Identification and Validation of Quantitative Trait Loci (QTL) for Canine Hip Dysplasia (CHD) in German Shepherd Dogs
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  • {"files"=>["https://ndownloader.figshare.com/files/1487041"], "description"=>"<p>Number of German Shepherd Dogs included in the validation study. Distribution of the 843 dogs by canine hip dysplasia (CHD) score, sex and birth year is given.</p>", "links"=>[], "tags"=>["agriculture", "Animal management", "Computational biology", "genome analysis", "Genome-wide association studies", "Gene regulatory networks", "genetics", "Heredity", "Complex traits", "Animal genetics", "Genetics of disease", "Veterinary science", "Animal types", "Small animals", "Veterinary medicine", "Small animal care", "german", "shepherd", "dogs", "included", "validation", "843", "canine", "dysplasia"], "article_id"=>1018074, "categories"=>["Biological Sciences"], "users"=>["Lena Fels", "Ottmar Distl"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0096618.t006", "stats"=>{"downloads"=>1, "page_views"=>12, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Number_of_German_Shepherd_Dogs_included_in_the_validation_study_Distribution_of_the_843_dogs_by_canine_hip_dysplasia_CHD_score_sex_and_birth_year_is_given_/1018074", "title"=>"Number of German Shepherd Dogs included in the validation study. Distribution of the 843 dogs by canine hip dysplasia (CHD) score, sex and birth year is given.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-05-06 03:32:41"}
  • {"files"=>["https://ndownloader.figshare.com/files/1487044"], "description"=>"<p>Odds ratios (OR) of the five SNPs genotyped with their 95% lower (CL) and upper confidence limits (CU), χ<sup>2</sup>- and -log<sub>10</sub>P-values for genotypic, allelic and trend association considering 277 CHD-A German Shepherd Dogs as controls and 566 German Shepherd Dogs classified as CHD-C/D/E as cases.</p>", "links"=>[], "tags"=>["agriculture", "Animal management", "Computational biology", "genome analysis", "Genome-wide association studies", "Gene regulatory networks", "genetics", "Heredity", "Complex traits", "Animal genetics", "Genetics of disease", "Veterinary science", "Animal types", "Small animals", "Veterinary medicine", "Small animal care", "ratios", "snps", "genotyped", "limits", "allelic", "considering", "277", "chd-a", "german", "shepherd", "dogs", "controls", "566", "classified"], "article_id"=>1018077, "categories"=>["Biological Sciences"], "users"=>["Lena Fels", "Ottmar Distl"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0096618.t002", "stats"=>{"downloads"=>1, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratios_OR_of_the_five_SNPs_genotyped_with_their_95_lower_CL_and_upper_confidence_limits_CU_2_and_log_10_P_values_for_genotypic_allelic_and_trend_association_considering_277_CHD_A_German_Shepherd_Dogs_as_controls_and_566_German_Shepherd_Dogs_classifi/1018077", "title"=>"Odds ratios (OR) of the five SNPs genotyped with their 95% lower (CL) and upper confidence limits (CU), χ<sup>2</sup>- and -log<sub>10</sub>P-values for genotypic, allelic and trend association considering 277 CHD-A German Shepherd Dogs as controls and 566 German Shepherd Dogs classified as CHD-C/D/E as cases.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-05-06 03:32:41"}
  • {"files"=>["https://ndownloader.figshare.com/files/1487043"], "description"=>"<p>Odds ratios (OR) of the five SNPs genotyped with their 95% lower (CL) and upper confidence limits (CU), χ<sup>2</sup>- and -log<sub>10</sub>P-values for genotypic, allelic and trend association considering 277 CHD-A German Shepherd Dogs as controls and 65 German Shepherd Dogs classified as CHD-E as cases.</p>", "links"=>[], "tags"=>["agriculture", "Animal management", "Computational biology", "genome analysis", "Genome-wide association studies", "Gene regulatory networks", "genetics", "Heredity", "Complex traits", "Animal genetics", "Genetics of disease", "Veterinary science", "Animal types", "Small animals", "Veterinary medicine", "Small animal care", "ratios", "snps", "genotyped", "limits", "allelic", "considering", "277", "chd-a", "german", "shepherd", "dogs", "controls", "65", "classified", "chd-e"], "article_id"=>1018076, "categories"=>["Biological Sciences"], "users"=>["Lena Fels", "Ottmar Distl"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0096618.t005", "stats"=>{"downloads"=>1, "page_views"=>9, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratios_OR_of_the_five_SNPs_genotyped_with_their_95_lower_CL_and_upper_confidence_limits_CU_2_and_log_10_P_values_for_genotypic_allelic_and_trend_association_considering_277_CHD_A_German_Shepherd_Dogs_as_controls_and_65_German_Shepherd_Dogs_classifie/1018076", "title"=>"Odds ratios (OR) of the five SNPs genotyped with their 95% lower (CL) and upper confidence limits (CU), χ<sup>2</sup>- and -log<sub>10</sub>P-values for genotypic, allelic and trend association considering 277 CHD-A German Shepherd Dogs as controls and 65 German Shepherd Dogs classified as CHD-E as cases.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-05-06 03:32:41"}
  • {"files"=>["https://ndownloader.figshare.com/files/1487040"], "description"=>"<p>On the X-axis, the SNPs are given by dog chromosome number. The –log<sub>10</sub>P-values for each SNP genotype effect are plotted against the SNP position on each chromosome. Chromosomes are differentiated by colors. The color keys are given below the plot. The red line indicates a –log<sub>10</sub>P-value of 4.3 and the blue line indicates the threshold of the –log<sub>10</sub>P-values for genome-wide significance after correcting for multiple testing.</p>", "links"=>[], "tags"=>["agriculture", "Animal management", "Computational biology", "genome analysis", "Genome-wide association studies", "Gene regulatory networks", "genetics", "Heredity", "Complex traits", "Animal genetics", "Genetics of disease", "Veterinary science", "Animal types", "Small animals", "Veterinary medicine", "Small animal care", "genome-wide", "canine", "dysplasia", "german", "shepherd", "dogs", "linear"], "article_id"=>1018073, "categories"=>["Biological Sciences"], "users"=>["Lena Fels", "Ottmar Distl"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0096618.g001", "stats"=>{"downloads"=>1, "page_views"=>116, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Manhattan_plot_of_log_10_P_values_of_the_genome_wide_association_study_for_the_canine_hip_dysplasia_score_in_German_Shepherd_Dogs_using_a_mixed_linear_model_analysis_/1018073", "title"=>"Manhattan plot of –log<sub>10</sub>P-values of the genome-wide association study for the canine hip dysplasia score in German Shepherd Dogs using a mixed linear model analysis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-06 03:32:41"}
  • {"files"=>["https://ndownloader.figshare.com/files/1487046"], "description"=>"<p>SNP-IDs of the five SNPs genotyped in the validation set of 843 German Shepherd Dogs, their position on dog chromosome (CFA), their chromosomal position according to CanFam2.0, their minor alleles, their minor allele frequencies (MAF) in all dogs and among 277 unaffected dogs (CHD-grade A) and 566 affected dogs with 349 dogs classified as CHD-grade C, 152 dogs as CHD-grade D and 65 dogs as CHD-grade E.</p>", "links"=>[], "tags"=>["agriculture", "Animal management", "Computational biology", "genome analysis", "Genome-wide association studies", "Gene regulatory networks", "genetics", "Heredity", "Complex traits", "Animal genetics", "Genetics of disease", "Veterinary science", "Animal types", "Small animals", "Veterinary medicine", "Small animal care", "snps", "genotyped", "validation", "843", "german", "shepherd", "chromosome", "chromosomal", "allele", "frequencies", "dogs", "277", "unaffected", "566", "affected", "349", "classified", "chd-grade", "152", "65"], "article_id"=>1018079, "categories"=>["Biological Sciences"], "users"=>["Lena Fels", "Ottmar Distl"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0096618.t001", "stats"=>{"downloads"=>1, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_SNP_IDs_of_the_five_SNPs_genotyped_in_the_validation_set_of_843_German_Shepherd_Dogs_their_position_on_dog_chromosome_CFA_their_chromosomal_position_according_to_CanFam2_0_their_minor_alleles_their_minor_allele_frequencies_MAF_in_all_dogs_and_among_277_u/1018079", "title"=>"SNP-IDs of the five SNPs genotyped in the validation set of 843 German Shepherd Dogs, their position on dog chromosome (CFA), their chromosomal position according to CanFam2.0, their minor alleles, their minor allele frequencies (MAF) in all dogs and among 277 unaffected dogs (CHD-grade A) and 566 affected dogs with 349 dogs classified as CHD-grade C, 152 dogs as CHD-grade D and 65 dogs as CHD-grade E.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-05-06 03:32:41"}

PMC Usage Stats | Further Information

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