Risk of Developing Depressive Disorders following Rheumatoid Arthritis: A Nationwide Population-Based Study
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Mendeley | Further Information

{"title"=>"Risk of developing depressive disorders following rheumatoid arthritis: a nationwide population-based study.", "type"=>"journal", "authors"=>[{"first_name"=>"Shu-Li", "last_name"=>"Wang"}, {"first_name"=>"Cheng-Ho", "last_name"=>"Chang"}, {"first_name"=>"Li-Yu", "last_name"=>"Hu"}, {"first_name"=>"Shih-Jen", "last_name"=>"Tsai"}, {"first_name"=>"Albert C", "last_name"=>"Yang"}, {"first_name"=>"Zi-Hong", "last_name"=>"You"}], "year"=>2014, "source"=>"PLoS ONE", "identifiers"=>{"issn"=>"1932-6203", "doi"=>"10.1371/journal.pone.0107791", "pmid"=>"25226167"}, "id"=>"92f135b5-87a7-31e9-a915-9ef42bcc5501", "abstract"=>"BACKGROUND & AIMS:To evaluate the risk of depressive disorders among rheumatoid arthritis (RA) by using the Taiwan National Health Insurance Research Database (NHIRD).\\n\\nMETHODS:We conducted a retrospective study of a matched cohort of 18 285 participants (3 657 RA patients and 14 628 control patients) who were selected from the NHIRD. Patients were observed for a maximum of 10 years to determine the rates of newly diagnosed depressive disorders, and Cox regression was used to identify the risk factors associated with depressive disorders in RA patients.\\n\\nRESULTS:During the 10-year follow-up period, 205 (11.2 per 1000 person-years) RA patients and 384 (5.1 per 1000 person-years) control patients were diagnosed with depressive disorders. In RA patients, most depressive disorders (n = 163, 80%) developed with five years of being diagnosed with RA. The incidence risk ratio of depressive disorders between RA patients and control patients was 2.20 (95% confidence interval [CI], 1.84-2.61, P<.001). After adjusting for age, sex, and comorbidities, RA patients were 2.06 times more likely to develop depressive disorders (95% CI, 1.73-2.44, P<.001) compared with the control patients. Hyperthyroidism (HR = 1.67) was an independent risk factor for depressive disorders in patients with RA.\\n\\nCONCLUSIONS:The likelihood of developing depressive disorders is greater among RA patients than among patients without RA. Symptoms of depression should be sought in patients with RA.", "link"=>"http://www.mendeley.com/research/risk-developing-depressive-disorders-following-rheumatoid-arthritis-nationwide-populationbased-study", "reader_count"=>21, "reader_count_by_academic_status"=>{"Student > Doctoral Student"=>1, "Researcher"=>4, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>3, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_user_role"=>{"Student > Doctoral Student"=>1, "Researcher"=>4, "Student > Ph. D. Student"=>1, "Student > Postgraduate"=>3, "Student > Master"=>8, "Other"=>2, "Student > Bachelor"=>1, "Professor"=>1}, "reader_count_by_subject_area"=>{"Engineering"=>1, "Unspecified"=>1, "Materials Science"=>1, "Medicine and Dentistry"=>11, "Agricultural and Biological Sciences"=>3, "Neuroscience"=>1, "Psychology"=>3}, "reader_count_by_subdiscipline"=>{"Engineering"=>{"Engineering"=>1}, "Materials Science"=>{"Materials Science"=>1}, "Medicine and Dentistry"=>{"Medicine and Dentistry"=>11}, "Neuroscience"=>{"Neuroscience"=>1}, "Psychology"=>{"Psychology"=>3}, "Agricultural and Biological Sciences"=>{"Agricultural and Biological Sciences"=>3}, "Unspecified"=>{"Unspecified"=>1}}, "group_count"=>2}

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