Drug-Related Problems in Patients with Benign Prostatic Hyperplasia: A Cross Sectional Retrospective Study
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{"title"=>"Drug-related problems in patients with benign prostatic hyperplasia: A cross sectional retrospective study", "type"=>"journal", "authors"=>[{"first_name"=>"Hasniza Zaman", "last_name"=>"Huri", "scopus_author_id"=>"34976838600"}, {"first_name"=>"Chong Hui", "last_name"=>"Xin", "scopus_author_id"=>"56155245800"}, {"first_name"=>"Che Zuraini", "last_name"=>"Sulaiman", "scopus_author_id"=>"24475541000"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"24475089", "doi"=>"10.1371/journal.pone.0086215", "sgr"=>"84900339339", "scopus"=>"2-s2.0-84900339339", "issn"=>"19326203", "pui"=>"373059223"}, "id"=>"be3359d2-2c8e-342f-a1a5-060acc69f1ca", "abstract"=>"Benign Prostatic Hyperplasia (BPH) patients are at risk of acquiring drug-related problems (DRPs), as it is present in the majority of aging men. To date, DRPs among BPH patients have not been well studied. We conducted this retrospective study in a tertiary hospital in Malaysia from January 2009 to June 2012 with the aim of identifying the factors associated with DRPs among BPH patients. The Pharmaceutical Care Network Europe Classification Version (PCNE) 5.01 was used as a tool to classify DRPs. We enrolled 203 patients from 259 hospital admissions. A total of 390 DRPs were found and there was an average of 1.5±1.3 problems per hospitalization. 76.1% of hospital admissions included at least one DRP. The most common DRP categories encountered were drug choice problems (45.9%), drug interactions (24.9%), and dosing problems (13.3%). Factors such as advanced age (p = 0.005), a hospital stay of more than 6 days (p = 0.001), polydrug treatments (p<0.001), multiple comorbidities (p<0.001), and comorbid cardiovascular disease (p = 0.011), diabetes mellitus(p = 0.001), hypertension (p<0.001) and renal impairment (p = 0.011) were significantly associated with the occurrence of DRPs. These data indicated that the prevalence of DRPs is high among BPH patients. The identification of different subtypes of DRPs and the factors associated with DRPs may facilitate risk reduction for BPH patients.", "link"=>"http://www.mendeley.com/research/drugrelated-problems-patients-benign-prostatic-hyperplasia-cross-sectional-retrospective-study-2", "reader_count"=>22, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Student > Doctoral Student"=>4, "Student > Postgraduate"=>2, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>3, "Lecturer"=>2}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Student > Doctoral Student"=>4, "Student > Postgraduate"=>2, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>3, "Lecturer"=>2}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Environmental Science"=>1, "Medicine and Dentistry"=>8, "Agricultural and Biological Sciences"=>2, "Pharmacology, Toxicology and Pharmaceutical Science"=>6, "Business, Management and Accounting"=>1, "Chemistry"=>1, "Psychology"=>1, "Computer Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>8}, "Chemistry"=>{"Chemistry"=>1}, "Psychology"=>{"Psychology"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>2}, "Computer Science"=>{"Computer Science"=>1}, "Business, Management and Accounting"=>{"Business, Management and Accounting"=>1}, "Unspecified"=>{"Unspecified"=>1}, "Environmental Science"=>{"Environmental Science"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>6}}, "reader_count_by_country"=>{"United Kingdom"=>1}, "group_count"=>0}

Scopus | Further Information

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Relative Metric

{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/People and places/Population groupings", "average_usage"=>[300]}]}
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