Relationships between 25-Hydroxyvitamin D and Nocturnal Enuresis in Five- to Seven-Year-Old Children
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{"title"=>"Relationships between 25-hydroxyvitamin D and nocturnal enuresis in five- to seven-year-old children", "type"=>"journal", "authors"=>[{"first_name"=>"Luanluan", "last_name"=>"Li", "scopus_author_id"=>"55673695800"}, {"first_name"=>"Huafei", "last_name"=>"Zhou", "scopus_author_id"=>"56208763500"}, {"first_name"=>"Xin", "last_name"=>"Yang", "scopus_author_id"=>"55674399200"}, {"first_name"=>"Li", "last_name"=>"Zhao", "scopus_author_id"=>"57199019017"}, {"first_name"=>"Xiaodan", "last_name"=>"Yu", "scopus_author_id"=>"55673878300"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"scopus"=>"2-s2.0-84902578499", "pmid"=>"24911026", "sgr"=>"84902578499", "doi"=>"10.1371/journal.pone.0099316", "issn"=>"19326203", "pui"=>"373338042"}, "id"=>"3b6631a3-fd48-3893-86b4-37a6569d221e", "abstract"=>"BACKGROUND: Vitamin D has been recognized to contribute to various physiological processes. However, no study has investigated serum 25-hydroxyvitamin D [25(OH)D] concentrations in children with nocturnal enuresis (NE) in the English literature.\\n\\nOBJECTIVE: In the present study, serum 25(OH)D concentrations were measured in five- to seven-year-old children with NE and compared with those in non-enuretic children to investigate whether there was any relationship between 25(OH)D and NE as the first time in the literature.\\n\\nDESIGN: Two hundred forty-seven five- to seven-year-old children were recruited from Taizhou, Zhejiang Province, China. Serum 25(OH)D concentrations were measured, and the structured questionnaire was administered to the parents of all children. Low 25(OH)D was defined as serum 25(OH)D concentrations below 20 ng/ml.\\n\\nRESULTS: The prevalence of NE was 7.3% in the group of children with 25(OH)D concentrations that exceeded 20 ng/ml; this prevalence was much lower than the 17.5% observed in the group of children with 25(OH)D concentrations below 20 ng/ml (p<0.05). After adjusting for potential confounders, serum 25(OH)D (≥20 ng/ml) was significantly associated with NE and represented a protective factor against NE (OR = 0.31, 95%CI = 0.092, 1.0, P<0.05). A nonlinear relationship between 25(OH)D and NE was observed. The prevalence of NE decreased with increasing 25(OH)D concentrations above 19 ng/ml. Additionally, children exhibiting higher frequencies of bedwetting had lower 25(OH)D concentrations [5-7 times/week: 18.3±4.8; 2-4 times/week: 20.9±4.1; 0-1 times/week: 23.6±6.4 (ng/ml), P<0.05)].\\n\\nCONCLUSIONS: Low 25(OH)D was associated with an increased risk of NE in children aged five to seven years.", "link"=>"http://www.mendeley.com/research/relationships-between-25hydroxyvitamin-d-nocturnal-enuresis-five-sevenyearold-children", "reader_count"=>9, "reader_count_by_academic_status"=>{"Unspecified"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>2, "Student > Master"=>1, "Other"=>2, "Professor"=>1}, "reader_count_by_user_role"=>{"Unspecified"=>1, "Researcher"=>1, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>2, "Student > Master"=>1, "Other"=>2, "Professor"=>1}, "reader_count_by_subject_area"=>{"Unspecified"=>1, "Nursing and Health Professions"=>1, "Medicine and Dentistry"=>5, "Agricultural and Biological Sciences"=>1, "Pharmacology, Toxicology and Pharmaceutical Science"=>1}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>5}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>1}, "Nursing and Health Professions"=>{"Nursing and Health Professions"=>1}, "Unspecified"=>{"Unspecified"=>1}, "Pharmacology, Toxicology and Pharmaceutical Science"=>{"Pharmacology, Toxicology and Pharmaceutical Science"=>1}}, "group_count"=>1}

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1527535"], "description"=>"<p>25(OH)D, 25-hydroxyvitamin D.</p><p><b>*</b>Determined by univariate analysis.</p>", "links"=>[], "tags"=>["nutrition", "diet", "malnutrition", "nutrients", "Nutritional deficiencies", "Nutritional diseases", "Nutritional disorders", "epidemiology", "Environmental epidemiology", "Pediatric epidemiology", "pediatrics", "Child development", "Child health", "urology", "Pediatric urology", "nocturnal", "enuresis"], "article_id"=>1051464, "categories"=>["Biological Sciences"], "users"=>["LuanLuan Li", "Huafei Zhou", "Xin Yang", "Li Zhao", "XiaoDan Yu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0099316.t001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Effects_of_risk_factors_on_nocturnal_enuresis_n_247_/1051464", "title"=>"Effects of risk factors on nocturnal enuresis (n = 247).<sup>*</sup>", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-06-09 03:43:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/1527536"], "description"=>"<p>β, regression coefficient; 25(OH)D, 25-hydroxyvitamin D.</p><p><b>*</b>Unadjusted and analyzed by using liner regression.</p>#<p>Adjusted for gender, age, gestational age, birth weight, maternal education, paternal education, and family income by using multiple linear regression.</p>†<p>Unadjusted β, 0.94; adjusted β, 0.9.</p>‡<p>Unadjusted OR, 0.52; adjusted OR, 0.31.</p>", "links"=>[], "tags"=>["nutrition", "diet", "malnutrition", "nutrients", "Nutritional deficiencies", "Nutritional diseases", "Nutritional disorders", "epidemiology", "Environmental epidemiology", "Pediatric epidemiology", "pediatrics", "Child development", "Child health", "urology", "Pediatric urology", "nocturnal"], "article_id"=>1051465, "categories"=>["Biological Sciences"], "users"=>["LuanLuan Li", "Huafei Zhou", "Xin Yang", "Li Zhao", "XiaoDan Yu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0099316.t002", "stats"=>{"downloads"=>2, "page_views"=>10, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Adjusted_effect_of_25_OH_D_on_nocturnal_enuresis_/1051465", "title"=>"Adjusted effect of 25(OH)D on nocturnal enuresis.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-06-09 03:43:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/1527537"], "description"=>"<p>25(OH)D, 25-hydroxyvitamin D.</p><p><b>*</b>Adjusted for gender, age, gestational age, birth weight, maternal education, paternal education, and family income by using piece-wise linear regression.</p>", "links"=>[], "tags"=>["nutrition", "diet", "malnutrition", "nutrients", "Nutritional deficiencies", "Nutritional diseases", "Nutritional disorders", "epidemiology", "Environmental epidemiology", "Pediatric epidemiology", "pediatrics", "Child development", "Child health", "urology", "Pediatric urology", "nocturnal"], "article_id"=>1051466, "categories"=>["Biological Sciences"], "users"=>["LuanLuan Li", "Huafei Zhou", "Xin Yang", "Li Zhao", "XiaoDan Yu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0099316.t003", "stats"=>{"downloads"=>1, "page_views"=>6, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Threshold_effect_analysis_of_25_OH_D_on_nocturnal_enuresis_/1051466", "title"=>"Threshold effect analysis of 25(OH)D on nocturnal enuresis.<sup>*</sup>", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-06-09 03:43:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/1527533"], "description"=>"<p>A nonlinear relationship between serum 25(OH)D concentrations and nocturnal enuresis was observed after adjusting for gender, age, gestational age, birth weight, maternal education, paternal education, and family income. A threshold for 25(OH)D of 19 ng/ml existed for nocturnal enuresis. 25(OH)D, 25-hydroxyvitamin D.</p>", "links"=>[], "tags"=>["nutrition", "diet", "malnutrition", "nutrients", "Nutritional deficiencies", "Nutritional diseases", "Nutritional disorders", "epidemiology", "Environmental epidemiology", "Pediatric epidemiology", "pediatrics", "Child development", "Child health", "urology", "Pediatric urology", "nocturnal"], "article_id"=>1051462, "categories"=>["Biological Sciences"], "users"=>["LuanLuan Li", "Huafei Zhou", "Xin Yang", "Li Zhao", "XiaoDan Yu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0099316.g001", "stats"=>{"downloads"=>0, "page_views"=>5, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_Relationship_between_25_OH_D_and_nocturnal_enuresis_/1051462", "title"=>"The Relationship between 25(OH)D and nocturnal enuresis.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-06-09 03:43:26"}
  • {"files"=>["https://ndownloader.figshare.com/files/1527534"], "description"=>"<p>Serum 25(OH)D concentrations (mean ± SD): 5–7 times/week: 18.3±4.8(ng/ml); 2–4 times/week: 20.9±4.1(ng/ml); 0–1 times/week: 23.6±6.4 (ng/ml). Compared to the 5–7 times/week and 2–4 times/week groups, the concentrations of 25(OH)D in the 0–1 times/week group were much higher (P<0.05). 25(OH)D, 25-hydroxyvitamin D.</p>", "links"=>[], "tags"=>["nutrition", "diet", "malnutrition", "nutrients", "Nutritional deficiencies", "Nutritional diseases", "Nutritional disorders", "epidemiology", "Environmental epidemiology", "Pediatric epidemiology", "pediatrics", "Child development", "Child health", "urology", "Pediatric urology"], "article_id"=>1051463, "categories"=>["Biological Sciences"], "users"=>["LuanLuan Li", "Huafei Zhou", "Xin Yang", "Li Zhao", "XiaoDan Yu"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0099316.g002", "stats"=>{"downloads"=>7, "page_views"=>11, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_The_effect_of_25_OH_D_on_the_frequency_of_bedwetting_/1051463", "title"=>"The effect of 25(OH)D on the frequency of bedwetting.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-06-09 03:43:26"}

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