Ultraviolet B Irradiation Reduces the Expression of Adiponectin in Ovarial Adipose Tissues through Endocrine Actions of Calcitonin Gene-Related Peptide-Induced Serum Amyloid A
Events
Loading … Spinner

Mendeley | Further Information

{"title"=>"Ultraviolet B irradiation reduces the expression of adiponectin in ovarial adipose tissues through endocrine actions of calcitonin gene-related peptide-induced serum amyloid A", "type"=>"journal", "authors"=>[{"first_name"=>"Sho", "last_name"=>"Matsui", "scopus_author_id"=>"55754173000"}, {"first_name"=>"Takumi", "last_name"=>"Yamane", "scopus_author_id"=>"36515942200"}, {"first_name"=>"Kazuo", "last_name"=>"Kobayashi-Hattori", "scopus_author_id"=>"9632519200"}, {"first_name"=>"Yuichi", "last_name"=>"Oishi", "scopus_author_id"=>"7102516730"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"pmid"=>"24845824", "doi"=>"10.1371/journal.pone.0098040", "pui"=>"373160884", "issn"=>"19326203", "sgr"=>"84901369406", "scopus"=>"2-s2.0-84901369406"}, "id"=>"206484d5-a7e6-33fb-967a-61316c2595ff", "abstract"=>"Ultraviolet (UV) B irradiation decreases blood adiponectin levels, but the mechanism is not well understood. This study investigated how UVB irradiation reduces adiponectin expression in ovarial adipose tissues. Female Hos:HR-1 hairless mice were exposed to UVB (1.6 J/cm2) irradiation and were killed 24 h later. UVB irradiation decreased the adiponectin protein level in the serum and the adiponectin mRNA level in ovarial adipose tissues. UVB irradiation also decreased the mRNA levels of peroxisome proliferator-activated receptor (PPAR) ╬│, CCAAT/enhancer binding protein (C/EBP) ╬▒, C/EBP╬▓, and fatty acid binding protein 4 (aP2) in ovarial adipose tissues. In contrast, UVB irradiation increased the mRNA levels of interleukin (IL)-6 and monocyte chemoattractant protein (MCP)-1 in ovarial adipose tissues. In the serum and liver, the levels of serum amyloid A (SAA), involved in PPAR╬│, C/EBP╬▒, C/EBP╬▓, aP2, IL-6, and MCP-1 regulation, increased after UVB irradiation. The SAA gene is regulated by IL-1╬▓, IL-6, and tumor necrosis factor-╬▒, but only IL-6 expression increased in the liver after UVB irradiation. Additionally, in the liver, hypothalamus, and epidermis, UVB irradiation increased the expression of calcitonin gene-related peptide (CGRP), which upregulates SAA in the liver. Collectively, our results suggest that the CGRP signal induced by skin exposure to UVB transfers to the liver, possibly through the brain, and increases SAA production via IL-6 in the liver. In turn, serum SAA acts in an endocrine manner to decreases the serum adiponectin level by downregulating factors that regulate adiponectin expression in adipose tissues. ┬âŒ\u0090 2014 Matsui et al.", "link"=>"http://www.mendeley.com/research/ultraviolet-b-irradiation-reduces-expression-adiponectin-ovarial-adipose-tissues-through-endocrine-a", "reader_count"=>10, "reader_count_by_academic_status"=>{"Student > Doctoral Student"=>2, "Researcher"=>3, "Student > Ph. D. Student"=>2, "Other"=>2, "Unspecified"=>1}, "reader_count_by_user_role"=>{"Student > Doctoral Student"=>2, "Researcher"=>3, "Student > Ph. D. Student"=>2, "Other"=>2, "Unspecified"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>1, "Biochemistry, Genetics and Molecular Biology"=>2, "Agricultural and Biological Sciences"=>3, "Medicine and Dentistry"=>3, "Unspecified"=>1}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>3}, "Biochemistry, Genetics and Molecular Biology"=>{"Biochemistry, Genetics and Molecular Biology"=>2}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>0}

Scopus | Further Information

{"@_fa"=>"true", "link"=>[{"@_fa"=>"true", "@ref"=>"self", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84901369406"}, {"@_fa"=>"true", "@ref"=>"author-affiliation", "@href"=>"https://api.elsevier.com/content/abstract/scopus_id/84901369406?field=author,affiliation"}, {"@_fa"=>"true", "@ref"=>"scopus", "@href"=>"https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84901369406&origin=inward"}, {"@_fa"=>"true", "@ref"=>"scopus-citedby", "@href"=>"https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84901369406&origin=inward"}], "prism:url"=>"https://api.elsevier.com/content/abstract/scopus_id/84901369406", "dc:identifier"=>"SCOPUS_ID:84901369406", "eid"=>"2-s2.0-84901369406", "dc:title"=>"Ultraviolet B irradiation reduces the expression of adiponectin in ovarial adipose tissues through endocrine actions of calcitonin gene-related peptide-induced serum amyloid A", "dc:creator"=>"Matsui S.", "prism:publicationName"=>"PLoS ONE", "prism:eIssn"=>"19326203", "prism:volume"=>"9", "prism:issueIdentifier"=>"5", "prism:pageRange"=>nil, "prism:coverDate"=>"2014-05-20", "prism:coverDisplayDate"=>"20 May 2014", "prism:doi"=>"10.1371/journal.pone.0098040", "citedby-count"=>"8", "affiliation"=>[{"@_fa"=>"true", "affilname"=>"Tokyo University of Agriculture", "affiliation-city"=>"Tokyo", "affiliation-country"=>"Japan"}], "pubmed-id"=>"24845824", "prism:aggregationType"=>"Journal", "subtype"=>"ar", "subtypeDescription"=>"Article", "article-number"=>"e98040", "source-id"=>"10600153309", "openaccess"=>"1", "openaccessFlag"=>true}

Facebook

  • {"url"=>"http%3A%2F%2Fjournals.plos.org%2Fplosone%2Farticle%3Fid%3D10.1371%252Fjournal.pone.0098040", "share_count"=>0, "like_count"=>0, "comment_count"=>0, "click_count"=>0, "total_count"=>0}

Counter

  • {"month"=>"5", "year"=>"2014", "pdf_views"=>"21", "xml_views"=>"5", "html_views"=>"137"}
  • {"month"=>"6", "year"=>"2014", "pdf_views"=>"17", "xml_views"=>"1", "html_views"=>"83"}
  • {"month"=>"7", "year"=>"2014", "pdf_views"=>"15", "xml_views"=>"0", "html_views"=>"60"}
  • {"month"=>"8", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"2", "html_views"=>"31"}
  • {"month"=>"9", "year"=>"2014", "pdf_views"=>"8", "xml_views"=>"1", "html_views"=>"39"}
  • {"month"=>"10", "year"=>"2014", "pdf_views"=>"4", "xml_views"=>"2", "html_views"=>"33"}
  • {"month"=>"11", "year"=>"2014", "pdf_views"=>"3", "xml_views"=>"1", "html_views"=>"22"}
  • {"month"=>"12", "year"=>"2014", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"17"}
  • {"month"=>"1", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"2", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"3", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"4", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"40"}
  • {"month"=>"5", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"1", "html_views"=>"15"}
  • {"month"=>"6", "year"=>"2015", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"24"}
  • {"month"=>"7", "year"=>"2015", "pdf_views"=>"6", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"8", "year"=>"2015", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"28"}
  • {"month"=>"9", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"55"}
  • {"month"=>"10", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"24"}
  • {"month"=>"11", "year"=>"2015", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"15"}
  • {"month"=>"12", "year"=>"2015", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"1", "year"=>"2016", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"2", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"3", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"22"}
  • {"month"=>"4", "year"=>"2016", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"5", "year"=>"2016", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"6", "year"=>"2016", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"7", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"8", "year"=>"2016", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"9", "year"=>"2016", "pdf_views"=>"10", "xml_views"=>"0", "html_views"=>"16"}
  • {"month"=>"10", "year"=>"2016", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"10"}
  • {"month"=>"11", "year"=>"2016", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"19"}
  • {"month"=>"12", "year"=>"2016", "pdf_views"=>"11", "xml_views"=>"0", "html_views"=>"17"}
  • {"month"=>"1", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"21"}
  • {"month"=>"2", "year"=>"2017", "pdf_views"=>"7", "xml_views"=>"5", "html_views"=>"25"}
  • {"month"=>"3", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"4", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"18"}
  • {"month"=>"5", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"13"}
  • {"month"=>"6", "year"=>"2017", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"11"}
  • {"month"=>"7", "year"=>"2017", "pdf_views"=>"5", "xml_views"=>"1", "html_views"=>"22"}
  • {"month"=>"8", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"4"}
  • {"month"=>"9", "year"=>"2017", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"10"}
  • {"month"=>"10", "year"=>"2017", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"23"}
  • {"month"=>"11", "year"=>"2017", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"46"}
  • {"month"=>"12", "year"=>"2017", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"16"}
  • {"month"=>"1", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"10"}
  • {"month"=>"2", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"3", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"4", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"1", "html_views"=>"3"}
  • {"month"=>"5", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"6", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"7", "year"=>"2018", "pdf_views"=>"1", "xml_views"=>"3", "html_views"=>"2"}
  • {"month"=>"8", "year"=>"2018", "pdf_views"=>"2", "xml_views"=>"1", "html_views"=>"5"}
  • {"month"=>"9", "year"=>"2018", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"23"}
  • {"month"=>"10", "year"=>"2018", "pdf_views"=>"3", "xml_views"=>"2", "html_views"=>"6"}
  • {"month"=>"11", "year"=>"2018", "pdf_views"=>"0", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"12", "year"=>"2018", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"1", "year"=>"2019", "pdf_views"=>"2", "xml_views"=>"0", "html_views"=>"5"}
  • {"month"=>"2", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"3", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"2"}
  • {"month"=>"4", "year"=>"2019", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"5", "year"=>"2019", "pdf_views"=>"7", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"6", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"7", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"8"}
  • {"month"=>"8", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"7"}
  • {"month"=>"9", "year"=>"2019", "pdf_views"=>"1", "xml_views"=>"0", "html_views"=>"1"}
  • {"month"=>"10", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"11", "year"=>"2019", "pdf_views"=>"4", "xml_views"=>"0", "html_views"=>"6"}
  • {"month"=>"12", "year"=>"2019", "pdf_views"=>"5", "xml_views"=>"0", "html_views"=>"3"}
  • {"month"=>"1", "year"=>"2020", "pdf_views"=>"8", "xml_views"=>"0", "html_views"=>"4"}
  • {"month"=>"2", "year"=>"2020", "pdf_views"=>"4", "xml_views"=>"1", "html_views"=>"3"}
  • {"month"=>"3", "year"=>"2020", "pdf_views"=>"3", "xml_views"=>"0", "html_views"=>"1"}

Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1504393"], "description"=>"<p>PPARγ (A), C/EBPα (B), C/EBPβ (C), aP2 (D), IL-6 (E), and MCP-1 (E) mRNA levels in ovarial adipose tissues were measured by real-time PCR and expressed relative to the level of β-actin mRNA. Data represent the mean ±SE (n = 6). <sup>#</sup><i>p</i><0.05 or <sup># #</sup><i>p</i><0.01 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "mcp-1", "hairless"], "article_id"=>1032000, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g002", "stats"=>{"downloads"=>0, "page_views"=>15, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_PPAR_947_C_EBP_945_C_EBP_946_aP2_IL_6_and_MCP_1_expression_in_hairless_mice_/1032000", "title"=>"UVB irradiation PPARγ, C/EBPα, C/EBPβ, aP2, IL-6, and MCP-1 expression in hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504394"], "description"=>"<p>The level of SAA in the serum was measured by ELISA. Data represent the mean ±SE (n = 6). <sup># # #</sup><i>p</i><0.001 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "serum", "saa", "hairless"], "article_id"=>1032001, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g003", "stats"=>{"downloads"=>0, "page_views"=>50, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_increases_the_serum_SAA_level_in_hairless_mice_/1032001", "title"=>"UVB irradiation increases the serum SAA level in hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504396"], "description"=>"<p>SAA and adiponectin levels were measured as described in the <a href=\"http://www.plosone.org/article/info:doi/10.1371/journal.pone.0098040#s2\" target=\"_blank\">Materials and Methods</a> section. The correlation between the levels of SAA protein in the serum and adiponectin mRNA in ovarial adipose tissues or between the levels of SAA and adiponectin in the serum was evaluated by Pearson's product-moment correlation coefficient using individual data from 6 mice per UVB (−) and UVB (+) group.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "saa", "adiponectin"], "article_id"=>1032003, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g004", "stats"=>{"downloads"=>1, "page_views"=>13, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Correlation_between_SAA_and_adiponectin_levels_/1032003", "title"=>"Correlation between SAA and adiponectin levels.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504397"], "description"=>"<p>The level of SAA mRNA in the liver (A) was measured by real-time PCR and expressed relative to that of β-actin mRNA. The level of SAA protein in the liver (B) was measured by ELISA. <sup># # #</sup><i>p</i><0.001 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "saa", "hairless"], "article_id"=>1032005, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g005", "stats"=>{"downloads"=>2, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_increases_liver_SAA_expression_in_hairless_mice_/1032005", "title"=>"UVB irradiation increases liver SAA expression in hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504399"], "description"=>"<p>The levels of TNFα (A), IL-1β (B), and IL-6 (C) mRNA in the liver were determined by real-time PCR and expressed relative to the level of β-actin mRNA. The level of IL-6 protein in the liver was measured by ELISA (D). Data represent the mean ±SE (n = 6). <sup>#</sup><i>p</i><0.05 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "il-6", "hairless"], "article_id"=>1032006, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g006", "stats"=>{"downloads"=>2, "page_views"=>17, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_on_liver_TNF_945_IL_1_946_and_IL_6_expression_in_hairless_mice_/1032006", "title"=>"UVB irradiation on liver TNFα, IL-1β, and IL-6 expression in hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504401"], "description"=>"<p>The level of CGRP mRNA in the liver (A) was measured by real-time PCR and expressed relative to that of β-actin mRNA. The level of CGRP protein in the liver (B) was measured by ELISA. <sup>#</sup><i>p</i><0.05 or <sup>##</sup><i>p</i><0.01 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "cgrp", "hairless"], "article_id"=>1032008, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g007", "stats"=>{"downloads"=>2, "page_views"=>45, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_increases_CGRP_expression_in_the_liver_of_hairless_mice_/1032008", "title"=>"UVB irradiation increases CGRP expression in the liver of hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504402"], "description"=>"<p>The level of CGRP mRNA in the hypothalamus (A) was determined by real-time PCR and expressed relative to that of β-actin mRNA. The level of CGRP protein in the hypothalamus (B) was measured by ELISA. Data represent the mean ±SE (n = 6). <sup>#</sup><i>p</i><0.05 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "cgrp", "hypothalamus", "hairless"], "article_id"=>1032009, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g008", "stats"=>{"downloads"=>3, "page_views"=>23, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_increases_CGRP_expression_in_the_hypothalamus_of_hairless_mice_/1032009", "title"=>"UVB irradiation increases CGRP expression in the hypothalamus of hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504404"], "description"=>"<p>The levels of CGRP mRNA in the epidermis (A) and eye (B) were measured by real-time PCR and expressed relative to the level of β-actin mRNA. The level of CGRP in the serum (C) was measured by ELISA. Data represent the mean ±SE (n = 6). <sup>##</sup><i>p</i><0.01 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "serum", "uvb-irradiated", "hairless"], "article_id"=>1032011, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g009", "stats"=>{"downloads"=>1, "page_views"=>21, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_CGRP_expression_in_the_epidermis_eye_and_serum_of_UVB_irradiated_hairless_mice_/1032011", "title"=>"CGRP expression in the epidermis, eye, and serum of UVB-irradiated hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504405"], "description"=>"<p>The CGRP signal induced by exposure of the skin to UVB can transfer to the brain and then to the liver, possibly via a neural pathway. Increased CGRP in the liver induces the expression and secretion of SAA via the action of IL-6. In an endocrine manner, SAA in the serum downregulates PPARγ, C/EBPα, C/EBPβ, and aP2 mRNA levels and upregulates IL-6 and MCP-1 mRNA levels in the ovarial adipose tissues. The downregulation of adiponectin expression in the adipose tissues by these factors contributes to the decrease in serum adiponectin. Reduced levels of adiponectin in the serum may impair skin function (Yamane <i>et al</i>. 2010). Thus, the decrease in adiponectin induced by UVB irradiation can have adverse effects on skin function.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "mechanisms", "uvb-induced", "adiponectin", "ovarial", "adipose"], "article_id"=>1032012, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g010", "stats"=>{"downloads"=>1, "page_views"=>19, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Putative_mechanisms_for_the_UVB_induced_decrease_in_adiponectin_expression_in_ovarial_adipose_tissues_/1032012", "title"=>"Putative mechanisms for the UVB-induced decrease in adiponectin expression in ovarial adipose tissues.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}
  • {"files"=>["https://ndownloader.figshare.com/files/1504392"], "description"=>"<p>The level of adiponectin in the serum (A) was measured by ELISA. The level of adiponectin mRNA in ovarial adipose tissues was determined by real-time PCR, and expressed relative to that of β-actin mRNA. Data represent the mean ±SE (n = 6). <sup>#</sup><i>p</i><0.05 indicates values that are significantly different from the UVB (−) group. UVB (−), non-UVB-irradiated mice; UVB (+), UVB-irradiated mice.</p>", "links"=>[], "tags"=>["Biochemistry", "lipids", "Lipid metabolism", "hormones", "cell biology", "Signal transduction", "cell signaling", "Molecular cell biology", "genetics", "gene expression", "immunology", "Immune response", "inflammation", "immunity", "physics", "Electromagnetic radiation", "light", "Ultraviolet radiation", "Ultraviolet b", "irradiation", "decreases", "adiponectin", "serum", "adipose", "tissues", "hairless"], "article_id"=>1031999, "categories"=>["Biological Sciences"], "users"=>["Sho Matsui", "Takumi Yamane", "Kazuo Kobayashi-Hattori", "Yuichi Oishi"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0098040.g001", "stats"=>{"downloads"=>0, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_UVB_irradiation_decreases_adiponectin_levels_in_the_serum_and_adipose_tissues_of_hairless_mice_/1031999", "title"=>"UVB irradiation decreases adiponectin levels in the serum and adipose tissues of hairless mice.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-05-20 03:08:16"}

PMC Usage Stats | Further Information

  • {"unique-ip"=>"7", "full-text"=>"5", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"5"}
  • {"unique-ip"=>"18", "full-text"=>"18", "pdf"=>"10", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"6"}
  • {"unique-ip"=>"13", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"4"}
  • {"unique-ip"=>"11", "full-text"=>"19", "pdf"=>"9", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"5"}
  • {"unique-ip"=>"15", "full-text"=>"19", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"6"}
  • {"unique-ip"=>"8", "full-text"=>"10", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"3"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"2"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"8"}
  • {"unique-ip"=>"11", "full-text"=>"10", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"9"}
  • {"unique-ip"=>"10", "full-text"=>"9", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"10"}
  • {"unique-ip"=>"11", "full-text"=>"19", "pdf"=>"12", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"7"}
  • {"unique-ip"=>"7", "full-text"=>"11", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"8"}
  • {"unique-ip"=>"9", "full-text"=>"7", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"9"}
  • {"unique-ip"=>"15", "full-text"=>"13", "pdf"=>"7", "abstract"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"6", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"2"}
  • {"unique-ip"=>"12", "full-text"=>"12", "pdf"=>"5", "abstract"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"6", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2014", "month"=>"12"}
  • {"unique-ip"=>"10", "full-text"=>"7", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"1"}
  • {"unique-ip"=>"14", "full-text"=>"9", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2015", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"19", "pdf"=>"7", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2015", "month"=>"12"}
  • {"unique-ip"=>"10", "full-text"=>"13", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"1"}
  • {"unique-ip"=>"11", "full-text"=>"11", "pdf"=>"8", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"3"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"4"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"5"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"4", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"6"}
  • {"unique-ip"=>"2", "full-text"=>"1", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"7"}
  • {"unique-ip"=>"8", "full-text"=>"9", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"8"}
  • {"unique-ip"=>"8", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"9"}
  • {"unique-ip"=>"11", "full-text"=>"12", "pdf"=>"5", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"10"}
  • {"unique-ip"=>"6", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"11"}
  • {"unique-ip"=>"3", "full-text"=>"3", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2016", "month"=>"12"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"1"}
  • {"unique-ip"=>"6", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"2"}
  • {"unique-ip"=>"4", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"3"}
  • {"unique-ip"=>"4", "full-text"=>"4", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"4"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"3", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"5"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"6"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"7"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"3", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"8"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"6", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"9"}
  • {"unique-ip"=>"6", "full-text"=>"6", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"11"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2017", "month"=>"12"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"1"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"1", "abstract"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"3"}
  • {"unique-ip"=>"13", "full-text"=>"8", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"1"}
  • {"unique-ip"=>"5", "full-text"=>"4", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"4"}
  • {"unique-ip"=>"6", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"13", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"5"}
  • {"unique-ip"=>"5", "full-text"=>"6", "pdf"=>"3", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"6"}
  • {"unique-ip"=>"9", "full-text"=>"9", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"1", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"7"}
  • {"unique-ip"=>"13", "full-text"=>"8", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"7", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"11"}
  • {"unique-ip"=>"12", "full-text"=>"8", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"10"}
  • {"unique-ip"=>"8", "full-text"=>"8", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"8"}
  • {"unique-ip"=>"16", "full-text"=>"11", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"10", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"9"}
  • {"unique-ip"=>"23", "full-text"=>"22", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"2", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2018", "month"=>"12"}
  • {"unique-ip"=>"8", "full-text"=>"7", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"4", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"2"}
  • {"unique-ip"=>"5", "full-text"=>"5", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"5", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"3"}
  • {"unique-ip"=>"2", "full-text"=>"2", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"4"}
  • {"unique-ip"=>"4", "full-text"=>"17", "pdf"=>"0", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"40", "supp-data"=>"0", "cited-by"=>"2", "year"=>"2019", "month"=>"5"}
  • {"unique-ip"=>"11", "full-text"=>"5", "pdf"=>"1", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"8", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"8"}
  • {"unique-ip"=>"7", "full-text"=>"6", "pdf"=>"2", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"9"}
  • {"unique-ip"=>"10", "full-text"=>"8", "pdf"=>"4", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"10"}
  • {"unique-ip"=>"6", "full-text"=>"2", "pdf"=>"5", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2019", "month"=>"12"}
  • {"unique-ip"=>"6", "full-text"=>"14", "pdf"=>"6", "scanned-summary"=>"0", "scanned-page-browse"=>"0", "figure"=>"0", "supp-data"=>"0", "cited-by"=>"0", "year"=>"2020", "month"=>"2"}

Relative Metric

{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Biology and life sciences/Biochemistry", "average_usage"=>[282]}, {"subject_area"=>"/Biology and life sciences/Physiology", "average_usage"=>[280]}, {"subject_area"=>"/Medicine and health sciences/Physiology", "average_usage"=>[278]}, {"subject_area"=>"/Physical sciences", "average_usage"=>[271]}, {"subject_area"=>"/Physical sciences/Physics", "average_usage"=>[266]}]}
Loading … Spinner
There are currently no alerts