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{"title"=>"Feasibility and safety of fiber optic micro-imaging in canine peripheral airways", "type"=>"journal", "authors"=>[{"first_name"=>"Yijun", "last_name"=>"Liu", "scopus_author_id"=>"56061981300"}, {"first_name"=>"Bingbing", "last_name"=>"Yan", "scopus_author_id"=>"55864702500"}, {"first_name"=>"Ziyang", "last_name"=>"Huang", "scopus_author_id"=>"56061833100"}, {"first_name"=>"Rui", "last_name"=>"Guo", "scopus_author_id"=>"36547895300"}, {"first_name"=>"Jingxing", "last_name"=>"Wu", "scopus_author_id"=>"55864648000"}, {"first_name"=>"Xun", "last_name"=>"Liu", "scopus_author_id"=>"55865544200"}, {"first_name"=>"Kaiqing", "last_name"=>"Yao", "scopus_author_id"=>"55206135800"}, {"first_name"=>"Fajin", "last_name"=>"Lv", "scopus_author_id"=>"16070074700"}, {"first_name"=>"Huisheng", "last_name"=>"Deng", "scopus_author_id"=>"55254365800"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"sgr"=>"84897558783", "scopus"=>"2-s2.0-84897558783", "doi"=>"10.1371/journal.pone.0084829", "pui"=>"372763063", "issn"=>"19326203", "pmid"=>"24416294"}, "id"=>"a9c2e531-e1dd-3f77-b92b-311ee4876472", "abstract"=>"Purpose: To assess the feasibility and safety of imaging canine peripheral airways (<1 mm) with an experimental micro-imaging fiber optic bronchoscope. Methods: Twenty healthy dogs were scoped with a micro-imaging fiber optic bronchoscope (0.8 mm outer diameter). Images at various levels of the bronchioles, mucosal color, and tracheal secretions were recorded. The apparatus was stopped once it was difficult to insert. CT imaging was performed simultaneously to monitor progression. The safety of the device was evaluated by monitoring heart rate (HR), respiratory rate (RR), mean artery pressure (MAP), peripheral oxygen saturation (SpO2) and arterial blood gases (partial pressure of arterial carbon-dioxide, PaCO2, partial pressure of arterial oxygen, PaO2, and blood pH). Results: (1) According to the CT scan, the micro-imaging fiber was able to access the peripheral airways (<1 mm) in canines. (2) There was no significant change in the values of HR, MAP, pH and PaCO2 during the procedure (P>0.05). Comparing pre-manipulation and post-manipulation values, SpO2 (F = 13.06, P<0.05) and PaO2 (F = 3.01, P = 0.01) were decreased, whereas RR (F = 3.85, P<0.05) was elevated during the manipulation. (3) Self-limited bleeding was observed in one dog; severe bleeding or other complications did not occur. Conclusion: Although the new apparatus had little effect on SpO2, PaO2 and RR, it can probe into small peripheral airways (<1 mm), which may provide a new platform for the early diagnosis of bronchiolar diseases. [ABSTRACT FROM AUTHOR]", "link"=>"http://www.mendeley.com/research/feasibility-safety-fiber-optic-microimaging-canine-peripheral-airways", "reader_count"=>6, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>1, "Other"=>2, "Student > Bachelor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>1, "Other"=>2, "Student > Bachelor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Engineering"=>1, "Medicine and Dentistry"=>2, "Psychology"=>1, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>2}, "Psychology"=>{"Psychology"=>1}, "Computer Science"=>{"Computer Science"=>1}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>1}

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• {"files"=>["https://ndownloader.figshare.com/files/1343767"], "description"=>"<p>Real-time imaging provides peripheral bronchial intraluminal information and peripheral bronchial branches in a healthy canine.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "Anatomy and physiology", "cardiovascular system", "cardiovascular", "Cardiovascular imaging", "Diagnostic medicine", "Test evaluation", "Pulmonology", "radiology", "Diagnostic radiology", "echocardiography", "Nuclear medicine", "Radionuclide imaging", "surgery", "imaging", "provides", "peripheral", "bronchial", "intraluminal", "branches"], "article_id"=>898312, "categories"=>["Biological Sciences", "Medicine", "Engineering"], "users"=>["Yijun Liu", "Bingbing Yan", "Ziyang Huang", "Rui Guo", "Jingxing Wu", "Xun Liu", "Kaiqing Yao", "Fajin Lv", "Huisheng Deng"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0084829.g003", "stats"=>{"downloads"=>0, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Real_time_imaging_provides_peripheral_bronchial_intraluminal_information_and_peripheral_bronchial_branches_in_a_healthy_canine_/898312", "title"=>"Real-time imaging provides peripheral bronchial intraluminal information and peripheral bronchial branches in a healthy canine.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-09 03:11:47"}
• {"files"=>["https://ndownloader.figshare.com/files/1343764"], "description"=>"<p>of the entire micro-imaging fiber, showing the body of the fiberscope, objective lens, and connection to camera.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "Anatomy and physiology", "cardiovascular system", "cardiovascular", "Cardiovascular imaging", "Diagnostic medicine", "Test evaluation", "Pulmonology", "radiology", "Diagnostic radiology", "echocardiography", "Nuclear medicine", "Radionuclide imaging", "surgery", "micro-imaging"], "article_id"=>898309, "categories"=>["Biological Sciences", "Medicine", "Engineering"], "users"=>["Yijun Liu", "Bingbing Yan", "Ziyang Huang", "Rui Guo", "Jingxing Wu", "Xun Liu", "Kaiqing Yao", "Fajin Lv", "Huisheng Deng"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0084829.g001", "stats"=>{"downloads"=>0, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_of_the_entire_micro_imaging_fiber_showing_the_body_of_the_fiberscope_objective_lens_and_connection_to_camera_/898309", "title"=>"of the entire micro-imaging fiber, showing the body of the fiberscope, objective lens, and connection to camera.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-09 03:11:47"}
• {"files"=>["https://ndownloader.figshare.com/files/1343765"], "description"=>"<p>The tip of the micro-imaging fiber extending to the peripheral bronchioles in a canine.</p>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "Anatomy and physiology", "cardiovascular system", "cardiovascular", "Cardiovascular imaging", "Diagnostic medicine", "Test evaluation", "Pulmonology", "radiology", "Diagnostic radiology", "echocardiography", "Nuclear medicine", "Radionuclide imaging", "surgery", "micro-imaging", "extending", "peripheral", "bronchioles"], "article_id"=>898310, "categories"=>["Biological Sciences", "Medicine", "Engineering"], "users"=>["Yijun Liu", "Bingbing Yan", "Ziyang Huang", "Rui Guo", "Jingxing Wu", "Xun Liu", "Kaiqing Yao", "Fajin Lv", "Huisheng Deng"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0084829.g002", "stats"=>{"downloads"=>3, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_tip_of_the_micro_imaging_fiber_extending_to_the_peripheral_bronchioles_in_a_canine_/898310", "title"=>"The tip of the micro-imaging fiber extending to the peripheral bronchioles in a canine.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-01-09 03:11:47"}
• {"files"=>["https://ndownloader.figshare.com/files/1343771", "https://ndownloader.figshare.com/files/1343772"], "description"=>"<div><p>Purpose</p><p>To assess the feasibility and safety of imaging canine peripheral airways (<1 mm) with an experimental micro-imaging fiber optic bronchoscope.</p><p>Methods</p><p>Twenty healthy dogs were scoped with a micro-imaging fiber optic bronchoscope (0.8 mm outer diameter). Images at various levels of the bronchioles, mucosal color, and tracheal secretions were recorded. The apparatus was stopped once it was difficult to insert. CT imaging was performed simultaneously to monitor progression. The safety of the device was evaluated by monitoring heart rate (HR), respiratory rate (RR), mean artery pressure (MAP), peripheral oxygen saturation (SpO₂) and arterial blood gases (partial pressure of arterial carbon-dioxide, PaCO₂, partial pressure of arterial oxygen, PaO₂, and blood pH).</p><p>Results</p><p>(1) According to the CT scan, the micro-imaging fiber was able to access the peripheral airways (<1 mm) in canines. (2) There was no significant change in the values of HR, MAP, pH and PaCO₂ during the procedure (P>0.05). Comparing pre-manipulation and post-manipulation values, SpO₂ (F = 13.06, P<0.05) and PaO₂ (F = 3.01, P = 0.01) were decreased, whereas RR (F = 3.85, P<0.05) was elevated during the manipulation. (3) Self-limited bleeding was observed in one dog; severe bleeding or other complications did not occur.</p><p>Conclusion</p><p>Although the new apparatus had little effect on SpO₂, PaO₂ and RR, it can probe into small peripheral airways (<1 mm), which may provide a new platform for the early diagnosis of bronchiolar diseases.</p></div>", "links"=>[], "tags"=>["biotechnology", "Bioengineering", "Biomedical Engineering", "Anatomy and physiology", "cardiovascular system", "cardiovascular", "Cardiovascular imaging", "Diagnostic medicine", "Test evaluation", "Pulmonology", "radiology", "Diagnostic radiology", "echocardiography", "Nuclear medicine", "Radionuclide imaging", "surgery", "optic", "micro-imaging", "canine", "peripheral"], "article_id"=>898316, "categories"=>["Biological Sciences", "Medicine", "Engineering"], "users"=>["Yijun Liu", "Bingbing Yan", "Ziyang Huang", "Rui Guo", "Jingxing Wu", "Xun Liu", "Kaiqing Yao", "Fajin Lv", "Huisheng Deng"], "doi"=>["https://dx.doi.org/10.1371/journal.pone.0084829.s001", "https://dx.doi.org/10.1371/journal.pone.0084829.s002"], "stats"=>{"downloads"=>0, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Feasibility_and_Safety_of_Fiber_Optic_Micro_Imaging_in_Canine_Peripheral_Airways_/898316", "title"=>"Feasibility and Safety of Fiber Optic Micro-Imaging in Canine Peripheral Airways", "pos_in_sequence"=>0, "defined_type"=>4, "published_date"=>"2014-01-09 03:11:47"}

PMC Usage Stats | Further Information

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Relative Metric

{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Medicine and health sciences/Anatomy", "average_usage"=>[266]}, {"subject_area"=>"/Medicine and health sciences/Diagnostic medicine", "average_usage"=>[257]}, {"subject_area"=>"/Medicine and health sciences/Oncology", "average_usage"=>[266]}, {"subject_area"=>"/Medicine and health sciences/Pathology and laboratory medicine", "average_usage"=>[287]}, {"subject_area"=>"/Medicine and health sciences/Vascular medicine", "average_usage"=>[248]}]}

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