Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Loss of social behaviours in populations of Pseudomonas aeruginosa infecting lungs of patients with cystic fibrosis", "type"=>"journal", "authors"=>[{"first_name"=>"Natalie", "last_name"=>"Jiricny", "scopus_author_id"=>"26030939800"}, {"first_name"=>"Søren", "last_name"=>"Molin", "scopus_author_id"=>"57197278680"}, {"first_name"=>"Kevin", "last_name"=>"Foster", "scopus_author_id"=>"7202155866"}, {"first_name"=>"Stephen P.", "last_name"=>"Diggle", "scopus_author_id"=>"6603118427"}, {"first_name"=>"Pauline D.", "last_name"=>"Scanlan", "scopus_author_id"=>"16025480800"}, {"first_name"=>"Melanie", "last_name"=>"Ghoul", "scopus_author_id"=>"55859644800"}, {"first_name"=>"Helle Krogh", "last_name"=>"Johansen", "scopus_author_id"=>"7103282692"}, {"first_name"=>"Lorenzo A.", "last_name"=>"Santorelli", "scopus_author_id"=>"6508294873"}, {"first_name"=>"Roman", "last_name"=>"Popat", "scopus_author_id"=>"24802463400"}, {"first_name"=>"Stuart A.", "last_name"=>"West", "scopus_author_id"=>"7402556620"}, {"first_name"=>"Ashleigh S.", "last_name"=>"Griffin", "scopus_author_id"=>"7202675806"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"84897975157", "doi"=>"10.1371/journal.pone.0083124", "pui"=>"372801743", "pmid"=>"24454693", "scopus"=>"2-s2.0-84897975157", "issn"=>"19326203", "isbn"=>"1932-6203 (Electronic)\\r1932-6203 (Linking)"}, "id"=>"7cd1c557-3390-32bf-ae41-f3773aeceb9f", "abstract"=>"Pseudomonas aeruginosa, is an opportunistic, bacterial pathogen causing persistent and frequently fatal infections of the lung in patients with cystic fibrosis. Isolates from chronic infections differ from laboratory and environmental strains in a range of traits and this is widely interpreted as the result of adaptation to the lung environment. Typically, chronic strains carry mutations in global regulation factors that could effect reduced expression of social traits, raising the possibility that competitive dynamics between cooperative and selfish, cheating strains could also drive changes in P. aeruginosa infections. We compared the expression of cooperative traits - biofilm formation, secretion of exo-products and quorum sensing (QS) - in P. aeruginosa isolates that were estimated to have spent different lengths of time in the lung based on clinical information. All three exo-products involved in nutrient acquisition were produced in significantly smaller quantities with increased duration of infection, and patterns across four QS signal molecules were consistent with accumulation over time of mutations in lasR, which are known to disrupt the ability of cells to respond to QS signal. Pyocyanin production, and the proportion of cells in biofilm relative to motile, free-living cells in liquid culture, did not change. Overall, our results confirm that the loss of social behaviour is a consistent trend with time spent in the lung and suggest that social dynamics are potentially relevant to understanding the behaviour of P. aeruginosa in lung infections.", "link"=>"http://www.mendeley.com/research/loss-social-behaviours-populations-pseudomonas-aeruginosa-infecting-lungs-patients-cystic-fibrosis", "reader_count"=>78, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Professor > Associate Professor"=>4, "Librarian"=>1, "Student > Doctoral Student"=>7, "Researcher"=>13, "Student > Ph. D. Student"=>19, "Student > Postgraduate"=>4, "Student > Master"=>11, "Student > Bachelor"=>12, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>3}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Professor > Associate Professor"=>4, "Librarian"=>1, "Student > Doctoral Student"=>7, "Researcher"=>13, "Student > Ph. D. Student"=>19, "Student > Postgraduate"=>4, "Student > Master"=>11, "Student > Bachelor"=>12, "Lecturer"=>2, "Lecturer > Senior Lecturer"=>1, "Professor"=>3}, "reader_count_by_subject_area"=>{"Engineering"=>3, "Unspecified"=>3, "Environmental Science"=>1, "Biochemistry, Genetics and Molecular Biology"=>12, "Nursing and Health Professions"=>1, "Agricultural and Biological Sciences"=>40, "Medicine and Dentistry"=>3, "Pharmacology, Toxicology and Pharmaceutical Science"=>2, "Chemistry"=>2, "Social Sciences"=>1, "Immunology and Microbiology"=>9, "Earth and Planetary Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>3}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Chemistry"=>{"Chemistry"=>2}, "Social Sciences"=>{"Social Sciences"=>1}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>9}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>40}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>12}, "Unspecified"=>{"Unspecified"=>3}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>2}}, "reader_count_by_country"=>{"Austria"=>1, "United States"=>1, "Japan"=>1, "Denmark"=>1, "France"=>1, "Germany"=>2}, "group_count"=>1}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84897975157"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84897975157?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84897975157&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84897975157&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84897975157", "dc:identifier"=>"SCOPUS_ID:84897975157", "eid"=>"2-s2.0-84897975157", "dc:title"=>"Loss of social behaviours in populations of Pseudomonas aeruginosa infecting lungs of patients with cystic fibrosis", "dc:creator"=>"Jiricny N.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"9", "prism:issueIdentifier"=>"1", "prism:pageRange"=>nil, "prism:coverDate"=>"2014-01-14", "prism:coverDisplayDate"=>"14 January 2014", "prism:doi"=>"10.1371/journal.pone.0083124", "citedby-count"=>"38", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"University of Oxford", "affiliation-city"=>"Oxford", "affiliation-country"=>"United Kingdom"}], "pubmed-id"=>"24454693", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e83124", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0083124", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Twitter

Counter

  • {"month"=>"1", "year"=>"2014", "pdf_views"=>"113", "xml_views"=>"15", "html_views"=>"721"}
  • {"month"=>"2", "year"=>"2014", "pdf_views"=>"54", "xml_views"=>"0", "html_views"=>"185"}
  • {"month"=>"3", "year"=>"2014", "pdf_views"=>"39", "xml_views"=>"2", "html_views"=>"172"}
  • {"month"=>"4", "year"=>"2014", "pdf_views"=>"38", "xml_views"=>"2", "html_views"=>"171"}
  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"19", "xml_views"=>"0", "html_views"=>"139"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"20", "xml_views"=>"0", "html_views"=>"113"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"15", "xml_views"=>"1", "html_views"=>"116"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"2", "html_views"=>"66"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"53"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"66"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"20", "xml_views"=>"2", "html_views"=>"75"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"3", "html_views"=>"56"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"72"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"39"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"48"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"1", "html_views"=>"42"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"30"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"14", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"33"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"13", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"29"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"31"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"30"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"37"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"53"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"36"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"43"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"25"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"52"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"3", "html_views"=>"31"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"25"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"21"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"34"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"78"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"6", "xml_views"=>"2", "html_views"=>"38"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"1"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"9"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"10"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"14"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"3", "html_views"=>"11"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"19"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"7"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"9"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"4"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"12", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"7", "xml_views"=>"5", "html_views"=>"8"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"9", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"4", "year"=>"2020", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"5", "year"=>"2020", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"3"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1347075"], "description"=>"<p>Protease and elastase activity calculated as <i>A</i><sub>440</sub>/<i>A</i><sub>600</sub> and <i>A</i><sub>495</sub>/<i>A</i><sub>600</sub>, respectively. Data shown as untransformed averages of five replicates per isolate per category ±SE.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "ezymes", "protease", "elastase"], "article_id"=>900827, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g004", "stats"=>{"downloads"=>0, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_production_of_ezymes_protease_a_and_elastase_b_of_the_four_P_aeruginosa_isolate_categories_/900827", "title"=>"The production of ezymes protease (a) and elastase (b) of the four <i>P. aeruginosa</i> isolate categories.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347074"], "description"=>"<p>Data shown as untransformed averages of five replicates per isolate per category ±SE.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections"], "article_id"=>900826, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g003", "stats"=>{"downloads"=>4, "page_views"=>26, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Pyocyanin_production_of_the_four_P_aeruginosa_isolate_categories_/900826", "title"=>"Pyocyanin production of the four <i>P. aeruginosa</i> isolate categories.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347077"], "description"=>"<p>Data shown as untransformed averages of single replicates per isolate per category ±SE.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "3-oxo-c12-hsl", "pqs", "interpreted"], "article_id"=>900829, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g006", "stats"=>{"downloads"=>5, "page_views"=>34, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Relative_production_of_a_3_oxo_C12_HSL_and_b_C_4_HSL_c_PQS_and_d_C_7_HHQ_interpreted_from_LC_MS_peak_readings_/900829", "title"=>"Relative production of (a) 3-oxo-C12-HSL and (b) C<sub>4</sub>-HSL (c) PQS and (d) C<sub>7</sub>-HHQ interpreted from LC/MS peak readings.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347076"], "description"=>"<p>Data shown as untransformed averages of five replicates per isolate per category ±SE.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "cells", "microtitre", "biofilm"], "article_id"=>900828, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g005", "stats"=>{"downloads"=>0, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_percentage_of_cells_in_microtitre_culture_existing_in_biofilm_of_the_four_P_aeruginosa_isolate_categories_/900828", "title"=>"The percentage of cells in microtitre culture existing in biofilm of the four <i>P. aeruginosa</i> isolate categories.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347073"], "description"=>"<p>Pyoverdin production calculated as RFU<sub>400,460</sub>/<i>A</i><sub>600</sub>. Data shown as untransformed averages of five replicates per isolate per category ±SE.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "pyoverdin"], "article_id"=>900825, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g002", "stats"=>{"downloads"=>1, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_estimated_pyoverdin_production_per_cell_of_the_four_P_aeruginosa_isolate_categories_/900825", "title"=>"The estimated pyoverdin production per cell of the four <i>P. aeruginosa</i> isolate categories.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347072"], "description"=>"<p>A table summarising statistical analyses and trends in expression over time across all traits.</p>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "summarising", "trends"], "article_id"=>900824, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124.g001", "stats"=>{"downloads"=>1, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_A_table_summarising_statistical_analyses_and_trends_in_expression_over_time_across_all_traits_/900824", "title"=>"A table summarising statistical analyses and trends in expression over time across all traits.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-14 03:16:05"}
  • {"files"=>["https://ndownloader.figshare.com/files/1347079"], "description"=>"<div><p><i>Pseudomonas aeruginosa</i>, is an opportunistic, bacterial pathogen causing persistent and frequently fatal infections of the lung in patients with cystic fibrosis. Isolates from chronic infections differ from laboratory and environmental strains in a range of traits and this is widely interpreted as the result of adaptation to the lung environment. Typically, chronic strains carry mutations in global regulation factors that could effect reduced expression of social traits, raising the possibility that competitive dynamics between cooperative and selfish, cheating strains could also drive changes in <i>P. aeruginosa</i> infections. We compared the expression of cooperative traits - biofilm formation, secretion of exo-products and quorum sensing (QS) - in <i>P. aeruginosa</i> isolates that were estimated to have spent different lengths of time in the lung based on clinical information. All three exo-products involved in nutrient acquisition were produced in significantly smaller quantities with increased duration of infection, and patterns across four QS signal molecules were consistent with accumulation over time of mutations in <i>lasR</i>, which are known to disrupt the ability of cells to respond to QS signal. Pyocyanin production, and the proportion of cells in biofilm relative to motile, free-living cells in liquid culture, did not change. Overall, our results confirm that the loss of social behaviour is a consistent trend with time spent in the lung and suggest that social dynamics are potentially relevant to understanding the behaviour of <i>P. aeruginosa</i> in lung infections.</p></div>", "links"=>[], "tags"=>["developmental biology", "Microbial growth and development", "ecology", "microbial ecology", "Evolutionary biology", "Organismal evolution", "Microbial evolution", "microbiology", "bacteriology", "Bacterial biofilms", "Microbial physiology", "Anatomy and physiology", "Respiratory system", "Infectious diseases", "Bacterial diseases", "Pseudomonas infections", "Pulmonology", "Respiratory infections", "behaviours", "populations", "infecting", "lungs", "patients", "cystic", "fibrosis"], "article_id"=>900831, "categories"=>["Biological Sciences", "Medicine"], "users"=>["Natalie Jiricny", "Søren Molin", "Kevin Foster", "Stephen P. Diggle", "Pauline D. Scanlan", "Melanie Ghoul", "Helle Krogh Johansen", "Lorenzo A. Santorelli", "Roman Popat", "Stuart A. West", "Ashleigh S. Griffin"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0083124", "stats"=>{"downloads"=>0, "page_views"=>19, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/Loss_of_Social_Behaviours_in_Populations_of_Pseudomonas_aeruginosa_Infecting_Lungs_of_Patients_with_Cystic_Fibrosis/900831", "title"=>"Loss of Social Behaviours in Populations of <i>Pseudomonas aeruginosa</i> Infecting Lungs of Patients with Cystic Fibrosis", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-01-14 03:16:05"}

PMC Usage Stats | Further Information

  • {"unique-ip"=>"34", "full-text"=>"29", "pdf"=>"25", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"1"}
  • {"unique-ip"=>"42", "full-text"=>"40", "pdf"=>"18", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"2"}
  • {"unique-ip"=>"34", "full-text"=>"33", "pdf"=>"19", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"15", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"3"}
  • {"unique-ip"=>"19", "full-text"=>"22", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"13", "full-text"=>"15", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"23", "full-text"=>"26", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"4"}
  • {"unique-ip"=>"16", "full-text"=>"17", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"27", "full-text"=>"26", "pdf"=>"14", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"18", "full-text"=>"17", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"28", "full-text"=>"32", "pdf"=>"17", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"18", "full-text"=>"20", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"10", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"20", "full-text"=>"20", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"23", "full-text"=>"23", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"1", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"14", "full-text"=>"10", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"14", "full-text"=>"13", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"22", "full-text"=>"19", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"31", "full-text"=>"22", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"2", "cited-by"=>"3", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"14", "full-text"=>"11", "pdf"=>"3", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"12", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"19", "full-text"=>"16", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"3", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"29", "full-text"=>"30", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"15", "full-text"=>"17", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"7", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"7", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"1", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"3", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"2", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"10", "full-text"=>"10", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"6", "full-text"=>"3", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"3", "full-text"=>"4", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"8", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"7", "full-text"=>"12", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"3", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"7", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"24", "supp-data"=>"3", "cited-by"=>"2", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"1", "full-text"=>"1", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"6", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"4", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"1", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"6", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"9", "full-text"=>"10", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}
  • {"unique-ip"=>"8", "full-text"=>"12", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"2", "cited-by"=>"0", "year"=>"2020", "month"=>"3"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"4"}

Relative Metric

{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences/Cell biology", "average_usage"=>[286]}, {"subject_area"=>"/Biology and life sciences/Ecology", "average_usage"=>[331]}, {"subject_area"=>"/Biology and life sciences/Organisms", "average_usage"=>[310]}, {"subject_area"=>"/Ecology and environmental sciences/Ecology", "average_usage"=>[313]}, {"subject_area"=>"/Medicine and health sciences/Pulmonology", "average_usage"=>[261, 417]}]}
Loading … Spinner
There are currently no alerts