Relationship of Glycated Hemoglobin Levels with Myocardial Injury following Elective Percutaneous Coronary Intervention in Patients with Type 2 Diabetes Mellitus
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Mendeley | Further Information

{"title"=>"Relationship of glycated hemoglobin levels with myocardial injury following elective percutaneous coronary intervention in patients with type 2 diabetes mellitus.", "type"=>"journal", "authors"=>[{"first_name"=>"Xiao-Lin", "last_name"=>"Li"}, {"first_name"=>"Jian-Jun", "last_name"=>"Li"}, {"first_name"=>"Yuan-Lin", "last_name"=>"Guo"}, {"first_name"=>"Cheng-Gang", "last_name"=>"Zhu"}, {"first_name"=>"Rui-Xia", "last_name"=>"Xu"}, {"first_name"=>"Sha", "last_name"=>"Li"}, {"first_name"=>"Ping", "last_name"=>"Qing"}, {"first_name"=>"Na-Qiong", "last_name"=>"Wu"}, {"first_name"=>"Li-Xin", "last_name"=>"Jiang"}, {"first_name"=>"Bo", "last_name"=>"Xu"}, {"first_name"=>"Run-Lin", "last_name"=>"Gao"}], "year"=>2014, "source"=>"PloS one", "identifiers"=>{"issn"=>"1932-6203 (Electronic)", "pmid"=>"24988213", "doi"=>"10.1371/journal.pone.0101719"}, "keywords"=>["Aged", "Cardiomyopathies", "Diabetes Mellitus, Type 2", "Female", "Hemoglobin A, Glycosylated", "Humans", "Male", "Middle Aged", "Percutaneous Coronary Intervention", "Risk Factors", "Troponin I", "adverse effects", "analysis", "blood", "complications", "etiology"], "id"=>"6ddb6e24-df05-3aff-abe8-452815debfed", "abstract"=>"BACKGROUND: Glycated hemoglobin (HbA1c) predicts clinical cardiovascular disease or cardiovascular mortality. However, the relationship between HbA1c and myocardial injury following elective percutaneous coronary intervention (PCI) in patients with type 2 diabetes mellitus (DM) has not been investigated. OBJECTIVES: The study sought to assess the relationship between HbA1c and myocardial injury following elective PCI in patients with type 2 DM. METHODS: We studied a cohort of consecutive 994 diabetic patients with coronary artery disease (CAD) undergoing elective PCI. Periprocedural myocardial injury was evaluated by analysis of troponin I (cTnI). The association between preprocedural HbA1c levels and the peak values of cTnI within 24 hours after PCI was evaluated. RESULTS: Peak postprocedural cTnI > 1xupper limit of normal (ULN), >3xULN and >5xULN were detected in 543 (54.6%), 337 (33.9%) and 245 (24.6%) respectively. In the multivariate model, higher HbA1c levels were associated with less risk of postprocedural cTnI >1xULN (odds ratio [OR], 0.85; 95% confidence interval [CI], 0.76-0.95; P = 0.005). There was a trend that higher HbA1c levels were associated with less risk of postprocedural cTnI >3xULN (OR, 0.90; 95% CI, 0.81-1.02; P = 0.088). HbA1c was not associated with the risk of postprocedural cTnI elevation above 5xULN (OR, 0.95; 95% CI, 0.84-1.08; P = 0.411). CONCLUSIONS: The present study provided the first line of evidence that higher preprocedural HbA1c levels were associated with less risk of myocardial injury following elective PCI in diabetic patients.", "link"=>"http://www.mendeley.com/research/relationship-glycated-hemoglobin-levels-myocardial-injury-following-elective-percutaneous-coronary-i-2", "reader_count"=>3, "reader_count_by_academic_status"=>{"Professor > Associate Professor"=>1, "Student > Master"=>1, "Student > Bachelor"=>1}, "reader_count_by_user_role"=>{"Professor > Associate Professor"=>1, "Student > Master"=>1, "Student > Bachelor"=>1}, "reader_count_by_subject_area"=>{"Medicine and Dentistry"=>3}, "reader_count_by_subdiscipline"=>{"Medicine and Dentistry"=>{"Medicine and Dentistry"=>3}}, "group_count"=>0}

Scopus | Further Information

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Figshare

  • {"files"=>["https://ndownloader.figshare.com/files/1578184"], "description"=>"<p>HbA1c  = glycated hemoglobin; cTnI  =  cardiac troponin I; OR  =  odds ratio; ULN  =  upper limit of normal; MI  =  myocardial infarcton; NT-proBNP  =  N-terminal pro-brain natriuretic peptide.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "postprocedural", "ctni", "elevation"], "article_id"=>1091876, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.g001", "stats"=>{"downloads"=>2, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratio_for_postprocedural_cTnI_elevation_above_1_215_ULN_/1091876", "title"=>"Odds ratio for postprocedural cTnI elevation above 1×ULN.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578187"], "description"=>"<p>HbA1c  = glycated hemoglobin; cTnI  =  cardiac troponin I; OR  =  odds ratio; ULN  =  upper limit of normal; MI  =  myocardial infarcton; NT-proBNP  =  N-terminal pro-brain natriuretic peptide.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "postprocedural", "ctni", "elevation"], "article_id"=>1091878, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.g002", "stats"=>{"downloads"=>1, "page_views"=>3, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratio_for_postprocedural_cTnI_elevation_above_3_215_ULN_/1091878", "title"=>"Odds ratio for postprocedural cTnI elevation above 3×ULN.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578194"], "description"=>"<p>HbA1c  = glycated hemoglobin; cTnI  =  cardiac troponin I; OR  =  odds ratio; ULN  =  upper limit of normal; MI  =  myocardial infarcton; NT-proBNP  =  N-terminal pro-brain natriuretic peptide.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "postprocedural", "ctni", "elevation"], "article_id"=>1091879, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.g003", "stats"=>{"downloads"=>0, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratio_for_postprocedural_cTnI_elevation_above_5_215_ULN_/1091879", "title"=>"Odds ratio for postprocedural cTnI elevation above 5×ULN.", "pos_in_sequence"=>0, "defined_type"=>1, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578195"], "description"=>"<p>MI  =  myocardial infarcton; PCI  =  percutaneous coronary intervention; CABG  =  coronary artery bypass graft; CAD  =  coronary artery disease; LDL-C  =  low-density lipoprotein cholesterol; HDL-C  =  high-density lipoprotein cholesterol; hs-CRP  =  high-sensitivity C-reactive protein; NT-proBNP  =  N-terminal pro-brain natriuretic peptide; cTnI, cardiac troponin I.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "postprocedural", "ctni"], "article_id"=>1091880, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t003", "stats"=>{"downloads"=>6, "page_views"=>7, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Analysis_of_factors_related_to_postprocedural_cTnI_levels_log_transformed_/1091880", "title"=>"Analysis of factors related to postprocedural cTnI levels (log-transformed).", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578197"], "description"=>"<p>Values are expressed as n (%), mean ± SD or median with interquartile range.</p><p>HbA1c  = glycated hemoglobin; LM  =  left main; LAD  =  left anterior descending; LCX  =  left circumflex; RCA  =  right coronary artery; LMWH  =  low molecular weight heparin; GPI  =  glycoprotein inhibitors.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction"], "article_id"=>1091882, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t002", "stats"=>{"downloads"=>0, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Procedural_characteristics_/1091882", "title"=>"Procedural characteristics.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578198"], "description"=>"<p>Values are expressed as mean ± SD, median with interquartile range or n (%).</p><p>LDL-C  =  low-density lipoprotein cholesterol; MI  =  myocardial infarcton; PCI  =  percutaneous coronary intervention; CABG  =  coronary artery bypass graft; CAD  =  coronary artery disease; HDL-C  =  high-density lipoprotein cholesterol; hs-CRP  =  high-sensitivity C-reactive protein; NT-proBNP  =  N-terminal pro-brain natriuretic peptide; cTnI  =  cardiac troponin I; CCBs  =  calcium channel blockers; ACE  =  angiotensin-converting enzyme; ARBs  =  angiotensin receptor blockers.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction"], "article_id"=>1091883, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t001", "stats"=>{"downloads"=>1, "page_views"=>4, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Baseline_clinical_characteristics_/1091883", "title"=>"Baseline clinical characteristics.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578199"], "description"=>"<p>HbA1c  = glycated hemoglobin; cTnI  =  cardiac troponin I; OR  =  odds ratio; ULN  =  upper limit of normal; MI  =  myocardial infarcton; NT-proBNP  =  N-terminal pro-brain natriuretic peptide.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "adjusted", "periprocedural", "myocardial", "quartiles"], "article_id"=>1091885, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t006", "stats"=>{"downloads"=>1, "page_views"=>1, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Unadjusted_and_adjusted_OR_for_periprocedural_myocardial_injury_according_to_quartiles_of_HbA1c_/1091885", "title"=>"Unadjusted and adjusted OR for periprocedural myocardial injury according to quartiles of HbA1c.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578201"], "description"=>"<p>Values were expressed as median with interquartile ranges or n (%). The analyses were adjusted for age, prior myocardial infarction, NT-proBNP, preprocedural cTnI, number of target vessels and total stent length.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "post-pci", "cardiac", "troponin"], "article_id"=>1091886, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t005", "stats"=>{"downloads"=>1, "page_views"=>2, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Distribution_of_post_PCI_cardiac_troponin_I_/1091886", "title"=>"Distribution of post-PCI cardiac troponin I.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}
  • {"files"=>["https://ndownloader.figshare.com/files/1578203"], "description"=>"<p>HbA1c  = glycated hemoglobin; cTnI  =  cardiac troponin I; OR  =  odds ratio; ULN  =  upper limit of normal; MI  =  myocardial infarcton; NT-proBNP  =  N-terminal pro-brain natriuretic peptide.</p>", "links"=>[], "tags"=>["Vascular medicine", "Coronary artery disease", "cardiology", "Interventional cardiology", "Myocardial infarction", "postprocedural", "ctni", "elevation", "increment"], "article_id"=>1091888, "categories"=>["Biological Sciences"], "users"=>["Xiao-Lin Li", "Jian-jun Li", "Yuan-Lin Guo", "Cheng-Gang Zhu", "Rui-Xia Xu", "Sha Li", "Ping Qing", "Na-Qiong Wu", "Li-Xin Jiang", "Bo Xu", "Run-Lin Gao"], "doi"=>"https://dx.doi.org/10.1371/journal.pone.0101719.t004", "stats"=>{"downloads"=>1, "page_views"=>8, "likes"=>0}, "figshare_url"=>"https://figshare.com/articles/_Odds_ratio_for_postprocedural_cTnI_elevation_associated_with_1_increment_in_the_HbA1c_/1091888", "title"=>"Odds ratio for postprocedural cTnI elevation associated with 1% increment in the HbA1c.", "pos_in_sequence"=>0, "defined_type"=>3, "published_date"=>"2014-07-02 03:03:58"}

PMC Usage Stats | Further Information

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Relative Metric

{"start_date"=>"2014-01-01T00:00:00Z", "end_date"=>"2014-12-31T00:00:00Z", "subject_areas"=>[{"subject_area"=>"/Medicine and health sciences/Cardiology", "average_usage"=>[246]}, {"subject_area"=>"/Medicine and health sciences/Vascular medicine", "average_usage"=>[248]}]}
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