", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Journal Comments | Further Information

Twitter

Counter

  • {"month"=>"8", "year"=>"2013", "pdf_views"=>"200", "xml_views"=>"11", "html_views"=>"2118"}
  • {"month"=>"9", "year"=>"2013", "pdf_views"=>"69", "xml_views"=>"1", "html_views"=>"784"}
  • {"month"=>"10", "year"=>"2013", "pdf_views"=>"23", "xml_views"=>"4", "html_views"=>"261"}
  • {"month"=>"11", "year"=>"2013", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"147"}
  • {"month"=>"12", "year"=>"2013", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"93"}
  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"111"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"3", "html_views"=>"121"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"74"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"72"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"96"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"115"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"57"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"55"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"9", "xml_views"=>"1", "html_views"=>"53"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"64"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"54"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"104"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"31"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"35"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"39"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"38"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"110"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"26"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"74"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"44"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"38"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"52"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"41"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"71"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"68"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"75"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"98"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"29"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"2", "html_views"=>"59"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"100"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"114"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"3", "html_views"=>"102"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"176"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"122"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"54"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"4"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"7", "html_views"=>"8"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"2"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"5"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"1", "html_views"=>"3"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"7"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"5"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"1"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"16", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"8"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1170162"], "description"=>"<p>No significant differences were found between MS subjects and controls.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics", "ms", "patients", "matched", "controls", "ijvs", "mid-neck", "regions"], "article_id"=>772851, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.g001", "stats"=>{"downloads"=>2, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Comparison_of_absolute_mean_flow_values_mL_min_177_SD_between_MS_patients_blue_and_their_matched_controls_red_measured_in_the_right_and_left_IJVs_at_the_high_neck_and_mid_neck_regions_as_well_as_in_the_straight_sinus_/772851", "title"=>"Comparison of absolute mean flow values (mL/min ± SD) between MS patients (blue) and their matched controls (red) measured in the right and left IJVs at the high neck and mid-neck regions as well as in the straight sinus.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170163"], "description"=>"<p>IJV: Internal jugular veins; SD: standard deviation.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics", "asymmetry", "cases", "controls", "mid-neck"], "article_id"=>772852, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.t005", "stats"=>{"downloads"=>2, "page_views"=>17, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Differences_in_flow_asymmetry_right_8211_left_between_cases_and_controls_for_the_upper_and_mid_neck_IJV_/772852", "title"=>"Differences in flow asymmetry (right – left) between cases and controls for the upper and mid-neck IJV.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170164"], "description"=>"1<p>data missing for one subject test of Zamboni Rule using exact conditional logistic regression: p-value  = 0.991 OR and 95% CI not estimable.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics"], "article_id"=>772853, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.t004", "stats"=>{"downloads"=>1, "page_views"=>14, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Zamboni_Rule_/772853", "title"=>"Zamboni Rule.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170165"], "description"=>"<p>Clinical and Demographic Data.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics"], "article_id"=>772854, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.t001", "stats"=>{"downloads"=>1, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Clinical_and_Demographic_Data_/772854", "title"=>"Clinical and Demographic Data.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170167"], "description"=>"1<p>data missing for one subject.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics"], "article_id"=>772856, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.t003", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Zamboni_Criteria_/772856", "title"=>"Zamboni Criteria.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170168"], "description"=>"1<p>data missing for one subject.</p>2<p>values based on exact conditional logistic regression (case vs control).</p>3<p>defined as ΔCSA (supine - upright) <0.</p>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics"], "article_id"=>772857, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0072495.t002", "stats"=>{"downloads"=>1, "page_views"=>18, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Zamboni_Criteria_/772857", "title"=>"Zamboni Criteria.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2013-08-14 03:45:59"}
  • {"files"=>["https://ndownloader.figshare.com/files/1170180", "https://ndownloader.figshare.com/files/1170181", "https://ndownloader.figshare.com/files/1170182", "https://ndownloader.figshare.com/files/1170184", "https://ndownloader.figshare.com/files/1170185", "https://ndownloader.figshare.com/files/1170186"], "description"=>"<div><p>Objective</p><p>Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS. Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous insufficiency (CCSVI), has been advanced. The objective of this study was to evaluate the relative prevalence of the venous abnormalities that define CCSVI.</p><p>Methods</p><p>A case-control study was conducted in which 100 MS patients aged between 18–65 y meeting the revised McDonald criteria were randomly selected and stratified into one of four MS subtypes: relapsing/remitting, secondary progressive, primary progressive and benign. Control subjects (16–70 y) with no known history of MS or other neurological condition were matched with the MS cases. All cases and controls underwent ultrasound imaging of the veins of the neck plus the deep cerebral veins, and magnetic resonance imaging of the neck veins and brain. These procedures were performed on each participant on the same day.</p><p>Results</p><p>On ultrasound we found no evidence of reflux, stenosis or blockage in the internal jugular veins (IJV) or vertebral veins (VV) in any study participant. Similarly, there was no evidence of either reflux or cessation of flow in the deep cerebral veins in any subject. Flow was detected in the IJV and VV in all study participants. Amongst 199 participants there was one MS subject who fulfilled the minimum two ultrasound criteria for CCSVI. Using MRI we found no significant differences in either the intra- or extra-cranial venous flow velocity or venous architecture between cases and controls.</p><p>Conclusion</p><p>This case-control study provides compelling evidence against the involvement of CCSVI in multiple sclerosis.</p></div>", "links"=>[], "tags"=>["Clinical research design", "Case-control studies", "neurology", "Demyelinating disorders", "Multiple sclerosis", "Neurodegenerative diseases", "neuroimaging", "radiology", "Diagnostic radiology", "Magnetic resonance imaging", "ultrasonography", "Medical physics", "cerebrospinal", "venous", "abnormalities", "case-control"], "article_id"=>772863, "categories"=>["Medicine"], "users"=>["Ian W. Rodger", "Dorothy Dilar", "Janet Dwyer", "John Bienenstock", "Andu Coret", "Judith Coret-Simon", "Gary Foster", "Arlene Franchetto", "Slobodan Franic", "Charles H. Goldsmith", "David Koff", "Norman B. Konyer", "Mitchell Levine", "Ellen McDonald", "Michael D. Noseworthy", "John Paulseth", "Luciana Ribeiro", "Mary Jane Sayles", "Lehana Thabane"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0072495.s001", "https://dx.doi.org/10.1371/journal.pone.0072495.s002", "https://dx.doi.org/10.1371/journal.pone.0072495.s003", "https://dx.doi.org/10.1371/journal.pone.0072495.s004", "https://dx.doi.org/10.1371/journal.pone.0072495.s005", "https://dx.doi.org/10.1371/journal.pone.0072495.s006"], "stats"=>{"downloads"=>4, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Evidence_against_the_Involvement_of_Chronic_Cerebrospinal_Venous_Abnormalities_in_Multiple_Sclerosis_A_Case_Control_Study_/772863", "title"=>"Evidence against the Involvement of Chronic Cerebrospinal Venous Abnormalities in Multiple Sclerosis. A Case-Control Study", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2013-08-14 03:45:59"}

PMC Usage Stats | Further Information

  • {"unique-ip"=>"23", "full-text"=>"30", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"8"}
  • {"unique-ip"=>"63", "full-text"=>"57", "pdf"=>"32", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"12", "cited-by"=>"0", "year"=>"2013", "month"=>"9"}
  • {"unique-ip"=>"30", "full-text"=>"31", "pdf"=>"21", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2013", "month"=>"10"}
  • {"unique-ip"=>"24", "full-text"=>"25", "pdf"=>"20", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2013", "month"=>"11"}
  • {"unique-ip"=>"26", "full-text"=>"34", "pdf"=>"11", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"8", "cited-by"=>"0", "year"=>"2013", "month"=>"12"}
  • {"unique-ip"=>"15", "full-text"=>"18", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"13", "full-text"=>"12", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"16", "full-text"=>"16", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"11", "full-text"=>"15", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"11", "full-text"=>"13", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"10", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"13", "full-text"=>"11", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"4", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"12", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"17", "full-text"=>"17", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"1", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"10", "full-text"=>"6", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"15", "full-text"=>"12", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"13", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"2", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"9", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"9", "full-text"=>"14", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"6", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}

Relative Metric

{"start_date"=>"2013-01-01T00:00:00Z", "end_date"=>"2013-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Medicine and health sciences/Clinical medicine", "average_usage"=>[263, 451, 582, 699, 797, 889, 969, 1045, 1134, 1215, 1284, 1362, 1412]}, {"subject_area"=>"/Medicine and health sciences/Diagnostic medicine", "average_usage"=>[244, 425, 535, 636, 728, 814, 900, 982, 1063, 1139, 1221, 1296, 1361]}, {"subject_area"=>"/Medicine and health sciences/Immunology", "average_usage"=>[262, 463, 587, 693, 790, 882, 965, 1051, 1135, 1218, 1300, 1376, 1438]}, {"subject_area"=>"/Medicine and health sciences/Pathology and laboratory medicine", "average_usage"=>[267, 466, 592, 709, 806, 901, 989, 1075, 1162, 1254, 1342, 1424, 1486]}, {"subject_area"=>"/Medicine and health sciences/Radiology and imaging", "average_usage"=>[230, 403, 513, 618, 711, 806, 896, 985, 1065, 1141, 1225, 1296, 1360]}, {"subject_area"=>"/Medicine and health sciences/Surgical and invasive medical procedures", "average_usage"=>[223, 396, 511, 599, 690, 775, 859, 936, 1012, 1090, 1168, 1237, 1299]}]}
Loading … Spinner
There are currently no alerts