Nasopharyngeal Carriage of Streptococcus pneumonia in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia
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{"title"=>"Nasopharyngeal carriage of Streptococcus pneumonia in pneumonia-prone age groups in Semarang, Java Island, Indonesia", "type"=>"journal", "authors"=>[{"first_name"=>"Helmia", "last_name"=>"Farida", "scopus_author_id"=>"11140500000"}, {"first_name"=>"Juliëtte A.", "last_name"=>"Severin", "scopus_author_id"=>"8700385500"}, {"first_name"=>"M. Hussein", "last_name"=>"Gasem", "scopus_author_id"=>"6508371601"}, {"first_name"=>"Monique", "last_name"=>"Keuter", "scopus_author_id"=>"6603776274"}, {"first_name"=>"Hendro", "last_name"=>"Wahyono", "scopus_author_id"=>"6503895640"}, {"first_name"=>"Peterhans", "last_name"=>"Van Den Broek", "scopus_author_id"=>"8875365500"}, {"first_name"=>"Peter W.M.", "last_name"=>"Hermans", "scopus_author_id"=>"7101909804"}, {"first_name"=>"Henri A.", "last_name"=>"Verbrugh", "scopus_author_id"=>"7103296623"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84900340915", "sgr"=>"84900340915", "issn"=>"19326203", "doi"=>"10.1371/journal.pone.0087431", "pmid"=>"24498104", "isbn"=>"1932-6203 (Electronic)\\n1932-6203 (Linking)", "pui"=>"373059531"}, "id"=>"7dda1912-479b-3a88-9f44-276b85f0e2c5", "abstract"=>"INTRODUCTION: Streptococcus pneumoniae is a worldwide occurring pathogen Nasopharyngeal carriage of Streptococcus pneumoniae precedes pneumonia and other pneumococcal diseases in the community. Little is known about S. pneumoniae carriage in Indonesia, complicating strategies to control pneumococcal diseases. We investigated nasopharyngeal carriage of S. pneumoniae in Semarang, Indonesia.\\n\\nMETHODS: A population-based survey was performed in Semarang, Indonesia. Nasopharyngeal swabs and questionnaires were taken from 496 healthy young (6-60 month-old) children and 45-70 year-old adults.\\n\\nRESULTS: Forty-three percent of children aged 6-60 months and 11% of adults aged 45-75 years carried S. pneumoniae. Determinants of carriage were being a child (OR 7.7; 95% CI = 4.5-13.0), passive smoking (OR 2.1; 95% CI = 1.3-3.4), and contact with toddler(s) at home (OR 3.0; 95% CI = 1.9-4.7). The most frequent serotypes found were 6A/B and 15B/C. The current commercially available vaccines cover <50% serotypes found in children. Twenty-four percent of S. pneumoniae strains were penicillin non-susceptible, and 45% were resistant to cotrimoxazol.\\n\\nCONCLUSIONS: The limited coverage of commercially available vaccines against the serotypes found in this population, and the high proportion of non-susceptibility to penicillin and cotrimoxazol suggest the need for region-specific information and strategies to control S. pneumoniae.", "link"=>"http://www.mendeley.com/research/nasopharyngeal-carriage-streptococcus-pneumonia-pneumoniaprone-age-groups-semarang-java-island-indon", "reader_count"=>54, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Researcher"=>12, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>3, "Student > Postgraduate"=>9, "Student > Master"=>5, "Other"=>5, "Student > Bachelor"=>11, "Lecturer"=>6, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Researcher"=>12, "Student > Doctoral Student"=>1, "Student > Ph. D. Student"=>3, "Student > Postgraduate"=>9, "Student > Master"=>5, "Other"=>5, "Student > Bachelor"=>11, "Lecturer"=>6, "Lecturer > Senior Lecturer"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Environmental Science"=>1, "Nursing and Health Professions"=>2, "Biochemistry, Genetics and Molecular Biology"=>1, "Medicine and Dentistry"=>35, "Agricultural and Biological Sciences"=>8, "Chemical Engineering"=>1, "Immunology and Microbiology"=>4, "Earth and Planetary Sciences"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>35}, "Immunology and Microbiology"=>{"Immunology and Microbiology"=>4}, "Earth and Planetary Sciences"=>{"Earth and Planetary Sciences"=>1}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>8}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>2}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>1}, "Unspecified"=>{"Unspecified"=>1}, "Environmental Science"=>{"Environmental Science"=>1}, "Chemical Engineering"=>{"Chemical Engineering"=>1}}, "reader_count_by_country"=>{"United States"=>1, "United Kingdom"=>1, "India"=>1, "Indonesia"=>1}, "group_count"=>4}

Scopus | Further Information

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